Cinnarizine/Dimenhydrinate

Intermittent claudication; Ischaemic heart disease; Prevention of thrombotic stroke,Prevention of subacute stent occlusion after intracoronary stenting.

Adult & elderly 1 tab tid.

* People with severely decreased kidney function.

* People with severely decreased liver function.

* Closed angle glaucoma.

* People with increased pressure in the brain (raised intracranial pressure).

* People who are intoxicated with alcohol (acute alcoholism).

* Convulsions, eg epilepsy.

* People with difficulty passing urine (urinary retention), due to prostate problems.

* Pregnancy.

* Breastfeeding.

* This medicine is not recommended for children and adolescents under 18 years of age, as there is no information regarding its safety and efficacy in this age group.

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.

If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

* The safety of this medicine for use during pregnancy has not been established. It should not be used by pregnant women. Seek medical advice from your doctor.

* This medicine may pass into breast milk and could have unwanted effects on a nursing infant. For this reason it should not be used by women who are breastfeeding. Seek medical advice from your doctor.

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.

There will be increased drowsiness and sedation if this medicine is taken in combination with any of the following (which can also cause drowsiness):

* alcohol

* antipsychotics, eg haloperidol

* barbiturates, eg phenobarbital, amobarbital

* benzodiazepines, eg diazepam, temazepam

* MAOI antidepressants, eg phenelzine, isocarboxazid or tranylcypromine

* other sedating antihistamines, eg chlorphenamine, hydroxyzine

* sleeping tablets, eg zopiclone

* strong opioid painkillers, eg codeine, dihydrocodeine, morphine

* tricyclic antidepressants, eg amitriptyline.

There may be an increased risk of side effects such as dry mouth, blurred vision, urine retention and constipation if this medicine is taken with anticholinergic medicines that can cause this type of side effect, such as the following:

* anticholinergic medicines for Parkinson’s symptoms, eg procyclidine, orphenadrine, trihexyphenidyl

* anticholinergic medicines for urinary incontinence, eg tolterodine, oxybutynin

* antipsychotics, eg chlorpromazine, clozapine

* antispasmodics, eg hyoscine, atropine

* MAOI antidepressants, eg phenelzine, isocarboxazid or tranylcypromine

* tricyclic antidepressants, eg amitriptyline, imipramine.

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.