Korodin

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Korodin

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Medically reviewed

Laura Arias

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Korodin

Property Description
Active Ingredients Camphor, Hawthorn (Crataegus extract)
Form Oral solution (drops)
Pharmacological Class Cardiac and circulatory preparation
Common Use Support for functional circulatory complaints
Origin Derived product (Natural compound + Herbal extract)

What Type of Medicine is Korodin?

Korodin is a proprietary combination drug and phytotherapeutic agent administered as oral solution drops. It is broadly classified as a cardiac and circulatory preparation intended for systemic support of the cardiovascular system and is widely available non-prescription. This medicine is a derived product that pairs Camphor (a monoterpene) with a complex herbal extract from Hawthorn (Crataegus species). This specific dual composition, which is recognized for supporting minor circulatory issues, distinguishes it from both single-herb remedies and potent synthetic cardiovascular medications. Its liquid form is optimized for rapid oral intake when functional circulatory symptoms arise.


Active Ingredients: Camphor and Hawthorn Extract

The preparation contains two distinct active ingredients: Camphor and Hawthorn fluid extract. These components are specifically formulated in an ethanolic solution to ensure their stability and optimal absorption. Hawthorn extract contributes natural constituents, including flavonoids and proanthocyanidins, that are associated with cardiovascular benefit. Crataegus preparations are recognized for their long-standing use in supporting cardiac function. This indicates the Hawthorn component has pharmacological recognition for helping the heart work more efficiently.


General Purpose: Circulatory Support

The general purpose of Korodin is to provide gentle support and stabilization for blood circulation. It is specifically intended as an aid for managing general functional circulatory complaints, such as temporary feelings of dizziness or lightheadedness upon standing, which are common manifestations of mild circulatory weakness. The combined action of Camphor and Hawthorn is characterized by a capacity to help maintain appropriate vascular tone while gently supporting the overall function of the heart muscle. The formulation serves as a supportive tool for individuals seeking to maintain circulatory regulation and vitality.

Regulatory References

  1. NCCIH: Hawthorn - Usefulness and Safety

What side effects are possible with Korodin?

The official safety profile for this combination medicine, containing Camphor and Hawthorn extract, is structured by regulatory authorities to define potential adverse reactions and mandatory limitations for use.

Officially Documented Adverse Reactions

Adverse reactions associated with this medication are generally classified as rare or occurring only in exceptional cases (less than 1 in 1,000 treated patients). The reported effects belong to specific system-organ classes:

  • Skin and Immune System: The possibility of allergic skin reactions or hypersensitivity reactions to the active substances or excipients is documented.
  • Gastrointestinal System: General gastrointestinal complaints have been reported.
  • Respiratory System: The camphor component carries a risk of triggering a spasm of the vocal cords (laryngospasm) or an asthma attack in susceptible individuals, which are classified as serious adverse reactions.

Safety Restrictions and Special Populations

Regulatory documents define specific populations where the medicine must not be used (contra-indicated) or where use is not recommended due to safety concerns or lack of data.

  • Infants and Toddlers (under 2 years): The medicine is contra-indicated in this age group due to the risk of laryngospasm caused by D-camphor.
  • Respiratory Conditions: It is contra-indicated in patients with bronchial asthma or other severe respiratory diseases where the risk of triggering an asthma attack is present.
  • Pregnancy and Breast-feeding: Use is not recommended in these situations due to insufficient data to rule out risk to the child.
  • Other Restrictions: The high ethanol (alcohol) content must be considered for patients with a history of alcoholism, liver disease, or epilepsy.

This regulatory framework mandates strict limitations for use in sensitive populations and clearly defines the expected frequency and nature of possible side effects.

Overdose and Emergency Response

Overdose and when to seek help

Official regulatory documentation on overdose focuses on the acute toxicity profile of the camphor component. Overdose may manifest with severe central nervous system effects, including seizures (convulsions), tremors, agitation, and hallucinations. Documented gastrointestinal presentations include abdominal pain, nausea, and vomiting. More severe manifestations can escalate to unconsciousness and carry a documented risk of death from oral ingestion. Furthermore, the profile notes potential for associated liver damage.

When to Seek Urgent Medical Attention

The regulatory guidance is explicit that immediate medical help must be sought upon any suspected overdose. Emergency services or the Poison Help hotline should be contacted immediately, as referral to an emergency department is required for any severe symptoms or ingestion exceeding a dose of 30, mg/kg. Children are noted to be more sensitive to toxic effects and face a heightened risk of seizures and fatality.

Supportive Measures

The official management protocol states that no specific antidote is known. Treatment is purely symptomatic and supportive, focusing on stabilizing the patient. Specific regulatory instructions for management include controlling convulsions, typically with a benzodiazepine, and providing necessary airway support. Official guidance explicitly states not to induce vomiting and notes that hospital observation for vital sign monitoring may be required.

Therapeutic Uses of Korodin

What Korodin Treats: Main Uses and Benefits

This medication is commonly used to provide symptomatic relief from circulatory regulation disorders and symptoms of low blood pressure (hypotension). The therapeutic focus is on easing distressing symptoms, particularly those related to changes in body position, known as orthostatic symptoms.

The medicine is relevant for managing symptom clusters associated with circulatory weakness, including dizziness, lightheadedness, faintness, pallor, fatigue, and lack of drive. In clinical contexts where additional symptomatic support is needed, the product is applied to address these therapeutic domains. It offers symptomatic relief that may help patients cope more steadily with these difficult episodes and provides supportive relief when symptoms interfere with routine activities.

It is applied in scenarios where additional management of discomfort is required during phases of heightened symptoms. By assisting with maintaining functional stability, this may contribute to improved day-to-day comfort during symptomatic periods and supports general well-being.


Quick Fact

Quick Fact: Relief for Dizziness upon Standing

Eligibility and Restrictions for Use

Who can and cannot use Korodin?

The official eligibility profile for Korodin drops is strictly defined by regulatory mandates based on age, composition risks, and certain pre-existing conditions. Only adults (18 years and older) are approved for standard use.

Korodin is contraindicated and must not be used by the following populations:

  • Infants and Toddlers (Under 2 years): Prohibited due to the established risk of laryngospasm associated with the D-camphor content.
  • Respiratory Patients: Contraindicated for individuals with bronchial asthma or pronounced respiratory tract hypersensitivity.
  • Hypersensitivity: Prohibited for anyone with a known allergy to D-camphor, Hawthorn, or other excipients.

Use is not recommended for other vulnerable populations due to a lack of established safety and efficacy data:

  • Children and Adolescents (Under 18 years): Not recommended for use.
  • Pregnancy and Lactation: Use is not recommended during pregnancy and should not be taken while breastfeeding.

Conditional Caution is mandated for patients with comorbidities sensitive to the high alcohol content (60% v/v) of the solution. This includes individuals with alcoholism, liver disease, or epilepsy, where the ethanol content must be taken into account.

What should I know about interactions with other medicines?

The official regulatory documentation for Korodin establishes that no interactions with other medicinal products are currently known. This determination classifies the product as having no documented drug–drug interactions with other prescription or non-prescription medicines. The regulatory profile does include a specific clarification regarding co-administration with a potentially interacting class: the simultaneous use of Cardiac Glycosides is formally stated as possible and permissible according to the product labeling.

This combination drug is not associated with documented pharmacokinetic or metabolic interactions, such as those mediated by CYP enzymes or drug transporters. Furthermore, the regulatory documents do not specify any mandatory timing-based rules that require separation of administration from other substances, nor are there any explicitly classified contraindicated medicinal combinations.

However, a required restriction is noted regarding the product's excipient. Korodin is an ethanolic solution containing 60 Vol.-% Alcohol. This high alcohol content requires formal consideration in specific patient populations. The official label specifies that a health risk exists for patients suffering from alcoholism. Additionally, the alcohol content must be specifically considered for patients with an increased risk due to liver disease. The regulatory context for this product is thus defined by the formal absence of known drug-drug effects and a required constraint based on the product’s ethanol component.

Mechanism of Action

Korodin acts through the synergistic pharmacodynamic mechanisms of its two active components, D-camphor and hawthorn fruit extract, to influence key cardiovascular regulatory pathways.

D-Camphor-Mediated Signaling in Central Circulation

D-camphor engages mechanisms that directly influence central circulatory control via stimulation of the vasomotor center in the medulla oblongata. This initiates a rapid adjustment of systemic vascular resistance and arterial pressure regulation. This effect is primarily engaged in systems requiring rapid, short-term modulation of systemic perfusion.

Influence on Myocardial Contractility and Vascular Signaling

The hawthorn fruit extract component acts through bioflavonoids and procyanidins to modulate signaling pathways in cardiac myocytes and the vasculature. Mechanistic effects include a slight positive inotropic effect (increased contractility) and vasorelaxation mediated by enhanced nitric oxide synthesis. This action influences the regulation of processes driven by distinct signaling patterns, resulting in altered coronary vascular resistance and modified stroke volume.

Dosage and Administration Information

The administration of Korodin oral solution follows specific guidelines concerning route, dosage, frequency, and preparation. This medicine is administered via oral intake in drop form.


Administration Schedule and Dose

The general usage pattern for adults specifies a routine dose of 10 drops to be taken three times daily. For episodes of temporary circulatory weakness, the dosing frequency changes to an intermittent schedule where 5 to 10 drops may be administered every 15 minutes until relief is observed. A maximum of 25 drops for a single adult dose should not be exceeded. The medicine is suitable for long-term supportive therapy, provided the underlying symptoms persist.


Preparation and Delivery Method

The method of intake is a specific requirement for this formulation. The drops must be administered undiluted on a piece of sugar or bread (for patients with diabetes), which should then be chewed slowly to facilitate absorption. The solution must not be mixed with water for consumption. Furthermore, consuming water is to be avoided for five minutes immediately before and after taking the dose. The preparation must never be inhaled.


Population-Specific Rules

Use of the medicine is subject to explicit age-group constraints. The medicine is not for use in infants and toddlers under two years old. Furthermore, it is not generally recommended for children and adolescents under the age of 18 due to insufficient data for these groups.

Recent Clinical Evidence

Research Evidence / Overview of Studies for Korodin

The research investigated areas related to circulatory function and systemic balance and was studied for symptoms related to temporary low blood pressure, particularly those that happen when a person stands up.


Evidence for Use in Functional Circulatory Complaints

Research has examined the use of this combination product in individuals experiencing conditions characterized by fluctuating or episodic manifestations of circulatory weakness, such as orthostatic hypotension. The core of the evidence base consists of Randomized Controlled Trials (RCTs), which compare participants against a placebo, and are synthesized in systematic reviews and meta-analyses. Findings indicate that the product was studied for its capacity to influence blood pressure metrics in the short term. The pooled data from multiple RCTs reported measurements of differences in average blood pressure readings compared to placebo.


What Outcomes Have Clinical Trials Measured?

Clinical trials research examined both objective and subjective changes. Researchers focused on hemodynamic variables, including the change in Mean Arterial Blood Pressure (MAP) after standing up. These measurements are used in research examining temporary changes in the body's circulatory response. Studies also monitored patient-reported outcomes describing perceived discomfort, such as the severity and frequency of dizziness and faintness, and outcomes reflecting daily functioning.


What Remains Uncertain and Research Gaps

Regulatory summaries and systematic reviews acknowledge that while the evidence exists, its overall volume is limited in the broader context of clinical research. The key limitations documented include: Sample sizes were modest in the randomized trials; the long-term effects are not fully established; the optimum dose and duration of treatment is still unclear; and differences in response after a single-dose application were not always statistically certain.

Key Studies & References

  1. D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly - a randomized, placebo controlled double blind study
  2. The effect of Camphor-Crataegus berry extract combination on blood pressure and mental functions in chronic hypotension--a randomized placebo controlled double blind design

Frequently Asked Questions (FAQ)

Common questions about Korodin (FAQ)


Q: Is Korodin a prescription-only medicine, or can I buy it over the counter?

A: According to the official product information, this medicine is classified as non-prescription. This means that a doctor's order is not required to obtain it. However, in many locations, it is designated as 'pharmacy-only,' meaning it must be obtained directly from a licensed pharmacy.


Q: How quickly can one expect Korodin to start having an effect?

A: The regulatory dosing schedule for temporary circulatory weakness allows for repeat doses every 15 minutes until relief is observed. This acute dosing pattern indicates that a quick effect is expected according to the product’s official usage instructions. Some official data or study context suggests the action is expected to be rapid.


Q: Is the effect of Korodin immediate or does it build up over time?

A: The official product labeling indicates that Korodin is suitable for managing both acute symptoms and for use in long-term supportive therapy. This suggests the medicine is officially intended for both a quick initial effect and for ongoing use when symptoms persist.


Q: Is Korodin considered safe for older adults?

A: The official eligibility profile specifies adult use (18 years and older). Clinical research has specifically examined the product's effect on patients 50 years and older who experience circulatory weakness. No upper age restrictions are officially specified.


Q: Why is the active ingredient dissolved in an alcohol-based liquid?

A: The medicine is formulated as an ethanolic solution primarily because D-camphor, one of the active ingredients, is not water-soluble. The alcohol is necessary to dissolve this component and also helps ensure the overall stability of the medicine. This also aligns with the official preparation guidelines, which state that the drops should not be mixed with water.


Q: Does Korodin lose its effectiveness if used for many months?

A: Official regulatory labeling indicates that the duration of use is generally not limited in time and the medicine is suitable for longer-term supportive therapy. This classification suggests that a loss of effectiveness or tolerance is not a stated concern when the medicine is used as described.


Q: Does Korodin contain any alcohol or sugar?

A: The medicine officially contains a high percentage of alcohol (60 Vol.-% Alcohol) in its formulation. However, the product itself does not contain sugar as an ingredient. Sugar is only listed in the official preparation instructions as a suggested medium on which to place the drops for easier intake.


Q: Is it common for people to feel slightly dizzy after taking Korodin?

A: Dizziness is a key symptom of the circulatory complaints this product is intended to support. The documented adverse reactions listed in the official safety profile are classified as rare or exceptional and do not list dizziness as a reported side effect of the medicine.


Q: Can Korodin cause problems with sleeping?

A: Official regulatory documents do list sleep disorders as a possible adverse reaction. However, the exact frequency or likelihood of this occurrence is not specifically known or quantified in the product information.


Q: What happens if a person accidentally takes too much Korodin?

A: Official regulatory information states that no cases of overdose or poisoning symptoms have been reported when the medicine is used according to the instructions. The regulatory documents establish an absolute maximum single adult dose, which is specified in the official product labeling.


Q: Is Korodin safe for people who have sensitive skin or allergies?

A: The medicine is formally contraindicated if a person has a known allergy or hypersensitivity to the active ingredients or other components of the solution. Additionally, allergic skin reactions have been reported as a rare side effect in susceptible individuals.


Q: Is Korodin known to cause stomach upset or digestive problems?

A: Official lists of possible adverse reactions include general gastrointestinal complaints. While this means digestive issues are recognized, the frequency of these occurrences is not known, as they are not listed among the commonly reported side effects.


Q: Does Korodin have any known effects on kidney or liver function?

A: The official warnings require that the product’s high alcohol content must be considered by patients with an increased risk due to liver disease. There are no specific warnings or restrictions mentioned in the official profile concerning the product's effect on kidney function.


Q: Is it true that Korodin has been used in some countries for many decades?

A: Regulatory summaries and background reviews often note that the combination of D-camphor and hawthorn has been used in medical therapy for hypotension for many decades. This information provides historical context for the product’s longevity in circulation.


Q: Does Korodin interact with herbal supplements like St. John's Wort or ginseng?

A: Official regulatory documents state that no interactions are known with other medicinal products. This classification applies broadly to both prescription and non-prescription products, including other herbal remedies.


Q: What is the evidence regarding Korodin's effect on heart rate?

A: Clinical studies have included heart rate measurements as part of the overall assessment of circulatory function. Official documentation for the product's primary use focuses on general circulatory function. Studies have reported no known problems or consistent, significant effects on heart rate.


Q: Is the dosage form (drops) related to how quickly Korodin works?

A: The liquid drop form and method of administration (undiluted) are designed to facilitate absorption, which is key to the expected quick effect. The formulation is required because one of the main components is not water-soluble.


Q: Are there any religious or cultural restrictions on ingredients in Korodin?

A: The product contains 60 Vol.-% Alcohol in its formulation. The presence of a high ethanol content may be a factor for individuals who must observe religious or cultural restrictions on alcohol consumption.


Q: Can Korodin be used by individuals who have diabetes?

A: The official usage instructions specifically address administration for individuals with diabetes. They state that the drops should be placed on a piece of bread instead of sugar before ingestion, allowing for use in this population.


Q: Can Korodin interact with common cold or flu medications?

A: Official regulatory documents clearly state that no interactions are known with other medicinal products. This determination covers standard over-the-counter medicines, including those used for the common cold or flu.


Q: Is it necessary to take Korodin with a meal?

A: The official dosing recommendation specifically states that the drops can be taken independently of the meal. Patients are instructed to focus on the proper method of intake (undiluted on sugar or bread) rather than the timing around food consumption.

How should Korodin be stored and disposed of?

How to Store and Dispose of Korodin?

The storage and disposal instructions for Korodin Herz-Kreislauf-Tropfen are defined by the product's official regulatory labeling, focusing on stability and child safety.


Storage and Stability Requirements

The medicine does not require any special storage conditions, meaning it is stable at normal room temperature. The product must not be used after the expiry date printed on the carton and label. Once the bottle has been opened, the contents remain stable for a period of 6 months.

Safety and Disposal Mandates

It is mandatory to keep this medicine out of the sight and reach of children.

Unused or expired Korodin drops and any waste material must be disposed of according to local regulations. There are no special requirements classifying the drops as hazardous waste; disposal should align with local pharmacy or municipal guidelines for medicinal waste.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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