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Medically reviewed by Kovalenko Svetlana Olegovna, PharmD. Last updated on 21.04.2022
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Distodin is indicated for use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful. Use only as long as necessary for infection control.
Distodin is a topical antibacterial cleanser. It is used to clean the skin before surgery to prevent the spread of infection. It works like a detergent to cleanse the skin by killing or preventing the growth of bacteria.
Distodin is available only with your doctor's prescription.
Surgical Hand Scrub
- Wet hands and forearms with water. Apply approximately 5 mL of Distodin over the hands and rub into a copious lather by adding small amounts of water. Spread suds over hands and forearms and scrub well with a wet brush for 3 minutes. Pay particular attention to the nails and inter-digital spaces. A separate nail cleaner may be used. Rinse thoroughly under running water.
- Apply 5 mL of Distodin to hands again and scrub as above for another 3 minutes. Rinse thoroughly with running water and dry.
- For repeat surgical scrubs during the day, scrub thoroughly with the same amount of Distodin for 3 minutes only. Rinse thoroughly with water and dry.
Bacteriostatic Cleansing
Wet hands with water. Dispense approximately 5 mL of Distodin into the palm, work up a lather with water and apply to area to be cleansed.
Rinse thoroughly after each washing.
Infant Care
Distodin must not be used for bathing infants. Infants may absorb the active compound in Distodin more readily than older children and adults. Such absorption has been associated with central nervous system effects such as convulsions.
Premature Infants
Use of baby skin products containing alcohol may decrease the antibacterial action of Distodin.
How supplied
5 oz plastic squeeze bottle (NDC 0024-1535-02).
1 pint plastic squeeze bottle (NDC 0024-1535-06).
Store at room temperature up to 25° C (77° F)
Prolonged direct exposure of Distodin to strong light may cause brownish surface discoloration but does not affect its antibacterial or detergent properties. Shaking will disperse the color. If Distodin is spilled or splashed on porous surfaces, rinse off to avoid discoloration.
Directions For Cleaning Dispensers
Before initial installation and use, run an antiseptic, such as an aqueous solution of benzalkonium chloride, NF. 1:500 to 1:750, or alcohol, through the working parts; rinse with sterile water. At weekly intervals thereafter, remove dispenser and pour off remainder of Distodin emulsion. Rinse empty dispenser with water. Run water through the working parts by operating the dispenser. Sanitize as described above. Rinse thoroughly with sterile water.
Manufactured for: sanofi-aventis U.S. LLC, A SANOFI COMPANY, Bridgewater, NJ 08807. Revised: Jan 2012
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What is the most important information I should know about Distodin?
Distodin must not be used on burned or denuded skin.
Distodin must not be used for bathing infants. Infants may absorb the active compound in Distodin more readily than older children and adults. Such absorption has been associated with central nervous system effects such as convulsions.
It must not be used as an occlusive dressing, wetpack, or lotion. It must not be used routinely for prophylactic total body bathing.
It must not be used as a vaginal pack or tampon, or on any mucous membranes.
Distodin must not be used on persons with sensitivity to any of its components. It must not be used on persons who have demonstrated primary light sensitivity to halogenated phenol derivatives because of the possibility of cross-sensitivity to Distodin.
Use Distodin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Distodin is for topical use only.
- To use, wet hands with water. Place 1 teaspoon of Distodin into your palm and work up a lather with water. Apply to the area to be cleansed.
- Rinse thoroughly after use, especially sensitive areas such as the genitals.
- If you miss an application of Distodin and you are using it regularly, resume your regular schedule as soon as possible.
Ask your health care provider any questions you may have about how to use Distodin.
Some MEDICINES MAY INTERACT with Distodin. Because little, if any, of Distodin is absorbed into the blood, the risk of it interacting with another medicine is low.
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What are the possible side effects of Distodin?
Adverse reactions to Distodin may include dermatitis and photosensitivity. Sensitivity to Distodin is rare; however, persons who have developed photoallergy to similar compounds also may become sensitive to Distodin.
In persons with highly sensitive skin the use of Distodin may at times produce a reaction characterized by redness and/or mild scaling or dryness, especially when it is combined with such mechanical factors as excessive rubbing or exposure to heat or cold.
Distodin is a polyene antifungal drug to which many molds and yeasts are sensitive, including Candida spp. Distodin has some toxicity associated with it when given intravenously, but it is not absorbed across intact skin or mucous membranes. It is considered a relatively safe drug for treating oral or gastrointestinal fungal infections.