Enfalyte

A white crystal or crystalline powder used as an Enfalyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.

Fluid and Enfalyte depletion

Decreasing fatigue, muscle cramps, or heat exhaustion due to excessive sweating. The use of Enfalyte for these conditions has not been evaluated or approved by the Food and Drug Administration. It may also be used for other conditions as determined by your doctor.

Enfalyte is an Enfalyte combination. It works by replacing electrolytes in the body.

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What is the most important information I should know about Enfalyte?

Potassium supplements are contraindicated in patients with hyperkalemia since a further increase in serum potassium concentration in such patients can produce cardiac arrest. Hyperkalemia may complicate any of the following conditions: chronic renal failure, systemic acidosis such as diabetic acidosis, acute dehydration, extensive tissue breakdown as in severe burns, adrenal insufficiency, or the administration of a potassium-sparing diuretic (e.g., spironolactone, triamterene, amiloride).

Controlled-release formulations of potassium chloride have produced esophageal ulceration in certain cardiac patients with esophageal compression due to an enlarged left atrium. Potassium supplementation, when indicated in such patients, should be given as an immediate-release liquid preparation.

All solid oral dosage forms of potassium chloride are contraindicated in any patient in whom there is structural, pathological (e.g., diabetic gastroparesis) or pharmacologic (use of anticholinergic agents or other agents with anticholinergic properties at sufficient doses to exert anticholinergic effects) cause for arrest or delay in tablet or capsule passage through the gastrointestinal tract.

Use Enfalyte as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Enfalyte with a full glass of water (8 oz/240 mL).
• If you miss a dose of Enfalyte, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Enfalyte.

INTERACTIONS RELATED TO CALCIUM:

Contra-indication:

Digitalis: serious cardiac arrhythmias or death.

ASSOCIATION TO TAKE INTO ACCOUNT:

Thiazide Diuretics: risk of hypercalcemia by decreasing the urinary excretion of calcium.

INTERACTIONS RELATED TO POTASSIUM:

Contra-indication:

Diuretics (amiloride, potassium canrenoate, spironolactone, triamterene) alone or in combination: hyperkalemia is potentially lethal, especially in renal impairment (additive effects hyperkaliémiants).

Combination not recommended:

- Angiotensin-converting enzyme (ACE): hyperkalemia is potentially lethal, especially in renal impairment (additive effects hyperkaliémiants).

- Tacrolimus: hyperkalemia is potentially lethal, especially in renal impairment (additive effects hyperkaliémiants).

INTERACTIONS RELATED TO MAGNESIUM:

Combination not recommended:

Quinidine: Increased plasma levels of quinidine and risk of overdose (decreased renal excretion of quinidine by alkalinization of urine).

INCOMPATIBILITY WITH CERTAIN ANTIBIOTICS Physical chemistry:

Amphotericin B (IV).

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What are the possible side effects of Enfalyte?

Potential side effects (chills, nausea, vomiting...) may appear in severe renal impairment, overdose or too rapid rate of administration.