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Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 15.03.2022
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N 0071–3070–07
Chloromycetin Ophthalmic Ointment, 1% (Chloramphenicol Ophthalmic Ointment, USP) is supplied, sterile, in ophthalmic ointment tubes of 3.5 grams.
Chloromycetin, brand of chloramphenicol. Reg US Pat Off Caution—Federal law prohibits dispensing without prescription.
Manufactured by: PARKE-DAVIS Div of Warner-Lambert Co/Morris Plains, NJ 07950 USA. Revised: October 2006.
Chloramphenicol should be used only in those serious infections for which less potentially dangerous drugs are ineffective or contraindicated. Bacteriological studies should be performed to determine the causative organisms and their sensitivity to chloramphenicol (see BOX WARNING).
Chloromycetin Ophthalmic Ointment, 1% (Chloramphenicol Ophthalmic Ointment, USP) is indicated for the treatment of surface ocular infections involving the conjunctiva and/or cornea caused by chloramphenicol-susceptible organisms.
The particular antiinfective drug in this product is active against the following common bacterial eye pathogens:
Staphylococcus aureus
Streptococcus, including Streptococcus pneumoniae
Escherichia coli
Haemophilus influenzae
Klebsiella/Enterobacter species
Moraxella lucunata (Morax-Axenfeld bacillus)
Neisseria species
This product does not provide adequate coverage against:
Pseudomonas aeruginosa
Serratia marcescens
A small amount of ointment placed in the lower conjunctival sac every three hours, or more frequently if deemed advisable by the prescribing physician. Administration should be continued day and night the first 48 hours, after which the interval between applications may be increased. Treatment should be continued for at least 48 hours after the eye appears normal.
This product is contraindicated in persons sensitive to any of its components.
WARNINGS
SEE BOX WARNING
Ophthalmic ointments may retard corneal wound healing.
PRECAUTIONS
The prolonged use of antibiotics may occasionally result in overgrowth of nonsusceptible organisms including fungi. If new infections appear during medication, the drug should be discontinued and appropriate measures should be taken.
In all serious infections the topical use of chloramphenicol should be supplemented by appropriate systemic medication.
SIDE EFFECTS
Blood dyscrasias have been reported in association with the use of chloramphenicol (see WARNINGS).
Allergic or inflammatory reactions due to individual hypersensitivity and occasional burning or stinging may occur with the use of Chloromycetin Ophthalmic Ointment.
DRUG INTERACTIONS
No Information Provided
Blood dyscrasias have been reported in association with the use of chloramphenicol (see WARNINGS).
Allergic or inflammatory reactions due to individual hypersensitivity and occasional burning or stinging may occur with the use of Chloromycetin Ophthalmic Ointment.
No Information Provided
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