Coq LC

Astaxanthin (Coq LC), an anti-oxidant, is used as a supplemental therapy for cancer, ocular diseases, sunburns, male infertility, cardiovascular diseases including stroke and hyperlipidemia.

Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.

Lycopene (Coq LC), an antioxidant, is indicated for the treatment and prevention of cancer, cataract, asthma, HPV infection, atherosclerosis, CVD and prostate cancer. Lycopene (Coq LC) is a good anti-inflammatory agent and anti-oxidant.

Zinc (Coq LC) Capsule: Each capsule contains Zinc (Coq LC) sulphate monohydrate 54.93 mg, thiamine nitrate 10 mg, riboflavin 10 mg, pyridoxine hydrochloride 3 mg, vitamin B12 (coated) equivalent to cyanocobalamin 15 mcg, ascorbic acid 150 mg, folic acid 1 mg, nicotinamide 50 mg and calcium pantothenate 12.5 mg.

Zinc (Coq LC) Syrup: Each 5 mL contains Zinc (Coq LC) gluconate 34.9 mg, thiamine mononitrate 2.5 mg, riboflavin 2.5 mg, pyridoxine hydrochloride 1 mg, cyanocobalamin 3 mcg, ascorbic acid 50 mg, d-panthenol 12.5 mg and niacinamide 25 mg in a flavoured liquid glucose sorbitol syrup base.

Supplement for maintenance of health.

Supplementing the amount of coenzyme Q-10 in the diet.

Coenzyme Q-10 is a dietary supplement.

Levocarnitine (Coq LC)® (Levocarnitine (Coq LC)) is indicated in the treatment of primary systemic carnitine deficiency. In the reported cases, the clinical presentation consisted of recurrent episodes of Reye-like encephalopathy, hypoketotic hypoglycemia, and/or cardiomyopathy. Associated symptoms included hypotonia, muscle weakness and failure to thrive. A diagnosis of primary carnitine deficiency requires that serum, red cell and/or tissue carnitine levels be low and that the patient does not have a primary defect in fatty acid or organic acid oxidation. In some patients, particularly those presenting with cardiomyopathy, carnitine supplementation rapidly alleviated signs and symptoms. Treatment should include, in addition to carnitine, supportive and other therapy as indicated by the condition of the patient.

Levocarnitine (Coq LC)® (Levocarnitine (Coq LC)) is also indicated for acute and chronic treatment of patients with an inborn error of metabolism which results in a secondary carnitine deficiency.

These compounds act mainly as normalizatoare of cellular metabolic process. ale fenomenelor oxidative si de imbatranire. Alterations mentioned processes underlying degenerative processes of cell aging and oxidative phenomena

Patients with deficiency of B-complex vitamins, vitamin C and Zinc (Coq LC) or where supplementation of these vitamins and Zinc (Coq LC) can be beneficial. Such patients and conditions include: Patients who are on prolonged antibiotic therapy; those who are suffering from infection, injuries, burns, fever, illness; patients with diarrhoea and GI disorders; patients who have undergone surgical operations; patients on diet restrictions eg, in diabetes, anorexia and alcoholism and in elderly persons; pregnant and lactating women due to increased nutritional needs.

Coenzyme Q10 (Coq LC) is a vitamin-like substance that is made naturally in the body. This medicine is also known as Coenzima, Ubidcarenone, Ubidécarénone, and Ubiquinol.

Coenzyme Q10 (Coq LC) is likely effective in alternative medicine as an aid in treating coenzyme Q-10 deficiency, or reducing the symptoms of mitochondrial disorders (conditions that affect energy-production in the cells of the body).

Coenzyme Q10 (Coq LC) is also possibly effective in preventing migraine headaches, lowering blood pressure, preventing a second heart attack, or slowing the progression of early Parkinson's disease. This medicine is also possibly effective in improving symptoms in people with congestive heart failure, nerve problems caused by diabetes, Huntington's disease, muscular dystrophy, or macular degeneration (age-related vision loss).

Coenzyme Q10 (Coq LC) has also been used to treat Alzheimer's disease, high cholesterol, or amyotrophic lateral sclerosis (Lou Gehrig's disease). However, research has shown that this medicine may not be effective in treating these conditions.

Research also has shown that Coenzyme Q10 (Coq LC) is not likely to be effective in increasing athletic performance.

Other uses not proven with research have included treating asthma, COPD, cancer, diabetes, certain heart problems, fibromyalgia, hepatitis C, kidney problems, high blood pressure during pregnancy, muscle problems caused by taking "statin" cholesterol medicine, and other conditions.

Coenzyme Q10 (Coq LC) is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

• This product has not been approved by the FDA as safe and effective for any medical condition. The long-term safety of herbal products is not known. Before using any alternative medicine, talk with your doctor or pharmacist.
• If you are using Coenzyme Q10 (Coq LC) chewable tablets for heart failure, do not stop using the product without first consulting your doctor or pharmacist.
• Keep all doctor and lab appointments while you are using this product.
• Diabetes patients - This product may lower blood sugar. Check your blood or urine sugar regularly (daily or as directed). Check with your doctor before changing the dose of your diabetes medicine.
• Use Coenzyme Q10 (Coq LC) chewable tablets with caution in CHILDREN.
• PREGNANCY and BREAST-FEEDING: Coenzyme Q10 (Coq LC) chewable tablets is not recommended for use during pregnancy. If you are or will be breast-feeding while you are using this product, check with your doctor or pharmacist to discuss the risks to your baby.

Levocarnitine (Coq LC) is used to prevent and treat a lack of carnitine. It is used to prevent and treat this condition in patients with kidney disease on dialysis. It is given to people whose body cannot properly use carnitine from their diet. Lack of carnitine can lead to liver, heart, and muscle problems. Your doctor may treat lack of carnitine by prescribing Levocarnitine (Coq LC) for you.

Carnitine comes in two forms. Levocarnitine (Coq LC) (Levocarnitine (Coq LC)) should not be confused with the D,Levocarnitine (Coq LC) form (labeled as “vitamin B T”'). Only the L-form of carnitine is used by the body to treat serious carnitine deficiency. The D,L-form does not help the body use fat and can actually interfere with and cause a lack of Levocarnitine (Coq LC).

Certain Levocarnitine (Coq LC) products have been specifically approved by the U.S. Food and Drug Administration for medical use and are available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, Levocarnitine (Coq LC) is used in certain patients with the following medical condition:

• Carnitine deficiency that results from treatment with valproic acid

Zinc (Coq LC) is a naturally occurring mineral. Zinc (Coq LC) is important for growth and for the development and health of body tissues.

Zinc (Coq LC) sulfate is used to treat and to prevent Zinc (Coq LC) deficiency.

Zinc (Coq LC) sulfate may also be used for purposes not listed in this medication guide.

Adult 1-4 licap once daily.

25 mg: 1-4 softcaps daily. 100 mg: 1 softcap daily.

Levocarnitine (Coq LC)® (Levocarnitine (Coq LC)) Tablets

Adults: The recommended oral dosage for adults is 990 mg two or three times a day using the 330 mg tablets, depending on clinical response.

Infants and children: The recommended oral dosage for infants and children is between 50 and 100 mg/kg/day in divided doses, with a maximum of 3 g/day. Dosage should begin at 50 mg/kg/day. The exact dosage will depend on clinical response.

Monitoring should include periodic blood chemistries, vital signs, plasma carnitine concentrations and overall clinical condition.

Levocarnitine (Coq LC)® (Levocarnitine (Coq LC))

Oral Solution and Levocarnitine (Coq LC)® SF (Levocarnitine (Coq LC)) Sugar-Free

Oral Solution

For oral use only. Not for parenteral use.

Adults: The recommended dosage of Levocarnitine (Coq LC) is 1 to 3 g/day for a 50 kg subject, which is equivalent to 10 to 30 mL/day of Levocarnitine (Coq LC)® (Levocarnitine (Coq LC))

Oral Solution or Levocarnitine (Coq LC)® SF (Levocarnitine (Coq LC)) Sugar-Free

Oral Solution. Higher doses should be administered only with caution and only where clinical and biochemical considerations make it seem likely that higher doses will be of benefit. Dosage should start at 1 g/day, (10 mL/day), and be increased slowly while assessing tolerance and therapeutic response. Monitoring should include periodic blood chemistries, vital signs, plasma carnitine concentrations, and overall clinical condition.

Infants and children: The recommended dosage of Levocarnitine (Coq LC) is 50 to 100 mg/kg/day which is equivalent to 0.5 mL/kg/day Levocarnitine (Coq LC)® (Levocarnitine (Coq LC))

Oral Solution or Levocarnitine (Coq LC)® SF (Levocarnitine (Coq LC)) Sugar-Free

Oral Solution. Higher doses should be administered only with caution and only where clinical and biochemical considerations make it seem likely that higher doses will be of benefit. Dosage should start at 50 mg/kg/day, and be increased slowly to a maximum of 3 g/day (30 mL/day) while assessing tolerance and therapeutic response. Monitoring should include periodic blood chemistries, vital signs, plasma carnitine concentrations, and overall clinical condition.

Levocarnitine (Coq LC)® (Levocarnitine (Coq LC))

Oral Solution or Levocarnitine (Coq LC)® SF (Levocarnitine (Coq LC)) Sugar-Free

Oral Solution may be consumed alone or dissolved in drink or other liquid food. Doses should be spaced evenly throughout the day (every three or four hours) preferably during or following meals and should be consumed slowly in order to maximize tolerance.

How supplied

Levocarnitine (Coq LC)® (Levocarnitine (Coq LC)) Tablets are supplied as 330 mg tablets embossed with “Levocarnitine (Coq LC) ST” in individual blisters, packaged in boxes of 90 (NDC 54482-144-07). Store at controlled room temperature (25°C). See USP. Levocarnitine (Coq LC)® (Levocarnitine (Coq LC)) Tablets are manufactured for Sigma-Tau Pharmaceuticals, Inc. by Sigma-Tau S.p. A., 00040 Pomezia (Rome), Italy.

Levocarnitine (Coq LC)® (Levocarnitine (Coq LC))

Oral Solution

Oral Solution is manufactured for Sigma-Tau Pharmaceuticals, Inc. by: Hi-Tech Pharmacal Co., Inc. Amityville, NY 11701.

Levocarnitine (Coq LC)® SF (Levocarnitine (Coq LC)) Sugar-Free

Oral Solution

Oral Solution is manufactured for Sigma-Tau Pharmaceuticals, Inc. by: Hi-Tech Pharmacal Co., Inc. Amityville, NY 11701.

Sigma-tau Pharmaceuticals, Inc., Gaithersburg, MD 20878. Revised: April 2015.

Zinc (Coq LC) 1 mg/mL (Zinc (Coq LC) Chloride Injection, USP) contains 1 mg Zinc (Coq LC)/mL and is administered intravenously only after dilution. The additive should be diluted prior to administration in a volume of fluid not less than 100 mL. For the metabolically stable adult receiving TPN, the suggested intravenous dosage is 2.5 to 4 mg Zinc (Coq LC)/day (2.5 to 4 mL/day). An additional 2 mg Zinc (Coq LC)/day (2 mL/day) is suggested for acute catabolic states. For the stable adult with fluid loss from the small bowel, an additional 12.2 mg Zinc (Coq LC)/liter of small bowel fluid lost (12.2 mL/liter of small bowel fluid lost), or an additional 17.1 mg Zinc (Coq LC)/kg of stool or ileostomy output (17.1 mL/kg of stool or ileostomy output) is recommended. Frequent monitoring of Zinc (Coq LC) blood levels is suggested for patients receiving more than the usual maintenance dosage level of Zinc (Coq LC).

For full term infants and children up to 5 years of age, 100 mcg Zinc (Coq LC)/kg/day

(0.1 mL/kg/day) is recommended. For premature infants (birth weight less than 1500 g) up to 3 kg in body weight, 300 mcg Zinc (Coq LC)/kg/day (0.3 mL/kg/day) is suggested.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS.

How supplied

Zinc (Coq LC) 1 mg/mL (Zinc (Coq LC) Chloride Injection, USP) is supplied in 10 mL Plastic Vials (List No. 4090).

Store at 20 to 25°C (68 to 77°F).

HOSPIRA, INC., LAKE FOREST, IL 60045 USA. Revised: October, 2004

See also:
What is the most important information I should know about Levocarnitine (Coq LC)?

This medicine is contraindicated in patients with anuria, inborn errors of amino acid metabolism, especially those involving branched chain amino acid metabolism such as Maple Syrup Urine Disease and Isovaleric Acidemia, or hypersensitivity to one or more amino acids present in the solution.

Most Significant

Lactating Mother, Pregnancy, Prostatic Carcinoma, Selenium Toxicity, Wilson’s Disease

Possibly Significant

Vitamin K Deficiency Induced Hypoprothrombinemia

See also:
What is the most important information I should know about Zinc (Coq LC)?

Hypersensitivity to any of the ingredients of Zinc (Coq LC).

Use Coenzyme Q10 (Coq LC) liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Coenzyme Q10 (Coq LC) liquid daily, preferably with food.
• Dosing depends on the use and the source of the product.
• Use as directed on the package, unless instructed otherwise by your doctor.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you miss taking a dose of Coenzyme Q10 (Coq LC) liquid for 1 or more days, there is no cause for concern. If your doctor recommended that you take it, try to remember your dose every day.

Ask your health care provider any questions you may have about how to use Coenzyme Q10 (Coq LC) liquid.

Use Levocarnitine (Coq LC) solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Levocarnitine (Coq LC) solution by mouth during or after meals unless otherwise directed by your doctor.
• Levocarnitine (Coq LC) solution may be poured into drinks or liquid foods to help prevent taste changes. Finish all of the liquid.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure how to measure your dose.
• Take each dose of Levocarnitine (Coq LC) solution slowly and space your doses evenly throughout the day.
• If you miss a dose of Levocarnitine (Coq LC) solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Levocarnitine (Coq LC) solution.

Coenzyme Q10 (Coq LC) (CoQ10), also known as ubiquinone is a naturally occuring vitamin like substance found in the body. It is used as a preventive therapy for aging heart problems, and in treating heart failure, gum diseases, type 2 diabetes and high blood pressure. CoQ10 is also being used as supportive therapy for various nerve and muscle-related disorders, as well as few rare inherited disorders. CoQ10 should never be used in place of prescribed medcations for any of the above diseases, as it cannot cure these diseases when taken alone.

This medication is used to prevent and treat low blood levels of carnitine. Carnitine is a substance made in the body from meat and dairy products. It helps the body use certain chemicals (long-chain fatty acids) for energy and to keep you in good health. Low blood levels of carnitine may occur in people whose bodies cannot properly use carnitine from their diets, people on dialysis due to serious kidney disease, and people being treated with certain drugs (e.g., valproic acid, zidovudine). Carnitine levels that are too low can cause liver, heart, and muscle problems.

The injectable form of this drug is recommended if you have serious kidney disease (e.g., ESRD/dialysis) because high doses of the form taken by mouth may increase the risk of serious side effects. Consult your doctor or pharmacist for details.

How to use Levocarnitine (Coq LC) intravenous

This medication is given into a vein by slow injection or through an IV, as directed by your doctor. The dosage is based on your weight, medical condition, and response to therapy.

If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.

Inform your doctor if your condition persists or worsens.

See also:
What other drugs will affect Coenzyme Q10 (Coq LC)?

Tell your doctor if you are using any of these:

* a beta blocker blood pressure medication such as atenolol (Tenormin), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), sotalol (Betapace), and others

* a blood thinner such as warfarin (Coumadin)

* cholesterol lowering agents such as atorvastatin (Lipitor), pravastatin (Pravachol), simvastatin (Zocor), and others

* doxorubicin (Adriamycin); or

* diabetes medication.

See also:
What other drugs will affect Levocarnitine (Coq LC)?

Reports of INR increase with the use of warfarin have been observed. It is recommended that INR levels be monitored in patients on warfarin therapy after the initiation of treatment with Levocarnitine (Coq LC) or after dose adjustments.

ALPHA TOCOPHERYL/SELECTED ANTICOAGULANTS - Increased effect of the latter drug

DI-TRIVALENT CATIONS/TETRACYCLINES - Decreased effect of the latter drug

Moderate Interaction:

Assess the risk to the patient and take action as needed.

POLYVALENT CATIONS/ELTROMBOPAG - Decreased effect of the latter drug

SELECTED MINERALS/ORAL IRON SUPPLEMENTS - Decreased effect of the latter drug

DI-; TRIVALENT CATIONS/CHLOROQUINE; HYDROXYCHLOROQUINE - Decreased effect of the former drug

ORAL MULTIVALENT CATIONS/ORAL BISPHOSPHONATES - Decreased effect of the latter drug

FAT SOLUBLE VITAMINS/ORLISTAT - Decreased effect of the former drug

ORAL ZINC PRODUCTS/SELECTED ORAL QUINOLONES - Decreased effect of the latter drug

See also:
What other drugs will affect Zinc (Coq LC)?

Pyridoxine reduces the effects of levodopa (but this does not occur if a dopa decarboxylase is also given); decreases serum concentrations of phenobarbitone. Concurrent administration of drugs eg, isoniazid, penicillamine and oral contraceptives increase the requirement for pyridoxine.

Absorption of cyanocobalamin from the GIT may be reduced by neomycin, aminosalicylic acid, histamine H₂-receptor antagonists and colchicine. Serum concentrations may be decreased by concurrent administration of oral contraceptives. Many of these interactions are unlikely to be of clinical significance but should be taken into account when performing assays for blood concentrations.

Parenteral chloramphenicol may attenuate the effect of vitamin B12 in anaemia.

Folate deficiency states may be produced by a number of drugs including antiepileptics, oral contraceptives, antituberculous drugs, alcohol and folic acid antagonists eg, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides; folic acid may decrease serum-phenytoin concentrations.

There may be an increased risk of myopathy or rhabdomyolysis when nicotinic acid is used concurrently with statins. Nicotinamide may increase the requirements for insulin or oral hypoglycaemics.

Ascorbic acid may increase the absorption of iron-deficiency states.

Ascorbic acid is often given in addition to desferrioxamine to patients with iron overload (thalassemia) to achieve better iron excretion. However, early on in treatment when there is excess tissue iron, there is some evidence that ascorbic acid may worsen the iron toxicity, particularly to the heart. Thus, ascorbic acid should not be given for the first month after starting desferrioxamine treatment.

The absorption of Zinc (Coq LC) may be reduced by iron supplements, penicillamine, phosphorus-containing preparations and tetracyclines. Zinc (Coq LC) supplements reduce the absorption of copper, ciprofloxacin, iron, norfloxacin, penicillamine and tetracyclines.

See also:
What are the possible side effects of Coenzyme Q10 (Coq LC)?

Nausea, Night sweats, Pneumonitis, Abnormal breathing, Altered sperm motility, Chest pain, Constipation, Cough, Diarrhoea, Difficulty in paying attention, Fainting, Fatigue, Fungal infection of skin, Headache, Hearing loss, Heartburn, Indigestion, Influenza like symptoms, Insomnia, Rash, Itching, Loss of appetite, Low energy, Muscle pain, Respiratory tract infection, Running nose, Sinus infection, Sinus inflammation, Sore throat, Stomach pain, Stomach upset, Trembling, Vomiting

See also:
What are the possible side effects of Levocarnitine (Coq LC)?

Applies to Levocarnitine (Coq LC): capsule, powder, solution, tablet, wafer

In addition to its needed effects, some unwanted effects may be caused by Levocarnitine (Coq LC) (the active ingredient contained in Levocarnitine (Coq LC)). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Levocarnitine (Coq LC), check with your doctor or nurse as soon as possible:

More common:

• High blood pressure

• Fast heartbeat
• fever

• Seizures

Minor Side Effects

Some of the side effects that can occur with Levocarnitine (Coq LC) may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:

• Abdominal or stomach cramps
• diarrhea
• headache
• nausea or vomiting

• Abdominal discomfort
• body odor
• depression
• dizziness
• impaired vision
• loss of appetite or weight
• swelling in hands, lower legs, and feet
• tingling sensation
• weakness

Rare:

Abdominal Pain with Cramps, Back Pain, Blurred Vision, Constipation, Diarrhea, Dizziness, Dysuria, Erectile Dysfunction, Fatigue, Headache Disorder, Hypertension, Libido Changes, Nausea, Urinary Retention

See also:
What are the possible side effects of Zinc (Coq LC)?

Applies to Zinc (Coq LC) sulfate: capsules, tablets

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur while taking Zinc (Coq LC) sulfate (the active ingredient contained in Zinc (Coq LC))

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe vomiting; unusual restlessness; very dry mouth, eyes, or skin.