Lym-MX

The 4-methanol form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990).

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, Vitamin C (Lym-MX), functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C (Lym-MX) is considered an antioxidant.

Vitamin D3 (Lym-MX) (Vitamin D2) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond. It differs from cholecalciferol in having a double bond between C22 and C23 and a methyl group at C24.

Vit & mineral deficiencies during recovery, pregnancy, breastfeeding & elderly.

Magnesium (Lym-MX) Sulfate Injection, USP is suitable for replacement therapy in Magnesium (Lym-MX) deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those observed in hypocalcemia. In such cases, the serum Magnesium (Lym-MX) (Mg++) level is usually below the lower limit of normal (1.5 to 2.5 mEq/liter) and the serum calcium (Ca++) level is normal (4.3 to 5.3 mEq/liter) or elevated.

In total parenteral nutrition (TPN), Magnesium (Lym-MX) sulfate may be added to the nutrient admixture to correct or prevent hypomagnesemia which can arise during the course of therapy.

Magnesium (Lym-MX) Sulfate Injection, USP is also indicated for the prevention and control of seizures (convulsions) in pre-eclampsia and eclampsia, respectively.

* Sideroblastic anaemia

* Treatment and prophylaxis of Vitamin B6 (Lym-MX) deficiency states

For systemic use of Vitamin C (Lym-MX): prevention and treatment of hypo- and avitaminosis of Vitamin C (Lym-MX); providing increased need for Vitamin C (Lym-MX) during growth, pregnancy, lactation, with heavy loads, fatigue and during recovery after prolonged severe illness; in winter with an increased risk of infectious diseases.

For intravaginal use: chronic or recurrent vaginitis (bacterial vaginosis, nonspecific vaginitis) caused by the anaerobic flora (due to changes in pH of the vagina) in order to normalize disturbed vaginal microflora.

Vitamin D3 (Lym-MX) has an important role in energize the intestinal absorption for calcium and phosphor, to regulate their metabolism and balance in blood. It helps bone calcification. Deficiency of Vitamin D3 (Lym-MX) in the body causes deficiency of the calcium in the bone, weakness of its resistance and deformity.

Treating vitamin A deficiency. It may also be used for other conditions as determined by your doctor.

Beta-Carotene (Lym-MX) is a precursor to vitamin A, a fat-soluble vitamin.

• Beta-Carotene (Lym-MX) may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Beta-Carotene (Lym-MX). Use a sunscreen or protective clothing if you must be outside for a prolonged period.
• Your skin may turn slightly yellow while you are taking Beta-Carotene (Lym-MX). This is harmless and not a cause for concern.
• Do not take large doses of vitamins (megadoses or megavitamin therapy) while taking Beta-Carotene (Lym-MX) unless directed by your doctor.
• PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Beta-Carotene (Lym-MX) during pregnancy. If you are or will be breast feeding while you are using Beta-Carotene (Lym-MX), check with your doctor or pharmacist to discuss the risks to your baby.

Magnesium (Lym-MX) is used as a dietary supplement for individuals who are deficient in Magnesium (Lym-MX). Although a balanced diet usually supplies all the Magnesium (Lym-MX) a person needs, Magnesium (Lym-MX) supplements may be needed by patients who have lost Magnesium (Lym-MX) because of illness or treatment with certain medicines.

Lack of Magnesium (Lym-MX) may lead to irritability, muscle weakness, and irregular heartbeat.

Injectable Magnesium (Lym-MX) is given only by or under the supervision of a health care professional. Some oral Magnesium (Lym-MX) preparations are available only with a prescription. Others are available without a prescription.

Pyridoxine is Vitamin B6 (Lym-MX). Vitamins occur naturally in foods such as meat, poultry, nuts, whole grains, bananas, and avocados. Vitamin B6 (Lym-MX) is important for many processes in the body.

Pyridoxine is used to treat or prevent Vitamin B6 (Lym-MX) deficiency. It is also used to treat a certain type of anemia (lack of red blood cells). Pyridoxine injection is also used to treat some types of seizure in babies.

Pyridoxine taken by mouth (oral) is available without a prescription. Injectable pyridoxine must be given by a healthcare professional.

Pyridoxine may also be used for purposes not listed in this medication guide.

Ascorbic acid (Vitamin C (Lym-MX)) occurs naturally in foods such as citrus fruit, tomatoes, potatoes, and leafy vegetables. Vitamin C (Lym-MX) is important for bones and connective tissues, muscles, and blood vessels. Vitamin C (Lym-MX) also helps the body absorb iron, which is needed for red blood cell production.

Ascorbic acid is used to treat and prevent Vitamin C (Lym-MX) deficiency.

Ascorbic acid may also be used for purposes not listed in this medication guide.

Cholecalciferol is a Vitamin D3 (Lym-MX). Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Cholecalciferol is used to treat or prevent many conditions caused by a lack of vitamin D, especially conditions of the skin or bones.

Cholecalciferol may also be used for purposes not listed in this medication guide.

1 caplet daily.

Usual Adult Dose for Hypomagnesemia

500 to 1000 mg Magnesium (Lym-MX) gluconate (27 to 54 mg elemental Magnesium (Lym-MX)) orally 3 times a day.

Usual Adult Dose for Dietary Supplement

500 to 1000 mg Magnesium (Lym-MX) gluconate (27 to 54 mg elemental Magnesium (Lym-MX)) orally once a day.

Usual Pediatric Dose for Hypomagnesemia

10 to 20 mg/kg of elemental Magnesium (Lym-MX) per dose orally 4 times a day. Use Magnesium (Lym-MX) gluconate oral liquid preparations for more accurate measurement of dose.

Renal Dose Adjustments

Do not use without physician supervision in patients with renal impairment due to increased risk of hypermagnesemia. The use of Magnesium (Lym-MX) salts are generally contraindicated in patients with severe renal dysfunction.

Liver Dose Adjustments

Data not available

Dose Adjustments

May increase by 500 to 1,000 mg/day (27 to 54 mg elemental Magnesium (Lym-MX)) in order to achieve a normal serum Magnesium (Lym-MX) level. Daily doses > 1,000 mg (54 mg elemental Magnesium (Lym-MX)) should be given in 2 to 3 divided doses.

Precautions

Because Magnesium (Lym-MX) is primarily eliminated by the kidney, there is significant risk of hypermagnesemia in patients with renal dysfunction.

Dialysis

Data not available; however, use of Magnesium (Lym-MX) salts is generally contraindicated in renal failure.

Other Comments

Magnesium (Lym-MX) supplements are often used with "low normal" serum Magnesium (Lym-MX) levels in patients predisposed to hypomagnesemia (e.g., patients on diuretics).

This medication administered orally, IM, IV, intravaginally.

For the prevention of deficiency conditions Vitamin C (Lym-MX) dose is 25-75 mg / day, for the treatment - 250 mg / day or more in divided doses.

For intravaginal used ascorbic acid drugs in appropriate dosage forms.

1 tab daily.

See also:
What is the most important information I should know about Magnesium (Lym-MX)?

Do NOT use Calcium Carbonate/Magnesium (Lym-MX) Carbonate if:

you are allergic to any ingredient in Calcium Carbonate/Magnesium (Lym-MX) Carbonate

you have an increased calcium level in your blood

Contact your doctor or health care provider right away if any of these apply to you.

See also:
What is the most important information I should know about Vitamin B6 (Lym-MX)?

Contraindications for Vitamin B6 (Lym-MX) (Vitamin B6 (Lym-MX))

Vitamin B6 (Lym-MX) is contraindicated in those hypersensitive to any component of a Vitamin B6 (Lym-MX)-containing product.

See also:
What is the most important information I should know about Vitamin C (Lym-MX)?

AV-block II and III degree, sinoatrial block, SSS, bradycardia (HR < 40 bpm), hypotension (in case of myocardial infarction, systolic blood pressure less than 100 mm Hg), cardiogenic shock, congestive heart failure IIB-III stages, acute heart failure, Prinzmetal's angina, lactation, concomitant use of MAO inhibitors, hypersensitivity to atenolol.

See also:
What is the most important information I should know about Vitamin D3 (Lym-MX)?

Contraindications for vitamin D analogues (Vitamin D2, Vitamin D3 (Lym-MX), Calcitriol, and Calcidiol)

Vitamin D should not be given to patients with hypercalcemia or evidence of vitamin D toxicity. Use of vitamin D in patients with known hypersensitivity to vitamin D (or drugs of the same class) or any of the inactive ingredients is contraindicated.

Use Beta-Carotene (Lym-MX) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Beta-Carotene (Lym-MX) with food or milk.
• If you are unable to swallow a capsule, you may open it and mix the contents with orange juice or tomato juice. Drink the mixture immediately.
• Take Beta-Carotene (Lym-MX) regularly to receive the most benefit from it. Taking Beta-Carotene (Lym-MX) at the same time each day will help you remember to take it.
• If you miss a dose of Beta-Carotene (Lym-MX), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Beta-Carotene (Lym-MX).

Use Magnesium (Lym-MX) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Magnesium (Lym-MX) by mouth with food.
• If you miss a dose of Magnesium (Lym-MX) and are using it regularly, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Magnesium (Lym-MX).

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Pyridoxine tablets are taken by mouth. Injectable pyridoxine is injected into a muscle or into a vein through an IV. You may be shown how to use injections at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

The recommended dietary allowance of pyridoxine increases with age. Follow your healthcare provider's instructions. You may also consult the Office of Dietary Supplements of the National Institutes of Health, or the U.S. Department of Agriculture (USDA) Nutrient Database (formerly "Recommended Daily Allowances") listings for more information.

Pyridoxine is only part of a complete program of treatment that may also include a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you should eat or avoid to help control your condition.

Store at room temperature away from moisture and heat.

This medication is a mineral supplement used to prevent and treat low amounts of Magnesium (Lym-MX) in the blood. Magnesium (Lym-MX) is very important for the normal functioning of cells, nerves, muscles, bones, and the heart. Usually, a well-balanced diet provides normal blood levels of Magnesium (Lym-MX). However, certain situations cause your body to lose Magnesium (Lym-MX) faster than you can replace it from your diet. These situations include treatment with "water pills" (diuretics such as furosemide, hydrochlorothiazide), a poor diet, alcoholism, or other medical conditions (e.g., severe diarrhea/vomiting, stomach/intestinal absorption problems, poorly controlled diabetes).

How to use Magnesium (Lym-MX)

Take this product by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

It is best to take Magnesium (Lym-MX) supplements with a meal to reduce stomach upset and diarrhea unless otherwise directed by the product instructions or your doctor.

Take each dose with a full glass (8 ounces or 240 milliliters) of water unless your doctor directs you otherwise. Swallow extended-release capsules and delayed-release/enteric coated tablets or capsules whole. Do not crush or chew extended-release or delayed-release/enteric coated capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

If you are using a liquid product, use a medication measuring device to carefully measure the dose. Do not use a household spoon because you may not get the correct dose. If you are using a suspension, shake the bottle well before each dose.

Take this medication regularly in order to get the most benefit from it. Remember to take it at the same time(s) each day. Dosage is based on your medical condition and response to treatment. Do not increase your dose or take it more often than directed on the product package or by your doctor. Too much Magnesium (Lym-MX) in the blood can cause serious side effects.

Tell your doctor if symptoms of low Magnesium (Lym-MX) blood levels (e.g., muscle cramps, tiredness, irritability, depression) persist or worsen. If you think you may have a serious medical problem, seek immediate medical attention.

It is used for the treatment and prevention of Vitamin B6 (Lym-MX) deficiency. It is important for the breakdown of protein, fats, and carbohydrates from foods.

Ascorbic acid (Vitamin C (Lym-MX)) is used to prevent or treat low levels of Vitamin C (Lym-MX) in people who do not get enough of the vitamin from their diets. Most people who eat a normal diet do not need extra ascorbic acid. Low levels of Vitamin C (Lym-MX) can result in a condition called scurvy. Scurvy may cause symptoms such as rash, muscle weakness, joint pain, tiredness, or tooth loss.

Vitamin C (Lym-MX) plays an important role in the body. It is needed to maintain the health of skin, cartilage, teeth, bone, and blood vessels. It is also used to protect your body's cells from damage. It is known as an antioxidant.

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This vitamin may also be used with other vitamins for a certain eye condition (macular degeneration).

How to use Vitamin C (Lym-MX)

Take this vitamin by mouth with or without food, usually 1 to 2 times daily. Follow all directions on the product package, or take as directed by your doctor.

If you are taking the extended-release capsules, swallow them whole. Do not crush or chew extended-release capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. Take this product with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise.

If you are taking the wafers or chewable tablets, chew them thoroughly and then swallow. If you are taking the lozenges, place the lozenge in your mouth and allow it to slowly dissolve.

If you are taking the powder, mix it thoroughly in the proper amount of liquid and stir well. Drink all of the liquid right away. Do not prepare a supply for future use. If you are using the liquid form of this vitamin, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

Dosage is based on your medical condition and response to treatment.

Use this vitamin regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

If you think you may have a serious medical problem, seek immediate medical attention.

Vitamin D3 (Lym-MX) is used for the prevention and treatment of vitamin D deficiency. Vitamin D3 (Lym-MX) is important for absorption of calcium in the body. It is also used to prevent bone disorders such as osteomalacia and rickets.

Reduce levodopa effects; increase Fe absorption.

See also:
What other drugs will affect Magnesium (Lym-MX)?

Alfacalcidol: May increase the serum concentration of Magnesium (Lym-MX) Salts. Consider therapy modification

Alpha-Lipoic Acid: Magnesium (Lym-MX) Salts may decrease the absorption of Alpha-Lipoic Acid. Alpha-Lipoic Acid may decrease the absorption of Magnesium (Lym-MX) Salts. Consider therapy modification

Baloxavir Marboxil: Polyvalent Cation Containing Products may decrease the serum concentration of Baloxavir Marboxil. Avoid combination

Bictegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Bictegravir. Management: Administer bictegravir under fasting conditions at least 2 hours before or 6 hours after polyvalent cation containing products. Coadministration of bictegravir with or 2 hours after most polyvalent cation products is not recommended. Consider therapy modification

Bisphosphonate Derivatives: Polyvalent Cation Containing Products may decrease the serum concentration of Bisphosphonate Derivatives. Management: Avoid administration of oral medications containing polyvalent cations within: 2 hours before or after tiludronate/clodronate/etidronate; 60 minutes after oral ibandronate; or 30 minutes after alendronate/risedronate. Exceptions: Pamidronate; Zoledronic Acid. Consider therapy modification

Calcitriol (Systemic): May increase the serum concentration of Magnesium (Lym-MX) Salts. Management: Consider using a non-Magnesium (Lym-MX)-containing antacid or phosphate-binding product in patients also receiving calcitriol. If Magnesium (Lym-MX)-containing products must be used with calcitriol, serum Magnesium (Lym-MX) concentrations should be monitored closely. Consider therapy modification

Calcium Channel Blockers: May enhance the adverse/toxic effect of Magnesium (Lym-MX) Salts. Magnesium (Lym-MX) Salts may enhance the hypotensive effect of Calcium Channel Blockers. Monitor therapy

Deferiprone: Polyvalent Cation Containing Products may decrease the serum concentration of Deferiprone. Management: Separate administration of deferiprone and oral medications or supplements that contain polyvalent cations by at least 4 hours. Consider therapy modification

Dolutegravir: Magnesium (Lym-MX) Salts may decrease the serum concentration of Dolutegravir. Management: Administer dolutegravir at least 2 hours before or 6 hours after oral Magnesium (Lym-MX) salts. Administer the dolutegravir/rilpivirine combination product at least 4 hours before or 6 hours after oral Magnesium (Lym-MX) salts. Consider therapy modification

Doxercalciferol: May enhance the hypermagnesemic effect of Magnesium (Lym-MX) Salts. Management: Consider using a non-Magnesium (Lym-MX)-containing antacid or phosphate-binding product in patients also receiving doxercalciferol. If Magnesium (Lym-MX)-containing products must be used with doxercalciferol, serum Magnesium (Lym-MX) concentrations should be monitored closely. Consider therapy modification

Eltrombopag: Polyvalent Cation Containing Products may decrease the serum concentration of Eltrombopag. Management: Administer eltrombopag at least 2 hours before or 4 hours after oral administration of any polyvalent cation containing product. Consider therapy modification

Elvitegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Elvitegravir. Management: Administer elvitegravir 2 hours before or 6 hours after the administration of polyvalent cation containing products. Consider therapy modification

Gabapentin: Magnesium (Lym-MX) Salts may enhance the CNS depressant effect of Gabapentin. Specifically, high dose intravenous/epidural Magnesium (Lym-MX) sulfate may enhance the CNS depressant effects of gabapentin. Magnesium (Lym-MX) Salts may decrease the serum concentration of Gabapentin. Management: Administer gabapentin at least 2 hours after use of a Magnesium (Lym-MX)-containing antacid. Monitor patients closely for evidence of reduced response to gabapentin therapy. Monitor for CNS depression if high dose IV/epidural Magnesium (Lym-MX) sulfate is used. Consider therapy modification

Levothyroxine: Magnesium (Lym-MX) Salts may decrease the serum concentration of Levothyroxine. Management: Separate administration of oral levothyroxine and oral Magnesium (Lym-MX) salts by at least 4 hours. Consider therapy modification

Multivitamins/Fluoride (with ADE): Magnesium (Lym-MX) Salts may decrease the serum concentration of Multivitamins/Fluoride (with ADE). Specifically, Magnesium (Lym-MX) salts may decrease fluoride absorption. Management: To avoid this potential interaction separate the administration of Magnesium (Lym-MX) salts from administration of a fluoride-containing product by at least 1 hour. Consider therapy modification

Mycophenolate: Magnesium (Lym-MX) Salts may decrease the serum concentration of Mycophenolate. Management: Separate doses of mycophenolate and oral Magnesium (Lym-MX) salts. Monitor for reduced effects of mycophenolate if taken concomitant with oral Magnesium (Lym-MX) salts. Consider therapy modification

Neuromuscular-Blocking Agents: Magnesium (Lym-MX) Salts may enhance the neuromuscular-blocking effect of Neuromuscular-Blocking Agents. Monitor therapy

PenicillAMINE: Polyvalent Cation Containing Products may decrease the serum concentration of PenicillAMINE. Management: Separate the administration of penicillamine and oral polyvalent cation containing products by at least 1 hour. Consider therapy modification

Phosphate Supplements: Magnesium (Lym-MX) Salts may decrease the serum concentration of Phosphate Supplements. Management: Administer oral phosphate supplements as far apart from the administration of an oral Magnesium (Lym-MX) salt as possible to minimize the significance of this interaction. Exceptions: Sodium Glycerophosphate Pentahydrate. Consider therapy modification

Quinolones: Magnesium (Lym-MX) Salts may decrease the serum concentration of Quinolones. Management: Administer oral quinolones several hours before (4 h for moxi/pe/spar-, 2 h for others) or after (8 h for moxi-, 6 h for cipro/dela-, 4 h for lome/pe-, 3 h for gemi-, and 2 h for levo-, nor-, or ofloxacin or nalidixic acid) oral Magnesium (Lym-MX) salts. Exceptions: LevoFLOXacin (Oral Inhalation). Consider therapy modification

Raltegravir: Magnesium (Lym-MX) Salts may decrease the serum concentration of Raltegravir. Management: Avoid the use of oral / enteral Magnesium (Lym-MX) salts with raltegravir. No dose separation schedule has been established that adequately reduces the magnitude of interaction. Avoid combination

Tetracyclines: Magnesium (Lym-MX) Salts may decrease the absorption of Tetracyclines. Only applicable to oral preparations of each agent. Management: Avoid coadministration of oral Magnesium (Lym-MX) salts and oral tetracyclines. If coadministration cannot be avoided, administer oral Magnesium (Lym-MX) at least 2 hours before, or 4 hours after, oral tetracyclines. Monitor for decreased tetracycline therapeutic effects. Exceptions: Eravacycline. Consider therapy modification

Trientine: Polyvalent Cation Containing Products may decrease the serum concentration of Trientine. Management: Avoid concomitant administration of trientine and oral products that contain polyvalent cations. If oral iron supplements are required, separate the administration by 2 hours. If other oral polyvalent cations are needed, separate administration by 1 hour. Consider therapy modification

See also:
What other drugs will affect Vitamin B6 (Lym-MX)?

Interactions for Vitamin B6 (Lym-MX) (Vitamin B6 (Lym-MX))

Amiodarone: Concomitant use of Vitamin B6 (Lym-MX) and amiodarone may enhance amiodarone-induced photosensitivity reactions. Doses of Vitamin B6 (Lym-MX) greater than 5-10 milligrams/day should be avoided by those taking amiodarone Carbamazepine: Chronic use of carbamazepine may result in a significant decrease in plasma pyridoxal 5-phosphate levels Cycloserine: Cycloserine may react with pyridoxal 5-phosphate to form a metabolically inactive oxime, which may result in a functional Vitamin B6 (Lym-MX) deficiency Ethionamide: The use of ethionamide may increase Vitamin B6 (Lym-MX) requirements Fosphenytoin: High doses of Vitamin B6 (Lym-MX) may lower plasma levels of phenytoin. Fosphenytoin is a prodrug of phenytoin Hydralazine: The use of hydralazine may increase Vitamin B6 (Lym-MX) requirements Isoniazid: (isonicotinic acid, INH). Isoniazid reacts with pyridoxal 5-phosphate to form a metabolically inactive hydrazone, which may result in functional Vitamin B6 (Lym-MX) deficiency Levodopa: Concomitant use of levodopa and Vitamin B6 (Lym-MX) in doses of 5 milligrams or more daily may reverse the therapeutic effects of levodopa. Vitamin B6 (Lym-MX) does not reverse the therapeutic effects of levodopa if levodopa is taken concurrently with the levodopa decarboxylase inhibitor carbidopa. Levodopa is typically administered as a combination product with carbidopa

Oral contraceptives: The use of oral contraceptives may increase Vitamin B6 (Lym-MX) requirements. This was more the case with the older oral contraceptive agents with high-dose estrogen/progestin. It appears to be less the case with the newer low-dose estrogen/progestin products Penicillamine: Penicillamine may react with pyridoxal 5-phosphate to form a metabolically inactive thiazolidine, which may result in a functional Vitamin B6 (Lym-MX) deficiency Phenelzine: Phenelzine may react with pyridoxal 5-phosphate to yield a metabolically inactive hydrazone compound Phenobarbital: High doses of Vitamin B6 (Lym-MX) may lower plasma levels of phenobarbital Phenytoin: High doses of Vitamin B6 (Lym-MX) may lower plasma levels of phenytoin Theophylline: Theophylline may react with pyridoxal 5-phosphate leading to low plasma levels of the coenzyme. This may increase the risk of theophylline-induced seizures Valproic acid: Chronic use of valproic acid may result in a significant decrease in plasma pyridoxal 5-phosphate levels.

See also:
What other drugs will affect Vitamin C (Lym-MX)?

In an application with barbiturates, primidone increases the excretion of ascorbic acid in the urine.

With the simultaneous use of oral contraceptives reduces the concentration of ascorbic acid in blood plasma.

In an application of Vitamin C (Lym-MX) with iron preparations ascorbic acid, due to its regenerative properties, transforms ferric iron in the bivalent, which improves its absorption.

Ascorbic acid in high doses can decrease urine pH that while the application reduces the tubular reabsorption of amphetamine and tricyclic antidepressants.

With the simultaneous use of aspirin reduces the absorption of ascorbic acid by about a third.

Vitamin C (Lym-MX) in an application with warfarin may decrease effects of warfarin.

With the simultaneous application of ascorbic acid increases the excretion of iron in patients receiving deferoxamine. In the application of ascorbic acid at a dose of 500 mg / day possibly left ventricular dysfunction.

In an application with tetracycline is increased excretion of ascorbic acid in the urine.

There is a described case of reducing the concentration of fluphenazine in plasma in patients treated with ascorbic acid 500 mg 2 times / day.

May increase the concentration of ethinyl estradiol in the blood plasma in its simultaneous application in the oral contraceptives.

See also:
What other drugs will affect Vitamin D3 (Lym-MX)?

Interactions for vitamin D analogues (Vitamin D2, Vitamin D3 (Lym-MX), Calcitriol, and Calcidiol)

Cholestyramine

Cholestyramine has been reported to reduce intestinal absorption of fat soluble vitamins; as such it may impair intestinal absorption of any of vitamin D

Phenytoin/Phenobarbital

The coadministration of phenytoin or phenobarbital will not affect plasma concentrations of vitamin D, but may reduce endogenous plasma levels of calcitriol/ergocalcitriol by accelerating metabolism. Since blood level of calcitriol/ergocalcitriol will be reduced, higher doses of Rocaltrol may be necessary if these drugs are administered simultaneously

Thiazides

Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. Some reports have shown that the concomitant administration of thiazides with vitamin D causes hypercalcemia. Therefore, precaution should be taken when coadministration is necessary

Digitalis

Vitamin D dosage must be determined with care in patients undergoing treatment with digitalis, as hypercalcemia in such patients may precipitate cardiac arrhythmias

Ketoconazole

Ketoconazole may inhibit both synthetic and catabolic enzymes of vitamin D. Reductions in serum endogenous vitamin D concentrations have been observed following the administration of 300 mg/day to 1200 mg/day ketoconazole for a week to healthy men. However, in vivo drug interaction studies of ketoconazole with vitamin D have not been investigated

Corticosteroids

A relationship of functional antagonism exists between vitamin D analogues, which promote calcium absorption, and corticosteroids, which inhibit calcium absorption

Phosphate-Binding Agents

Since vitamin D also has an effect on phosphate transport in the intestine, kidneys and bones, the dosage of phosphate-binding agents must be adjusted in accordance with the serum phosphate concentration

Vitamin D

The coadministration of any of the vitamin D analogues should be avoided as this could create possible additive effects and hypercalcemia

Calcium Supplements

Uncontrolled intake of additional calcium-containing preparations should be avoided

Vitamin D3 (Lym-MX)

Vitamin D3 (Lym-MX)-containing preparations (eg, antacids) may cause hypermagnesemia and should therefore not be taken during therapy with vitamin D by patients on chronic renal dialysis.

See also:
What are the possible side effects of Beta-Carotene (Lym-MX)?

Beta-Carotene (Lym-MX) is generally well tolerated with a very low risk of toxicity. In contrast with vitamin A (excess intake of which may cause liver damage or birth defects), it is virtually impossible to overdose with Beta-Carotene (Lym-MX), as the body eliminates any of the latter substance which is surplus to requirements. No adverse effects have been reported in pregnant or lactating women taking up to 50,000IU/day, and intakes up to 1000mg/Kg body weight given to rats showed no long term toxic effects. Very high intake of Beta-Carotene (Lym-MX) (more than 100,000IU/day) may cause areas of the skin to take on an orange tone, which is harmless. Patients with diabetes, renal or liver disease, or with hyperthyroidism should take Beta-Carotene (Lym-MX) with caution.

See also:
What are the possible side effects of Magnesium (Lym-MX)?

The adverse effects of parenterally administered Magnesium (Lym-MX) usually are the result of Magnesium (Lym-MX) intoxication. These include flushing, sweating, hypotension, depressed reflexes, flaccid paralysis, hypothermia, circulatory collapse, cardiac and central nervous system depression proceeding to respiratory paralysis. Hypocalcemia with signs of tetany secondary to Magnesium (Lym-MX) sulfate therapy for eclampsia has been reported.

See also:
What are the possible side effects of Vitamin B6 (Lym-MX)?

Applies to pyridoxine: capsule, injectable, solution, tablet, tablet enteric coated, tablet extended release

As well as its needed effects, pyridoxine (the active ingredient contained in Vitamin B6 (Lym-MX)) may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking pyridoxine, check with your doctor or nurse as soon as possible:

With large doses

• Clumsiness
• numbness of hands or feet

See also:
What are the possible side effects of Vitamin C (Lym-MX)?

Applies to ascorbic acid: oral capsule, oral capsule extended release, oral capsule liquid filled, oral granule, oral liquid, oral lozenge/troche, oral powder, oral powder for solution, oral powder for suspension, oral solution, oral syrup, oral tablet, oral tablet chewable, oral tablet extended release, oral wafer

As well as its needed effects, ascorbic acid (the active ingredient contained in Vitamin C (Lym-MX)) may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking ascorbic acid, check with your doctor or nurse as soon as possible:

Less common or rare: - with high doses

• Side or lower back pain

Minor Side Effects

Some ascorbic acid side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common or rare: - with high doses

• Diarrhea
• dizziness or faintness (with the injection only)
• flushing or redness of skin
• headache
• increase in urination (mild)
• nausea or vomiting
• stomach cramps

See also:
What are the possible side effects of Vitamin D3 (Lym-MX)?

Applies to cholecalciferol: oral capsule, oral capsule liquid filled, oral solution, oral tablet, oral tablet chewable, oral wafer

As well as its needed effects, cholecalciferol (the active ingredient contained in Vitamin D3 (Lym-MX)) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking cholecalciferol, check with your doctor immediately:

Incidence not known:

• Cough
• difficulty swallowing
• dizziness
• fast heartbeat
• hives or itching
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• skin rash
• tightness in the chest
• unusual tiredness or weakness