Diligan-25

Oral

Motion sickness

Adult: 25-50 mg 1 hr before travelling and repeat 24 hrly if needed.

Child: 2-6 yr 6.25 mg once daily; >6-12 yr 12.5 mg once daily; >12 yr Same as adult dose. Doses are given 1 hr before travelling and repeated 24 hrly if needed.

Oral

Vertigo and vestibular disorders

Adult: 25-100 mg daily in divided doses. Discontinue if there is no response after 1-2 wk of treatment.

Child: ≥12 yr Same as adult dose.

How should I use Diligan-25?

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Use Diligan-25 as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Diligan-25 by mouth with or without food.
• For prevention of motion sickness, take Diligan-25 at least 1 hour before activity or travel.
• Use Diligan-25 exactly as directed on the package, unless instructed differently by your doctor. If you are taking Diligan-25 without a prescription, follow any warnings and precautions on the label.
• If you miss a dose of Diligan-25 and are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Diligan-25.

Diligan-25 description

A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.

Diligan-25 dosage

Vertigo

For the control of vertigo associated with diseases affecting the vestibular system, the recommended dose is 25 to 100 mg daily, in divided dosage, depending upon clinical response.

Motion Sickness

The initial dose of 25 to 50 mg of Diligan-25 should be taken one hour prior to embarkation for protection against motion sickness. Thereafter, the dose may be repeated every 24 hours for the duration of the journey.

How supplied

Diligan-25®: 12.5 mg tablets: Bottles of 100 (NDC 0049-2100-66)

Diligan-25®/25: 25 mg tablets: Bottles of 100 (NDC 0049-2110-66)

Diligan-25®/50: 50 mg tablets: Bottles of 100 (NDC 0049-2140-66)

Distributed by: Roerig Division of Pfizer Inc, NY, NY 10017. October 2012

Diligan-25 interactions

See also:
What other drugs will affect Diligan-25?

The following drug interactions and/or related problems have been selected on the basis of their potential clinical significance (possible mechanism in parentheses where appropriate)—not necessarily inclusive (» = major clinical significance):

Note: Combinations containing any of the following medications, depending on the amount present, may also interact with this medication.

Alcohol or

CNS depression–producing medications, other (concurrent use may potentiate the CNS depressant effects of either these medications or buclizine)

Anticholinergics or other medications with anticholinergic activity (concurrent use with buclizine may potentiate anticholinergic effects)

Apomorphine (prior administration of buclizine may decrease the emetic response to apomorphine)

Diligan-25 side effects

See also:
What are the possible side effects of Diligan-25?

Applies to meclizine: oral capsule, oral tablet, oral tablet chewable

In addition to its needed effects, some unwanted effects may be caused by meclizine (the active ingredient contained in Diligan-25). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking meclizine:

Incidence not known:

• Cough
• difficulty swallowing
• dizziness
• drowsiness
• fast heartbeat
• hives
• itching
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• shortness of breath
• skin rash
• tightness in the chest
• unusual tiredness or weakness

Minor Side Effects

Some of the side effects that can occur with meclizine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Rare

• Blurred vision

• Dry mouth
• headache

Diligan-25 (meclizine) is an antihistamine that reduces the effects of natural chemical histamine in the body.

Diligan-25 is used to treat or prevent nausea, vomiting, and dizziness caused by motion sickness. It is also used to treat symptoms of vertigo (dizziness or spinning sensation) caused by disease that affects your inner ear.

Diligan-25 may also be used for purposes not listed in this medication guide.

See also:
What is the most important information I should know about Diligan-25?

Diligan-25 hydrochloride is contraindicated in individuals who have shown a previous hypersensitivity to it.