Hicel

Intraocular

Adjunct in ophthalmic surgery

Adult: Administered intraocularly as a 2% soln.

Ophthalmic

Protection of the cornea during gonioscopy procedures

Adult: Apply up to 2.5% soln.

Ophthalmic

Dry eye

Adult: As 0.3-1% soln: Instil 1-2 drops in affected eye(s) as needed.

Methylcellulose (Hicel) is a Methylcellulose (Hicel)-forming laxative. Methylcellulose (Hicel) absorbs liquid in the intestines and makes a bulky, softer stool which is easier to pass.

Methylcellulose (Hicel) helps relieve constipation and to maintain regularity.

Hypromellose (Hicel) is used as a surgical aid in certain eye surgeries, such as cataract removal and lens implantation procedures. It helps maintain the shape of the eye during surgery as well as protect the tissues of the eye from damage due to surgical instruments.

Hypromellose (Hicel) is available only with your doctor's prescription.

Methylcellulose (Hicel) is a Methylcellulose (Hicel)-forming laxative that increases the amount of water in your stools to help make them softer and easier to pass.

Methylcellulose (Hicel) is used to treat constipation and to help maintain regular bowel movements.

Methylcellulose (Hicel) may also be used for purposes not listed in this medication guide.

Intraocular

Adjunct in ophthalmic surgery

Adult: Administered intraocularly as a 2% soln.

Ophthalmic

Protection of the cornea during gonioscopy procedures

Adult: Apply up to 2.5% soln.

Ophthalmic

Dry eye

Adult: As 0.3-1% soln: Instil 1-2 drops in affected eye(s) as needed.

Usual Adult Dose for Constipation

2 tablets (1000 mg) orally with 8 oz of liquid up to 6 times a day, or 1 heaping tablespoonful (19 g) of powder dissolved in 8 oz of cold water orally up to 3 times a day, or 1 heaping tablespoonful (10.2 g) of sugar-free powder dissolved in 8 oz of cold water orally up to 3 times a day.

Usual Pediatric Dose for Constipation

6 to 12 years:

1 tablet (500 mg) orally with 8 oz of liquid up to 6 times a day, or one-half tablespoonful (9.5 g) of powder dissolved in 8 oz of cold water orally once a day, or one-half tablespoonful (5.1 g) of sugar-free powder dissolved in 8 oz of cold water orally once a day. The mixture should be administered promptly, and drinking another glass of water is highly recommended.

>12 years:

oral tablet:

2 tablets (1000 mg) orally with 8 oz of liquid up to 6 times a day, or 1 heaping tablespoonful (19 g) of powder dissolved in 8 oz of cold water orally up to 3 times a day, or 1 heaping tablespoonful (10.2 g) of sugar-free powder dissolved in 8 oz of cold water orally up to 3 times a day.

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

No adjustment recommended

Precautions

Administer with at least an 8 ounce glass of water or other fluid. Taking this product without enough liquid may cause it to swell and block the esophagus possibly resulting in choking.

Methylcellulose (Hicel) should not be used in patients with difficulty swallowing.

Seek immediate medical attention if chest pain, vomiting, and/or difficulty swallowing or breathing occur after administration.

Do not take sugar-free product if on a phenylalanine-free diet.

Do not use for longer than 1 week unless directed by a physician.

Methylcellulose (Hicel) should generally not be used for a period of greater than one week, unless otherwise directed by a physician.

Methylcellulose (Hicel) should generally not be used if abdominal pain, nausea, or vomiting are present, unless otherwise directed by a physician.

Dialysis

No adjustment recommended

Other Comments

Continued use for 12 to 72 hours may be necessary for full benefit. Methylcellulose (Hicel) generally produces bowel movement in 12 to 72 hours.

See also:
What is the most important information I should know about Hypromellose (Hicel)?

In allergic patients who are hypersensitive to Hypromellose (Hicel)

See also:
What is the most important information I should know about Methylcellulose (Hicel)?

Hypersensitivity to the active substance or to any of the excipients.

Not for use with soft contact lenses.

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Do not use this medicine while wearing contact lenses. Ocular lubricant may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medicine before putting in your contact lenses.

Wash your hands before using the eye drops.

To apply the eye drops:

• Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.

• Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.

• Use only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops.

• Wait at least 10 minutes before using any other eye drops your doctor has prescribed.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.

To apply the ointment:

• Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the ointment tube with the tip pointing toward this pocket. Look up and away from the tip.

• Squeeze out a ribbon of ointment into the lower eyelid pocket without touching the tip of the tube to your eye. Blink your eye gently and then keep it closed for 1 or 2 minutes.

• Use a tissue to wipe excess ointment from your eyelashes.

• After opening your eyes, you may have blurred vision for a short time. Avoid driving or doing anything that requires you to be able to see clearly.

Do not touch the tip of the eye dropper or ointment tube. Do not place the tip directly on your eye. A contaminated dropper or tube tip can infect your eye, which could lead to serious vision problems.

Call your doctor if your symptoms do not improve, or if they get worse while using ocular lubricant.

Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle or tube tightly closed when not in use.

Use Methylcellulose (Hicel) eye drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• To use Methylcellulose (Hicel) eye drops, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
• To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
• Remove contact lenses before using Methylcellulose (Hicel) eye drops.
• Do not use Methylcellulose (Hicel) eye drops if it becomes cloudy or changes color.
• If you miss a dose of Methylcellulose (Hicel) eye drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Methylcellulose (Hicel) eye drops.

This medication is used to relieve dry, irritated eyes. Common causes for dry eyes include wind, sun, heating/air conditioning, computer use/reading, and certain medications.

This product may contain 1 or more of the following ingredients: carboxymethylcellulose, dextran, glycerin, Hypromellose (Hicel), polyethylene glycol 400 (PEG 400), polysorbate, polyvinyl alcohol, povidone, or propylene glycol, among others.

Eye lubricants keep the eye moist, help to protect the eye from injury and infection, and decrease symptoms of dry eyes such as burning, itching, and feeling as if something is in the eye.

How to use Hypromellose (Hicel) ophthalmic

Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist. Do not use a solution that has changed color or is cloudy. Certain brands (containing glycerin with polysorbates, among other ingredients) may have a milky appearance. This is okay as long as the solution does not change color. Some eye drops need to be shaken before use. Check the label to see if you should shake your product before using.

Usually, drops may be used as often as needed. Ointments are usually used 1 to 2 times daily as needed. If using an ointment once a day, it may be best to use it at bedtime.

To apply eye ointment/drops/gels: Wash hands first. To avoid contamination, be careful not to touch the dropper or top of the ointment tube or let it touch your eye. Always replace the cap tightly after each use. Tilt your head back, look up, and pull down the lower eyelid to make a pouch. For drops/gels, place the dropper directly over the eye and squeeze out 1 or 2 drops as needed. Look down and gently close your eye for 1 or 2 minutes. Place one finger at the corner of the eye near the nose and apply gentle pressure. This will prevent the medication from draining away from the eye. For an ointment, hold the tube directly over the eye and gently squeeze a small strip (one-fourth of an inch or roughly 6 millimeters) of ointment into the pouch. Release the eyelid, close the eye, and slowly roll your eye in all directions to spread the medication. Blot away any extra ointment from around the eye with a clean tissue.

If you are also using another kind of eye medication (e.g., drops or ointments), wait at least 5 minutes before applying other medications. Use eye drops before eye ointments to allow the eye drops to enter the eye.

If you wear contact lenses, remove them before using most kinds of eye lubricants. Ask your doctor or pharmacist when you may replace your contact lenses. There are a few types of eye lubricants (some that contain polysorbates) that can be used while wearing contact lenses. Check the package to see if you can wear your contact lenses while using your product.

Tell your doctor if your condition persists or worsens after 3 days.

This medication is used to relieve dry, irritated eyes. Common causes for dry eyes include wind, sun, heating/air conditioning, computer use/reading, and certain medications.

This product may contain 1 or more of the following ingredients: carboxymethylcellulose, dextran, glycerin, Methylcellulose (Hicel), polyethylene glycol 400 (PEG 400), polysorbate, polyvinyl alcohol, povidone, or propylene glycol, among others.

Eye lubricants keep the eye moist, help to protect the eye from injury and infection, and decrease symptoms of dry eyes such as burning, itching, and feeling as if something is in the eye.

How to use Methylcellulose (Hicel) ophthalmic

Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist. Do not use a solution that has changed color or is cloudy. Certain brands (containing glycerin with polysorbates, among other ingredients) may have a milky appearance. This is okay as long as the solution does not change color. Some eye drops need to be shaken before use. Check the label to see if you should shake your product before using.

Usually, drops may be used as often as needed. Ointments are usually used 1 to 2 times daily as needed. If using an ointment once a day, it may be best to use it at bedtime.

To apply eye ointment/drops/gels: Wash hands first. To avoid contamination, be careful not to touch the dropper or top of the ointment tube or let it touch your eye. Always replace the cap tightly after each use. Tilt your head back, look up, and pull down the lower eyelid to make a pouch. For drops/gels, place the dropper directly over the eye and squeeze out 1 or 2 drops as needed. Look down and gently close your eye for 1 or 2 minutes. Place one finger at the corner of the eye near the nose and apply gentle pressure. This will prevent the medication from draining away from the eye. For an ointment, hold the tube directly over the eye and gently squeeze a small strip (one-fourth of an inch or roughly 6 millimeters) of ointment into the pouch. Release the eyelid, close the eye, and slowly roll your eye in all directions to spread the medication. Blot away any extra ointment from around the eye with a clean tissue.

If you are also using another kind of eye medication (e.g., drops or ointments), wait at least 5 minutes before applying other medications. Use eye drops before eye ointments to allow the eye drops to enter the eye.

If you wear contact lenses, remove them before using most kinds of eye lubricants. Ask your doctor or pharmacist when you may replace your contact lenses. There are a few types of eye lubricants (some that contain polysorbates) that can be used while wearing contact lenses. Check the package to see if you can wear your contact lenses while using your product.

Tell your doctor if your condition persists or worsens after 3 days.

See also:
What other drugs will affect Hypromellose (Hicel)?

If you are using this product under your doctor's direction, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using this product, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: other eye medications.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

See also:
What other drugs will affect Methylcellulose (Hicel)?

Methylcellulose (Hicel) can interact with other medications. Before taking Methylcellulose (Hicel), talk to your doctor if you are taking any prescription or over-the-counter medicines. You may not be able to take Methylcellulose (Hicel), or you may require a dosage adjustment or special monitoring if you are taking any other medicines.

See also:
What are the possible side effects of Hypromellose (Hicel)?

Vision may be temporarily blurred when this product is first used. Also, minor burning/stinging/irritation may temporarily occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: eye pain, change in vision, continued eye redness/irritation.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

See also:
What are the possible side effects of Methylcellulose (Hicel)?

Applies to Methylcellulose (Hicel): powder, powder packets, tablets

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abdominal fullness.

Seek medical attention right away if any of these SEVERE side effects occur while taking Methylcellulose (Hicel) (the active ingredient contained in Methylcellulose (Hicel))

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; difficulty swallowing; nausea; rectal bleeding; stomach pain; vomiting.