Lexivit

L-Lysine (Lexivit) (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. L-Lysine (Lexivit) is a base, as are arginine and histidine. The ε-amino group often participates in hydrogen bonding and as a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from Lysine (Lexivit) by lysyl hydroxylase. O-Glycosylation of Lysine (Lexivit) residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.

Niacinamide (Lexivit), also called as nicotinamide (vitamin B3), is prescribed for the treatment of niacin deficiency disorders including pellagra. Niacinamide (Lexivit) should not be used for treatment of hyperlipidemia.

Each 5 mL of syrup contains pure Taurine (Lexivit) 50 mg.

Each mL of infant drops contains pure Taurine (Lexivit) 50 mg, an amount comparable to that found in 1 L of human breast milk.

Vit B (Lexivit) contains specific active ingredients such as carnitine orotate and hepatic extract antitoxic fraction.

Each vial contains: Carnitine orotate 300 mg (equivalent to carnitine 152.4 mg and orotic acid 147.6 mg), carnitine HCl 184 mg (equivalent to carnitine base 150 mg), hepatic (liver) extract antitoxic fraction 25 mg (equivalent to cyanocobalamin 0.25 mcg), pyridoxine HCl (vitamin B₆) 25 mg, adenosine 5 mg, cyanocobalamin (vitamin B₁₂) 250 mcg.

Sometimes, there is color disproportion by physical properties during freeze-drying process but therapeutic effect is not affected.

Each teaspoonful (5 mL) of syrup contains vitamin C 83.33 mg, vitamin B1 8.33 mg, vitamin B6 1.67 mg, vitamin B12 8.33 mcg, riboflavin 4.16 mg, Vit C (Lexivit) 8.33 mg, dl-panthenol 3.33 mg, vitamin A 1500 units and vitamin D 100 units.

Each softgel capsule contains vitamin E 400 IU.

It also contains the following excipients: Soybean oil, gelatin, ethyl vanillin, methyl- and propylparaben.

Supplemental L-Lysine (Lexivit) has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.

Health food supplement to promote psychomotor development among infants and toddlers. To improve mental functioning and enhance memory of children. The child's partner in learning.

Multivit & Vit A (Lexivit) supplement for active growth, increased appetite, wt gain, enhanced body resistance to stress & infection.

Tab Prevention or treatment of Vit B (Lexivit)₁, B₆ & B₁₂ deficiencies. Forte tab Neuralgia, neuritis, diabetic neuropathy, sciatica, Vit B (Lexivit) deficiency, trigeminal neuralgia, intercostal neuralgia, hyperemesis gravidarum.

For systemic use of Vit C (Lexivit): prevention and treatment of hypo- and avitaminosis of vitamin C; providing increased need for vitamin C during growth, pregnancy, lactation, with heavy loads, fatigue and during recovery after prolonged severe illness; in winter with an increased risk of infectious diseases.

For intravaginal use: chronic or recurrent vaginitis (bacterial vaginosis, nonspecific vaginitis) caused by the anaerobic flora (due to changes in pH of the vagina) in order to normalize disturbed vaginal microflora.

Vitamin deficiencies, conditions of convalescence after a disease occurring with a feverish syndrome, high physical activity, older age, disease ligamentous system and muscles. Climacteric autonomic disorders. Neurasthenia with fatigue, asthenia neurasthenic syndrome, primary muscular dystrophy, posttraumatic, postinfectious secondary myopathy. Degenerative and proliferative changes in the joints and ligamentous apparatus spine and large joints.

Lysine (Lexivit) is an essential amino acid. Essential means that it is not produced by the body and therefore it must be taken in either by diet or by taking supplements. Lysine (Lexivit) is found in foods such as lentils, red meat, pork, poultry, cod fish, sardines, nuts, eggs, soy beans, brewer's yeast, and dairy products.

Lysine (Lexivit) has been used in alternative medicine as an aid to prevent cold sores around the mouth (caused by the herpes simplex virus). This product may make cold sores occur less often and may reduce the number of days a cold sore lasts. Lysine (Lexivit) is not a cure for herpes.

Other uses for Lysine (Lexivit) include treating metabolic acidosis, improving athletic performance, and helping the body absorb calcium supplements.

Not all uses for Lysine (Lexivit) have been approved by the FDA. Lysine (Lexivit) should not be used in place of medication prescribed for you by your doctor.

Lysine (Lexivit) is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Lysine (Lexivit) may also be used for purposes not listed in this product guide

Treating acne.

Niacinamide (Lexivit) gel is a vitamin B supplement. Exactly how Niacinamide (Lexivit) gel works is unknown.

• Niacinamide (Lexivit) gel is for external use only. Avoid getting Niacinamide (Lexivit) gel in your eyes. If you get Niacinamide (Lexivit) gel in your eyes, rinse thoroughly with cool tap water.
• Follow up with your doctor after 8 to 12 weeks to monitor your progress.
• Do not use any other medicines or special cleansers on your skin unless your doctor instructs you otherwise. Makeup and other acne medicines may be applied over Niacinamide (Lexivit) gel as directed by your doctor.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Niacinamide (Lexivit) gel while you are pregnant. It is not known if Niacinamide (Lexivit) gel is found in breast milk after topical use. If you are or will be breast-feeding while you use Niacinamide (Lexivit) gel, check with your doctor. Discuss any possible risks to your baby.

Oral

Treatment and prophylaxis of herpes simplex

Adult: To treat symptoms: 3,000-9,000 mg/day in divided doses. To prevent recurrences: 500-1,500 mg/day.

Oral

Dietary supplementation

Adult: 500-1,000 mg/day.

Applies to the following strengths: 100 mg; 500 mg

Usual Adult Dose for:

• Niacin Deficiency
• Pemphigus

Usual Pediatric Dose for:

• Niacin Deficiency
• Pemphigus

Additional dosage information:

• Renal Dose Adjustments
• Liver Dose Adjustments
• Dialysis
• Other Comments

Usual Adult Dose for Niacin Deficiency

Recommended Daily Allowances (RDA):

Males: 19 mg orally each day

Females: 13 mg orally each day

Initial dose: 100 mg orally 3 times a day, with or after meals

Maintenance dose: 100 to 500 mg orally up to 3 times a day, with or after meals

Niacinamide (Lexivit) has toxic potential at adult doses in excess of 3 g/day.

Niacinamide (Lexivit) may also be administered parenterally as a component of injectable multivitamin additives contained in parenteral nutrition products. All existing parenteral vitamin products for adults contain 40 mg/vial, which is the dose recommended by the American Medical Association/Nutrition Advisory Group for patients 11 years and older requiring parenteral vitamins.

Usual Adult Dose for Pemphigus

Recommended Daily Allowances (RDA):

Males: 19 mg orally each day

Females: 13 mg orally each day

Initial dose: 100 mg orally 3 times a day, with or after meals

Maintenance dose: 100 to 500 mg orally up to 3 times a day, with or after meals

Niacinamide (Lexivit) has toxic potential at adult doses in excess of 3 g/day.

Niacinamide (Lexivit) may also be administered parenterally as a component of injectable multivitamin additives contained in parenteral nutrition products. All existing parenteral vitamin products for adults contain 40 mg/vial, which is the dose recommended by the American Medical Association/Nutrition Advisory Group for patients 11 years and older requiring parenteral vitamins.

Usual Pediatric Dose for Niacin Deficiency

Recommended Daily Allowances (RDA):

0 to 6 months: 5 mg orally each day

6 months to 1 year: 6 mg orally each day

1 to 3 years: 9 mg orally each day

4 to 6 years: 12 mg orally each day

7 to 10 years: 13 mg orally each day

Males:

11 to 14 years: 17 mg orally each day

15 to 18 years: 20 mg orally each day

19 to 50 years: 19 mg orally each day

Females:

11 to 50 years: 13 mg orally each day

Niacinamide (Lexivit) may also be administered parenterally as a component of injectable multivitamin additives contained in parenteral nutrition products. All existing parenteral vitamin products for children contain 17 mg/vial, which is the dose recommended by the American Medical Association/Nutrition Advisory Group for patients under 11 years of age.

Usual Pediatric Dose for Pemphigus

Recommended Daily Allowances (RDA):

0 to 6 months: 5 mg orally each day

6 months to 1 year: 6 mg orally each day

1 to 3 years: 9 mg orally each day

4 to 6 years: 12 mg orally each day

7 to 10 years: 13 mg orally each day

Males:

11 to 14 years: 17 mg orally each day

15 to 18 years: 20 mg orally each day

19 to 50 years: 19 mg orally each day

Females:

11 to 50 years: 13 mg orally each day

Niacinamide (Lexivit) may also be administered parenterally as a component of injectable multivitamin additives contained in parenteral nutrition products. All existing parenteral vitamin products for children contain 17 mg/vial, which is the dose recommended by the American Medical Association/Nutrition Advisory Group for patients under 11 years of age.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Because Niacinamide (Lexivit) is primarily metabolized by the liver and because of the risk of hepatotoxicity, Niacinamide (Lexivit) in not recommended in patients with liver dysfunction.

Dialysis

Data not available

Other Comments

Taking Niacinamide (Lexivit) with food may reduce stomach upset.

Niacinamide (Lexivit) should not be taken with hot drinks.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

More about Niacinamide (Lexivit)

• Niacinamide (Lexivit) Side Effects
• During Pregnancy
• Drug Interactions
• Support Group
• 1 Review
• Drug class: vitamins

Consumer resources

• Niacinamide (Lexivit)
• Niacinamide (Lexivit) Extended-Release Tablets

Related treatment guides

• Niacin Deficiency
• Pemphigus

Syrup: Children 7-12 years: 5-10 mL (1-2 tsp); 2-6 years: 5 mL (1 tsp). All doses to be taken once a day.

Oral Drops:

Childn 7-12 yr 15 mL, 3-6 yr 10 mL, 1-2 yr 5 mL. To be taken once daily.

Inject 2 vials/day through IV instillation after dissolving each vial of the freeze-dried cake with 4 mL water for injection.

Administration: Vit B (Lexivit) can be administered by LVP instillation process by diluting the solution to LVP solution. When using the LVP solution as diluent for Vit B (Lexivit) injection, it has to be cautioned that the LVP solution must be non-electrolyte LVP (eg, 5% dextrose solution). If the electrolyte-containing LVP solution (eg, Ringer's solution) is used, carnitine orotate will precipitate in the solution.

It is recommended that in the administration method, diluted LVP solution must be used because direct instillation without dilution can induce serious pain in the injection site.

As much as possible, inject slowly because blood vessel pain may occur during IV injection.

This medication administered orally, IM, IV, intravaginally.

For the prevention of deficiency conditions Vit C (Lexivit) dose is 25-75 mg / day, for the treatment - 250 mg / day or more in divided doses.

For intravaginal used ascorbic acid drugs in appropriate dosage forms.

Adults: One soft cap daily.

Cystic Fibrosis: 100-200 mg of dl-α-tocopheryl acetate or about 67-135 mg of dl-α-tocopherol.

Abetalipoproteinaemia: 50-100 mg of dl-α-tocopheryl acetate/kg body weight or about 33-67 mg of dl-α-tocopherol/kg.

See also:
What is the most important information I should know about Lysine (Lexivit)?

L-Lysine (Lexivit) supplementation is contraindicated in those with the rare genetic disorder hyperlysinemia/hyperlysinuria.

Hypersensitivity.

Hypersensitivity. Large doses (>1 g daily) of vit C in patients w/ G6PD deficiency. History of renal calculi, hyperoxaluria, oxalate dysbolism & thalassemia. Patients w/ Vit A (Lexivit) redundancy.

Hypersensitivity to any of the components of Vit B (Lexivit).

Increased sensitivity to ascorbic acid.

Hypersensitivity to vitamin E or to any of the components of Vit E (Lexivit).

Use Niacinamide (Lexivit) gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Wash the affected area with a mild cleanser or other cleansing product prescribed by your doctor and completely dry.
• Apply a thin layer of the medicine to the affected area twice daily or as directed by your doctor. Gently rub the medicine in until it is evenly distributed.
• Wash your hands immediately after using Niacinamide (Lexivit) gel.
• If you miss a dose of Niacinamide (Lexivit) gel, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Niacinamide (Lexivit) gel.

Herpes simplex infections.

To treat Hartnup disease (light sensitive skin rashes), inflammatory skin disease, vitamin deficiency, anxiety and Alzheimer’s disease (disorder that causes mental confusion and forgetfulness). It is also used in combination with intravenous vitamin C therapy for cancer.

See also:
What other drugs will affect Lysine (Lexivit)?

Since Lysine (Lexivit) does not alter clonixinate coagulation, no interaction with anticoagulant drugs and do not require dose adjustments. Concomitant use of anticholinergic drugs to be avoided by the possibility that they enhance their effects atropine.

Vit E increases absorption of Vit A (Lexivit). Inhibits absorption & function of vit K w/ high doses of vit E. Reduced effects of vit E w/ Fe prep. Reduced absorption of Vit A (Lexivit) & E w/ cholestyramine & liqd paraffin.

High doses of Vit B (Lexivit)₆ may decrease the actions of L-dopa.

In an application with barbiturates, primidone increases the excretion of ascorbic acid in the urine.

With the simultaneous use of oral contraceptives reduces the concentration of ascorbic acid in blood plasma.

In an application of Vit C (Lexivit) with iron preparations ascorbic acid, due to its regenerative properties, transforms ferric iron in the bivalent, which improves its absorption.

Ascorbic acid in high doses can decrease urine pH that while the application reduces the tubular reabsorption of amphetamine and tricyclic antidepressants.

With the simultaneous use of aspirin reduces the absorption of ascorbic acid by about a third.

Vit C (Lexivit) in an application with warfarin may decrease effects of warfarin.

With the simultaneous application of ascorbic acid increases the excretion of iron in patients receiving deferoxamine. In the application of ascorbic acid at a dose of 500 mg / day possibly left ventricular dysfunction.

In an application with tetracycline is increased excretion of ascorbic acid in the urine.

There is a described case of reducing the concentration of fluphenazine in plasma in patients treated with ascorbic acid 500 mg 2 times / day.

May increase the concentration of ethinyl estradiol in the blood plasma in its simultaneous application in the oral contraceptives.

Vitamin E increases the absorption, intake and storage of vitamin A, and may protect against the vitamin A redundancy disease. However these effects have not been established yet.

The use of vitamin E dosages >10 IU/kg body weight may slow response to the iron therapy in children suffering from iron deficiency anemia. Vitamin E deficiency in children treated with iron supplements may result to hemolytic anemia. Vitamin E and its metabolites may protect against the action of vitamin K. Patients who take oral anticoagulants have risk of hemorrhage after taking the large dose of vitamin E. In healthy volunteers, vitamin E did not change the blood clotting process.

Excessive use of mineral oil may decrease the vitamin E absorption.

See also:
What are the possible side effects of Lysine (Lexivit)?

Adverse effects associated with the mechanics of retrograde genitourinary procedures include injury to the urethra, bladder, and ureter, and introduction of infection. {03} {06} {31}

Systemic adverse effects, similar to those that occur with direct intravascular injection of the diatrizoate salts, may also occur with intravesical or intraureteral instillation as a result of inadvertent intravascular entry of the contrast solution due to either bladder absorption or pyelorenal backflow. {06} {31}

Systemic adverse effects, although rare, are possible with intrauterine instillation if medium is absorbed systemically after being retained in the uterine cavity or spilled into the peritoneal cavity. {06} {34}

The following side/adverse effects have been selected on the basis of their potential clinical significance (possible signs and symptoms in parentheses where appropriate)—not necessarily inclusive

See also:
What are the possible side effects of Niacinamide (Lexivit)?

Applies to Niacinamide (Lexivit): tablets

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; itching; nausea; stomach upset; temporary feeling of warmth or flushing of the skin.

Seek medical attention right away if any of these SEVERE side effects occur while taking Niacinamide (Lexivit):

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry, or bloody stools; changes in vision; dark urine; decreased urination; fast or irregular heartbeat; loss of appetite; muscle pain or weakness; numbness or persistent tingling of the skin; persistent nausea, vomiting, or general "unwell" feeling; severe or prolonged flushing of the skin; stomach pain; swelling of the hands, legs, or feet; vomit that looks like coffee grounds; yellowing of the skin or eyes.

Nausea, vomiting, diarrhoea.

Long-term use of large doses of Vit B (Lexivit)₆ may lead to severe peripheral neuropathies.

CNS: headache, fatigue, insomnia.

Digestive system: stomach cramps, nausea and vomiting.

Allergic reaction: describes a few cases of skin reactions and manifestations of the respiratory system.

Urinary system: when used in high doses - hyperoxaluria and the formation of kidney stones of calcium oxalate.

Local reactions: with intravaginal application - a burning or itching in the vagina, increased mucous discharge, redness, swelling of the vulva. Other: sensation of heat.

Vitamin E is usually well tolerated. Large doses of vitamin E may cause diarrhea, abdominal pain, other gastrointestinal disturbances, and have also been reported to cause fatigue and weakness.