Components:
Medically reviewed by Kovalenko Svetlana Olegovna, PharmD. Last updated on 25.06.2022
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Lynestrenol is suitable for womwn when an oestrogen component is contra-indicated.
They are taken every day, with no interval during menstrual bleeding, but may be associated with the higher failure-rate than the combined preparations.
Oral
Contraception
Adult: 0.5 mg daily when used alone or 0.75-2.5 mg daily when used in combination with an oestrogen.
Oral
Menstrual disorders
Adult: 5-10 mg daily as cyclic regimen.
Lynestrenol is contraindicated in patients with undiagnosed vaginal bleeding, possible pregnancy, a past ectopic pregnancy, history of prutitus during pregnancy, herpes< or idiopathic jaundice, hormone-dependent neoplasms, severe liver impairment,
Dubin-Johnson syndrome and Rotor syndrome.
Irregular bleeding and reduced reliability may occur when Lynestrenol is used concomitantly with drugs such as anticonvulsants, barbiturates, rifampicin, activated charcoal and certain laxatives.
Oral contraceptives may diminish glucose tolerance and increase the need for insulin or other antidiabetic drugs in diabetes.
Many reports have been published of adverse effects associated with the use of oral contraceptives, the composition of which has changed with time.
There may be gastro-intestinal side-effects such as nausea or vomiting, chloasma and other skin or hair changes, headache, oedema, weight gain, and breast tenderness.
Spotting, breakthrough bleeding, or amenorrhoea can occur during treatment and amenorrhoea may also occur when oral contraceptives are withdrawn.
Intolerance to contact lenses hase been reported. Some patients may experience depression and other mental changes.