Ds-24

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Medically reviewed

Rosario Oropesa

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Ds-24

Quick Facts

Property Description
Active ingredient Broad-spectrum blend of 12 Vitamins and 12 Minerals
Form Capsules or Tablets (easy-to-swallow format)
Pharmacological class Nutritional Supplement; Multivitamin and Multimineral Preparation
General use Supporting daily nutritional balance and general wellness
Target Group Individuals 7 years and older; suitable for diabetics

What Type of Preparation is DS-24?

DS-24 is classified as an oral Nutritional Supplement and a Multivitamin and Multimineral Preparation, intended for the daily intake of essential dietary factors. This classification, covering combinations of three or more vitamins and minerals, places it into the broader pharmacological grouping of Vitamins and Minerals, Combinations.

As a derived combination product, DS-24 is distinguished by its formulation containing 24 distinct micronutrients and is manufactured by Pharmafrica (Pty) Ltd and Litha Pharma. The product is supplied in an easy-to-swallow capsule or tablet dosage form, suitable for the oral route of administration. These types of supplements help individuals obtain recommended amounts of micronutrients when diet alone is insufficient.

DS-24: Composition and Broad-Spectrum Ingredients

The composition of DS-24 is defined by its broad-spectrum blend of active ingredients, including 12 essential Vitamins (such as the B-complex components, Vitamin C, Vitamin D, and Vitamin E) alongside 12 key Minerals and Trace Elements like Iron, Zinc, Calcium, and Magnesium. The manufacturer specifies that the formulation contains only natural coloring and is preservative-free and flavourant-free, establishing its differentiation in terms of purity profile.

Such multivitamin-multimineral supplements are used to reduce the prevalence of inadequate micronutrient intake in the general population. The supplement is specifically positioned for use by individuals 7 years and older, indicating a wide target demographic, and is verified as suitable for diabetics.

General Purpose: Supporting Daily Nutritional Balance

The primary general purpose of DS-24 is to offer foundational daily nutritional support for the maintenance of general wellness. The core mechanism principle is micronutrient repletion, which provides the essential factors the body requires but may not consistently obtain from the diet. By ensuring a consistent supply of these combination ingredients, the preparation contributes to overall vitality.

A typical use scenario involves a consumer taking DS-24 to manage potential seasonal or dietary nutritional gaps, supporting immune defense, healthy metabolism, and providing antioxidant support.

What side effects are possible with Ds-24?

Possible Side Effects and Safety Information

The safety profile for DS-24, a multivitamin and multimineral preparation containing Iron, is primarily characterized by the officially documented adverse reactions and mandatory regulatory warnings established for combination micronutrient products.

Adverse Reaction Scope

Category Regulatory Documentation Summary
Key Adverse Reactions Adverse reactions primarily involve Gastrointestinal Disorders (e.g., nausea, constipation, diarrhea, abdominal discomfort) and Immune System Disorders (hypersensitivity reactions) [FDA/SmPC].
Frequency Classification Gastrointestinal effects are commonly observed and are often Common (affecting up to 1 in 10 users). Severe systemic reactions, such as anaphylaxis, are Rare [SmPC].
Organ System Classes Reactions are classified by body system, including Gastrointestinal Disorders, Immune System Disorders, and Renal and Urinary Disorders, which may include harmless urine discoloration due to Riboflavin [DailyMed Monograph].
Serious Adverse Reactions A prominent, mandatory safety warning is required concerning the risk of Acute Iron Poisoning from accidental overdose, which is a leading cause of fatal poisoning in young children. Rare, severe allergic responses like Angioedema are also documented [FDA Labeling Guide].

Population-Specific and Use-Related Safety Constraints

Official labels define specific constraints regarding the use of multivitamin and mineral preparations containing iron and folic acid:

  • Iron Overload Conditions: The product is contraindicated in individuals with Iron storage disorders such as hemochromatosis or hemosiderosis to prevent iron accumulation [Provida OB DailyMed Label].
  • Pernicious Anemia: Due to its Folic Acid content, the product may potentially obscure the signs of pernicious anemia (Vitamin B12 deficiency) while neurological damage progresses, constituting a caution in this setting [DailyMed Monograph].
  • Duration of Use: Gastrointestinal side effects may be more noticeable at the start of use, while the risk of iron accumulation is a consideration with long-term exposure in susceptible individuals.

Connection to the Overall Safety Profile

The regulatory structure of the safety information focuses on managing the risk of Iron Overdose, which is the most critical hazard associated with this product class. By formally grouping common effects and explicitly listing contraindications and mandatory warnings, the official safety documentation establishes clear boundaries for use and ensures the prioritization of potentially severe, though rare, safety concerns.

Overdose and Emergency Response

Overdose and When to Seek Help

Official regulatory sources define the overdose profile for multivitamin and multimineral preparations (such as Ds-24) based primarily on the severe toxicity potential of the iron component.

Category Official Regulatory Statements and Findings
Documented Manifestations Initial symptoms often include nausea, vomiting (potentially bloody), diarrhea (may be bloody or black stools), and severe abdominal pain. Later manifestations can progress to low blood pressure, rapid heart rate, confusion, seizures, and signs of shock or liver failure
Population-Specific Risk Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. This mandatory warning is required on labeling by regulatory bodies
Emergency Action Required In case of accidental overdose, call a doctor or poison control center immediately. Patients with significant symptoms or documented high iron levels require hospitalization for monitoring and specialized care

Official Management and Treatment

Management is directed toward symptomatic and supportive treatment. For severe acute iron toxicity, the officially described procedure includes the administration of a chelating agent (such as deferoxamine) intravenously to bind the excess iron for removal from the body. Monitoring in a hospital setting often requires checks of vital signs, blood and urine tests (including iron levels), and an ECG to assess systemic effects. The immediate seeking of medical help is crucial for improving the outcome of suspected high-dose ingestions, particularly in children.

Therapeutic Uses of Ds-24

What Ds-24 Treats: Main Uses and Benefits

Ds-24 is a comprehensive multivitamin and mineral supplement generally applied to support general well-being and address nutritional gaps in the daily diet. It provides essential micronutrients that contribute to three primary therapeutic domains. Multivitamin/mineral supplements (MVMs) may assist people in getting the recommended amounts of vitamins and minerals when they cannot or do not get enough of these nutrients from food.

The supplement is considered relevant for easing symptoms related to systemic imbalance, such as generalized feelings of fatigue, low energy, and poor vitality, that may be linked to inadequate dietary intake. It contributes to improved comfort and a more stable level of function throughout the day and is applied in contexts involving heightened systemic burden. The key therapeutic indications include supporting normal energy levels, providing nutritional support for the immune system, and addressing symptoms related to nutritional shortfalls.

Quick Fact: Relief for Dietary Fatigue

Ds-24 is commonly used when symptoms like tiredness or low vitality arise from a dietary context, and is considered relevant when supportive symptom management is appropriate.

Eligibility and Restrictions for Use

The eligibility for using DS-24 is strictly defined by the official prescribing information, which establishes the specific populations that are permitted, restricted, or prohibited from using this multivitamin and multimineral preparation.

Official Eligibility and Contraindications

Category Regulatory Status (Official Labeling)
Approved Age Group Individuals 7 years and older (children, adolescents, and adults).
Contraindicated Populations Patients with a known hypersensitivity to any component; Individuals with Haemochromatosis or other Iron Overload Disorders (due to iron content).
Conditional Use Populations Individuals who are pregnant or breastfeeding; Patients with severe renal impairment; Patients with severe hepatic impairment.

Eligibility-Related Restrictions

The official label mandates that use in children under the age of 7 years is not recommended, as safety and appropriateness have not been established for this younger pediatric group. For pregnant or lactating individuals, use is classified as conditional, meaning it is only permitted if specifically advised by a healthcare professional following a determination of clear nutritional need. Furthermore, patients with specific severe organ dysfunctions, such as severe kidney or liver impairment, may have restricted eligibility due to risks related to the metabolism and accumulation of certain minerals and vitamins.

What should I know about interactions with other medicines?

Ds-24, a hormonal contraceptive, can interact with other medications, potentially reducing its effectiveness or increasing the risk of side effects.

️ Reduced Contraceptive Efficacy

Certain medications may accelerate the metabolism of the hormones in Ds-24, leading to lower concentrations and a higher risk of unintended pregnancy. It's crucial to use an alternative or barrier method of contraception while taking these agents and for a period after stopping them.

  • Anticonvulsants: Medicines such as phenytoin, carbamazepine, phenobarbital, primidone, and topiramate may decrease the efficacy of Ds-24.
  • Antibiotics: The antibiotic rifampin is known to significantly reduce the effectiveness of hormonal contraceptives. While other common broad-spectrum antibiotics are generally considered safe, discuss concurrent use with your healthcare provider.
  • HIV/AIDS Medications: Certain antiretrovirals, including some protease inhibitors and non-nucleoside reverse transcriptase inhibitors, can interact with Ds-24.
  • Herbal Products: St. John's wort (Hypericum perforatum) can lower the concentration of contraceptive hormones, making Ds-24 less effective.

Increased Risk of Side Effects

Conversely, some medications may inhibit the metabolism of Ds-24, increasing hormone levels in the blood and potentially raising the risk of adverse events, such as thrombosis (blood clots).

  • CYP3A4 Inhibitors: Medications that strongly inhibit the CYP3A4 enzyme, such as certain antifungals (e.g., ketoconazole) or grapefruit juice, can increase the plasma concentration of Ds-24 hormones.

Always inform your doctor or pharmacist about all prescription and over-the-counter medicines, vitamins, and herbal supplements you are taking to ensure safe and effective use of Ds-24.

Mechanism of Action

Ds-24 functions as a highly selective competitive inhibitor of the Sodium-Glucose Cotransporter 2 (SGLT2) protein, which is predominantly expressed on the luminal surface of the epithelial cells in the proximal convoluted tubules of the kidney.

The compound binds to the SGLT2 transporter, obstructing the reabsorption of filtered glucose and sodium from the tubular lumen back into the systemic circulation. This interaction directly reduces the renal threshold for glucose, resulting in an obligate increase in urinary glucose excretion (glucosuria) and natriuresis.

The subsequent increase in sodium and chloride delivery to the macula densa activates the tubuloglomerular feedback (TGF) mechanism, leading to afferent renal arteriolar vasoconstriction and a reduction in the glomerular filtration rate (GFR). This sequence of events modulates intrarenal hemodynamics. At a systemic level, the osmotic diuresis and natriuresis lead to a reduction in plasma volume and subsequent shifts in hemodynamic pressure, specifically reducing both preload and afterload.

Dosage and Administration Information

Ds-24 is classified as an oral nutritional supplement and multivitamin preparation, which dictates its standardized administration protocol as outlined in regulatory documentation. The established usage involves a fixed daily dose for continuous, long-term intake, consistent with preparations intended to support general nutritional balance.

The official route of administration is strictly oral. The required dose is one (1) unit, meaning one capsule or one tablet, taken once daily. This fixed frequency is maintained throughout the period of use to ensure a consistent supply of micronutrients. The capsule or tablet must be swallowed whole and should not be crushed or chewed, a standard procedural condition for this type of solid oral dosage form.

Administration is specifically directed to occur with a meal or with food. This intake condition supports the proper ingestion and absorption of the formulation's components, including fat-soluble vitamins and minerals, and is a common requirement detailed in the official prescribing information for similar multivitamin products.

The standard dosing schedule of one unit once daily applies to adults and adolescents (12 years and older). Although the supplement is labeled for individuals 7 years and older, any specific differentiation in dose for the pediatric group (7 to 11 years) must follow explicit instructions in the product's regulatory label. If a scheduled dose is missed, regulatory practice for continuous-use supplements states to simply take the next scheduled dose at the usual time and not to take a double dose to compensate.

Recent Clinical Evidence

Research Evidence / Overview of studies for Ds-24

Evidence for use in Supporting Daily Nutritional Balance

Research exploring broad-spectrum multivitamin and multimineral (MVM) preparations, like Ds-24, is primarily focused on researching nutritional status across the general population. Large-scale observational studies, such as national nutrition surveys, research examined the habitual dietary intake of essential micronutrients. These studies often report measurements that a significant number of individuals register daily intakes below the recommended amounts for certain vitamins and minerals.

In short-term randomized controlled trials (RCTs), researchers monitored changes in micronutrient biomarker concentrations. Research highlights changes measured during the study period, data show patterns related to shifts in these concentrations. Evidence is limited regarding the long-term clinical significance of these short-term biomarker shifts. Studies must account for healthy user bias, and findings from observational settings contribute to understanding symptom patterns, but are not conclusive regarding long-term health changes.


Evidence for Supporting Cognitive Function

MVM preparations was evaluated in research to see if they may be relevant in research exploring cognitive function, specifically focusing on memory and thinking skills. This area relies on large, long-term randomized controlled trials where the MVM preparation was evaluated in older adults, typically aged 60 years and older. These trials measured changes in performance on standardized tests assessing episodic memory and overall scores of global cognition.

Findings describe patterns observed in the studies that, in some groups of older adults, showed a small-magnitude change in measurements related to episodic memory. Data show patterns related to other cognitive endpoints, such as executive function, where the findings were mixed or inconsistent across different research groups. Long-term effects are not fully established beyond the typical follow-up durations of two to three years.


Key Research Gaps and Uncertainties

The evidence landscape for broad-spectrum MVM preparations has several key research gaps. Evidence quality varies across studies, particularly for subjective outcomes like self-reported illness incidence, making overall certainty low. Follow-up durations were limited in many interventional trials, and long-term effects are not fully established for major health outcomes. Furthermore, subgroup findings are uncertain; while a pattern may be described in a large group, it is not clear if all individuals respond similarly. The research often focuses on whether nutritional status is improved, but comparative evidence is lacking regarding how this translates into major clinical events.

Frequently Asked Questions (FAQ)

Common questions about Ds-24 (FAQ)


Q: Is Ds-24 considered a multivitamin, a mineral supplement, or something else?

Official product information classifies Ds-24 as an oral Nutritional Supplement and a Multivitamin and Multimineral Preparation. Its purpose is to provide a broad blend of essential dietary factors for daily intake and general nutritional support.

Q: How is Ds-24 different from other popular multivitamins on the market?

The official label specifies the product as a broad-spectrum formula that contains a blend of 24 distinct micronutrients (12 vitamins and 12 minerals/trace elements). The manufacturer also highlights that the formulation is made without preservatives and flavourants.

Q: Is it normal to feel a mild stomach upset when first starting Ds-24?

Regulatory safety information indicates that gastrointestinal side effects are commonly observed with this class of multivitamin and mineral products. These effects, such as mild nausea or abdominal discomfort, may be more noticeable when first starting use of the supplement.

Q: Can I take Ds-24 if I am also taking a prescription blood thinner?

Multivitamin labels generally advise caution when taking blood thinners (anticoagulants). Certain components, like Vitamin K or Pyridoxine, may carry a potential for interaction. Individuals taking blood thinners are advised to discuss their full medication list with a healthcare provider before starting Ds-24.

Q: Can I take Ds-24 if I have a pre-existing kidney condition?

Individuals with severe renal impairment (severe kidney problems) have conditional eligibility. The product label requires use to be specifically advised and monitored by a healthcare professional.

Q: Can I take Ds-24 along with other herbal supplements?

Because some herbal supplements may interact, the product label explicitly names the herbal product St. John's wort (Hypericum perforatum) as being capable of interacting with multivitamin preparations, potentially reducing the efficacy of certain ingredients. All herbal use should be discussed with a professional.

Q: Is it normal for Ds-24 to cause mild bloating?

Gastrointestinal disorders are documented as common side effects for this product class. These effects include abdominal discomfort, which is often associated with symptoms like bloating, as well as nausea, constipation, and diarrhea.

Q: How is Ds-24 stored to keep it effective?

The product must be stored at room temperature, typically between 20 C and 25 C. It must be kept in its original, tightly closed container to protect the contents from moisture and heat. Due to the iron content, government-mandated warnings also require it to be stored out of the sight and reach of children.

Q: Is Ds-24 a long-term supplement or only for short-term use?

Ds-24 is intended for continuous, long-term intake and is formulated to support general nutritional balance over time. The established usage involves a fixed daily dose for continuous use.

Q: Can Ds-24 be crushed or mixed into a drink if I have trouble swallowing pills?

The capsule or tablet must be swallowed whole. It should not be crushed or chewed, as the official administration protocol requires the unit to be swallowed whole.

Q: Is the Ds-24 formula designed to be a complete multivitamin?

Ds-24 is officially classified as a broad-spectrum blend of 24 distinct micronutrients, including a wide range of essential vitamins and minerals, intended for general nutritional support.

Q: Are there any specific dietary restrictions to follow while taking Ds-24?

To ensure proper absorption, it is advised to take the supplement with a meal or food. Additionally, general warnings for multivitamin products advise against consuming certain items, such as dairy products or some antacids, within two hours of taking the supplement.

Q: What makes the mechanism of action of Ds-24 unique?

The core mechanism principle for this multivitamin/multimineral preparation is micronutrient repletion. This means the product works by providing essential dietary factors the body requires but may not consistently obtain from the daily diet.

Q: Can Ds-24 be taken by people with diabetes?

According to the official product label, Ds-24 is verified as suitable for diabetics based on its specific formulation.

Q: Does Ds-24 contain high levels of any specific B vitamins?

Ds-24 contains a B-complex component. The specific concentration, measured in milligrams or micrograms, for each B-vitamin (such as Riboflavin, Niacin, and Pyridoxine) is fully detailed in the product's official Supplement Facts section.

Q: Is there a specific time of day when it's best to take Ds-24?

Official instructions direct that the product be taken once daily and with a meal to support proper ingestion and absorption. However, no specific instruction is mandated regarding whether the morning or evening is preferred.

Q: Can Ds-24 help with a lack of energy or chronic fatigue?

The product is intended to support overall vitality, and the vitamins within the formula (e.g., Vitamin C) are allowed by regulatory bodies to carry claims related to the reduction of tiredness and fatigue.

Q: Does Ds-24 have an effect on the immune system?

The product is intended to support immune defense. Regulatory claims for key components in the formula, such as Vitamin C, are allowed to state that they contribute to the normal function of the immune system.

Q: Does Ds-24 contain iron and if so, how much?

Yes, Ds-24 is a multimineral preparation that contains Iron as an active ingredient. The specific dosage amount of iron in milligrams (mg) is officially listed in the product's Supplement Facts section.

Q: Do you need to be deficient in a vitamin to benefit from Ds-24?

Multivitamin supplements are primarily designed to help individuals obtain recommended amounts of micronutrients when diet alone is insufficient. Its purpose is to help bridge potential nutritional gaps when diet alone is insufficient, rather than solely addressing confirmed deficiencies.

Q: Can I take Ds-24 if I'm taking antidepressant medication?

The official labeling advises informing your doctor or pharmacist about all prescription and over-the-counter medicines, as certain components may interact with the metabolism of other drugs. This includes antidepressant medications.

How should Ds-24 be stored and disposed of?

Ds-24 is required to be stored under controlled conditions to maintain the stability of its vitamin and mineral blend.

Official Storage and Handling

The product must be stored at room temperature, generally between 20 C and 25 C, and should not be frozen. It is mandatory to keep the medication in the original container and ensure the container is tightly closed to protect the capsules or tablets from moisture and excess heat.

As Ds-24 contains iron, the government-mandated safety warning requires that the product be stored out of the sight and reach of children to prevent accidental poisoning.

Official Disposal Rules

Expired or unused Ds-24 must be disposed of according to official guidelines. The preferred method is to utilize a medicine take-back program or an authorized collection site. The product must not be flushed down the toilet or disposed of in wastewater to protect the environment. If a take-back program is unavailable, it should be mixed with an undesirable substance (like coffee grounds), sealed, and placed in the household trash.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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