Coltalin-GP Extra

Each tablet also contains lactose, maize or potato starch, gelatine and magnesium stearate as excipients.

The oral/inhalation solution also contains tartaric acid and methyl parahydroxybenzoate as excipients.

The syrup also contains tartaric acid, benzoic acid, sodium carboxymethylcellulose, glycerol, sorbitol solution, pharma flavor and ethanol as excipients.

Each capsule also contains lactose, cornstarch and magnesium stearate as excipients.

Bromhexine HCl (Coltalin-GP Extra) HCl is N-cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)amine hydrochloride.

An alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used in the treatment of several disorders including asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.

Paracetamol (Coltalin-GP Extra) is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. Paracetamol (Coltalin-GP Extra) exists as small alkaline deliquescent crystals with a saline tasteacinol was introduced to medicine as a solvent for uric acid. When taken into the body the drug is partly oxidized and partly eliminated unchanged. Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successfulacinol was first introduced as an anthelmintic in 1953. A large number of piperazine compounds have anthelmintic Paracetamol (Coltalin-GP Extra). Their mode of Paracetamol (Coltalin-GP Extra) is generally by paralysing parasites, which allows the host body to easily remove or expel the invading organism.

Phenylephrine HCl (Coltalin-GP Extra) is a sympathomimetic amine that acts predominantly on α-adrenergic receptors. It is mainly used to treat nasal congestion, but may also be useful in treating hypotension and shock, hypotension during spinal anaesthesia, prolongation of spinal anaesthesia, paroxysmal supraventricular tachycardia, symptomatic relief of external or internal hemorrhoids, and to increase blood pressure as an aid in the diagnosis of heart murmurs.

Poultry: CRD, infectious bronchitis, laryngoteracheitis, infectious coryza, influenza.

Turkey: Infectious sinusitis.

Calves, pigs, lambs, kids and foals: pneumonia, bronchopneumonia, rhinitis and cough.

Temporary relief of sneezing, itchy, watery eyes, itchy nose or throat, and runny nose caused by hay fever (allergic rhinitis), or other respiratory allergies.

this medicine is indicated for symptomatic control of all allergic conditions responsive to antihistamines, including hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy, drug and serum reactions, insect bites.

Also indicated for the symptomatic relief of itch associated with chickenpox in addition to that it ca treat the allergic cough.

For systemic use of Paracetamol (Coltalin-GP Extra) Sante Naturelle: prevention and treatment of hypo- and avitaminosis of vitamin C; providing increased need for vitamin C during growth, pregnancy, lactation, with heavy loads, fatigue and during recovery after prolonged severe illness; in winter with an increased risk of infectious diseases.

For intravaginal use: chronic or recurrent vaginitis (bacterial vaginosis, nonspecific vaginitis) caused by the anaerobic flora (due to changes in pH of the vagina) in order to normalize disturbed vaginal microflora.

Phenylephrine HCl (Coltalin-GP Extra) is used for the temporary relief of stuffy nose, sinus, and ear symptoms caused by the common cold, flu, allergies, or other breathing illnesses (e.g., sinusitis, bronchitis). This medication works by decreasing swelling in the nose and ears, thereby lessening discomfort and making it easier to breathe.

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.

Relieving symptoms of sinus congestion, sinus pressure, runny nose, watery eyes, itching of the nose and throat, and sneezing due to upper respiratory infections (eg, colds), allergies, and hay fever. It may also be used for other conditions as determined by your doctor.

Chlorpheniramine maleate (Coltalin-GP Extra) is an antihistamine. It works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing.

Paracetamol (Coltalin-GP Extra) (acetaminophen) is a pain reliever and a fever reducer. The exact mechanism of Paracetamol (Coltalin-GP Extra) of is not known.

Paracetamol (Coltalin-GP Extra) is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It relieves pain in mild arthritis but has no effect on the underlying inflammation and swelling of the joint.

Paracetamol (Coltalin-GP Extra) may also be used for other purposes not listed in this medication guide.

Phenylephrine HCl (Coltalin-GP Extra) (Phenylephrine HCl (Coltalin-GP Extra)) is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Phenylephrine HCl (Coltalin-GP Extra) is used to treat nasal and sinus congestion, or congestion of the tubes that drain fluid from your inner ears, called the eustachian (yoo-STAY-shun) tubes.

Phenylephrine HCl (Coltalin-GP Extra) may also be used for purposes not listed in this medication guide.

Unless otherwise prescribed, the following doses are recommended:

Tablet: Adults and Children >12 years: 8 mg (1 tab) thrice daily; 6-12 years: 4 mg (½ tab) thrice daily; 2-6 years: 4 mg (½ tab) twice daily.

Oral Solution:

Inhalation Solution (with aerosol apparatus): It is generally recommended to warm inhalation solution to body temperature before inhalation. Patients with bronchial asthma may be advised to commencing inhalation after they have taken their regular bronchospasmolytic therapy.

Adults: 4 mL. Children >12 years: 2 mL; 6-12 years: 1 mL; 2-6 years: 10 drops; <2 years: 5 drops. All doses to be taken twice daily.

The solution may be diluted 1:1 in physiological saline solution. In order to avoid precipitation, the solution should be inhaled immediately after mixing. The combined administration of inhalation and oral application intensifies the effect, and is especially suited for the commencement of treatment in cases where the full effect is to be reached quickly.

Syrup: Adults and Children >12 years: 5 ml (1 tsp) thrice daily.

At commencement of treatment, it may be necessary to increase the total daily dose up to 48 mg in adults.

The syrup is sugar-free and therefore suitable for diabetics and small children.

Ampoule: Severe cases, before and after surgical intervention: 1 amp SC, IM or IV (duration of injection: 2-3 min) 2-3 times daily.

Capsule: Adults: 1 cap 3 times daily.

It is recommended for the initial phase of treatment usually lasting not more than a week.

Patients being treated with Bromhexine HCl (Coltalin-GP Extra) should be notified of an expected increase in the flow of secretions.

Tab Adult & childn >12 yr 1 tab tds-qds. Childn 6-12 yr ½ tab tds-qds. Syr Adult 5 mL tds-qds. Childn 6-12 yr 2.5 mL tds-qds, 2-5 yr 1.25 mL tds-qds.

Adult 10 drops. Childn 6-12 yr 5 drops. Infant 2 drops. To be taken 3-4 times daily.

Usual Adult Paracetamol (Coltalin-GP Extra) Dose for Fever:

General Dosing Guidelines: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours orally or rectally.

Paracetamol (Coltalin-GP Extra) 500mg tablets: Two 500 mg tablets orally every 4 to 6 hours

Usual Adult Paracetamol (Coltalin-GP Extra) Dose for Pain:

General Dosing Guidelines: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours orally or rectally.

Paracetamol (Coltalin-GP Extra) 500mg tablets: Two 500 mg tablets orally every 4 to 6 hours

Usual Pediatric Dose for Fever:

Oral or Rectal:

<=1 month: 10 to 15 mg/kg/dose every 6 to 8 hours as needed.

>1 month to 12 years: 10 to 15 mg/kg/dose every 4 to 6 hours as needed (Maximum: 5 doses in 24 hours)

Fever: 4 months to 9 years: Initial Dose: 30 mg/kg (Reported by one study (n=121) to be more effective in reducing fever than a 15 mg/kg maintenance dose with no difference regarding clinical tolerance.)

>=12 years: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours.

Usual Pediatric Dose for Pain:

Oral or Rectal:

<=1 month: 10 to 15 mg/kg/dose every 6 to 8 hours as needed.

>1 month to 12 years: 10 to 15 mg/kg/dose every 4 to 6 hours as needed (Maximum: 5 doses in 24 hours)

Fever: 4 months to 9 years: Initial Dose: 30 mg/kg (Reported by one study (n=121) to be more effective in reducing fever than a 15 mg/kg maintenance dose with no difference regarding clinical tolerance.)

>=12 years: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours.

Usual Adult Dose for Hypotension:

IM or subcutaneous: 2 to 5 mg every 1 to 2 hours as needed.

IV bolus: 0.2 mg/dose (range: 0.1 to 0.5 mg/dose) every 10 to 15 minutes as needed (initial dose should not exceed 0.5 mg)

IV infusion: 100 to 180 mcg/min initially. The usual maintenance dose is 40 to 60 mcg/min.

Alternatively, 0.5 mcg/kg/minute; titrate to desired response. Dosing ranges between 0.4 to 9.1 mcg/kg/minute have been reported.

Usual Adult Dose for Shock:

IM or subcutaneous: 2 to 5 mg every 1 to 2 hours as needed.

IV bolus: 0.2 mg/dose (range: 0.1 to 0.5 mg/dose) every 10 to 15 minutes as needed (initial dose should not exceed 0.5 mg)

IV infusion: 100 to 180 mcg/min initially. The usual maintenance dose is 40 to 60 mcg/min.

Alternatively, 0.5 mcg/kg/minute; titrate to desired response. Dosing ranges between 0.4 to 9.1 mcg/kg/minute have been reported.

Usual Adult Dose for Supraventricular Tachycardia:

0.25 to 0.5 mg IV over 30 seconds.

Usual Adult Dose for Nasal Congestion:

Tablets or oral liquid: 10 to 20 mg orally every 4 hours as needed.

Phenylephrine HCl (Coltalin-GP Extra) 7.5 mg/5 mL oral liquid:

15 mg orally every 6 hours not to exceed 60 mg daily.

Phenylephrine HCl (Coltalin-GP Extra) 10 mg oral tablet:

10 mg orally every 4 to 6 hours not to exceed 4 doses daily.

Phenylephrine HCl (Coltalin-GP Extra) 10 mg oral disintegrating strip:

10 mg orally every 4 hours not to exceed 6 doses daily.

Phenylephrine HCl (Coltalin-GP Extra) 10 mg/5 mL oral suspension, extended release:

10 to 20 mg orally every 12 hours.

Phenylephrine HCl (Coltalin-GP Extra) tannate 10 mg oral tablet, chewable, extended release:

10 to 20 mg orally every 12 hours.

Phenylephrine HCl (Coltalin-GP Extra) tannate 7.5 mg/5 mL oral suspension, extended release

7.5 to 15 mg orally every 12 hours.

Usual Pediatric Dose for Hypotension:

IM or subcutaneous: 0.1 mg/kg every 1 to 2 hours as needed. Maximum dose: 5 mg.

IV bolus: 5 to 20 mcg/kg/dose every 10 to 15 minutes as needed.

IV: 0.1 to 0.5 mcg/kg/min titrated to effect.

Usual Pediatric Dose for Shock:

IM or subcutaneous: 0.1 mg/kg every 1 to 2 hours as needed. Maximum dose: 5 mg.

IV bolus: 5 to 20 mcg/kg/dose every 10 to 15 minutes as needed.

IV: 0.1 to 0.5 mcg/kg/min titrated to effect.

Usual Pediatric Dose for Supraventricular Tachycardia:

5 to 10 mcg/kg IV over 30 seconds.

Usual Pediatric Dose for Nasal Congestion:

Phenylephrine HCl (Coltalin-GP Extra) 1.25 mg/0.8 mL oral liquid:

2 years to 5 years: 1.6 mL orally every 4 hours not to exceed 6 doses daily.

Chewable tablets or oral liquid:

6 years to 11 years: 10 mg orally every 4 hours as needed.

12 years or older: 10 to 20 mg orally every 4 hours as needed.

Phenylephrine HCl (Coltalin-GP Extra) 7.5 mg/5 mL oral liquid:

2 years to 5 years: 3.75 mg orally every 6 hours not to exceed 15 mg daily.

6 years to 11 years: 7.5 mg orally every 6 hours not to exceed 30 mg daily.

12 years or older: 15 mg orally every 6 hours not to exceed 60 mg daily.

Phenylephrine HCl (Coltalin-GP Extra) 10 mg oral tablet:

12 years or older: 10 mg orally every 4 to 6 hours not to exceed 4 doses daily.

Phenylephrine HCl (Coltalin-GP Extra) 10 mg oral tablet, disintegrating:

2 years to 5 years: 5 mg orally every 4 hours as needed.

6 years to 11 years: 10 mg orally every 4 hours as needed.

12 years or older: 10 to 20 mg orally every 4 hours as needed.

Phenylephrine HCl (Coltalin-GP Extra) 10 mg/5 mL oral suspension, extended release:

12 years or older: 10 to 20 mg orally every 12 hours.

6 years to 11 years: 5 to 10 mg orally every 12 hours.

Phenylephrine HCl (Coltalin-GP Extra) 10 mg oral disintegrating strip:

12 years or older: 10 mg orally every 4 hours not to exceed 6 doses daily.

Phenylephrine HCl (Coltalin-GP Extra) tannate 10 mg oral tablet, chewable, extended release:

6 years to 11 years: 5 to 10 mg orally every 12 hours.

12 years or older: 10 to 20 mg orally every 12 hours.

Phenylephrine HCl (Coltalin-GP Extra) tannate 7.5 mg/5 mL oral suspension, extended release

2 years to 5 years: 1.25 to 2.5 mL orally every 12 hours.

6 years to 11 years: 2.5 to 5 mL orally every 12 hours.

12 years or older: 5 to 10 mL orally every 12 hours.

Phenylephrine HCl (Coltalin-GP Extra) 1.25 mg oral disintegrating strip:

2 years to 3 years: 2.5 mg orally every 4 hours, not to exceed 15 mg in 24 hours.

Phenylephrine HCl (Coltalin-GP Extra) 2.5 mg oral disintegrating strip:

2 years to 5 years: 2.5 mg orally every 4 hours, not to exceed 15 mg in 24 hours.

6 years to 11 years: 5 mg orally every 4 hours, not to exceed 30 mg in 24 hours.

Phenylephrine HCl (Coltalin-GP Extra) 1.25 mg oral tablet, chewable:

12 years or older: 5 mg orally every 4 hours not to exceed 6 doses daily.

Phenylephrine HCl (Coltalin-GP Extra) 2.5 mg/5 mL oral liquid:

4 years to 5 years: 5 mL orally every 4 hours, not to exceed 6 doses in 24 hours.

6 years to 11 years: 10 mL orally every 4 hours, not to exceed 6 doses in 24 hours.

Bromhexine HCl (Coltalin-GP Extra) hydrochloride SYRUP is contra-indicated in patients with known hypersensitivity to sympathomimetic amines or any of the other ingredients; hypertrophic obstructive cardiomyopathy; and tachyarrhythmia.

Sympathomimetics, such as orciprenaline sulphate, may interact with monoamine oxidase inhibitors (MAOI), and therefore Bromhexine HCl (Coltalin-GP Extra) hydrochloride SYRUP should not be given to patients receiving such treatment or within 14 days of MAOI treatment termination.

Safety in pregnancy and lactation has not been established.

See also:
What is the most important information I should know about Chlorpheniramine maleate (Coltalin-GP Extra)?

Hypersensitivity to antihistamines; narrow-angle glaucoma; stenosing peptic ulcer; symptomatic prostatic hypertrophy; asthmatic attack; bladder neck obstruction; pyloroduodenal obstruction; MAO therapy; use in newborn or premature infants and in breast-feeding mothers.

Intolerance to Noscapine (Coltalin-GP Extra).

Pregnancy.

See also:
What is the most important information I should know about Paracetamol (Coltalin-GP Extra)?

Paracetamol (Coltalin-GP Extra) should not be used in patients who have previously exhibited hypersensitivity to aspirin and/or nonsteroidal antiinflammatory agents. Paracetamol (Coltalin-GP Extra) should not be given to patients with a recent history of gastrointestinal bleeding or in patients with bleeding disorders (e.g., hemophilia).

See also:
What is the most important information I should know about Phenylephrine HCl (Coltalin-GP Extra)?

Hypersensitivity to any component of the products, potassium guaiacolsulfonate, or to sympathomimetic amines; severe hypertension; ventricular tachycardia; pheochromocytoma; ophthalmic 10% solution contraindicated in infants and patients with aneurysms; low birth weight infants; anatomically narrow angles or narrow-angle glaucoma; during intraocular procedures when the corneal epithelial barrier has been disrupted; elderly patients with severe arteriosclerotic CV or cerebrovascular disease; MAOI use or 14 days after stopping an MAOI; severe coronary artery disease.

Use Chlorpheniramine maleate (Coltalin-GP Extra) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Chlorpheniramine maleate (Coltalin-GP Extra) may be taken with or without food.
• Shake well before using.
• Use the dropper that comes with Chlorpheniramine maleate (Coltalin-GP Extra) to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you miss a dose of Chlorpheniramine maleate (Coltalin-GP Extra), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Chlorpheniramine maleate (Coltalin-GP Extra).

Use Paracetamol (Coltalin-GP Extra) exactly as directed on the label, or as prescribed by your doctor.

Do not use more of this medication than is recommended. An overdose of Paracetamol (Coltalin-GP Extra) can cause serious harm. The maximum amount for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Using more Paracetamol (Coltalin-GP Extra) could cause damage to your liver. If you drink more than three alcoholic beverages per day, talk to your doctor before taking Paracetamol (Coltalin-GP Extra) and never use more than 2 grams (2000 mg) per day. If you are treating a child, use a pediatric form of Paracetamol (Coltalin-GP Extra). Carefully follow the dosing directions on the medicine label. Do not give the medication to a child younger than 2 years old without the advice of a doctor.

Measure the liquid form of Paracetamol (Coltalin-GP Extra) with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. You may need to shake the liquid before each use. Follow the directions on the medicine label.

The Paracetamol (Coltalin-GP Extra) chewable tablet must be chewed thoroughly before you swallow it.

Make sure your hands are dry when handling the Paracetamol (Coltalin-GP Extra) disintegrating tablet. Place the tablet on your tongue. It will begin to dissolve right away. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

To use the Paracetamol (Coltalin-GP Extra) effervescent granules, dissolve one packet of the granules in at least 4 ounces of water. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

Do not take a Paracetamol (Coltalin-GP Extra) rectal suppository by mouth. It is for use only in your rectum. Wash your hands before and after inserting the suppository.

Try to empty your bowel and bladder just before using the Paracetamol (Coltalin-GP Extra) suppository. Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.

For best results from the suppository, lie down and insert the suppository pointed tip first into the rectum. Hold in the suppository for a few minutes. It will melt quickly once inserted and you should feel little or no discomfort while holding it in. Avoid using the bathroom just after inserting the suppository.

Stop using Paracetamol (Coltalin-GP Extra) and call your doctor if:

• you still have a fever after 3 days of use;

• you still have pain after 7 days of use (or 5 days if treating a child);

• you have a skin rash, ongoing headache, or any redness or swelling; or

• if your symptoms get worse, or if you have any new symptoms.

Urine glucose tests may produce false results while you are taking Paracetamol (Coltalin-GP Extra). Talk to your doctor if you are diabetic and you notice changes in your glucose levels during treatment.

Store Paracetamol (Coltalin-GP Extra) at room temperature away from heat and moisture. The rectal suppositories can be stored at room temperature or in the refrigerator.

Use Phenylephrine HCl (Coltalin-GP Extra) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Phenylephrine HCl (Coltalin-GP Extra) is for use in the eye only. Avoid contact with the nose or mouth.
• To use Phenylephrine HCl (Coltalin-GP Extra), first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
• To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
• Do not wear contact lenses while you are using Phenylephrine HCl (Coltalin-GP Extra). Sterilize contact lenses according to the manufacturer's directions and check with your doctor before using them.
• Do not use Phenylephrine HCl (Coltalin-GP Extra) if it is brown or contains particles.
• If you miss a dose of Phenylephrine HCl (Coltalin-GP Extra), use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Phenylephrine HCl (Coltalin-GP Extra).

Bromhexine HCl (Coltalin-GP Extra) is used to treat breathing difficulties caused by excessive mucus secretions in the air passages associated with respiratory tract infections.

This medication is used to treat itching and pain caused by minor burns/cuts/scrapes, sunburn, insect bites, minor skin irritations, or rashes from poison ivy, poison oak, or poison sumac.

Diphenhydramine belongs to a class of drugs known as antihistamines. It works by preventing the effects of a certain natural substance (histamine) that causes itching. Calamine helps to dry the oozing and weeping caused by irritation from poisonous plants.

Use of this medication is not recommended in children younger than 2 years unless directed by the doctor.

How to use Chlorpheniramine maleate (Coltalin-GP Extra) topical

Use this medication on the skin only. Some products may need to be shaken well before use. Follow all directions on the product package, or use as directed by your doctor. Before applying, clean the affected area with soap and water. Gently pat dry. Apply to the affected area as directed, usually 3 to 4 times a day. Wash hands immediately after use, unless the area being treated includes the hands.

Do not use on large areas of the body or apply more often than directed. Do not use on chickenpox or measles. Do not use with other products that contain diphenhydramine (e.g., allergy medication taken by mouth). Your condition will not clear faster, but side effects may be increased.

Avoid getting the product in your eyes, nose, ears, or mouth. If the medication gets in these areas, rinse the area right away with clean water.

Tell your doctor if your condition persists or worsens after 7 days of treatment. If you think you may have a serious medical problem, seek immediate medical attention.

Noscapine (Coltalin-GP Extra) is used to treat cough, asthma or emphysema (lung disease).

This drug is used to treat mild to moderate pain (from headaches, menstrual periods, toothaches, backaches, osteoarthritis, or cold/flu aches and pains) and to reduce fever.

How to use Paracetamol (Coltalin-GP Extra)

Take this product by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

There are many brands and forms of acetaminophen available. Read the dosing instructions carefully for each product because the amount of acetaminophen may be different between products. Do not take more acetaminophen than recommended.

If you are giving acetaminophen to a child, be sure you use a product that is meant for children. Use your child's weight to find the right dose on the product package. If you don't know your child's weight, you can use their age.

For suspensions, shake the medication well before each dose. Some liquids do not need to be shaken before use. Follow all directions on the product package. Measure the liquid medication with the provided dose-measuring spoon/dropper/syringe to make sure you have the correct dose. Do not use a household spoon.

For rapidly-dissolving tablets, chew or allow to dissolve on the tongue, then swallow with or without water. For chewable tablets, chew thoroughly before swallowing.

Do not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

For effervescent tablets, dissolve the dose in the recommended amount of water, then drink.

Pain medications work best if they are used as the first signs of pain occur. If you wait until the symptoms have worsened, the medication may not work as well.

Do not take this medication for fever for more than 3 days unless directed by your doctor. For adults, do not take this product for pain for more than 10 days (5 days in children) unless directed by your doctor. If the child has a sore throat (especially with high fever, headache, or nausea/vomiting), consult the doctor promptly.

Tell your doctor if your condition persists or worsens or if you develop new symptoms. If you think you may have a serious medical problem, get medical help right away.

Phenylephrine HCl (Coltalin-GP Extra) is used for the temporary relief of stuffy nose, sinus, and ear symptoms caused by the common cold, flu, allergies, or other breathing illnesses (e.g., sinusitis, bronchitis). This medication works by decreasing swelling in the nose and ears, thereby lessening discomfort and making it easier to breathe.

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.

These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

How to use Phenylephrine HCl (Coltalin-GP Extra)

If you are using the over-the-counter product, read and follow all directions on the product package before taking this medication.

Take this medication by mouth with or without food or as directed by your doctor. Taking it with food may decrease stomach upset.

If you are using the liquid, carefully measure your prescribed dose using a medication-measuring device or spoon. Do not use a household spoon because you may not get the correct dose.

If you are using chewable tablets, chew each tablet thoroughly before swallowing.

If you are using a product made to dissolve in the mouth (tablets or strips), dry your hands before handling the medication. Place each dose on the tongue and allow to dissolve completely, then swallow it with saliva or with water.

The dosage is based on your age. Do not increase your dose or take this medication more often than directed without your doctor's approval. Improper use (abuse) of this medication may result in serious harm (e.g., hallucinations, seizure, death).

If your symptoms worsen or do not improve after 7 days, if you develop fever/chills, or if you think you may have a serious medical problem, seek immediate medical attention.

A reduction in dose of cardiac glycosides (e.g. digitalis) and quinidine might become necessary in patients suffering from congestive cardiac failure because of the positive inotropic effect of orciprenaline sulphate.

Bromhexine HCl (Coltalin-GP Extra) hydrochloride SYRUP should not be administered concomitantly with beta-blocking agents, due to orciprenaline’s reversal of anti-hypertensive action.

The concomitant use of other sympathomimetic agents should be carefully controlled to avoid potentiation of effects.

See also:
What other drugs will affect Chlorpheniramine maleate (Coltalin-GP Extra)?

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), antispasmodics (e.g., atropine, belladonna alkaloids), drugs for Parkinson's disease (e.g., anticholinergics such as benztropine, trihexyphenidyl), scopolamine, tricyclic antidepressants (e.g., amitriptyline).

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

Chlorpheniramine is very similar to dexchlorpheniramine. Do not use medications containing dexchlorpheniramine while using chlorpheniramine.

This medication may interfere with certain laboratory tests (including allergy skin testing), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Noscapine (Coltalin-GP Extra) should not be given concomitantly with other C.N.S. depressants or alcohol

See also:
What other drugs will affect Paracetamol (Coltalin-GP Extra)?

With the simultaneous use with inducers of microsomal liver enzymes, means having hepatotoxic effect, increasing the risk of hepatotoxic Paracetamol (Coltalin-GP Extra) of Paracetamol (Coltalin-GP Extra).

With the simultaneous use of anticoagulants may be slight to moderate increase in prothrombin time.

With the simultaneous use of anticholinergics may decrease absorption of Paracetamol (Coltalin-GP Extra).

With the simultaneous use of oral contraceptives accelerated excretion of Paracetamol (Coltalin-GP Extra) from the body and may reduce its analgesic Paracetamol (Coltalin-GP Extra).

With the simultaneous use with urological means reduced their effectiveness.

With the simultaneous use of activated charcoal reduced bioavailability of Paracetamol (Coltalin-GP Extra).

When Paracetamol (Coltalin-GP Extra) Guardian applied simultaneously with diazepam may decrease excretion of diazepam.

There have been reports about the possibility of enhancing mielodepression effect of zidovudine while applying with Paracetamol (Coltalin-GP Extra). A case of severe toxic liver injury.

Described cases of toxic effects of Paracetamol (Coltalin-GP Extra), while the use of isoniazid.

When applied simultaneously with carbamazepine, phenytoin, phenobarbital, primidonom decreases the effectiveness of Paracetamol (Coltalin-GP Extra), which is caused by an increase in its metabolism and excretion from the body. Cases of hepatotoxicity, while the use of Paracetamol (Coltalin-GP Extra) and phenobarbital.

In applying cholestyramine a period of less than 1 h after administration of Paracetamol (Coltalin-GP Extra) may decrease of its absorption.

At simultaneous application with lamotrigine moderately increased excretion of lamotrigine from the body.

With the simultaneous use of metoclopramide may increase absorption of Paracetamol (Coltalin-GP Extra) and its increased concentration in blood plasma.

When applied simultaneously with probenecid may decrease clearance of Paracetamol (Coltalin-GP Extra), with rifampicin, sulfinpyrazone - may increase clearance of Paracetamol (Coltalin-GP Extra) due to increasing its metabolism in the liver.

At simultaneous application of Paracetamol (Coltalin-GP Extra) Guardian with ethinylestradiol increases absorption of Paracetamol (Coltalin-GP Extra) from the gut.

Enhances the effect of indirect anticoagulants (coumarin derivatives and indandione). Antipyretic and analgesic activity of caffeine increases, reduce - rifampicin, phenobarbital and alcohol (accelerated biotransformation, inducing microsomal liver enzymes).

See also:
What other drugs will affect Phenylephrine HCl (Coltalin-GP Extra)?

If you are taking this product under your doctor's direction, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication.

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting the nasal decongestant.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: high blood pressure medications (e.g., reserpine, guanethidine), tricyclic antidepressants (e.g., amitriptyline).

Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain decongestants or ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about using those products safely.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Bromhexine HCl (Coltalin-GP Extra)’s pharmacological action may lead to gastric irritation. A transient rise in serum aminotransferase values have been reported due to Bromhexine HCl (Coltalin-GP Extra).

Orciprenaline sulphate, as a sympathomimetic agent, may precipitate a wide range of adverse effects. Side-effects include fear; anxiety, restlessness, tremor, insomnia, confusion, irritability, weakness and psychotic states. Appetite may be reduced and nausea and vomiting may occur. A rise in blood pressure which may produce cerebral haemorrhage and pulmonary oedema, tachycardia and cardiac arrhythmias, anginal pain, palpitations, and cardiac arrest. Hypotension with dizziness and fainting and flushing may occur. Other effects that may occur include difficulty in micturition and urinary retention; dyspnoea; weakness; headache; disturbances of glucose metabolism; sweating and hypersalivation. Muscle cramps or twitching or unpleasant taste may occur.

See also:
What are the possible side effects of Chlorpheniramine maleate (Coltalin-GP Extra)?

Drowsiness, dizziness, headache, constipation, stomach upset, blurred vision, decreased coordination, or dry mouth/nose/throat may occur. These effects may decrease as your body adjusts to the medication. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.

To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute. Chlorpheniramine can dry up and thicken mucus in your lungs, making it more difficult to breathe and clear your lungs. To help prevent this effect, drink plenty of fluids unless otherwise directed by your doctor.

If you are using a sustained-release product, an empty tablet shell may appear in your stool. This is harmless.

If your doctor has prescribed this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: mental/mood changes (e.g., hallucinations, irritability, nervousness, confusion), ringing in the ears, trouble urinating.

Tell your doctor right away if any of these rare but very serious side effects occur: easy bruising/bleeding, fast/irregular heartbeat, seizure.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

CNS depression, sedation, drowsiness, lassitude, dizziness. GI upsets, anorexia, or increased appetite, epigastric pain, blurring of vision, dysuria, dryness of mouth, tightness in chest, hypotension, muscular weakness, tinnitus, euphoria, headache, paradoxical CNS stimulation.

Potentially Fatal: CV collapse and respiratory failure and there is also the side effects of corticosteroids if included.

See also:
What are the possible side effects of Paracetamol (Coltalin-GP Extra)?

Effects due to the presence of acetylsalicylic acid.

Accidents awareness with respiratory or skin reactions (angioedema, urticaria, asthma, anaphylactic shock);

Cross hypersensitivity reactions with NSAIDs and with tartrazine;

At low doses recommended for the use of Paracetamol (Coltalin-GP Extra), side effects of aspirin are generally limited to some irritation of the gastro-intestinal tract.

At higher doses, side effects include gastrointestinal mucosal erosions, gastric ulcer or duodenal ulcer, occult blood loss, melena.

Acetylsalicylic acid may also increase the tendency to bleeding and bleeding time (the lengthening of bleeding continues 4-6 days after stopping the drug).

It may also worsen renal function including cases of pre-existing condition (the long-term use can cause chronic kidney disease).

The signs of salicylic overdose described under.

Effects due to the presence of Paracetamol (Coltalin-GP Extra).

At the doses and duration of recommended treatment, side effects are usually negligible, but the prolonged use of Paracetamol (Coltalin-GP Extra) in therapeutic doses large (2-4 g per day, or 10-20 tablets Paracetamol (Coltalin-GP Extra)) may cause the appearance chronic hepatitis. This justifies the recommendations of caution especially in patients with liver disease prior.

Very rarely, it can produce thrombocytopenia.

The acute liver toxicity in overdose massive (doses greater than 8 g of Paracetamol (Coltalin-GP Extra)) is described in paragraph overdose.

See also:
What are the possible side effects of Phenylephrine HCl (Coltalin-GP Extra)?

Mild upset stomach, trouble sleeping, dizziness, lightheadedness, headache, nervousness, shaking, or fast heartbeat may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

This product may reduce blood flow to your hands or feet, causing them to feel cold. Smoking may worsen this effect. Dress warmly and avoid tobacco use.

If your doctor has directed you to take this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: fast/irregular heartbeat, severe/uncontrolled shaking, difficulty urinating.

Tell your doctor right away if any of these rare but very serious side effects occur: seizures, mental/mood changes (e.g., anxiety, panic, confusion, unusual thoughts/behavior).

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.