Medically reviewed by Kovalenko Svetlana Olegovna, PharmD. Last updated on 2022-03-23
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Top 20 medicines with the same components:
Dexamethasone, Gentamicin Sulfate
infections of the anterior segment of the eye caused by gentamicin-sensitive microflora (conjunctivitis, keratitis, blepharitis, barley),
allergic processes in the anterior segment of the eye, accompanied by bacterial infection,
prevention and treatment of inflammatory phenomena in the postoperative period (cataract removal, anti-glaucomatous operations).
Conjunctivally. A strip of ointment 1 cm long is laid 2-3 times a day.
During the application of the eye ointment Dexa-Gentamicin, avoid contact of the tube with the surface of the skin or conjunctiva.
With the simultaneous use of several eye drugs, it is recommended to lay the eye ointment Dexa-Gentamicin no earlier than 15 minutes after the use of eye drops.
The duration of treatment with Dexa-Gentamicin usually does not exceed 2-3 weeks.
hypersensitivity to any of the components of the drug,
keratitis caused by Herpes zoster (tree keratitis), chickenpox and other viral diseases of the cornea and conjunctiva,
mycobacterial infections of the eye,
fungal diseases of the eye,
acute purulent diseases of eyes with lesions of the corneal epithelium,
trauma and ulcerative lesions of the cornea,
wearing contact lenses,
I trimester of pregnancy,
children under 18 years of age (due to the lack of data on efficacy and safety).
In rare cases, after laying the ointment, an allergic reaction and a burning sensation are possible.
Long-term use of the drug can cause secondary glaucoma and steroid cataracts, so when using the drug for more than 2 weeks, as well as in patients with a history of glaucoma, it is recommended to regularly monitor IOP.
Possible occurrence of contact dermatitis, herpetic keratitis, corneal perforation in the presence of keratitis, fungal infection, increased severity of bacterial infection of the cornea, ptosis, mydriasis. When used after corneal injuries, it can lead to a slowdown in its healing.
In case of side effects, you should stop using the drug and contact an ophthalmologist as soon as possible.
With topical application of the drug Dexa-Gentamicin eye ointment, an overdose is unlikely.
A combined remedy, the effect of which is due to the components included in its composition. It has anti-allergic, anti-inflammatory and antibacterial effects.
Dexamethasone-GCS-has a pronounced anti-inflammatory effect, the index of its relative anti-inflammatory activity is 30.
Gentamicin sulfate-an antibiotic of the aminoglycoside group-is characterized by a wide spectrum of action, active against most gram-negative and gram-positive microorganisms (Pseudomonas aeruginosa, Escherichia coli, Proteus spp., Klebsiella spp., Serratia spp., Salmonella spp.). Moderately active against strains Staphylococcus spp.
When applied topically, dexamethasone penetrates well into the corneal epithelium and conjunctiva, while therapeutic concentrations are achieved in the watery moisture of the eye, with inflammation or damage to the mucous membrane, the rate of penetration increases.
Gentamicin sulfate, when applied topically, is found in therapeutic concentrations in the corneal stroma, in the moisture of the anterior chamber, and in the vitreous body for 6 hours. Gentamicin sulfate does not enter the systemic bloodstream through the intact corneal epithelium.
- Glucocorticosteroid for topical use antibiotic-aminoglycoside [Glucocorticosteroids in combinations]
- Glucocorticosteroid for topical use antibiotic-aminoglycoside [Ophthalmic agents in combinations]
When combined with atropine, other cholinolytic or mydriatic drugs, an increase in the level of IOP is possible.
When applied topically, gentamicin is incompatible with amphotericin B, heparin, sulfadiazine, cephalotin, and cloxacillin. Topical application of these drugs together with gentamicin can lead to the deposition of precipitates in the conjunctival cavity.