Corvita

Corvita Wafers are indicated to help, along with diet, the treatment of calcium deficiency, skeletal weakness and osteoporosis. Corvita Wafers supplementation may be beneficial to individuals who have an insufficient dietary intake of the nutrients in this formulation. Calcium and vitamin D supplementation may be useful in both preventing and treating osteoporosis. Vitamin D supplementation may be beneficial to those who are institutionalized and/or have reduced exposure to sunlight. Folic acid, vitamin B6 and vitamin B12 may help reduce the risk of cardiovascular disease by lowering blood levels of homocysteine. If dietary intake of calcium is inadequate, patients currently taking bisphosphonates for osteoporosis treatment should be instructed to take calcium and vitamin D daily.

Treating or preventing low levels of vitamin B, C, and zinc. It may also be used for other conditions as determined by your doctor.

Corvita is a vitamin and mineral combination. It works by providing vitamins and minerals to the body to help meet nutritional needs.

The FDA has not approved Corvita to treat these conditions.

Usual Adult Dose for Vitamin/Mineral Supplementation

Antioxidant Multiple Vitamins (A,D,E,K-intensive) and Minerals oral capsule:

2 capsules orally once daily.

Calcium, Magnesium and Phosphorus oral tablet:

2 tablets orally 3 times per day.

Calcium with Vitamin D and K oral tablet:

1 tablet orally twice daily.

Multiple Vitamins with Zinc oral capsule:

2 capsules orally once daily.

Therapeutic Multiple Vitamins with Minerals oral tablet, chewable:

1 tablet chewed daily with food.

Vitamin B Complex with C and Calcium oral tablet:

3 tablets orally daily preferably after a meal.

Vitamin B Complex with C, Folic Acid, Iron and Zinc oral tablet:

1 tablet orally once daily.

Vitamin B Complex with D, Calcium and Folic Acid oral wafer:

1 wafer chewed twice daily.

Vitamin B Complex with Folic Acid and Minerals oral tablet:

1 to 2 tablets orally once or twice daily.

Usual Pediatric Dose for Vitamin/Mineral Supplementation

Antioxidant Multiple Vitamins (A,D,E,K-intensive) and Minerals oral capsule:

4 to 10 years: 1 capsule orally once daily.

11 years or older: 2 capsules orally once daily.

Antioxidant Multiple Vitamins and Minerals oral liquid and

Antioxidant Multiple Vitamins (A,D,E,K-intensive) and Minerals oral liquid:

1 year or less: 1 mL orally once a day.

1 to 3 years: 2 mL orally once a day.

Multiple Vitamins with Zinc oral capsule:

4 to 10 years: 1 capsule orally once daily.

11 years or older: 2 capsules orally once daily.

Vitamin B Complex with Folic Acid and Minerals oral tablet:

6 years or older: 1 to 2 tablets orally once or twice daily.

Renal Dose Adjustments

Patients with impaired kidney function should not take magnesium supplements without physician supervision.

Liver Dose Adjustments

Data not available

Dialysis

Date not available

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What is the most important information I should know about Corvita?

Corvita Wafers are contraindicated in patients with hypersensitivity to any of its ingredients. Calcium and vitamin D supplementation is contraindicated in those with hypercalcemia or conditions that may lead to hypercalcemia and those who form calcium containing stones are generally advised not to take supplemental calcium. Used together, iron and calcium may inhibit the absorption of iron. Concurrent use of quinolones or tetracyclines with calcium may decrease the absorption of these medications. Folic acid is contraindicated in patients with untreated and uncomplicated pernicious anemia, and in those with anaphylactic sensitivity to folic acid. The use of folic acid doses above one milligram per day may precipitate or exacerbate the neurological damage of vitamin B12 deficiency. High doses of folic acid may result in decreased serum levels of the anticonvulsant drugs: carbamazepine, fosphenytoin, phenytoin, phenobarbital, valproic acid.

Use Corvita as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Corvita by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Take Corvita with a full glass of water (8 oz [240 mL]).
• If you are also taking eltrombopag or a tetracycline antibiotic (eg, minocycline), ask your doctor how you should take it with Corvita.
• Many medicines (eg, used for cancer, infection, high potassium levels, immune system suppression, iron supplements, low blood platelets, osteoporosis, thyroid problems) should not be taken at the same time as Corvita; their effectiveness may be decreased. Ask your doctor or pharmacist if your dose of Corvita should be separated from your dose of any of your other medicines.
• If you miss a dose of Corvita, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Corvita.

This product is a combination of B vitamins used to treat or prevent vitamin deficiency due to poor diet, certain illnesses, alcoholism, or during pregnancy. Vitamins are important building blocks of the body and help keep you in good health. B vitamins include thiamine, riboflavin, niacin/niacinamide, vitamin B6, vitamin B12, folic acid, and pantothenic acid.

Some brands of B vitamins also contain ingredients such as vitamin C, vitamin E, biotin, or zinc. Consult your doctor or pharmacist if you have questions about the ingredients in your brand.

How to use Corvita

Take this medication by mouth, usually once daily or as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

If you are taking a brand that contains vitamin C, take this medication by mouth with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise.

If you are taking chewable tablets, chew the tablet thoroughly before swallowing.

If you are taking extended-release capsules, swallow them whole. Do not crush or chew extended-release capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

If you are taking a liquid product, use a medication-measuring device to carefully measure the dose. Do not use a household spoon. Some liquid products need to be shaken before each dose. Some products that contain vitamin B12 need to be placed under the tongue and held there before swallowing. Follow label directions carefully to get the most benefit.

Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day.

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially: certain anti-seizure drugs (e.g., phenytoin), methyldopa.

This product can decrease the absorption of other drugs such as bisphosphonates (for example, alendronate), levodopa, penicillamine, quinolone antibiotics (for example, ciprofloxacin, levofloxacin), thyroid medications (for example, levothyroxine), and tetracycline antibiotics (for example, doxycycline, minocycline). Therefore, separate your doses of these medications as far as possible from your doses of this product. Ask your doctor or pharmacist about how long you should wait between doses and for help finding a dosing schedule that will work with all your medications.

This medication may interfere with certain laboratory tests (e.g., fecal occult blood test), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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What are the possible side effects of Corvita?

Adverse reactions have been reported with specific vitamins and minerals, but generally at levels substantially higher than those in Corvita Wafers. However, allergic and/or idiosyncratic reactions to vitamins even at lower potencies or any ingredient are possible.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-deficiency anemia. Corvita is used to build up the blood in anemia.