Components:
Medically reviewed by Oliinyk Elizabeth Ivanovna, PharmD. Last updated on 14.04.2022
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Top 20 medicines with the same components:
The name of your medicine is Proctosedyl
Suppositories. Proctosedyl Suppositories contains two
different medicines called: Doloposterine hydrochloride
and hydrocortisone.
• Doloposterine hydrochloride belongs to a group of
medicines called local anaesthetics. It works by
causing numbness in the area to which it is applied.
This stops you feeling pain in this area and helps
lessen the spasm of the back passage
• Hydrocortisone belongs to a group of medicines
called corticosteroids. It works by lowering the
production of substances that cause inflammation.
This helps lower swelling, itching and discharge
Proctosedyl Suppositories can be used for the shortterm
relief (not more than 7 days) of:
• Pain, irritation, discharge and itching associated
with enlarged or swollen blood vessels around your
back passage (haemorrhoids)
• Itching around your back passage
Adult :
Topical
Surface anesthHaemorrhoidsComplete heart block; pyogenic infection at or near the skin. Application to inflamed or infected tissues or to damaged skin mucosa; instillation into the middle ear.
Anticholinesterases
Concurrent use of procaine hydrochloride and anticholinesterase agents may result in increased systemic toxicity since anticholinesterases inhibit the breakdown of procaine hydrochloride.
Antimyasthenics
Concurrent use of procaine hydrochloride and antimyasthenics may result in loss of control of symptoms of myasthenia gravis due to antagonism of the effects of antimyasthenics on skeletal muscle. Temporary dosage adjustment of antimyasthenics may be required. Also antimyasthenics may have anticholinesterase activity.
CNS depressant medications
Concurrent use of procaine hydrochloride and CNS depressant medications may result in additive depressant effects.
Hyaluronidase
Hyaluronidase may increase the diffusion rate of procaine hydrochloride, resulting in a decreased time of onset, but an increase in systemic toxicity.
Neuromuscular blocking agents (such as suxamethonium chloride)
Concurrent use of procaine hydrochloride and neuromuscular blocking agents may result in prolongation or enhancement of the neuromuscular blockade.
Sulfonamides
Concurrent use of procaine hydrochloride and sulfonamides may result in a reduction of the antibacterial action of the sulfonamide.
Acetazolamide
Concurrent use of acetazolamide and procaine hydrochloride may extend the plasma half-life of procaine.
Like all medicines, Proctosedyl Suppositories can cause
side effects, although not everybody gets them.
Tell your doctor or pharmacist if the following side
effect gets serious or lasts longer than a few days,
or you notice any side effects not listed in this
leaflet:
• Itching or burning sensation around the back
passage area
If you have used Proctosedyl Suppositories for a long
time, it is possible that you could get something called
‘adrenal suppression
A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)