Feroglobin Capsules

Copper (Feroglobin Capsules) 0.4 mg/mL (Cupric Chloride Injection, USP) is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN). Administration helps to maintain Copper (Feroglobin Capsules) serum levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.

Folic Acid (Feroglobin Capsules) is used in the treatment and prevention of the folate deficiency state. It does not correct folate deficiency due to dihydrofolate reductase inhibitors. Folic Acid (Feroglobin Capsules) is also used in women of child-bearing potential and pregnant women to protect against neural tube defects in their offspring. It is also used for the treatment of folate-deficient megaloblastic anaemia, chronic haemolytic states such as thalassaemia major or sickle-cell anaemia.

Film-Coated Tablet: Treatment of Iron (Feroglobin Capsules) deficiency. Prevention of Iron (Feroglobin Capsules) deficiency during pregnancy.

Syrup: All cases of Iron (Feroglobin Capsules) deficiency and Iron (Feroglobin Capsules) deficiency anaemia.

Drops: General: Hypochromic or masked Iron (Feroglobin Capsules) deficiency anaemias. General weakness. Convalescence. Blood losses. Tropical microcytic anaemia. Anaemias due to infections. For maintenance therapy in pernicious anaemia. As an adjuvant in treating chronically ill or undernourished patients.

Women: Iron (Feroglobin Capsules) deficiency due to menstruation. During and after pregnancy and lactation. Menorrhagia.

Children: All types of hypochromic anaemias and masked Iron (Feroglobin Capsules) deficiencies. Inappetence. Retarded growth. Weakness. Unsound dietary habits. To speed up restoration of depleted Iron (Feroglobin Capsules) reserves.

Pernicious anaemia, peripheral neuritis especially diabetic and alcoholic polyneuritis, trigeminal neuritis, vomiting of pregnancy, Vitamin B (Feroglobin Capsules) complex deficiency, anorexia, agranulocytosis, radiation sickness, coeliac and idiopathic, steatorrhoea which are usually accompanied by malabsorption of Vitamin B (Feroglobin Capsules) 12 and during administration of broad-spectrum antibiotics.

Patients with deficiency of B-complex vitamins, vitamin C and Zinc (Feroglobin Capsules) or where supplementation of these vitamins and Zinc (Feroglobin Capsules) can be beneficial. Such patients and conditions include: Patients who are on prolonged antibiotic therapy; those who are suffering from infection, injuries, burns, fever, illness; patients with diarrhoea and GI disorders; patients who have undergone surgical operations; patients on diet restrictions eg, in diabetes, anorexia and alcoholism and in elderly persons; pregnant and lactating women due to increased nutritional needs.

Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are usually available in the foods that you eat. Folic Acid (Feroglobin Capsules) (vitamin B 9) is necessary for strong blood.

Lack of Folic Acid (Feroglobin Capsules) may lead to anemia (weak blood). Your health care professional may treat this by prescribing Folic Acid (Feroglobin Capsules) for you.

Some conditions may increase your need for Folic Acid (Feroglobin Capsules). These include:

• Alcoholism
• Anemia, hemolytic
• Diarrhea (continuing)
• Fever (prolonged)
• Hemodialysis
• Illness (prolonged)
• Intestinal diseases
• Liver disease
• Stress (continuing)
• Surgical removal of stomach

In addition, infants smaller than normal, breast-fed infants, or those receiving unfortified formulas (such as evaporated milk or goat's milk) may need additional Folic Acid (Feroglobin Capsules).

Increased need for Folic Acid (Feroglobin Capsules) should be determined by your health care professional.

Some studies have found that Folic Acid (Feroglobin Capsules) taken by women before they become pregnant and during early pregnancy may reduce the chances of certain birth defects (neural tube defects).

Claims that Folic Acid (Feroglobin Capsules) and other B vitamins are effective for preventing mental problems have not been proven. Many of these treatments involve large and expensive amounts of vitamins.

Injectable Folic Acid (Feroglobin Capsules) is given by or under the direction of your health care professional. Another form of Folic Acid (Feroglobin Capsules) is available without a prescription.

Supplementing Iron (Feroglobin Capsules) in the diet and treating or preventing low levels of Iron (Feroglobin Capsules) in the blood. It may also be used for other conditions as determined by your doctor.

Iron (Feroglobin Capsules) suspension is a mineral. It works by providing Iron (Feroglobin Capsules) to the body.

Zinc (Feroglobin Capsules) is a naturally occurring mineral. Zinc (Feroglobin Capsules) is important for growth and for the development and health of body tissues.

Zinc (Feroglobin Capsules) sulfate is used to treat and to prevent Zinc (Feroglobin Capsules) deficiency.

Zinc (Feroglobin Capsules) sulfate may also be used for purposes not listed in this medication guide.

Copper (Feroglobin Capsules) 0.4 mg/mL (Cupric Chloride Injection, USP) contains 0.4 mg Copper (Feroglobin Capsules)/mL and is administered intravenously only after dilution. The additive should be diluted in a volume of fluid not less than 100 mL. For the adult receiving TPN, the suggested additive dosage is 0.5 to 1.5 mg Copper (Feroglobin Capsules)/day (1.25 to 3.75 mL/day). For pediatric patients, the suggested additive dosage is 20 mcg Copper (Feroglobin Capsules)/kg/day (0.05 mL/kg/day). Infants weighing less than 1500 gm may have increased requirements because of their low body reserves and increased requirements for growth.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

Usual Adult Dose for Megaloblastic Anemia

1 mg orally, intramuscularly, subcutaneously or IV once a day. May continue until clinical symptoms of folate deficiency and the hematological profile have normalized.

Usual Adult Dose for Folic Acid (Feroglobin Capsules) Deficiency

400 to 800 mcg orally, intramuscularly, subcutaneously or IV once a day.

Women of childbearing age, pregnant, and lactating women: 800 mcg orally, intramuscularly, subcutaneously or IV once a day.

Usual Pediatric Dose for Folic Acid (Feroglobin Capsules) Deficiency

Infant:

0.1 mg orally, intramuscularly, subcutaneously or IV once a day.

Child:

Less than 4 years: up to 0.3 mg orally, intramuscularly, subcutaneously or IV once a day.

4 years or older: 0.4 mg orally, intramuscularly, subcutaneously or IV once a day.

Usual Pediatric Dose for Vitamin/Mineral Supplementation

Recommended daily allowance (RDA):

Premature neonates: 50 mcg/day (15 mcg/kg/day).

Full-term neonates and infants 1 to 6 months: 25 to 35 mcg/day.

Children:

1 to 3 years: 150 mcg/day.

4 to 8 years: 200 mcg/day.

9 to 13 years: 300 mcg/day.

14 years and older: 400 mcg/day.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Rarely, a dosage of 2 mg/day may be required, particularly in patients with malabsorption, alcoholism, chronic hemolysis, chronic exfoliative skin disease or who are on concomitant anticonvulsant therapy.

Dialysis

Folic Acid (Feroglobin Capsules) is removed by both hemodialysis and peritoneal dialysis. The amount removed varies with type equipment used.

Because folate may accumulate in patients with end-stage renal disease, side effects may be more likely in this patient who is undergoing dialysis. Once this patient's body stores of folate are replete, three times a week dosing may be just as beneficial as once daily dosing but should portend a lower risk of side effects.

Other Comments

The recommended daily allowance of Folic Acid (Feroglobin Capsules) for adult males and females ranges from 150 to 200 and 150 to 180 mcg/day, respectively.

There is a potential danger in administering Folic Acid (Feroglobin Capsules) to patients with undiagnosed anemia, since Folic Acid (Feroglobin Capsules) may obscure the diagnosis of pernicious anemia by alleviating the hematologic manifestations of the disease while allowing the neurologic complications to progress.

Severe megaloblastic anemia may require therapy for 4 to 5 weeks. Once stabilized, if dietary intake is inadequate, maintenance therapy can be started.

Film-Coated Tablet: Treatment of Iron (Feroglobin Capsules) Deficiency with Reduced Number of Red Blood Cells in Adults and Children over 12 Years: 1 to 3 tablets once daily or divided into separate doses for about 3 to 5 months.

After normalisation of the red blood pigment (haemoglobin) value, continue with 1 tablet once daily for several weeks. This will replenish the Iron (Feroglobin Capsules) stores.

Treatment of Iron (Feroglobin Capsules) Deficiency with Reduced Number of Red Blood Cells in Pregnancy: 2 to 3 tablets once daily or divided into separate doses.

After normalisation of the red blood pigment value, continue with 1 tablet once daily until, at least, the end of pregnancy. This will replenish the Iron (Feroglobin Capsules) stores and provide the increased amount of Iron (Feroglobin Capsules) required during pregnancy.

Treatment of Iron (Feroglobin Capsules) Deficiency with Normal Number of Red Blood Cells in Adults, Pregnancy, and Children over 12 years, and Prevention of Iron (Feroglobin Capsules) Deficiency in Pregnancy: 1 tablet once daily for 1 to 2 months.

Syrup:

Children: 5 mL 1 to 2 times daily before meals.

Infants: Begin with 2.5 mL daily and gradually increase to 5 mL daily.

Drops: Adults: 20 drops 2 to 3 times daily during or after a meal.

Children: 20 drops 1 to 2 times daily during or after a meal.

Infants: Begin with 6 drops daily and gradually increase to 20 drops daily.

Iron (Feroglobin Capsules) may be mixed with fruit, vegetable juices or other liquids if desired.

Best results are obtained by adequate dosage and regular administration. It is recommended that the therapy in conformity to the degree of Iron (Feroglobin Capsules) deficiency should be continued for at least 1 to 2 months.

Administration: Take Iron (Feroglobin Capsules) during or immediately after meal.

Duration of use depends upon the degree of Iron (Feroglobin Capsules) deficiency.

Do not discontinue sooner than recommended as this may reduce the success of therapy.

Initially 3ml i.m daily. Subsequently 2-3 times/week.

Zinc (Feroglobin Capsules) 1 mg/mL (Zinc (Feroglobin Capsules) Chloride Injection, USP) contains 1 mg Zinc (Feroglobin Capsules)/mL and is administered intravenously only after dilution. The additive should be diluted prior to administration in a volume of fluid not less than 100 mL. For the metabolically stable adult receiving TPN, the suggested intravenous dosage is 2.5 to 4 mg Zinc (Feroglobin Capsules)/day (2.5 to 4 mL/day). An additional 2 mg Zinc (Feroglobin Capsules)/day (2 mL/day) is suggested for acute catabolic states. For the stable adult with fluid loss from the small bowel, an additional 12.2 mg Zinc (Feroglobin Capsules)/liter of small bowel fluid lost (12.2 mL/liter of small bowel fluid lost), or an additional 17.1 mg Zinc (Feroglobin Capsules)/kg of stool or ileostomy output (17.1 mL/kg of stool or ileostomy output) is recommended. Frequent monitoring of Zinc (Feroglobin Capsules) blood levels is suggested for patients receiving more than the usual maintenance dosage level of Zinc (Feroglobin Capsules).

For full term infants and children up to 5 years of age, 100 mcg Zinc (Feroglobin Capsules)/kg/day

(0.1 mL/kg/day) is recommended. For premature infants (birth weight less than 1500 g) up to 3 kg in body weight, 300 mcg Zinc (Feroglobin Capsules)/kg/day (0.3 mL/kg/day) is suggested.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS.

How supplied

Zinc (Feroglobin Capsules) 1 mg/mL (Zinc (Feroglobin Capsules) Chloride Injection, USP) is supplied in 10 mL Plastic Vials (List No. 4090).

Store at 20 to 25°C (68 to 77°F).

HOSPIRA, INC., LAKE FOREST, IL 60045 USA. Revised: October, 2004

Pregnancy or suspected malignant genital tumor of its existence, acute inflammation, subacute or chronic genital tract, congenital or acquired anatomic abnormalities of the uterus and cervix, endometriosis, malposition and malsituaciones accused the uterus, uterine hypoplasia, genital bleeding of unknown etiology blood clotting disorders, Wilson’s disease, allergy to Copper (Feroglobin Capsules).

See also:
What is the most important information I should know about Folic Acid (Feroglobin Capsules)?

Because it may mask the hematologic abnormalities while neurological damage progresses, Folic Acid (Feroglobin Capsules) should not be used in the therapy of patients with vitamin B12 deficiency of any cause, unless there is associated folate deficiency. The Folic Acid (Feroglobin Capsules) content of one tablet a day however, is unlikely to mask pernicious anemia should this condition be present. Also, pregnancy during pernicious anemia is very rare.

See also:
What is the most important information I should know about Iron (Feroglobin Capsules)?

All cases of Iron (Feroglobin Capsules) overload and disturbances in utilization of Iron (Feroglobin Capsules).

Film-Coated Tablet: Allergy to Iron (Feroglobin Capsules) (III)-hydroxide polymaltose complex or any of the other ingredients of Iron (Feroglobin Capsules).

An Iron (Feroglobin Capsules) overload in the body.

Disturbed use of Iron (Feroglobin Capsules) by the body.

Reduced number of red blood cells (anaemia), not caused by Iron (Feroglobin Capsules) deficiency, such as due to increased red blood cell breakdown, vitamin B₁₂ deficiency.

Due to its benzyl alcohol content, doxapram injection is contraindicated in neonates.

Vitamin B (Feroglobin Capsules) should not be used in patients with epilepsy or other convulsive disorders.

Vitamin B (Feroglobin Capsules) is contraindicated in patients with mechanical disorders of ventilation such as mechanical obstruction, muscle paresis, flail chest, pneumothorax, acute bronchial asthma, pulmonary fibrosis or other conditions resulting in restriction of chest wall, muscles of respiration or alveolar expansion.

Vitamin B (Feroglobin Capsules) is contraindicated in patients with evidence of head injury or cerebral vascular accident and in those with significant cardiovascular impairment, severe hypertension, or known hypersensitivity to the drug or any of the injection components.

See also:
What is the most important information I should know about Zinc (Feroglobin Capsules)?

Hypersensitivity to any of the ingredients of Zinc (Feroglobin Capsules).

Use Folic Acid (Feroglobin Capsules) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Folic Acid (Feroglobin Capsules) may be administered as an injection by your health care professional.
• If you are using Folic Acid (Feroglobin Capsules) at home, carefully follow the injection procedures taught to you by your health care provider. If the medicine contains particles, is discolored, or if the vial is cracked or damaged in any way, do not use it.
• Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when full.
• If you miss a dose of Folic Acid (Feroglobin Capsules), use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Folic Acid (Feroglobin Capsules).

Use Iron (Feroglobin Capsules) suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Iron (Feroglobin Capsules) suspension is absorbed better on an empty stomach but may be taken with food if it upsets your stomach. Some foods (eg, eggs, whole grain breads, cereal, dairy products, coffee, tea) may decrease the amount of Iron (Feroglobin Capsules) absorbed by your body. Talk with your doctor about the best way to take Iron (Feroglobin Capsules) suspension with food if it upsets your stomach.
• Shake well before using.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• Take Iron (Feroglobin Capsules) suspension with a full glass (8 oz [240 mL]) of water.
• Do not lie down for 30 minutes after taking Iron (Feroglobin Capsules) suspension.
• If you take an antacid, a bisphosphonate (eg, alendronate), cefdinir, eltrombopag, methyldopa, penicillamine, a quinolone antibiotic (eg, ciprofloxacin), or a tetracycline (eg, minocycline), ask your doctor or pharmacist how to take it with Iron (Feroglobin Capsules) suspension.
• If you miss a dose of Iron (Feroglobin Capsules) suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Iron (Feroglobin Capsules) suspension.

Use: Labeled Indications

Trace element added to parenteral nutrition (PN) to prevent Copper (Feroglobin Capsules) deficiency; orally as a dietary supplement

Folic Acid (Feroglobin Capsules) is the man-made form of folate. Folate is a B-vitamin naturally found in some foods. It is needed to form healthy cells, especially red blood cells.

Folic Acid (Feroglobin Capsules) supplements may come in different forms (such as L-methylfolate, levomefolate, methyltetrahydrofolate). They are used to treat or prevent low folate levels. Low folate levels can lead to certain types of anemia. Conditions that can cause low folate levels include poor diet, pregnancy, alcoholism, liver disease, certain stomach/intestinal problems, kidney dialysis, among others. Women of childbearing age should receive adequate amounts of Folic Acid (Feroglobin Capsules) either through their diet or supplements to prevent infant spinal cord birth defects.

How to use Folic Acid (Feroglobin Capsules)

Take this product by mouth with or without food as directed by your doctor, usually once daily. If you are taking the over-the-counter product, follow all directions on the product package. If you have any questions, ask your doctor or pharmacist.

Dosage is based on your medical condition and response to treatment. Do not increase your dose or take this product more often than directed.

Take this product regularly to get the most benefit from it. To help you remember, take it at the same time each day. Follow the diet plan recommended by your doctor or dietician. See also Notes section.

If your condition persists or worsens, or if you think you may have a serious medical problem, get medical help right away.

This product is a combination of B vitamins used to treat or prevent vitamin deficiency due to poor diet, certain illnesses, alcoholism, or during pregnancy. Vitamins are important building blocks of the body and help keep you in good health. B vitamins include thiamine, riboflavin, niacin/niacinamide, vitamin B6, vitamin B12, Vitamin B (Feroglobin Capsules), and pantothenic acid.

Some brands of B vitamins also contain ingredients such as vitamin C, vitamin E, biotin, or zinc. Consult your doctor or pharmacist if you have questions about the ingredients in your brand.

How to use Vitamin B (Feroglobin Capsules)

Take this medication by mouth, usually once daily or as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

If you are taking a brand that contains vitamin C, take this medication by mouth with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise.

If you are taking chewable tablets, chew the tablet thoroughly before swallowing.

If you are taking extended-release capsules, swallow them whole. Do not crush or chew extended-release capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

If you are taking a liquid product, use a medication-measuring device to carefully measure the dose. Do not use a household spoon. Some liquid products need to be shaken before each dose. Some products that contain vitamin B12 need to be placed under the tongue and held there before swallowing. Follow label directions carefully to get the most benefit.

Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day.

Ascorbic Acid: Copper (Feroglobin Capsules) may decrease the serum concentration of Ascorbic Acid. Management: To minimize the risk for ascorbic acid degradation, add multivitamin product to TPN solution immediately prior to infusion or administer multivitamin and Copper (Feroglobin Capsules) in separate containers. Consider therapy modification

See also:
What other drugs will affect Folic Acid (Feroglobin Capsules)?

Medications that interfere with your bodys ability to use folate may also increase the need for this vitamin. Medications can interfere with folate utilization, including: anticonvulsant medications (such as phenytoin, and primidone) metformin (sometimes prescribed to control blood sugar in type 2 diabetes) sulfasalazine (used to control inflammation associated with Crohns disease and ulcerative colitis) triamterene (a diuretic) Methotrexate There has been concern about the interaction between vitamin B12 and Folic Acid (Feroglobin Capsules). Folic Acid (Feroglobin Capsules) supplements can correct the anemia associated with vitamin B12 deficiency. Unfortunately, Folic Acid (Feroglobin Capsules) will not correct changes in the nervous system that result from vitamin B12 deficiency. Permanent nerve damage could theoretically occur if vitamin B12 deficiency is not treated. Therefore, intake of supplemental Folic Acid (Feroglobin Capsules) should not exceed 1000 micrograms (g, sometimes mcg) per day to prevent Folic Acid (Feroglobin Capsules) from masking symptoms of vitamin B12 deficiency. It is important for older adults to be aware of the relationship between Folic Acid (Feroglobin Capsules) and vitamin B12 because they are at greater risk of having a vitamin B12 deficiency. If you are 50 years of age or older, ask your physician to check your B12 status before you take a supplement that contains Folic Acid (Feroglobin Capsules).

Drug interactions were not noted and were not studied in clinical studies.

Feridex I.V. (ferumoxides injectable solution) administration provides elemental Iron (Feroglobin Capsules). In patients who are receiving supplemental Iron (Feroglobin Capsules) orally or parenterally, the dose of supplemental Iron (Feroglobin Capsules) may need to be decreased.

The effect of concomitant parenteral Iron (Feroglobin Capsules) on Feridex I.V. dosing is not known.

Laboratory Test Findings

Serum Iron (Feroglobin Capsules) levels may be above the normal range following Feridex I.V. (ferumoxides injectable solution) administration. Transient increases in serum Iron (Feroglobin Capsules) of 15–100% of baseline were observed 18 to 24 hours after Feridex I.V. (ferumoxides injectable solution) administration, and returned to normal in most patients by 7 days after administration. Increases in serum ferritin levels were seen 1 to 7 days after administration.

In a Phase 1 study in normal subjects, PTT was statistically significantly increased; however, all values were within the normal range and no subjects had a more than 40% increase from baseline. In clinical trials of patients who had baseline hematologic abnormalities associated with underlying liver disease, an effect of Feridex I.V. (ferumoxides injectable solution) on platelet or PTT was not demonstrated. In patients with low hematocrit and hemoglobin, over a period of 48 hours to 7 days after Feridex I.V. (ferumoxides injectable solution), the serum Iron (Feroglobin Capsules), the hematocrit and hemoglobin levels increase slightly.

If you are taking this product under your doctor's direction, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not stop, start, or change the dosage of any medicine before checking with them first.

Before using this product, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: altretamine, cisplatin, certain antibiotics (e.g., chloramphenicol), certain anti-seizure drugs (e.g., phenytoin), levodopa, other vitamin/nutritional supplements.

This product may interfere with certain laboratory tests (e.g., urobilinogen, intrinsic factor antibodies), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this product.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

See also:
What other drugs will affect Zinc (Feroglobin Capsules)?

Pyridoxine reduces the effects of levodopa (but this does not occur if a dopa decarboxylase is also given); decreases serum concentrations of phenobarbitone. Concurrent administration of drugs eg, isoniazid, penicillamine and oral contraceptives increase the requirement for pyridoxine.

Absorption of cyanocobalamin from the GIT may be reduced by neomycin, aminosalicylic acid, histamine H₂-receptor antagonists and colchicine. Serum concentrations may be decreased by concurrent administration of oral contraceptives. Many of these interactions are unlikely to be of clinical significance but should be taken into account when performing assays for blood concentrations.

Parenteral chloramphenicol may attenuate the effect of vitamin B12 in anaemia.

Folate deficiency states may be produced by a number of drugs including antiepileptics, oral contraceptives, antituberculous drugs, alcohol and Zinc (Feroglobin Capsules) antagonists eg, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides; Zinc (Feroglobin Capsules) may decrease serum-phenytoin concentrations.

There may be an increased risk of myopathy or rhabdomyolysis when nicotinic acid is used concurrently with statins. Nicotinamide may increase the requirements for insulin or oral hypoglycaemics.

Ascorbic acid may increase the absorption of iron-deficiency states.

Ascorbic acid is often given in addition to desferrioxamine to patients with iron overload (thalassemia) to achieve better iron excretion. However, early on in treatment when there is excess tissue iron, there is some evidence that ascorbic acid may worsen the iron toxicity, particularly to the heart. Thus, ascorbic acid should not be given for the first month after starting desferrioxamine treatment.

The absorption of Zinc (Feroglobin Capsules) may be reduced by iron supplements, penicillamine, phosphorus-containing preparations and tetracyclines. Zinc (Feroglobin Capsules) supplements reduce the absorption of Zinc (Feroglobin Capsules), ciprofloxacin, iron, norfloxacin, penicillamine and tetracyclines.

Adverse Reactions

Generally well tolerated; excessive Copper (Feroglobin Capsules) levels may result in the following adverse effect.

Hepatic: Hepatic insufficiency (including hepatic necrosis)

See also:
What are the possible side effects of Folic Acid (Feroglobin Capsules)?

Allergic sensitization has been reported following both oral and parenteral administration of Folic Acid (Feroglobin Capsules).

Folic Acid (Feroglobin Capsules) is relatively nontoxic in man. Rare instances of allergic responses to Folic Acid (Feroglobin Capsules) preparations have been reported and have included erythema, skin rash, itching, general malaise, and respiratory difficulty due to bronchospasm. One patient experienced symptoms suggesting anaphylaxis following injection of the drug. Gastrointestinal side effects, including anorexia, nausea, abdominal distention, flatulence, and a bitter or bad taste, have been reported in patients receiving 15 mg Folic Acid (Feroglobin Capsules) daily for 1 month. Other side effects reported in patients receiving 15 mg daily include altered sleep patterns, difficulty in concentrating, irritability, overactivity, excitement, mental depression, confusion, and impaired judgment. Decreased vitamin B12 serum levels may occur in patients receiving prolonged Folic Acid (Feroglobin Capsules) therapy.

In an uncontrolled study, orally administered Folic Acid (Feroglobin Capsules) was reported to increase the incidence of seizures in some epileptic patients receiving phenobarbital, primidone, or diphenylhydantoin. Another investigator reported decreased diphenylhydantoin serum levels in folate-deficient patients receiving diphenylhydantoin who were treated with 5 mg or 15 mg of Folic Acid (Feroglobin Capsules) daily.

CALL YOUR DOCTOR FOR MEDICAL ADVICE ABOUT SIDE EFFECTS. YOU MAY REPORT SIDE EFFECTS TO THE FDA AT 1-800-FDA-1088 OR LEADING PHARMA, LLC AT 844-740-7500.

See also:
What are the possible side effects of Iron (Feroglobin Capsules)?

Applies to carbonyl Iron (Feroglobin Capsules): suspension

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; darkened or green stools; diarrhea; loss of appetite; nausea; stomach cramps, pain, or upset; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur while taking carbonyl Iron (Feroglobin Capsules):

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or tarry stools; blood or streaks of blood in the stool; fever; severe or persistent nausea, stomach pain, or vomiting; vomit that looks like blood or coffee grounds.

Mild upset stomach or flushing may occur. These effects are usually temporary and may disappear as your body adjusts to this product. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.

If your doctor has directed you to take this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

See also:
What are the possible side effects of Zinc (Feroglobin Capsules)?

Applies to Zinc (Feroglobin Capsules) sulfate: capsules, tablets

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur while taking Zinc (Feroglobin Capsules) sulfate (the active ingredient contained in Zinc (Feroglobin Capsules))

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe vomiting; unusual restlessness; very dry mouth, eyes, or skin.

Copper (Feroglobin Capsules) has been designed for the demands of modern life. With a wide range of nutrients and trace minerals, Copper (Feroglobin Capsules) gives nutritional support to the area of health which are most relevance to women.

Each cap contains starflower oil 100 mg, evening primrose oil 100 mg, citrus bioflavonoids 10 mg, natural mixed carotenoids 2 mg, vitamin D (as D3 200 IU) 5 mcg, vitamin E 30 mg, vitamin C 60 mg, vitamin K 90 mcg, thiamin (vitamin B1) 10 mg, riboflavin (vitamin B2) 5 mg, niacin (vitamin B3) 36 mg, vitamin B6 10 mg, folic acid 400 mcg, vitamin B12 20 mcg, biotin 50 mcg, pantothenic acid 6 mg, magnesium 100 mg, iron 12 mg, zinc 12 mg, Copper (Feroglobin Capsules) 1500 mcg, manganese 2.5 mg, selenium 100 mcg, chromium 50 mcg, para-aminobenzoic acid (PABA) 30 mg.

No artificial colours, gluten, presevatives, starch or sugar, salt or yeast.

Copper (Feroglobin Capsules) has not been tested on animals.

A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (poaceae). Folic Acid (Feroglobin Capsules) is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. [PubChem]

Each 5 mL syrup contains: Diastase (1:50) 135 mg, pepsin 50 mg, papain BPC 50 mg, vitamin B₁ 5 mg, vitamin B₂ 2 mg, vitamin B₆ 2 mg, vitamin B₁₂ 5 mcg, calcium pantothenate 1 mg and nicotinamide 20 mg.

Iron (Feroglobin Capsules) is a pleasantly flavoured syrup, containing digestive enzymes and vitamins of the B-complex group. Abdominal cramps, flatulence, heartburn and nausea can occur as a result of indigestion. Iron (Feroglobin Capsules) is the ideal cure to facilitate digestion and to strengthen the GIT.

Iron (Feroglobin Capsules)'s balanced formulation provides an ideal supplementation that meets the demands and replenishes vitamins stores in the body.

A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)

Zinc (Feroglobin Capsules) Capsule: Each capsule contains Zinc (Feroglobin Capsules) sulphate monohydrate 54.93 mg, thiamine nitrate 10 mg, riboflavin 10 mg, pyridoxine hydrochloride 3 mg, vitamin B12 (coated) equivalent to cyanocobalamin 15 mcg, ascorbic acid 150 mg, Zinc (Feroglobin Capsules) 1 mg, nicotinamide 50 mg and calcium pantothenate 12.5 mg.

Zinc (Feroglobin Capsules) Syrup: Each 5 mL contains Zinc (Feroglobin Capsules) gluconate 34.9 mg, thiamine mononitrate 2.5 mg, riboflavin 2.5 mg, pyridoxine hydrochloride 1 mg, cyanocobalamin 3 mcg, ascorbic acid 50 mg, d-panthenol 12.5 mg and niacinamide 25 mg in a flavoured liquid glucose sorbitol syrup base.