Components:
Medically reviewed by Oliinyk Elizabeth Ivanovna, PharmD. Last updated on 19.03.2022
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Top 20 medicines with the same components:
Intravenous
Disseminated malignant melanoma
Adult: Initially, 100 mg/m2 BSA wkly for 3 wk to induce remission.
Maintenance: To be started 4-5 wk after induction course, 100 mg/m2 BSA every 3 wk if blood counts permit. Dose to be given via IV infusion over 1 hr. May also be given intra-arterially.
Intravenous
Disseminated malignant melanoma
Adult: Initially, 100 mg/m2 BSA wkly for 3 wk to induce remission.
Maintenance: To be started 4-5 wk after induction course, 100 mg/m2 BSA every 3 wk if blood counts permit. Dose to be given via IV infusion over 1 hr. May also be given intra-arterially.
Pregnancy; lactation; child.
Dacarbazine.
Bone-marrow suppression and haematological toxicity (possibly delayed); GI disturbances; injection-site phloebitis, fever, pruritus, neurological and biochemical disturbances; transient rise in blood urea; hepatic enzymes and bilirubin elevation.