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Components:
Ketoprofen
Method of action:
Analgesic, Analgetic, Anti-Inflammatory, Antipyretic, Nonsteroidal Anti-Inflammatory, Pain Reliever, Reducing Aggregation Of Platelets, Topical Products For Joint And Muscular Pain
Medically reviewed by Fedorchenko Olga Valeryevna, Pharmacy-Provisor. Last updated on 2019.12.09

Pharmacodynamic properties

The information provided in Pharmacodynamic properties of Ketoprofeno Genfar is based on data of another medicine with exactly the same composition as the Ketoprofeno Genfar of the medicine (Ketoprofen). Be careful and be sure to specify the information on the section Pharmacodynamic properties in the instructions to the drug Ketoprofeno Genfar directly from the package or from the pharmacist at the pharmacy.
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Ketoprofen overall has the properties of a potent non-steroidal anti-inflammatory agent. It has the following pharmacological effects:

Anti-inflammatory

It inhibits the development of carageenan-induced abscesses in rats at 1mg/kg, UV radiation induced erythema in guinea pigs at 6mg/kg. It is also a potent inhibitor of PGE2 and PFG2PROPORTIONAL TO (8733) synthesis in guinea pig and human chopped lung preparations.

Analgesic

Ketoprofen effectively reduced visceral pain in mice caused by phenyl benzoquinone or by bradykinin following p.o. Administration at about 6 mg/kg.

Antipyretic

Ketoprofen (2 and 6 mg/kg) inhibited hyperthermia caused by s.c injection of brewer's yeast in rats and, at 1 mg/kg hyperthermia caused by i.v. administration of anticoagulant vaccine to rabbits.

Ketoprofen at 10 mg/kg i.v. did not affect the cardiovascular, respiratory, central nervous system or autonomic nervous systems.

Pharmacokinetic properties

The information provided in Pharmacokinetic properties of Ketoprofeno Genfar is based on data of another medicine with exactly the same composition as the Ketoprofeno Genfar of the medicine (Ketoprofen). Be careful and be sure to specify the information on the section Pharmacokinetic properties in the instructions to the drug Ketoprofeno Genfar directly from the package or from the pharmacist at the pharmacy.
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Ketoprofen is slowly but completely absorbed from Ketoprofeno Genfar capsules. Maximum plasma concentration occurs after 6 - 8 hours. It declines thereafter with a half-life of about 8 hours. There is no accumulation on continued daily dosing. Ketoprofen is very highly bound to plasma protein

Preclinical safety data

The information provided in Preclinical safety data of Ketoprofeno Genfar is based on data of another medicine with exactly the same composition as the Ketoprofeno Genfar of the medicine (Ketoprofen). Be careful and be sure to specify the information on the section Preclinical safety data in the instructions to the drug Ketoprofeno Genfar directly from the package or from the pharmacist at the pharmacy.
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No additional data of relevance to the prescriber.

Incompatibilities

The information provided in Incompatibilities of Ketoprofeno Genfar is based on data of another medicine with exactly the same composition as the Ketoprofeno Genfar of the medicine (Ketoprofen). Be careful and be sure to specify the information on the section Incompatibilities in the instructions to the drug Ketoprofeno Genfar directly from the package or from the pharmacist at the pharmacy.
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None stated

Special precautions for disposal and other handling

The information provided in Special precautions for disposal and other handling of Ketoprofeno Genfar is based on data of another medicine with exactly the same composition as the Ketoprofeno Genfar of the medicine (Ketoprofen). Be careful and be sure to specify the information on the section Special precautions for disposal and other handling in the instructions to the drug Ketoprofeno Genfar directly from the package or from the pharmacist at the pharmacy.
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None stated

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