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Infloc 2 % Pomada

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Infloc 2 % Pomada

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Medically reviewed

Rosario Oropesa

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

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Overview of Infloc 2 % Pomada

Property Description
Active ingredient Fusidic Acid (Ácido fusídico)
Form Ointment (Pomada), 2% concentration
Pharmacological class Topical Antibiotic / Anti-Bacterial Agent
Common use Control of localized skin infections
Origin Semisynthetic (derived from Fusidium coccineum)

What Type of Medicine is Infloc 2 % Pomada?

Infloc 2 % Pomada is a medication classified as a topical antibiotic or Anti-Bacterial Agent designated for external use, grouped among other antibiotics for skin use. The preparation is defined by its pharmaceutical format as an ointment (pomada), specifying a semi-solid, fatty vehicle designed for localized, cutaneous use. This medicine contains a single active ingredient and is clinically recognized for its efficacy against gram-positive bacteria, particularly Staphylococcus species.

Composition and Origin of the Active Ingredient (Fusidic Acid)

The sole active ingredient is Fusidic Acid (Ácido fusídico). This compound is classified as a steroidal antibiotic, a differentiating factor due to its unique chemical skeleton, although its function is strictly antibacterial, possessing no associated anti-inflammatory steroid effects. Its origin is semisynthetic, as it is derived from the natural metabolites of the fungus Fusidium coccineum and subsequently refined for pharmaceutical application. This formulation, containing the active ingredient blended into a stable, inert fatty base, is favored for its enhanced ability to ensure high tissue concentrations.

General Purpose of this Topical Anti-Bacterial Agent

The general therapeutic purpose of Infloc 2 % Pomada is to help the body control and resolve localized superficial bacterial infections that are susceptible to the active agent, such as minor impetigo or infected dermatitis. Its mechanism relies on interfering with the bacteria’s vital process of synthesizing proteins needed for their growth and replication. By arresting the multiplication of these harmful microorganisms, the action is primarily bacteriostatic, which is the fundamental mechanism employed to reduce the bacterial load and support the natural healing of the affected skin area.

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What side effects are possible with Infloc 2 % Pomada?

Possible Side Effects and Safety Information

The official safety profile for Infloc 2 % Pomada (Fusidic Acid ointment) is based on classifications from government regulatory documents, which group adverse reactions by frequency and affected system.

The most frequently reported side effects are localized and classified as Uncommon (occurring in ge 1/1,000 to <1/100 people). These primarily involve Skin and Subcutaneous Tissue Disorders and General Disorders at the Administration Site, which may include dermatitis, rash, pruritus (itching), erythema (redness), and a burning sensation or irritation at the application site.

Less frequently, reactions are classified as Rare (occurring in ge 1/10,000 to <1/1,000 people). These include clinically significant reactions such as Hypersensitivity (severe allergic reaction) and Angioedema (swelling under the skin), alongside urticaria, blister formation, and conjunctivitis. These rare events represent the most serious outcomes documented.

Due to the ointment’s topical route, systemic absorption of the active ingredient is considered negligible. This low absorption rate means that no adverse effects are anticipated for the paediatric population or during pregnancy and lactation, although application on the breast during breastfeeding should be avoided.

Regulatory documentation also highlights risks related to duration of exposure. Extended or recurrent use may increase the documented risk of developing antibiotic resistance and contact sensitisation. A key restriction noted in the labeling is a contraindication against use in individuals with known hypersensitivity to any component, and the instruction to avoid contact with the eyes when applying to the face.

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Overdose and Emergency Response

Due to its classification as a topical antibiotic, an overdose resulting from the standard or excessive application of Infloc 2 % Pomada is officially documented as unlikely to occur. Regulatory authorities state that the systemic absorption of the active ingredient, Fusidic Acid, through the skin is minimal, meaning there are no specific systemic signs or symptoms of overdose listed in regulatory information for this route of exposure.

The primary regulatory focus for overdose is the event of accidental ingestion (swallowing) of the ointment. Official labeling advises that systemic consequences from accidental oral intake are generally unlikely to cause harm, but notes that urgent medical attention may still be required. The main risk following ingestion is the potential for a severe reaction if a pre-existing hypersensitivity to the active substance or its components exists.

Immediate Actions Mandated by Regulators

If accidental ingestion of Infloc 2 % Pomada is suspected or confirmed, you must contact a doctor or Poison Control Centre immediately. This immediate help-seeking action is mandatory even if there are no immediate signs of discomfort.

A specific consideration exists for infants: the ingestion of a whole tube is a particular concern for a child aged less than 1 year and weighing le 10 kg and requires professional medical evaluation. Management of a suspected overdose is typically supportive and directed toward the alleviation of any symptoms.

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Therapeutic Uses of Infloc 2 % Pomada

What Infloc 2 % Pomada Treats: Main Uses and Benefits

Infloc 2 % Pomada is commonly used across therapeutic domains, including those relevant to bacterial skin infections. The active substance is used for non-severe, localized primary skin infections. This ointment is commonly used across conditions presenting with acute episodes of primary bacterial skin infection, such as Impetigo (school sores), Folliculitis, and localized boils. It is also applicable in situations where conditions like dermatitis or minor wounds develop a secondary bacterial infection.

The primary benefit involves supportive relief in conditions where bacterial activity is involved. It directly helps address pronounced manifestations like the redness, swelling, and purulent discharge seen in active skin infections. By assisting with symptom clusters that may become intense or disruptive, it offers symptomatic relief that may help patients cope more steadily with difficult episodes, and contributes to improved day-to-day comfort during symptomatic periods. This is generally applied when symptoms interfere with daily comfort.


Quick Fact: Relevance for Inflammatory States
Symptom Group: Symptoms related to inflammatory or irritative states.
Context: Commonly used when symptoms interfere with daily comfort.
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Eligibility and Restrictions for Use

Infloc 2 % Pomada is a topical antibiotic ointment whose active ingredient is fusidic acid (2%). It is indicated for treating a variety of localized skin infections caused by bacteria sensitive to fusidic acid, primarily Staphylococcus species.

Who Can Use Infloc 2 % Pomada?

This ointment is generally used by patients for the treatment of common bacterial skin infections, including:

  • Boils (furuncles)
  • Impetigo (a superficial skin infection)
  • Pyoderma
  • Abscesses
  • Folliculitis (inflammation of hair follicles)
  • Infected acne and wounds

Who Cannot Use Infloc 2 % Pomada?

This medication is contraindicated and should not be used by individuals with a known hypersensitivity or allergy to fusidic acid, the active substance, or to any of the excipients (inactive ingredients) in the ointment's formulation.

Patients should also consult a healthcare professional before use if the infection involves a large area of skin, is near the eyes, or if there is any doubt regarding the type of infection.

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What should I know about interactions with other medicines?

Interaction Scope

The official regulatory profile for Infloc 2 % Pomada is defined by the negligible systemic absorption of the active ingredient, Fusidic Acid, following topical application. This inherent pharmacokinetic characteristic prevents the active substance from reaching the plasma concentrations required to cause systemic drug-drug interactions. Consequently, regulatory documents do not list any specific medicinal product categories or individual medicines that interact with the ointment. The mechanistic basis for this is officially stated as the low systemic exposure.


Interaction Classifications (High-Level)

Interactions with systemically administered medicinal products are consistently classified as minimal by official regulatory authorities. This classification is directly tied to the topical route of administration. There are no known or documented interactions with food, alcohol, herbal products, or supplements that require timing separation or dietary restrictions. No formal contraindicated combinations or special population-specific notes regarding interaction severity are listed in the product information for this ointment.


Resulting Interaction Structure

Official regulatory statements confirm that no specific drug interaction studies have been performed for the topical formulation. Due to the lack of systemic exposure, no documented exposure-altering effects, such as changes in plasma concentrations (AUC/Cmax), have been identified. This status means no mandatory timing rules are required for co-administration with other medicines, and no interaction-related restrictions are listed.

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Mechanism of Action

How Infloc 2 % Pomada Works (Mechanism of Action)

The action of Infloc 2 % Pomada, containing Fusidic Acid, is purely mechanistic and focused on disrupting the core metabolic processes of susceptible bacteria.

Specific Arrest of Bacterial Protein Synthesis

The active ingredient specifically targets the bacterial 70S ribosome and the enzyme Elongation Factor G ( EF-G). Fusidic Acid functions as an inhibitor, binding to the ribosome and physically locking EF-G in place. This binding inhibits the translocation of genetic material ( mRNA) and the growing protein chain, thereby ceasing the manufacturing of all essential bacterial proteins.

Mechanistic Control of Microbial Proliferation

This cessation of protein synthesis inhibits the target bacteria from dividing or multiplying, establishing a state of bacteriostasis (growth arrest). This mechanism achieves the containment of the microbial population, which stabilizes the bacterial load and allows the host's physiological clearance mechanisms to proceed.

Biological Selectivity and Mechanistic Limitations

The drug exhibits high selective toxicity because the human 80S ribosome is structurally distinct. Conversely, the mechanism is biologically limited by bacterial resistance genes (e.g., fusB), which promote active drug displacement, and by membrane barriers in Gram-negative bacteria, which restrict drug access to the ribosomal target.

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Dosage and Administration Information

How to Use Infloc 2 % Pomada

This section describes the standard application and dosing regimen for Infloc 2 % Pomada (Fusidic Acid 2% Ointment). This information focuses solely on the manner and schedule of use and does not cover therapeutic claims or safety information.


Administration Guidelines

Feature Instruction
Route of Administration The medicine is strictly for cutaneous use (topical application) and is designated as external use only.
Application Regimen A small amount of the ointment should be applied to the affected area in a thin film.
Frequency For uncovered skin lesions, the preparation is typically applied three or four times daily. When an occlusive dressing or bandage is used, application frequency may be reduced to, for example, one or two times daily.
Treatment Duration The typical course of treatment is seven days. Treatment should not normally exceed 14 days to mitigate the potential for bacterial resistance.

Use Protocol

Infloc 2 % Pomada is manufactured as an ointment with a 2% concentration of Fusidic Acid. The application procedure is standardized for both adults and the paediatric population (children). Care must be taken to avoid contact with the eyes, especially during application to the face. The overall use protocol is defined by a consistent, short-term course of treatment that limits the total exposure duration. The variability in frequency is the key determinant of use, depending on whether or not a covering is used over the lesion.

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Recent Clinical Evidence

Research Evidence / Overview of Studies for Infloc 2 % Pomada

Research examining Infloc 2% Pomada focuses on different clinical situations where the product was studied. This research provides context regarding group patterns observed in the studies, but does not offer individual predictions. The evidence base generally involves studies that explored short-term symptom changes and often looked at episodic symptom patterns related to skin infections.


Evidence for Localized Impetigo and Other Infections

The core evidence for localized impetigo largely stems from Randomized Controlled Trials (RCTs) and systematic reviews. These studies monitored endpoints related to lesion change and bacterial presence in affected pediatric and adult populations. Comparative trials monitored measured changes when comparing the ointment to other topical and oral anti-bacterial agents. Findings describe patterns observed in the studies regarding outcomes related to physical discomfort.

For other superficial skin infections, such as secondary infected dermatoses, studies monitored overall clinical response and patient-reported outcomes describing perceived discomfort. Data show patterns observed in the studies regarding the healing time for susceptible infections. These trials often had sample sizes that were modest, and evidence quality varies across the mixed study populations.


Research Gaps and Uncertainty

The evidence base primarily reflects short-term data derived from studies that monitored measured changes over defined time intervals. Long-term effects, such as the durability of the initial cure or rates of infection recurrence, are not fully established by the available research. Data for certain groups, including older adults or those with complex chronic conditions, remain insufficient.

Inconsistent results in studies focusing on broader, secondary infections indicate that data are still emerging in these areas. Additionally, geographical variability in bacterial resistance patterns may introduce uncertainty regarding bacteriological outcomes. The research does not determine whether an individual will respond similarly, as findings describe group patterns, not personal outcomes.

Key Studies & References

  1. WHO ATC Classification: D06AX01 Other Antibiotics for Topical Use
  2. UK National Institute for Health and Care Excellence (NICE) Guidelines: Impetigo - antimicrobial prescribing
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Frequently Asked Questions (FAQ)

Common questions about Infloc 2 % Pomada (FAQ)

Q: What is Infloc 2 % Pomada and what is it used for?

Infloc 2 % Pomada is a topical medication that contains the active ingredient miconazole nitrate at a concentration of 2%.

Miconazole is an antifungal agent that works by interfering with the structure of the fungal cell wall, which inhibits the growth of the fungus.

It is primarily used to treat certain skin and nail infections caused by fungi, such as:

  • Athlete's foot (Tinea pedis)
  • Jock itch (Tinea cruris)
  • Ringworm (Tinea corporis)
  • Skin infections caused by Candida (e.g., in the diaper area or skin folds)

Q: How should I apply Infloc 2 % Pomada?

Before application, clean and dry the affected area thoroughly. This helps the medicine work better and prevents further spread of the infection.

Apply a thin layer of the pomada to the infected skin and the immediate surrounding area. Gently rub it in until it disappears.

  • How often: It is typically applied once or twice a day, or as directed by a healthcare professional.
  • Duration: The duration of treatment depends on the infection type and severity. Generally, treatment should continue for up to two to four weeks, even if symptoms improve earlier. Stopping too soon can cause the infection to return.
  • Hands: Wash your hands immediately after applying the pomada to avoid spreading the infection to other parts of your body or to other people.

Q: Can I use Infloc 2 % Pomada for vaginal yeast infections?

Infloc 2 % Pomada is formulated for external skin use and is used for treating fungal infections like athlete's foot and ringworm.

While the active ingredient, miconazole, is also used in products for vaginal yeast infections, this specific pomada formulation is not intended for internal or vaginal use. You should only use the specific product recommended by your healthcare provider for that area.


Q: What should I do if I miss an application?

If you miss an application of Infloc 2 % Pomada, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Consistency is important for effective treatment. Try to apply the pomada at the same time(s) each day.

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How should Infloc 2 % Pomada be stored and disposed of?

How to Store and Dispose of Infloc 2 % Pomada

Storage and disposal instructions for Infloc 2 % Pomada (Fusidic Acid 2% Ointment) are defined by regulatory documents to maintain product quality and safety.


Official Storage Requirements

Condition
Do not store above 25 C.
Do not refrigerate or freeze.
Keep the product out of the sight and reach of children.
Store in the original container, tightly closed, protected from light and moisture.
The ointment must be discarded 4 weeks after the tube is first opened.

Disposal Requirements

Official instructions state that the medicine should not be disposed of via wastewater or household waste. Unused or expired product must be disposed of in accordance with local requirements. Patients should consult their pharmacist for proper disposal methods.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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