Machto

Each tablet/7 mL of suspension contains magnesium trisilicate 4.8-6.2 H₂O 300 mg, dried aluminium hydroxide gel 300 mg and activated dimethylpolysiloxane 25 mg.

Machto is a scientifically balanced formula which includes the combined benefits of 27 essential vitamins and minerals including folic acid, calcium, iron, the key antioxidants (betacarotene, C & E) and zinc.

Chewable caplet Adult 1-2 caplet. Childn 6-12 yr ½-1 caplet. Forte oral susp Adult 1-2 tsp. Childn 6-12 yr ½-1 tsp. All doses to be taken 3-4 times daily.

Severe renal function impairment due to the increased danger of occurrence of hypermag-

nesmia.

Appendicitis: since these products may increase the danger of perforation of rupture due to their constipation or laxative effects.

Patients with hypophosphatemia due to the phosphate binding properties of aluminium salts.

This medication is used to treat the symptoms of too much stomach acid such as stomach upset, heartburn, and acid indigestion. Aluminum and magnesium antacids work quickly to lower the acid in the stomach. Liquid antacids usually work faster/better than tablets or capsules.

This medication works only on existing acid in the stomach. It does not prevent acid production. It may be used alone or with other medications that lower acid production (e.g., H2 blockers such as cimetidine/ranitidine and proton pump inhibitors such as omeprazole).

How to use Machto

Take this medication by mouth, usually after meals and at bedtime as needed. Follow all the directions on the product package or use as directed by your doctor. If you are uncertain about any of this information, consult your doctor or pharmacist.

If you are taking the chewable tablets, chew thoroughly before swallowing, then drink a full glass of water (8 ounces or 240 milliliters).

If you are using the liquid form of this medication, shake the bottle well before pouring each dose. Refrigerating the suspension may improve the flavor. Do not freeze. The liquid form works best if taken without other fluids. You can mix your dose with a little water if needed.

This product may react with other medications (including digoxin, iron, pazopanib, tetracycline antibiotics, quinolone antibiotics such as ciprofloxacin), preventing them from being fully absorbed by your body. Talk with your doctor or pharmacist about how to schedule your medications to prevent this problem.

If your acid problems persist or worsen after you have used this product for 1 week, or if you think you have a serious medical problem, seek immediate medical attention. If you are using this medication regularly on a daily basis for more than 2 weeks, you may have a medical problem that needs different treatment. Ask your doctor whether this is the right medication for you.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: phosphate supplements (such as potassium phosphate), sodium polystyrene sulfonate.

Antacids can interfere with the absorption of many other drugs. Be sure to check with your pharmacist before taking antacids with any other medication.

This medication can cause nausea, constipation, diarrhea, or headache. If these symptoms persist or become severe, notify your doctor.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

The magnesium in this product can cause diarrhea. Using an antacid that contains only aluminum along with this product can help control diarrhea. The aluminum in this product can cause constipation. To minimize constipation, drink plenty of fluids and exercise. Diarrhea is more common with this product than constipation.

Aluminum-containing antacids bind to phosphate, an important body chemical, in the gut. This can cause low phosphate levels, especially if you use this medication in large doses and for a long time. Tell your doctor right away if you have any of the following symptoms of low phosphate: loss of appetite, unusual tiredness, muscle weakness.

Tell your doctor right away if any of these unlikely but serious side effects occur: dizziness, fainting.

Seek immediate medical attention if any of these rare but very serious side effects or symptoms of a serious medical problem occur: black/tarry stools, slow/shallow breathing, slow/irregular heartbeat, mental/mood changes (e.g., confusion), deep sleep, pain with urination, stomach/abdominal pain, vomit that looks like coffee grounds.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.