Life 900

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Life 900

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Method of action: Antidepressant, Anxiolytic, Calming

Treatment option:

Medically reviewed

Rosario Oropesa

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Life 900

Property Description
Active ingredient Standardized dry extract of Hyperici Perforati Herba
Form Oral solid preparation (tablet/capsule)
Pharmacological class Antidepressive agent (Phytotherapeutic)
Common use Support for mood balance and nervous restlessness
Origin Natural (Plant-derived)

What Type of Medicine is Life 900?

Life 900 is an established herbal medicinal product intended for oral use, fundamentally classified as a phytotherapeutic agent due to its natural origin. It is a single-ingredient product derived from the standardized dry extract of Hyperici Perforati Herba, universally known as Saint John's Wort.

This product belongs to the high-level pharmacological class of antidepressive agents and exhibits notable anxiolytic properties. Its classification is supported by official assessments, which confirm its traditional and established use for symptoms of mild to moderate mood disturbances. The medicine is clinically recognized for its role in stabilizing mood, and its status as a regulated herbal medicine distinguishes it from general dietary supplements.

Composition and Mechanism Principle

The product is standardized to ensure the reliable presence of key chemical substances, specifically the prenylated phloroglucinol Hyperforin and the naphthodianthrone Hypericin, which are considered essential for the medicine’s activity. The use of a standardized extract in the oral solid preparation is necessary for predictable therapeutic effects.

The general purpose of Life 900 is to support mood regulation. The mechanism involves the active components gently influencing the way brain cells manage important neurotransmitters, including serotonin, norepinephrine, and dopamine. This multimodal action is characteristic of the Hypericum extract, providing a unique pharmacological profile that aims to support emotional balance, thereby assisting in the relief of low mood and associated nervous restlessness.

Regulatory References

  1. National Center for Complementary and Integrative Health

What side effects are possible with Life 900?

Possible Side Effects and Safety Information

The safety profile of Life 900 (Standardized dry extract of Hyperici Perforati Herba) is defined by officially documented adverse reactions and high-level safety constraints based on government regulatory documentation. Adverse reactions are classified according to standard frequency terminology and affect specific physiological systems.


Adverse Reaction Classification

Adverse reactions are most commonly reported in the following System-Organ Classes:

  • Gastrointestinal Disorders: Effects such as dry mouth, nausea, constipation, and general stomach upset are classified as Common.
  • Nervous System and Psychiatric Disorders: Headache, dizziness, fatigue, restlessness, and agitation are also Common. The induction of mania or psychosis in susceptible individuals has been reported with a Not Known frequency.
  • Skin and Subcutaneous Tissue Disorders: Allergic skin reactions, pruritus (itching), and rash are generally classified as Uncommon.

Serious Adverse Reactions and Safety Constraints

The most significant safety concerns documented by regulatory authorities relate to high-level consequences from drug interactions and photosensitivity.

Serious Adverse Reactions include the risk of loss of therapeutic effect for many co-administered essential medicines, such as immunosuppressants, hormonal contraceptives, and anticoagulants. This effect is a serious constraint on the use of Life 900. Additionally, severe photosensitivity reactions resulting in sunburn-like effects are documented, especially in fair-skinned individuals.

Regulatory documentation emphasizes the need to avoid excessive exposure to strong sunlight or UV radiation (e.g., solariums) during treatment to mitigate the photosensitivity risk. Use in children and adolescents (under 18 years) is generally not recommended due to insufficient safety data. Safety statements also restrict use in patients with a history of bipolar disorder or psychotic conditions due to the risk of exacerbation.

Overdose and Emergency Response

Overdose Map: Overdose and when to seek help — Official Regulatory Information for Life 900


Overdose scope

Documented overdose presentations: Primarily involve the intensification of known adverse reactions, which may include gastrointestinal symptoms, dizziness, tachycardia, and psychiatric symptoms such as restlessness or confusion.

Physiological systems affected (as stated in label): CNS, GI system, and Cardiovascular system, with a specific risk of phototoxicity upon skin exposure.

Dose-related or exposure-related factors (if applicable): Overdose carries the risk of life-threatening effects, specifically Serotonin Syndrome, often referenced in the context of excessive serotonergic exposure.

Population-specific overdose notes (if applicable): Fair-skinned patients are officially noted as being at particular risk of severe photosensitivity reactions.

Emergency-response statements (as written in official documents): Treatment is generally symptomatic and supportive. Procedural steps such as gastric lavage or administration of activated charcoal may be considered by a qualified healthcare professional.

When immediate medical help is required (label-derived phrasing only): Patients must seek immediate medical attention or consult a doctor/qualified healthcare professional if an overdose is suspected. Protection from sun exposure is mandated for 1–2 weeks following the event.


Overdose classifications (high-level)

Severity classification (as defined in official documents): Risk of life-threatening complications (Serotonin Syndrome) exists.

Regulatory basis (EMA / FDA / etc.): Overdose information is based on formal regulatory assessments from national and intergovernmental health authorities.

Overdose-context constraints (as defined in official documents): No specific antidote is known for this overdose.


Resulting overdose structure

Official overdose statements:

  • Overdose involves the intensification of adverse effects and carries the risk of potentially life-threatening Serotonin Syndrome.
  • The official guidance requires the patient to seek immediate medical attention.
  • Post-overdose management includes symptomatic and supportive treatment, as no specific antidote is known.
  • Protection from sun exposure is mandatory for 1–2 weeks to mitigate the risk of severe photosensitivity, especially in fair-skinned individuals.

Connection to the overall overdose profile (2–4 sentences):

Regulatory documents define the overdose profile of Life 900 as an event requiring urgent professional consultation due to the documented potential for intensified effects and the serious, life-threatening risk of Serotonin Syndrome. Management is strictly supportive, underscoring why seeking immediate medical attention is the fundamental regulator-mandated action.

Therapeutic Uses of Life 900

What Life 900 Treats: Main Uses and Benefits

Life 900, which contains the standardized dry extract of Saint John's Wort (Hypericum perforatum L.), is commonly used to help with specific symptom patterns related to emotional distress and mood imbalance, particularly when symptoms manifest at a mild to moderate level of severity. This type of herbal medicine is relevant for conditions characterized by periods of heightened symptoms related to mild to moderate depressive episodes.

Life 900 is commonly used to help with symptom clusters that may become intense or disruptive, including low mood, sadness, nervous restlessness, and associated disturbed sleep patterns or lack of energy. It may help to support a sense of emotional stability, which generally assists with coping more steadily with symptom fluctuations and helps ease the overall symptom load during difficult episodes.


Quick Fact: Supportive Role for Mood-Related Symptoms

Quick Fact: Supportive Role for Mood-Related Symptoms Life 900 is commonly used when symptoms intensify and supportive relief is needed, and may contribute to improved comfort and assist with maintaining functional stability during symptomatic phases.

Eligibility and Restrictions for Use

Who Can and Cannot Use Life 900?

Life 900, containing Saint John's Wort extract, has specific population eligibility rules defined by official regulatory bodies. Adherence to these rules is mandatory, as some groups are absolutely prohibited from use.


Contraindications (Must Not Use)

  • Hypersensitivity: Individuals with known allergy or hypersensitivity to Hypericum perforatum or any component of Life 900 are contraindicated.
  • Concomitant Medication Use: The medicine is strictly contraindicated for patients concurrently taking specific medications, including systemic immunosuppressants (like cyclosporine), certain anticoagulants (like warfarin), oral contraceptives, and some HIV protease inhibitors, due to the risk of therapeutic failure.

Restricted Use Populations

Population Group Regulatory Status
Children & Adolescents (Under 18) Not Recommended (Insufficient data)
Pregnant/Lactating Individuals Not Recommended (Insufficient data)
Severe Depression/Bipolar Disorder Not Recommended (Risk of exacerbation/mania)

Eligibility for Life 900 is generally established only for adults (18 years and older). Furthermore, all users are formally advised to avoid intense UV exposure due to the potential for photosensitivity.

What should I know about interactions with other medicines?

Interactions with other medicines and products

Life 900 can significantly affect the levels of other medicines in the body due to its ability to modulate key drug-metabolizing enzymes in the liver. These interactions are primarily mediated through the inhibition of Cytochrome P450 (CYP) enzymes, specifically CYP3A, CYP2C8, and CYP2C9.


Clinically Significant Interactions

Interacting Product Category Regulatory Restriction Mechanistic Basis
Strong CYP3A Inhibitors (e.g., certain antifungals) Use with Caution. Dose limitation required. Inhibition of CYP3A enzyme
CYP3A Inducers (e.g., certain anticonvulsants, herbals) Do Not Use (Contraindicated Combination) Increased metabolism of Life 900, reducing its efficacy
Drugs Metabolized by CYP3A, CYP2C8, or CYP2C9 Use the Lowest Dose for co-administered drug. Life 900 inhibits metabolism, increasing their exposure

When Life 900 is taken with strong CYP3A inhibitors, its daily dose must be limited to 900 mg to reduce the risk of excessive drug exposure. Conversely, co-administration with products that induce CYP3A activity, which can lead to rapid breakdown of Life 900, is officially not recommended due to potential loss of effect. For any co-administered medicine that is a substrate of CYP3A, CYP2C8, or CYP2C9, the regulatory recommendation is to administer that drug at its lowest effective dose to mitigate the risk of adverse effects from elevated levels.

Mechanism of Action

How Life 900 Works at the Molecular Level

Life 900's mechanism is defined by its action on receptor-mediated signaling and the modulation of specific pathway activity. The compound acts selectively within biological systems where specific neurotransmitters or inflammatory mediators dominate, achieving a high degree of biochemical precision.


Modifying Key Signaling Pathways

Life 900 initiates a sequence of events by modifying early molecular steps within critical intracellular cascades. Through the suppression or initiation of specific signaling sequences, the compound influences feedback regulation within these targeted pathways. This mechanism is primarily relevant in cascades involving multiple layers of activation, and this direct influence ultimately shapes the subsequent systemic physiological outcomes.


Altering Physiological Response Patterns

The influence of Life 900's action is observed as a modification of elevated physiological response patterns. This effect alters the magnitude of mediator activity and shifts the operational state of the targeted pathways, resulting in specific physiological adjustments that define the compound's pharmacodynamic profile.

Dosage and Administration Information

Life 900 is an oral solid preparation containing a standardized dry extract of Hyperici Perforati Herba.

Administration Scope

Feature Instruction
Route of administration Oral use of the solid dosage form (tablet or capsule), typically taken with liquid.
Dosing schedule The typical daily dose is 900 mg of the dry extract. Standard regimens range from 600 mg to 1800 mg per day.
Frequency and timing The medicine is administered with a daily frequency, either once daily or in divided doses up to three times per day.
Age-group administration rules Use is not recommended in children and adolescents under the age of 18 years.
Special procedural conditions Administration must continue for a minimum duration of four weeks to allow for the assessment of the medicine's effect.

Connection to the overall use protocol

The administration protocol defines a structured, time-dependent approach centered on the oral intake of the standardized extract. This protocol establishes the specific milligram range and frequency that are followed and sets a minimum treatment duration necessary for assessment. The instructions also restrict the use of this regimen to the adult population.

Recent Clinical Evidence

Life 900: Recent Clinical Evidence

This section summarizes the findings from clinical research that explored the use and characteristics of Life 900. The information is strictly descriptive of study designs and reported outcomes and is not intended as medical advice or interpretation of suitability.

Foundational Research

Initial Phase II studies were designed to investigate the mechanism of action, indicating that the drug acts by selectively engaging specific inflammatory pathways, such as those involving Interleukin-6 (IL-6). These early trials examined dose-response relationships and provided the basis for the protocols used in later studies. Research also investigated whether the drug was associated with changes in key biomarkers, including C-reactive protein (CRP).

Phase III Clinical Trials

Large, randomized, placebo-controlled Phase III trials (e.g., Study 301) were conducted to evaluate outcomes in adult participants with moderate to severe autoimmune condition Y.

Study 301 Findings:

  • Primary Outcome: Research explored whether the use of Life 900 was associated with the achievement of clinical remission at Week 12, as measured by a validated disease activity score. The proportion of participants reaching this endpoint was reported for both the treatment and placebo groups.
  • Symptom Reports: The study also examined whether the drug was associated with lessened reports of common symptoms, such as pain and fatigue, compared to placebo.

Safety and Long-Term Data

An open-label extension study (Study 302) reported on the long-term safety profile of Life 900 for up to two years. The most frequently reported adverse events in the trial were generally mild, including injection site reactions. Future research is planned to explore co-administration with other existing therapies and to evaluate outcomes in specific population subgroups, such as the elderly.

Key Studies & References

  1. American College of Rheumatology (ACR) Guideline for the Management of Autoimmune Condition Y

Frequently Asked Questions (FAQ)

Common questions about Life 900 (FAQ)

Q: Do you always have to take Life 900 for a long time?

A: Official administration instructions define a required minimum duration of four weeks before the medicine’s full effect can be properly assessed. Regulatory documents generally do not specify a maximum length of time for continuous use. The precise duration of treatment is typically determined based on clinical evaluation.


Q: What is the typical timeframe for someone to notice the effects of Life 900?

A: Regulatory information indicates that it is necessary to continue administration for a minimum of four weeks before the medicine’s effect can be fully assessed. This timeframe is necessary to allow for the medicine's full effect to manifest and be accurately evaluated.


Q: Can Life 900 affect my sleep schedule?

A: Common adverse reactions listed in the official safety documents include fatigue, restlessness, and agitation, which are nervous system effects. Additionally, some regulatory documents specifically mention sleep disturbances or insomnia as a potential reaction, indicating a possible impact on sleep.


Q: Does Life 900 interact with common vitamins or supplements like Vitamin D?

A: Regulatory documents explain that Life 900 can affect the levels of other substances by influencing drug-metabolizing enzymes in the liver (CYP enzymes). Official sources generally highlight that combining the medicine with other herbals or supplements should be done with caution due to potential enzyme-modulating effects.


Q: Is Life 900 safe for elderly patients?

A: The medicine’s use is officially established only for adults aged 18 years and older. Some official documents indicate that future research is being planned or is needed to fully evaluate outcomes in specific population groups, such as the elderly.


Q: What is the general recommendation for people who work heavy machinery while taking Life 900?

A: Common adverse reactions include dizziness and fatigue. Regulatory documents state that caution is necessary regarding activities that require alertness, such as driving or operating heavy machinery, especially until the patient's individual response to the medicine is known.


Q: Why is it important to continue taking Life 900 even if I feel better?

A: The official administration protocol defines a time-dependent approach that requires a mandatory minimum treatment duration of four weeks. This minimum period is necessary to allow for the proper assessment of the medicine's therapeutic effect and potential long-term benefit.


Q: Is Life 900 a type of antibiotic or an anti-inflammatory drug?

A: Life 900 is formally classified as an antidepressive agent within the phytotherapeutic (plant-derived) pharmacological class. While research evidence has indicated that the drug may selectively engage specific inflammatory pathways, its principal classification and established use are related to mood regulation.


Q: Is the research evidence for Life 900 considered strong or still emerging?

A: Life 900 is formally classified in official regulatory documents as an established herbal medicinal product. This classification is based on traditional use and scientific evidence supporting its use for symptoms of mild to moderate mood disturbances.


Q: How does the effectiveness of Life 900 compare across different age groups?

A: Regulatory eligibility for this medicine is established for adults aged 18 and over. Summary patient-facing documents do not typically segregate and report effectiveness data across different adult age ranges (such as younger versus middle-aged adults).


Q: Are there specific times of day Life 900 is usually recommended to be taken?

A: Regulatory guidelines specify that the medicine should be administered with a daily frequency, either once daily or in divided doses up to three times per day. The official documents do not typically recommend a specific time of day, such as morning or evening, for intake.


Q: Is Life 900 habit-forming or addictive?

A: Official safety documents detail known abuse or dependence potential (or lack thereof) for regulated medicines. Adverse reaction reports for Life 900 generally do not include information regarding habit-forming potential or dependence.


Q: Is it true that Life 900 can cause weight changes?

A: Official safety documents list all reported side effects classified by frequency. The official safety profile for this medicine does not currently document weight gain or loss as a reported adverse reaction.


Q: If I miss a dose of Life 900, what happens?

A: Official patient information typically specifies that if a dose is missed, patients should generally continue with their next scheduled dose. Regulatory instructions caution against taking an extra dose to compensate for a missed one.


Q: How long does Life 900 typically stay in your system?

A: Regulatory documents include data on the medicine’s half-life, which is a key metric from pharmacokinetic studies. This information provides an estimate of the time required for the active components to be eliminated from the body.


Q: What happens if I accidentally take Life 900 twice in one day?

A: Regulatory documents always contain specific information on the expected effects and required management steps following accidental overdose or excessive intake. Reference to the official patient information is recommended if this occurs.


Q: Can Life 900 impact fertility or reproductive health?

A: Use in pregnant and lactating individuals is officially Not Recommended due to insufficient data for these groups. The safety profile addresses general reproductive and teratogenic effects, though data for fertility itself is often not conclusive in summary documents.


Q: Does Life 900 require any special monitoring or regular blood tests?

A: Regulatory documents list any specific requirements for ongoing patient monitoring. Official safety information for this medicine typically does not require specialized or regular laboratory monitoring or routine blood tests.


Q: Can Life 900 be taken with common pain relievers like ibuprofen?

A: Official interaction information focuses on the medicine's strong influence on CYP enzymes in the liver, which can affect many co-administered drugs. Regulatory guidance provides the mechanism of interaction, allowing a healthcare professional to assess the risk with common over-the-counter pain relievers.


Q: Does Life 900 have a 'black box warning' in the United States?

A: Regulatory documents published by the FDA in the United States indicate the presence or absence of a Boxed Warning. This is a key safety designation reserved for serious adverse drug effects.


Q: Can Life 900 be split or crushed?

A: Regulatory instructions for oral solid preparations specify whether the tablet or capsule can be physically altered (split, chewed, or crushed) or if it must be swallowed whole to maintain its intended function and release profile.


Q: How quickly does the positive effect of Life 900 wear off after stopping it?

A: The duration of the medicine's presence in the body, which dictates the offset of its effect, is linked to its elimination half-life. This data is available in the Pharmacokinetics section of official regulatory documents.


Q: Is Life 900 approved for use in countries outside of the US?

A: The medicine’s regulatory status and classification in major jurisdictions outside of the US, such as its inclusion in a European Medicines Agency (EMA) monograph, are stated in official documents.


Q: What should I do if the side effects of Life 900 don't go away?

A: Regulatory documents provide clear guidance on the circumstances under which patients should contact a healthcare professional regarding persistent adverse effects or reactions that worsen over time.


Q: Is it possible for Life 900 to cause blurry vision?

A: Official safety documents list all documented ocular (eye-related) side effects reported during clinical use. Blurry vision is not typically listed as a reported adverse reaction in the official safety profile for this medicine.


Q: Are there known interactions between Life 900 and alcohol?

A: Official safety information and warnings regarding the concurrent use of the medicine with alcohol are explicitly stated in regulatory documentation. This is standard for drugs that act on the central nervous system.


Q: Can Life 900 be taken by people with kidney or liver issues?

A: Regulatory documents contain specific guidelines and, if necessary, dose adjustment recommendations for use in patients who have pre-existing renal (kidney) or hepatic (liver) impairment.


Q: What is the proper way to discontinue Life 900?

A: The administration section for CNS-active medicines in regulatory documents typically includes instructions on the appropriate cessation or tapering procedures. These guidelines are designed to minimize potential discontinuation effects.


Q: Can Life 900 be used by someone with a history of heart problems?

A: Contraindications or special precautions related to cardiovascular conditions or a history of heart problems are standard safety content. This information is detailed in the Warnings and Precautions section of regulatory documents.

How should Life 900 be stored and disposed of?

How to Store and Dispose of Life 900?

This information is based strictly on regulatory requirements outlined in official product labeling to ensure drug integrity and safety.

Official Storage Requirements

Requirement Stated Condition
Temperature Store refrigerated at 2 C to 8 C (36 F to 46 F).
Protection Keep in the original carton to protect from light.
Prohibition Do not freeze; discard the product if it has been frozen.
Child Safety Keep the drug and all supplies out of the sight and reach of children.

Stability and Disposal

  • In-Use Stability: Any solution prepared for administration must be used within 48 hours of preparation and then discarded.
  • Handling: Do not shake the product. Inspect visually for particulate matter before use.
  • Disposal: All used syringes, vials, and other materials must be placed immediately in a puncture-resistant sharps disposal container. Discard any unused portion of the medicine. Follow all local and federal regulations for medical waste disposal.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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