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Medically reviewed by Oliinyk Elizabeth Ivanovna, PharmD. Last updated on 28.06.2022
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Top 20 medicines with the same components:
used to treat symptoms caused by the common cold, flu, allergies, hay fever, or other breathing illnesses (e.g., sinusitis, bronchitis). Dextromethorphan (Certuss-D) is a cough suppressant that affects a certain part of the brain (cough center), reducing the urge to cough. Decongestants help relieve stuffy nose symptoms. Antihistamines relieve watery eyes, itchy eyes/nose/throat, runny nose, and sneezing.
There are many brands and forms of Certuss-D (Phenylephrine (Certuss-D)) available. Not all brands are listed on this leaflet.
Dextromethorphan (Certuss-D) is a cough suppressant that affects signals in the brain that trigger cough reflex.
Guaifenesin (Certuss-D) is an expectorant that loosens congestion in your chest and throat.
Phenylephrine (Certuss-D) is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
Certuss-D (Phenylephrine (Certuss-D)) is a combination medicine used to treat cough, stuffy nose, and chest congestion caused by allergies, the common cold, or the flu.
This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.
Certuss-D (Phenylephrine (Certuss-D)) may also be used for purposes not listed in this medication guide.
Usual Adult Dose for Cough and Nasal Congestion:
Dextromethorphan (Certuss-D) 15 mg/Guaifenesin (Certuss-D) 100 mg/Phenylephrine (Certuss-D) 5 mg/5 mL:
10 mL orally every 6 hours not to exceed 40 mL daily.
Dextromethorphan (Certuss-D) 15 mg/Guaifenesin (Certuss-D) 300 mg/Phenylephrine (Certuss-D) 10 mg/5 mL:
10 mL orally every 6 hours not to exceed 40 mL daily.
Dextromethorphan (Certuss-D) 20 mg/Guaifenesin (Certuss-D) 100 mg/Phenylephrine (Certuss-D) 10 mg/5 mL:
5 mL orally every 4 to 6 hours not to exceed 30 mL daily.
Dextromethorphan (Certuss-D) 20 mg/Guaifenesin (Certuss-D) 200 mg/Phenylephrine (Certuss-D) 5 mg/5 mL:
10 mL orally every 8 hours not to exceed 30 mL daily
Dextromethorphan (Certuss-D) 20 mg/Guaifenesin (Certuss-D) 800 mg/Phenylephrine (Certuss-D) 20 mg oral tablets, extended release:
1 to 1.5 tablets orally every 12 hours not to exceed 3 tablets daily.
Dextromethorphan (Certuss-D) 28 mg/Guaifenesin (Certuss-D) 388 mg/Phenylephrine (Certuss-D) 10 mg oral tablets:
1 tablet orally every 4 hours not to exceed 6 tablets in 24 hours
Dextromethorphan (Certuss-D) 28 mg/Guaifenesin (Certuss-D) 388 mg/Phenylephrine (Certuss-D) 10 mg /5 mL oral liquid:
5 mL orally every 6 to 8 hours not to exceed 4 doses 24 hours
Dextromethorphan (Certuss-D) 30 mg/Guaifenesin (Certuss-D) 900 mg/Phenylephrine (Certuss-D) 30 mg oral tablets, extended release:
1 tablet orally every 12 hours not to exceed 2 tablets daily.
Dextromethorphan (Certuss-D) 25 mg/Guaifenesin (Certuss-D) 175 mg/Phenylephrine (Certuss-D) 12.5 mg/5 mL:
5 mL orally four times daily.
Dextromethorphan (Certuss-D) 25 mg/Guaifenesin (Certuss-D) 550 mg/Phenylephrine (Certuss-D) 20 mg oral tablets, and Dextromethorphan (Certuss-D) 25 mg/Guaifenesin (Certuss-D) 600 mg/Phenylephrine (Certuss-D) 20 mg oral tablets, extended release:
1 to 2 tablets orally every 12 hours not to exceed 3 tablets daily.
Dextromethorphan (Certuss-D) 30 mg/Guaifenesin (Certuss-D) 1000 mg/Phenylephrine (Certuss-D) 20 mg oral tablets, extended release:
1 tablet orally every 12 hours not to exceed 2 tablets daily.
Dextromethorphan (Certuss-D) 30 mg/Guaifenesin (Certuss-D) 1200 mg/Phenylephrine (Certuss-D) 30 mg oral tablets, extended release:
1 tablet orally every 12 hours not to exceed 2 tablets daily.
Dextromethorphan (Certuss-D) 30 mg/Guaifenesin (Certuss-D) 600 mg/Phenylephrine (Certuss-D) 10 mg oral tablets, extended release:
1 to 2 tablets orally every 12 hours not to exceed 4 tablets daily.
Dextromethorphan (Certuss-D) 40 mg/Guaifenesin (Certuss-D) 200 mg/Phenylephrine (Certuss-D) 20 mg/10 mL extended release suspension:
10 mL orally every 12 hours not to exceed 2 doses daily.
Dextromethorphan (Certuss-D) 45 mg/Guaifenesin (Certuss-D) 1200 mg/Phenylephrine (Certuss-D) 25 mg oral tablets, extended release:
1 tablet orally every 12 hours not to exceed 2 doses daily.
Dextromethorphan (Certuss-D) 60 mg/Guaifenesin (Certuss-D) 600 mg/Phenylephrine (Certuss-D) 40 mg oral tablets, extended release:
1 tablet orally every 12 hours not to exceed 2 doses daily.
Dextromethorphan (Certuss-D) 60 mg/Guaifenesin (Certuss-D) 1000 mg/Phenylephrine (Certuss-D) 40 mg oral tablets, extended release:
1 tablet orally every 12 hours not to exceed 2 doses daily.
Dextromethorphan (Certuss-D) 20 mg/Guaifenesin (Certuss-D) 800 mg/Phenylephrine (Certuss-D) 20 mg oral tablets, extended release:
1 to 1.5 tablets orally every 12 hours not to exceed 3 tablets daily.
Dextromethorphan (Certuss-D) 30 mg/Guaifenesin (Certuss-D) 600 mg/Phenylephrine (Certuss-D) 20 mg oral tablets, extended release:
1 or 2 tablets orally twice a day not to exceed 2 doses daily.
Certuss-D 14 mg-288 mg-7 mg oral capsule:
1 capsule orally every 4 to 6 hours.
Dextromethorphan (Certuss-D) 15 mg/Guaifenesin (Certuss-D) 380 mg/Phenylephrine (Certuss-D) 10 mg oral capsule:
1 capsule orally every 4 hours not to exceed 6 tablets daily.
Dextromethorphan (Certuss-D) 20 mg/Guaifenesin (Certuss-D) 400 mg/Phenylephrine (Certuss-D) 10 mg oral tablet:
1 tablet orally every 4 to 6 hours not to exceed 4 tablets in 24 hours.
Dextromethorphan (Certuss-D) 20 mg/Guaifenesin (Certuss-D) 200 mg/Phenylephrine (Certuss-D) 10 mg/10 mL oral liquid:
1 prefilled spoon (10 mL) orally every 4 hours.
Dextromethorphan (Certuss-D) 5 mg/Guaifenesin (Certuss-D) 50 mg/Phenylephrine (Certuss-D) 2.5 mg/5 mL oral liquid:
20 mL orally every 4 hours. Do not take more than 6 doses in 24 hours.
Certuss-D 15 mg-350 mg-12 mg oral tablet:
1 tablet orally every 6 hours, not to exceed 4 tablets in 24 hours.
Certuss-D 10 mg-200 mg-5 mg/5 mL oral liquid:
10 mL orally every 4 hours. Do not take more than 6 doses in 24 hours.
Certuss-D 20 mg-400 mg-10 mg/5 mL oral liquid:
5 mL orally every 4 hours. Do not take more than 6 doses in 24 hours.
Certuss-D 5 mg-75 mg-2.5 mg/5 mL oral liquid:
20 mL orally every 4 hours. Do not take more than 6 doses in 24 hours.
Certuss-D 20 mg-400 mg-10 mg/20 mL oral liquid:
20 mL orally every 4 hours. Do not take more than 6 doses in 24 hours.
Usual Pediatric Dose for Cough and Nasal Congestion:
Dextromethorphan (Certuss-D) 5 mg/Guaifenesin (Certuss-D) 50 mg/Phenylephrine (Certuss-D) 2.5 mg/5 mL oral liquid:
over 6 months to less than 9 months: 0.75 mL orally 4 times daily.
over 9 months to 18 months: 1 mL orally 4 times daily.
Dextromethorphan (Certuss-D) 15 mg/Guaifenesin (Certuss-D) 100 mg/Phenylephrine (Certuss-D) 5 mg/5 mL:
over 2 yrs to less than 6 yrs: 2.5 mL orally every 6 hours not to exceed 10 mL daily.
over 6 yrs to less than 12 yrs: 5 mL orally every 6 hours not to exceed 20 mL daily.
over 12 yrs: 10 mL orally every 6 hours not to exceed 40 mL daily.
Dextromethorphan (Certuss-D) 15 mg/Guaifenesin (Certuss-D) 300 mg/Phenylephrine (Certuss-D) 10 mg/5 mL:
over 6 yrs to less than 12 yrs: 5 mL orally every 6 hours not to exceed 20 mL daily.
over 12 yrs: 10 mL orally every 6 hours not to exceed 40 mL daily.
Dextromethorphan (Certuss-D) 20 mg/Guaifenesin (Certuss-D) 100 mg/Phenylephrine (Certuss-D) 10 mg/5 mL:
over 2 yrs to less than 6 yrs: 1.25 mL orally every 4 to 6 hours not to exceed 7.5 mL daily.
over 6 yrs to less than 12 yrs: 2.5 mL orally every 4 to 6 hours not to exceed 15 mL daily.
over 12 yrs: 5 mL orally every 4 to 6 hours not to exceed 30 mL daily.
Dextromethorphan (Certuss-D) 20 mg/Guaifenesin (Certuss-D) 200 mg/Phenylephrine (Certuss-D) 5 mg/5 mL:
over 2 yrs to less than 6 yrs: 2.5 mL orally every 8 hours not to exceed 7.5 mL daily.
over 6 yrs to less than 12 yrs: 5 mL orally every 8 hours not to exceed 15 mL daily.
over 12 yrs: 10 mL orally every 8 hours not to exceed 30 mL daily.
Dextromethorphan (Certuss-D) 25 mg/Guaifenesin (Certuss-D) 175 mg/Phenylephrine (Certuss-D) 12.5 mg/5 mL oral syrup:
over 2 yrs to less than 6 yrs: 1.25 mL orally four times daily.
over 6 yrs to less than 12 yrs: 2.5 mL orally four times daily.
over 12 yrs: 5 mL orally four times daily.
Dextromethorphan (Certuss-D) 23 mg/Guaifenesin (Certuss-D) 600 mg/Phenylephrine (Certuss-D) 9 mg oral tablets, extended release:
over 6 yrs to less than 12 yrs: one half tablet orally every 12 hours not to exceed 1 tablet daily
over 12 yrs: 1 or 2 tablets orally every 12 hours not to exceed 4 tablets daily.
Dextromethorphan (Certuss-D) 20 mg/Guaifenesin (Certuss-D) 800 mg/Phenylephrine (Certuss-D) 20 mg oral tablets, extended release:
over 6 yrs to less than 12 yrs: 1/2 tablet orally every 12 hours not to exceed 1 tablet daily.
over 12 yrs: 1 to 1.5 tablets orally every 12 hours not to exceed 3 tablets daily.
Dextromethorphan (Certuss-D) 25 mg/Guaifenesin (Certuss-D) 550 mg/Phenylephrine (Certuss-D) 20 mg oral tablets, extended release:
over 6 yrs to less than 12 yrs: 1/2 tablet orally every 12 hours not to exceed 1 tablet daily.
over 12 yrs: 1 to 2 tablets orally every 12 hours not to exceed 3 tablets daily.
Dextromethorphan (Certuss-D) 25 mg/Guaifenesin (Certuss-D) 600 mg/Phenylephrine (Certuss-D) 20 mg oral tablets, extended release:
over 2 yrs to less than 6 yrs: 1/2 tablet orally every 12 hours not to exceed 1 tablet daily.
over 6 yrs to less than 12 yrs: 1/2 to 1 tablet orally every 12 hours not to exceed 1 1/2 tablet daily.
over 12 yrs: 1 to 2 tablets orally every 12 hours not to exceed 3 tablets daily.
Dextromethorphan (Certuss-D) 30 mg/Guaifenesin (Certuss-D) 1200 mg/Phenylephrine (Certuss-D) 30 mg oral tablets, extended release:
over 6 yrs to less than 12 yrs: 1/2 tablet orally every 12 hours not to exceed 1 tablet daily.
over 12 yrs: 1 tablet orally every 12 hours not to exceed 2 tablets daily.
Dextromethorphan (Certuss-D) 30 mg/Guaifenesin (Certuss-D) 600 mg/Phenylephrine (Certuss-D) 10 mg oral tablets, extended release:
over 6 yrs to less than 12 yrs: 1 tablet orally every 12 hours not to exceed 2 tablets daily.
over 12 yrs: 1 to 2 tablets orally every 12 hours not to exceed 4 tablets daily.
Dextromethorphan (Certuss-D) 30 mg/Guaifenesin (Certuss-D) 1000 mg/Phenylephrine (Certuss-D) 20 mg oral tablets, extended release:
over 6 yrs to less than 12 yrs: 1/2 tablet orally every 12 hours not to exceed 1 tablet daily.
over 12 yrs: 1 tablet orally every 12 hours not to exceed 2 tablets daily.
Dextromethorphan (Certuss-D) 40 mg/Guaifenesin (Certuss-D) 200 mg/Phenylephrine (Certuss-D) 20 mg/10 mL:
over 3 yrs to less than 6 yrs: 2.5 mL orally every 12 hours not to exceed 5 mL daily.
over 6 yrs to less than 12 yrs: 5 mL orally every 12 hours not to exceed 10 mL daily.
over 12 yrs: 10 mL orally every 12 hours not to exceed 20 mL daily.
Dextromethorphan (Certuss-D) 45 mg/Guaifenesin (Certuss-D) 1200 mg/Phenylephrine (Certuss-D) 25 mg oral tablets, extended release:
over 6 yrs to less than 12 yrs: 1/2 tablet orally every 12 hours not to exceed 2 doses daily.
over 12 yrs: 1 tablet orally every 12 hours not to exceed 2 doses daily.
Dextromethorphan (Certuss-D) 60 mg/Guaifenesin (Certuss-D) 600 mg/Phenylephrine (Certuss-D) 40 mg oral tablets, extended release:
over 6 yrs to less than 12 yrs: 1/2 tablet orally every 12 hours not to exceed 2 doses daily.
over 12 yrs: 1 tablet orally every 12 hours not to exceed 2 doses daily.
Dextromethorphan (Certuss-D) 60 mg/Guaifenesin (Certuss-D) 1000 mg/Phenylephrine (Certuss-D) 40 mg oral tablets, extended release:
over 6 yrs to less than 12 yrs: 1/2 tablet orally every 12 hours not to exceed 2 doses daily.
over 12 yrs: 1 tablet orally every 12 hours not to exceed 2 doses daily.
Dextromethorphan (Certuss-D) 5 mg/Guaifenesin (Certuss-D) 100 mg/Phenylephrine (Certuss-D) 2.5 mg/5 mL:
over 2 yrs to less than 6 yrs and 11 kg to 21 kg: 2.5 mL orally every 4 hours not to exceed 15 mL daily.
Dextromethorphan (Certuss-D) 30 mg/Guaifenesin (Certuss-D) 900 mg/Phenylephrine (Certuss-D) 30 mg oral tablets, extended release:
6 years to 12 years: 1/2 tablet orally every 12 hours not to exceed 1 tablet daily.
12 years or older: 1 tablet orally every 12 hours not to exceed 2 tablets daily.
Dextromethorphan (Certuss-D) 30 mg/Guaifenesin (Certuss-D) 600 mg/Phenylephrine (Certuss-D) 20 mg oral tablets, extended release:
12 years or older: 1 or 2 tablets orally twice a day not to exceed 2 doses daily.
Certuss-D 14 mg-288 mg-7 mg oral capsule:
over 12 yrs: 1 capsule orally every 4 to 6 hours.
Dextromethorphan (Certuss-D) 15 mg/Guaifenesin (Certuss-D) 380 mg/Phenylephrine (Certuss-D) 10 mg oral capsule:
12 years or older: 1 capsule orally every 4 hours not to exceed 6 tablets daily.
Dextromethorphan (Certuss-D) 20 mg/Guaifenesin (Certuss-D) 400 mg/Phenylephrine (Certuss-D) 10 mg oral tablet:
6 years to 12 years: 1/2 tablet orally every 4 to 6 hours not to exceed 2 tablets in 24 hours.
over 12 yrs 1 tablet orally every 4 to 6 hours not to exceed 4 tablets in 24 hours.
Dextromethorphan (Certuss-D) 20 mg/Guaifenesin (Certuss-D) 200 mg/Phenylephrine (Certuss-D) 10 mg/10 mL oral liquid:
12 years or older: 1 prefilled spoon (10 mL) orally every 4 hours.
Dextromethorphan (Certuss-D) 5 mg/Guaifenesin (Certuss-D) 50 mg/Phenylephrine (Certuss-D) 2.5 mg/5 mL oral liquid:
4 years to 5 years: 5 mL orally every 4 hours not to exceed 6 doses in 24 hours.
6 years to 11 years: 10 mL orally every 4 hours not to exceed 6 doses in 24 hours.
12 years or older: 20 mL orally every 4 hours not to exceed 6 doses in 24 hours.
Certuss-D 15 mg-350 mg-12 mg oral tablet:
12 years or older: 1 tablet orally every 6 hours, not to exceed 4 tablets in 24 hours.
Certuss-D 10 mg-200 mg-5 mg/5 mL oral liquid:
12 years or older: 10 mL orally every 4 hours. Do not take more than 6 doses in 24 hours.
Certuss-D 5 mg-100 mg-2.5 mg/5 mL oral liquid:
4 years to 5 years: 5 mL orally every 4 hours not to exceed 6 doses in 24 hours.
6 years to 11 years: 10 mL orally every 4 hours not to exceed 6 doses in 24 hours.
Certuss-D 20 mg-400 mg-10 mg/5 mL oral liquid:
12 years or older: 5 mL orally every 4 hours. Do not take more than 6 doses in 24 hours.
Certuss-D 5 mg-75 mg-2.5 mg/5 mL oral liquid:
2 years to 5 years: 5 mL orally every 4 hours. Do not take more than 6 doses in 24 hours.
6 years to 11 years: 10 mL orally every 4 hours. Do not take more than 6 doses in 24 hours.
12 years or older: 20 mL orally every 4 hours. Do not take more than 6 doses in 24 hours.
Certuss-D 20 mg-400 mg-10 mg/20 mL oral liquid:
12 years or older: 20 mL orally every 4 hours. Do not take more than 6 doses in 24 hours.
Dextromethorphan (Certuss-D) 28 mg/Guaifenesin (Certuss-D) 388 mg/Phenylephrine (Certuss-D) 10 mg oral tablets:
Over 12 years of age: 1 tablet orally every 4 hours not to exceed 6 tablets in 24 hours
6 years to under 12 years of age: 1/2 tablet orally every 4 hours not to exceed 3 tablets in 24 hours
Dextromethorphan (Certuss-D) 28 mg/Guaifenesin (Certuss-D) 388 mg/Phenylephrine (Certuss-D) 10 mg /5 mL oral liquid:
12 years and over: 5 mL orally every 6 to 8 hours not to exceed 4 doses 24 hours
6 years to under 12 years of age: 2.5 mL orally every 6 to 8 hours not to exceed 4 doses 24 hours
2 years to 6 years of age: 1.25 mL orally every 6 to 8 hours not to exceed 4 doses 24 hours
Dextromethorphan (Certuss-D) 7.5 mg/Guaifenesin (Certuss-D) 88 mg/Phenylephrine (Certuss-D) 2.5 mg /1 mL oral liquid:
6 years to under 12 years of age: 2 mL orally every 6 to 8 hours not to exceed 4 doses 24 hours
2 years to 6 years of age: 1 mL orally every 6 to 8 hours not to exceed 4 doses 24 hours
See also:
What is the most important information I should know about Certuss-D?
Hyperthyroidism; HTN & coronary disease. Concurrent use or use w/in 2 wk of MAOI therapy. Childn <2 yr.
Use Certuss-D controlled-release and sustained-release tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Certuss-D controlled-release and sustained-release tablets by mouth with or without food.
- Drink plenty of water while taking Certuss-D controlled-release and sustained-release tablets.
- Swallow Certuss-D controlled-release and sustained-release tablets whole. Do not break, crush, or chew before swallowing. Some brands of Certuss-D controlled-release and sustained-release tablets may be broken in half before taking. If you have difficulty swallowing the whole tablet, ask your pharmacist if your brand of medicine may be broken in half.
- If you miss a dose of Certuss-D controlled-release and sustained-release tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Certuss-D controlled-release and sustained-release tablets.
See also:
What other drugs will affect Certuss-D?
If you are taking this medication under your doctor's direction, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.
Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking isocarboxazid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, or tranylcypromine during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially: beta blockers (e.g., metoprolol, atenolol), guanethidine, certain inhaled anesthetics (e.g., halothane), methyldopa, reserpine, tricyclic antidepressants (e.g., amitriptyline, desipramine).
Guaifenesin (Certuss-D) is available in both prescription and nonprescription products. Check the labels on all your medications carefully to make sure you are not taking more than one Guaifenesin (Certuss-D)-containing product.
Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about the safe use of those products.
This medication may interfere with certain medical/laboratory tests (including urine 5-HIAA/VMA levels, brain scan for Parkinson's disease), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
See also:
What are the possible side effects of Certuss-D?
Dizziness, headache, nausea, nervousness, or trouble sleeping may occur. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.
If your doctor has prescribed this drug, remember that your doctor has prescribed it because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor if any of these unlikely but serious side effects occur: mental/mood changes (e.g., confusion, hallucinations), shaking (tremors), weakness.
Tell your doctor if any of these rare but very serious side effects occur: fast/slow/irregular heartbeat.
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.