Methylphen

Treating painful and irritating symptoms of the urinary tract due to urinary tract infections or diagnostic procedures.

Methylphen D/S is a urinary antiseptic, urinary acidifier, analgesic, and anticholinergic combination. It works by helping to kill bacteria in the urine, decreasing pain and inflammation, and reducing muscle spasms in the urinary tract. These actions work together to help relieve discomfort while urinating.

Hyoscyamine (Methylphen) produces many effects in the body, including relief from muscle spasms.

Methenamine (Methylphen) and Methylene blue (Methylphen) work as mild antiseptics that fight bacteria in the urine and bladder.

Phenyl salicylate (Methylphen) is a mild pain reliever.

Hyoscyamine (Methylphen), Methenamine (Methylphen), Methylene blue (Methylphen), and Phenyl salicylate (Methylphen) is a combination medicine used to treat bladder irritation (pain, burning, inflammation) caused by urinary tract infection. This medication is also used to prevent bladder discomfort during a medical procedure.

Hyoscyamine (Methylphen), Methenamine (Methylphen), Methylene blue (Methylphen), and Phenyl salicylate (Methylphen) may also be used for purposes not listed in this medication guide.

Usual Adult Dose for Urinary Tract Infection:

Hyoscyamine (Methylphen)/Methenamine (Methylphen)/Methylene blue (Methylphen)/Phenyl salicylate (Methylphen) 0.06 mg-81.6 mg-10.8 mg-36.2 mg oral enteric coated tablet:

1 tablet orally 4 times/day.

Hyoscyamine (Methylphen)/Methenamine (Methylphen)/Methylene blue (Methylphen)/Phenyl salicylate (Methylphen) 0.12 mg-100 mg-10.8 mg-40 mg oral capsule:

1 capsule orally 4 times/day.

Hyoscyamine (Methylphen)/Methenamine (Methylphen)/Methylene blue (Methylphen)/Phenyl salicylate (Methylphen) 0.12 mg-118 mg-10 mg-36 mg oral capsule:

1 capsule orally 4 times/day.

Hyoscyamine (Methylphen)/Methenamine (Methylphen)/Methylene blue (Methylphen)/Phenyl salicylate (Methylphen) 0.12 mg-81.6 mg-10.8 mg-36.2 mg oral enteric coated tablet:

1 tablet orally 4 times/day.

Usual Pediatric Dose for Urinary Tract Infection:

Hyoscyamine (Methylphen) 0.06 mg/Methenamine (Methylphen) 81.6 mg/Methylene blue (Methylphen) 10.8 mg/Phenyl salicylate (Methylphen) 36.2 mg enteric coated oral tablets:

12 yrs or older: 1 tablet orally 4 times/day.

See also:
What is the most important information I should know about Methylphen?

Do NOT use Methylphen D/S if:

you are allergic to any ingredient in Methylphen D/S

you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to aspirin, other salicylate medicines, or a nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen, naproxen, celecoxib)

you have angle-closure glaucoma, problems with your esophagus, bowel motility problems, a blockage of your bladder or bowel, severe intestinal problems (eg, ulcerative colitis), severe bleeding, flu or chickenpox, myasthenia gravis, severe kidney problems, or you are severely dehydrated

you are taking a sulfonamide (eg, sulfamethoxazole)

Contact your doctor or health care provider right away if any of these apply to you.

Use Methylphen as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Methylphen by mouth with or without food.
• Do not take an antacid or antidiarrheal medicine (eg, loperamide) within 1 hour before or after you take Methylphen.
• Drinking extra fluids while you are taking Methylphen is recommended. Check with your doctor for instructions.
• If you miss a dose of Methylphen, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Methylphen.

This medication is used to relieve the discomfort, pain, frequent urge to urinate, and cramps/spasms of the urinary tract caused by an infection or a medical procedure. Methenamine (Methylphen) is an antibiotic. Methylene blue (Methylphen) is an antiseptic and is related to a group of drugs called monoamine oxidase inhibitors (MAO inhibitors). Both Methenamine (Methylphen) and Methylene blue (Methylphen) help to prevent the growth of bacteria in the urine. Salicylate, which is related to aspirin, is a pain reliever. This product also contains an ingredient (such as sodium phosphate, benzoic acid) to make the urine more acidic, which helps Methenamine (Methylphen) work better. Hyoscyamine (Methylphen) is an antispasmodic drug that relaxes the muscles of the urinary tract to relieve cramps/spasms.

This product should not be used to treat a urinary tract infection. If you have a bacterial infection, another antibiotic is usually prescribed to treat it. Consult your doctor for more details.

This medication is not recommended for children younger than 6 years because they are more sensitive to the side effects.

How to use Methylphen

Take this medication by mouth as directed by your doctor, usually 4 times a day. Take each dose with a full glass of water (8 ounces/240 milliliters). Do not lie down for 10 minutes after taking this medication. Drink plenty of fluids while you are being treated with this medication unless otherwise directed by your doctor. If stomach upset occurs with this medication, you may take it with food.

The dosage is based on your medical condition, age, and response to treatment. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Antacids may decrease the absorption and the effectiveness of this product. Therefore, if you are also taking antacids, take this product at least 1 hour before antacids.

Take this medication regularly at evenly spaced intervals to get the most benefit from it. To help you remember, take it at the same times each day.

Caffeine can increase the side effects of this medication. Avoid drinking large amounts of beverages containing caffeine (coffee, tea, colas), eating large amounts of chocolate, or taking nonprescription products that contain caffeine.

Tell your doctor if your condition does not improve in a few days or if you develop signs of a urinary tract infection (such as burning/painful/frequent urination).

See also:
What other drugs will affect Methylphen?

Some MEDICINES MAY INTERACT with Methylphen D/S. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticholinergics (eg, benztropine) because they may increase the risk of Methylphen D/S ’s side effects

Ketoconazole because it may decrease Methylphen D/S ’s effectiveness

Monoamine oxidase inhibitors (MAOIs) or narcotic pain medicine (eg, codeine) because the risk of serious side effects may be increased

Medicine for myasthenia gravis (eg, ambenonium), phenothiazines (eg, chlorpromazine), sulfonamides (eg, sulfamethoxazole), thiazide diuretics (eg, hydrochlorothiazide), or urinary alkalinizers (eg, sodium bicarbonate) because their effectiveness may be decreased by Methylphen D/S

This may not be a complete list of all interactions that may occur. Ask your health care provider if Methylphen D/S may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

See also:
What are the possible side effects of Methylphen?

Nausea, vomiting, dry mouth, dizziness, drowsiness, blurred vision, or constipation may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.

This medication causes urine and sometimes stools to turn blue-green. This effect is harmless and will disappear when the medication is stopped.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: hot/dry/flushed skin, decreased sweating, eye pain, difficult urination, signs of kidney problems (such as change in the amount of urine, painful urination).

Get medical help right away if you have any very serious side effects, including: easy bruising/bleeding, black/tarry stools, stomach/abdominal pain, vomit that looks like coffee grounds, signs of liver problems (such as unusual tiredness, dark urine, persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin).

This drug may rarely cause an attack of extremely high blood pressure (hypertensive crisis), which may be fatal. Many drug interactions can increase this risk. Get medical help right away if any of these serious side effects occur: severe headache, fast/slow/irregular/pounding heartbeat, chest pain, neck stiffness/soreness, severe nausea/vomiting, sweaty/clammy skin (sometimes with fever), widened pupils, vision changes (such as double/blurred vision), sudden sensitivity to light (photophobia).

This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take. Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

A central nervous system stimulant used most commonly in the treatment of attention-deficit disorders in children and for narcolepsy. Its mechanisms appear to be similar to those of dextroamphetamine.