L-Trepein

A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. [PubChem]

A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.

Saturated solution of Potassium Iodide (L-Trepein) (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperglycemia (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.

Vitamin B12 (L-Trepein) (commonly known as Vitamin B12 (L-Trepein)) is the most chemically complex of all the vitamins. Vitamin B12 (L-Trepein)'s structure is based on a corrin ring, which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded. The central metal ion is Co (cobalt). Vitamin B12 (L-Trepein) cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of cyanocobalamin are bacteria and archaea. Higher plants do not concentrate cyanocobalamin from the soil and so are a poor source of the substance as compared with animal tissues. Vitamin B12 (L-Trepein) is naturally found in foods including meat (especially liver and shellfish), eggs, and milk products.

The 4-methanol form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990).

Recurrent mouth ulcers, denture irritation, toothache, infant teething pain, sore gum.

It is used to make the urine more acidic. Making the urine more acidic helps to relieve skin irritation in incontinent (loss of bladder control) adults and diaper rash in infants. This medicine also helps to control strong urine odor.

Potassium Iodide (L-Trepein) is oral antithyroid agent. Potassium Iodide (L-Trepein) is used as an adjunct to other antithyroid agents in the treatment of hyperthyroidism and thyrotoxicosis and preoperatively to induce thyroid involution. (radiation poisoning;)

Pernicious anemia, both uncomplicated and accompanied by nervous system involvement.

Dietary deficiency of Vitamin B12 (L-Trepein), occurring in strict vegetarians and in their breast-fed infants. (Isolated Vitamin B12 (L-Trepein) deficiency is very rare).

Malabsorption of Vitamin B12 (L-Trepein), resulting from structural or functional damage to the stomach, where intrinsic factor is secreted or to the ileum, where intrinsic factor facilitates Vitamin B12 (L-Trepein) absorption. These conditions include tropical sprue, and nontropical sprue (idiopathic steatorrhea, gluten-induced enteropathy). Folate deficiency in these patients is usually more severe than Vitamin B12 (L-Trepein) deficiency.

Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy). Total gastrectomy always produces Vitamin B12 (L-Trepein) deficiency.

Structural lesions leading to Vitamin B12 (L-Trepein) deficiency include regional ileitis, ileal resections, malignancies, etc.

Competition for Vitamin B12 (L-Trepein) by intestinal parasites or bacteria.

The fish tapeworm (Diphyilobothrium latum) absorbs huge quantities of Vitamin B12 (L-Trepein) and infested patients often have associated gastric atrophy. The blind-loop syndrome may produce deficiency of Vitamin B12 (L-Trepein) or folate.

Inadequate utilization of Vitamin B12 (L-Trepein). This may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia.

For the Schilling Test.

* Sideroblastic anaemia

* Treatment and prophylaxis of Vitamin B6 (L-Trepein) deficiency states

Racemethionine is used to make the urine more acidic. Making the urine more acidic helps to relieve skin irritation in incontinent (loss of bladder control) adults and diaper rash in infants. Methionine (L-Trepein) also helps to control strong urine odor.

Racemethionine is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, racemethionine may be used to treat acetaminophen poisoning when the preferred medicine for treatment is not available.

Potassium Iodide (L-Trepein) is the potassium salt form of iodide, a naturally occurring substance.

Potassium Iodide (L-Trepein) can be used as an expectorant to thin mucus and loosen congestion in your chest and throat.

Potassium Iodide (L-Trepein) is used in people with chronic breathing problems that can be complicated by thick mucus in the respiratory tract, such as asthma, chronic bronchitis, or emphysema.

Potassium Iodide (L-Trepein) may also be used for purposes not listed in this medication guide.

Cyanocobalamin is a man-made form of Vitamin B12 (L-Trepein). Vitamin B12 (L-Trepein) is important for growth, cell reproduction, blood formation, and protein and tissue synthesis.

Cyanocobalamin is used to treat Vitamin B12 (L-Trepein) deficiency in people with pernicious anemia and other conditions.

Cyanocobalamin may also be used for purposes not listed in this medication guide.

Pyridoxine is Vitamin B6 (L-Trepein). Vitamins occur naturally in foods such as meat, poultry, nuts, whole grains, bananas, and avocados. Vitamin B6 (L-Trepein) is important for many processes in the body.

Pyridoxine is used to treat or prevent Vitamin B6 (L-Trepein) deficiency. It is also used to treat a certain type of anemia (lack of red blood cells). Pyridoxine injection is also used to treat some types of seizure in babies.

Pyridoxine taken by mouth (oral) is available without a prescription. Injectable pyridoxine must be given by a healthcare professional.

Pyridoxine may also be used for purposes not listed in this medication guide.

Usual Adult Dose for Cough

300 to 650 mg orally 3 to 4 times a day.

Usual Adult Dose for Hyperthyroidism

Oral solution: 250 mg orally 3 times a day. Give for 10 to 14 days prior to thyroid surgery.

May be given as 0.25 mL of a 1 g/mL potassium iodine solution (SSKI) or as 4 mL of 325 mg/5 mL solution. Alternatively, 2 to 6 drops of a 10% Potassium Iodide (L-Trepein)/5% iodine solution may be given orally 3 times a day with food.

Usual Adult Dose for Cutaneous Sporotrichosis

250 to 500 mg orally 3 times a day. Increase gradually to a maximum of 2 to 2.5 grams 3 times a day. Continue at maximum tolerated dose until the cutaneous lesions have resolved, usually 6 to 12 weeks.

Usual Adult Dose for Radiation Emergency

Pregnant or lactating women with exposure >= 5 centigrays (cGy): 130 mg orally per day.

>18 and <=40 years with exposure >= 10 centigrays (cGy): 130 mg orally per day.

>40 years with exposure >= 500 centigrays (cGy): 130 mg orally per day.

Usual Pediatric Dose for Cough

60 to 250 mg orally every 4 to 6 times a day. Maximum single dose 500 mg.

Usual Pediatric Dose for Hyperthyroidism

Oral solution: 250 mg orally 3 times a day. Give for 10 to 14 days prior to thyroid surgery.

Usual Pediatric Dose for Cutaneous Sporotrichosis

250 to 500 mg orally 3 times a day. Increase gradually to a maximum of 1.25 to 2 grams 3 times a day. Continue at maximum tolerated dose until the cutaneous lesions have resolved, usually 6 to 12 weeks.

Usual Pediatric Dose for Radiation Emergency

<=1 month with exposure >= 5 centigrays (cGy): 16 mg orally per day.

>1 month <=3 years with exposure >= 5 centigrays (cGy): 32 mg orally per day.

>3 years <= 18 years (less than 70 kg) with exposure >= 5 centigrays (cGy): 65 mg orally per day.

>13 years >= 70 kg with exposure >= 5 centigrays (cGy): 130 mg orally per day.

Renal Dose Adjustments

Potassium Iodide (L-Trepein) should be used cautiously in patients with renal dysfunction. Due to impaired renal filtering of electrolytes, an increase in serum potassium can occur in patients with renal impairment.

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Other Comments

Administer after meals with food or milk or dilute with a large quantity of water, fruit juice, or broth.

Vitamin B12 (L-Trepein) Atlantic Laboratories is used as injections SC, IV, IM, intralumbar, and also oral. With anemia associated with Vitamin B12 (L-Trepein) deficiency is introduced on 100-200 mcg in 2 days. In anemia with symptoms of funicular myelosis and megalocytic anemia with diseases of the nervous system - 400-500 micrograms in the first 7 days daily, then 1 time every 5-7 days. In the period of remission in the absence of events funicular myelosis maintenance dose - 100 mcg 2 times a month, in the presence of neurological symptoms - at 200-400 mcg 2-4 times a month. In acute post-hemorrhagic anemia and iron anemia by 30-100 mcg 2-3 times a week. When aplastic anemia (especially in children) - 100 micrograms before clinical improvement. When nutritional anemia in infants and preterm - 30 mcg / day during 15 days.

In diseases of the central and peripheral nervous system and neurological diseases with a pain syndrome is administered in increasing doses - 200-500 mcg, with the improvement in the state - 100 mcg / day. The course of treatment with Vitamin B12 (L-Trepein) Atlantic Laboratories is 2 weeks. In traumatic lesions of peripheral nervous system - at 200-400 mcg every other day for 40-45 days.

When hepatitis and cirrhosis - 30-60 mcg / day or 100 mg every other day for 25-40 days.

Dystrophy in young children, Down syndrome and cerebral palsy - by 15-30 mcg every other day.

When funicular myelosis, amyotrophic lateral sclerosis can be introduced into the spinal canal at 15-30 mcg, gradually increasing the dose of 200-250 micrograms.

In radiation sickness, diabetic neuropathy, sprue - by 60-100 mcg daily for 20-30 days.

When deficiency of Vitamin B12 (L-Trepein) to prevent - IV or IM for 1 mg 1 time a month; for treatment - IV or IM for 1 mg daily for 1-2 weeks, the maintenance dose is 1-2 mg IV or IM from 1 per week, up to 1 per month. Duration of treatment is determined individually.

See also:
What is the most important information I should know about Methionine (L-Trepein)?

L-Methionine (L-Trepein) is contraindicated in those with the genetic disorder homocystinuria. It is also contraindicated in those who are hypersensitive to any component of a Methionine (L-Trepein)-containing product.

See also:
What is the most important information I should know about Potassium Iodide (L-Trepein)?

Hypersensitivity to iodide, iodine, or any component of the formulation; dermatitis herpetiformis; hypocomplementemic vasculitis, nodular thyroid condition with heart disease

See also:
What is the most important information I should know about Vitamin B12 (L-Trepein)?

Hypersensitivity to the components of the formula. History of allergy to the cobalamins (Vitamin B12 (L-Trepein) and similar substances). Malignant tumors. By stimulating the growth of tissues, the Cobamamide could increase the high rate of cell multiplication. Sensitivity to cobalt. History of allergies to cobalamin (Vitamin B12 (L-Trepein) and related substances).

- Malignant tumor: Due to the action of Vitamin B12 (L-Trepein) on the growth of tissue cell multiplication rate high, the risk of exacerbation should be taken into account.

- Children under 6 years because of the dosage form

See also:
What is the most important information I should know about Vitamin B6 (L-Trepein)?

Contraindications for Vitamin B6 (L-Trepein) (Vitamin B6 (L-Trepein))

Vitamin B6 (L-Trepein) is contraindicated in those hypersensitive to any component of a Vitamin B6 (L-Trepein)-containing product.

Use Methionine (L-Trepein) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Methionine (L-Trepein) with or following a meal.
• If you have difficulty swallowing the capsules, they may be dissolved in juice, water, or warm milk.
• If you miss a dose of Methionine (L-Trepein), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Methionine (L-Trepein).

Use Potassium Iodide (L-Trepein) solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Potassium Iodide (L-Trepein) solution. Talk to your pharmacist if you have questions about this information.
• Take Potassium Iodide (L-Trepein) solution by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Use the dropper that comes with Potassium Iodide (L-Trepein) solution to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you are instructed to take more than 1 dose of Potassium Iodide (L-Trepein) solution, do NOT take it sooner than 24 hours after the last dose of Potassium Iodide (L-Trepein) solution. Do NOT take more than 1 dose per day.
• If you miss a dose of Potassium Iodide (L-Trepein) solution, take it as soon as possible. If you are instructed to take more than 1 dose of Potassium Iodide (L-Trepein) solution and it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.

Ask your health care provider any questions you may have about how to use Potassium Iodide (L-Trepein) solution.

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Pyridoxine tablets are taken by mouth. Injectable pyridoxine is injected into a muscle or into a vein through an IV. You may be shown how to use injections at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

The recommended dietary allowance of pyridoxine increases with age. Follow your healthcare provider's instructions. You may also consult the Office of Dietary Supplements of the National Institutes of Health, or the U.S. Department of Agriculture (USDA) Nutrient Database (formerly "Recommended Daily Allowances") listings for more information.

Pyridoxine is only part of a complete program of treatment that may also include a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you should eat or avoid to help control your condition.

Store at room temperature away from moisture and heat.

Potassium Iodide (L-Trepein) is used to loosen and break up mucus in the airways. This helps you cough up the mucus so you can breathe more easily if you have long-term lung problems (e.g., asthma, chronic bronchitis, emphysema). This medication is known as an expectorant.

Potassium Iodide (L-Trepein) is also used along with antithyroid medicines to prepare the thyroid gland for surgical removal, to treat certain overactive thyroid conditions (hyperthyroidism), and to protect the thyroid in a radiation exposure emergency. It works by shrinking the size of the thyroid gland and decreasing the amount of thyroid hormones produced.

In a radiation emergency, Potassium Iodide (L-Trepein) blocks only the thyroid from absorbing radioactive iodine, protecting it from damage and reducing the risk of thyroid cancer. Use this medication along with other emergency measures that will be recommended to you by public health and safety officials (e.g., finding safe shelter, evacuation, controlling food supply).

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This drug may also be used to treat a certain type of fungal skin infection (sporotrichosis).

How to use Potassium Iodide (L-Trepein)

Take this medication by mouth with a full glass of water (8 ounces or 240 milliliters) as directed by your doctor or public health and safety officials. To avoid stomach upset, take after meals or with food. Drink plenty of liquids with this medication unless otherwise directed. If you are taking the tablets, do not lie down for 10 minutes after taking this medication. If you are using the drops or liquid medication, use the dropper that comes with the bottle or a medication spoon/device to measure the correct dose. Liquid forms of this product may be mixed in water, milk, formula, or juice before taking. Do not use this medication if the solution turns brownish-yellow.

Dosage is based on your medical condition and response to therapy. In children, dosage is also based on age. Do not increase your dose, take it more often, or take it for longer than prescribed or recommended because of the increased risk of side effects.

In a radiation emergency, take this drug only when public health and safety officials tell you to do so. Read the Patient Information Leaflet that comes with the medication. Start treatment as soon as possible for the best protection. Take this medication usually once every 24 hours. The length of treatment will be determined by public health and safety officials and depends on several factors (e.g., whether you continue to be exposed to the radiation, and whether you are pregnant, breast-feeding, or have a newborn baby). See also Precautions.

If so directed, use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Inform your doctor if your condition persists or worsens.

It is used for the treatment and prevention of Vitamin B6 (L-Trepein) deficiency. It is important for the breakdown of protein, fats, and carbohydrates from foods.

Acetaminophen and methotrexate - L-Methionine (L-Trepein) may decrease hepatic toxicity in those with acetaminophen overdosage or in those taking methotrexate. Theoretically, it may decrease hepatic toxicity in the case of other potential hepatotoxic drugs, as well. Gentamicin - Methionine (L-Trepein) may protect against the ototoxic effects of gentamicin.

See also:
What other drugs will affect Potassium Iodide (L-Trepein)?

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: ACE inhibitors (e.g., captopril, lisinopril), angiotensin receptor blockers (ARBs such as losartan, valsartan), certain "water pills" (potassium-sparing diuretics such as amiloride, spironolactone, triamterene), drospirenone, eplerenone, lithium, potassium-containing drugs (e.g., supplements such as potassium chloride).

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

See also:
What other drugs will affect Vitamin B12 (L-Trepein)?

In an application of Vitamin B12 (L-Trepein) Atlantic Laboratories with hormonal contraceptives for oral administration may decrease the concentration of cyanocobalamin in plasma.

In an application with anticonvulsant drugs decreased cyanocobalamin absorption from the gut.

In an Vitamin B12 (L-Trepein) Atlantic Laboratories application with neomycin, aminosalicylic acid, colchicine, cimetidine, ranitidine, drugs potassium decreased cyanocobalamin absorption from the gut.

Cyanocobalamin may exacerbate allergic reactions caused by thiamine.

When parenteral application of chloramphenicol may decrease the hematopoietic effects of cyanocobalamin with anemia.

See also:
What other drugs will affect Vitamin B6 (L-Trepein)?

Interactions for Vitamin B6 (L-Trepein) (Vitamin B6 (L-Trepein))

Amiodarone: Concomitant use of Vitamin B6 (L-Trepein) and amiodarone may enhance amiodarone-induced photosensitivity reactions. Doses of Vitamin B6 (L-Trepein) greater than 5-10 milligrams/day should be avoided by those taking amiodarone Carbamazepine: Chronic use of carbamazepine may result in a significant decrease in plasma pyridoxal 5-phosphate levels Cycloserine: Cycloserine may react with pyridoxal 5-phosphate to form a metabolically inactive oxime, which may result in a functional Vitamin B6 (L-Trepein) deficiency Ethionamide: The use of ethionamide may increase Vitamin B6 (L-Trepein) requirements Fosphenytoin: High doses of Vitamin B6 (L-Trepein) may lower plasma levels of phenytoin. Fosphenytoin is a prodrug of phenytoin Hydralazine: The use of hydralazine may increase Vitamin B6 (L-Trepein) requirements Isoniazid: (isonicotinic acid, INH). Isoniazid reacts with pyridoxal 5-phosphate to form a metabolically inactive hydrazone, which may result in functional Vitamin B6 (L-Trepein) deficiency Levodopa: Concomitant use of levodopa and Vitamin B6 (L-Trepein) in doses of 5 milligrams or more daily may reverse the therapeutic effects of levodopa. Vitamin B6 (L-Trepein) does not reverse the therapeutic effects of levodopa if levodopa is taken concurrently with the levodopa decarboxylase inhibitor carbidopa. Levodopa is typically administered as a combination product with carbidopa

Oral contraceptives: The use of oral contraceptives may increase Vitamin B6 (L-Trepein) requirements. This was more the case with the older oral contraceptive agents with high-dose estrogen/progestin. It appears to be less the case with the newer low-dose estrogen/progestin products Penicillamine: Penicillamine may react with pyridoxal 5-phosphate to form a metabolically inactive thiazolidine, which may result in a functional Vitamin B6 (L-Trepein) deficiency Phenelzine: Phenelzine may react with pyridoxal 5-phosphate to yield a metabolically inactive hydrazone compound Phenobarbital: High doses of Vitamin B6 (L-Trepein) may lower plasma levels of phenobarbital Phenytoin: High doses of Vitamin B6 (L-Trepein) may lower plasma levels of phenytoin Theophylline: Theophylline may react with pyridoxal 5-phosphate leading to low plasma levels of the coenzyme. This may increase the risk of theophylline-induced seizures Valproic acid: Chronic use of valproic acid may result in a significant decrease in plasma pyridoxal 5-phosphate levels.

Flushing, Gastrointestinal disturbance, Decreased white blood cell count

See also:
What are the possible side effects of Methionine (L-Trepein)?

Along with its needed effects, a medicine may cause some unwanted effects. Side effects that may occur during racemethionine therapy usually do not need medical attention. They may go away during treatment as your body adjusts to the medicine. Check with your doctor if any of the following side effects continue or are bothersome:

More common

Drowsiness; nausea and vomiting

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

See also:
What are the possible side effects of Potassium Iodide (L-Trepein)?

Applies to Potassium Iodide (L-Trepein): oral solution, oral syrup

In addition to its needed effects, some unwanted effects may be caused by Potassium Iodide (L-Trepein) (the active ingredient contained in Potassium Iodide (L-Trepein)). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Potassium Iodide (L-Trepein), check with your doctor or nurse as soon as possible:

Less common:

• Hives
• joint pain
• swelling of arms, face, legs, lips, tongue, and/or throat
• swelling of lymph glands

• Burning of mouth or throat
• confusion
• headache (severe)
• increased watering of mouth
• irregular heartbeat
• metallic taste
• numbness, tingling, pain or weakness in hands or feet
• soreness of teeth and gums
• sores on skin
• symptoms of head cold
• unusual tiredness
• weakness or heaviness of legs

Minor Side Effects

Some of the side effects that can occur with Potassium Iodide (L-Trepein) may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:

• Diarrhea
• nausea or vomiting
• stomach pain

See also:
What are the possible side effects of Vitamin B12 (L-Trepein)?

Applies to cyanocobalamin: intramuscular solution

Other dosage forms:

• nasal gel/jelly, nasal spray

As well as its needed effects, cyanocobalamin (the active ingredient contained in Vitamin B12 (L-Trepein)) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking cyanocobalamin, check with your doctor or nurse immediately:

Incidence not known:

• Abdominal or stomach pain
• bleeding from the gums or nose
• blue lips and fingernails
• chest pain
• cough
• coughing that sometimes produces a pink frothy sputum
• decreased urine output
• difficult, fast, noisy breathing, sometimes with wheezing
• difficulty with swallowing
• dilated neck veins
• dizziness
• extreme fatigue
• eye pain
• fast heartbeat
• headache
• hives, itching, or skin rash
• increased sweating
• irregular breathing
• irregular heartbeat
• pale skin
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• ringing in the ears
• swelling of the face, fingers, feet, or lower legs
• tightness in the chest
• unusual tiredness or weakness
• weight gain

Minor Side Effects

Some cyanocobalamin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Incidence not known:

• Diarrhea
• skin rash with a general disease

See also:
What are the possible side effects of Vitamin B6 (L-Trepein)?

Applies to pyridoxine: capsule, injectable, solution, tablet, tablet enteric coated, tablet extended release

As well as its needed effects, pyridoxine (the active ingredient contained in Vitamin B6 (L-Trepein)) may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking pyridoxine, check with your doctor or nurse as soon as possible:

With large doses

• Clumsiness
• numbness of hands or feet