Cardiprin 100

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Cardiprin 100

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Medically reviewed

Rosario Oropesa

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Cardiprin 100

Property Description
Active ingredient Acetylsalicylic Acid, Glycine
Form Soluble Tablet (Dispersible Formulation)
Pharmacological class Platelet Aggregation Inhibitor
Common use Cardiovascular prophylaxis / Antithrombotic
Origin Synthetic Compound (Acetylsalicylic Acid)

What Type of Medicine is Cardiprin 100? (Identity and Classification)

Cardiprin 100 is classified as an Antithrombotic Drug, specifically belonging to the Platelet Aggregation Inhibitor class, and serves as a dedicated Cardio-Protective Agent. This Fixed-Dose Combination Drug is intended as a prophylactic medication for the long-term management of cardiovascular risk in adults. Its primary purpose is to aid in the prevention of cardiovascular events related to the formation of blood clots. Research confirms that this class of drug is crucial for preventing serious health outcomes in high-risk patients. The widely recognized benefit of this medicine is its established ability to reduce the stickiness of blood platelets, which helps to maintain consistent blood flow.

Cardiprin 100 Composition: Acetylsalicylic Acid and Glycine

The formulation contains two Active ingredients / Chemical substances: Acetylsalicylic Acid (ASA) and the amino acid Glycine. The ASA component is a well-established Synthetic Compound within the Salicylic Acid Derivative chemical group. The product is a Soluble Tablet—a specialized Dispersible Formulation for Oral use after mixing with water. While ASA provides the essential antiplatelet function, the inclusion of Glycine is a unique characteristic of this specific preparation, aiding in rapid dissolution and enhancing patient tolerance. Pharmacological studies support that incorporating a dispersing agent like Glycine into the formulation is beneficial for patient adherence, making the medication easier to integrate into a long-term preventative routine.

How is Cardiprin 100 Distinct from Standard Aspirin? (Targeted Action Overview)

The distinction lies in the drug's highly specific mechanism and Low-Dose Regimen, which focuses its action on a precise Physiological action—the Irreversible Cyclooxygenase-1 (COX-1) inhibition in platelets. This targeted approach minimizes general systemic effects, ensuring that the medication's purpose remains anchored in its role as an Antithrombotic Drug for sustained, preventative cardiovascular health support. This targeted action is clinically recognized as the gold standard for reducing the likelihood of clot formation in the at-risk population. The unique Soluble Tablet form further differentiates it from generic enteric-coated or standard tablet forms of Low-Dose Aspirin.

What side effects are possible with Cardiprin 100?

Possible side effects and safety information

The safety profile of Cardiprin 100, which contains low-dose Acetylsalicylic Acid (ASA), is primarily structured around its antiplatelet effect and potential for gastrointestinal irritation, as documented in government regulatory sources. Adverse reactions are formally classified by frequency and system-organ class.


Frequency-Classified Adverse Reactions

The most commonly listed adverse reactions include dyspepsia, nausea, vomiting, and mild gastrointestinal bleeding (occult blood loss), which are classified as common (affecting 1 in 100 to less than 1 in 10 users). Less frequent reactions, classified as uncommon (e.g., urticaria, rash, rhinitis) or rare (e.g., severe hypersensitivity), are also documented in official labeling.


System-Organ Classes and Serious Concerns

Adverse effects are formally grouped in regulatory documents, involving primarily the Blood and Lymphatic System Disorders (due to increased bleeding tendency) and Gastrointestinal Disorders (including oesophagitis and ulcers). Rare but severe adverse reactions are listed, such as major haemorrhage (cerebral or severe gastrointestinal) and, of particular note, the risk of Reye's syndrome in children and adolescents with viral infections.


Population-Specific Safety and Restrictions

Official labeling includes specific safety considerations. ASA is contraindicated in children and adolescents for viral infections due to the established risk of Reye's syndrome. Safety constraints also apply to individuals with severe hepatic impairment or severe renal failure. The risk of iron deficiency anemia is noted as a pattern associated with long-term exposure due to chronic occult blood loss. Absolute contraindications for use include active peptic ulcer disease and current gastrointestinal bleeding.

Overdose and Emergency Response

Officially documented overdose of Acetylsalicylic Acid (ASA), the active component of Cardiprin 100, may initially present with Tinnitus (ringing in the ears), Nausea, Vomiting, Hyperventilation (rapid breathing), Sweating, and Headache.

Documented Severe Outcomes

Severe toxicity involves critical Metabolic Acidosis, Respiratory Failure, and Cardiovascular Collapse. CNS effects, including Seizures, Coma, and Altered Mental Status, are officially listed as life-threatening outcomes.

When to Seek Immediate Medical Help

For any suspected overdose, regulatory guidance mandates that patients seek immediate medical attention and that Hospital admission is required for symptomatic cases.

Management and Monitoring

Management is supportive; no specific antidote is known. Documented procedural measures include the potential use of Activated Charcoal and intensive treatment such as Urinary Alkalinization or Haemodialysis for severe cases. Close monitoring of Serum Salicylate concentration and Acid-Base Status is essential.

Population-Specific Considerations

Regulatory labeling notes specific considerations: The elderly (age >70 years) face an increased risk of severe toxicity. Young children (age ≤4 years) may uniquely present with an earlier, dominant Metabolic Acidosis.

Therapeutic Uses of Cardiprin 100

What Cardiprin 100 Treats: Main Uses and Benefits

This medication is applied across therapeutic domains where additional symptomatic support is needed for cardiovascular and cerebrovascular health. Cardiprin 100 is relevant in clinical settings marked by the potential for recurrent, acute events. It is generally used for conditions involving episodic or fluctuating manifestations, used for conditions that may present with disruptive symptom manifestations related to systemic imbalance.

The use of this medicine is common when symptoms intensify and supportive relief is needed, especially during phases where patients experience heightened discomfort or physiological strain. It helps address symptom clusters that interfere with daily comfort. Its use provides support that generally helps ease the overall symptom burden.

“It provides supportive relief when symptoms interfere with routine activities, contributing to easing the overall symptom load.”

Quick Fact: Assistance with Physiological Strain

Regulatory References

  1. Australian Therapeutic Goods Administration (TGA) Monograph

Eligibility and Restrictions for Use

Populations for Whom Use is Contraindicated

Cardiprin 100 is strictly contraindicated and must not be used by several groups, as defined by official regulatory labeling. This includes individuals with a known hypersensitivity (allergy) to aspirin or other NSAIDs. The medicine is prohibited for patients who have an active peptic ulcer, an episode of significant bleeding, or a diagnosed bleeding disorder. Individuals with severe hepatic impairment or severe renal impairment are also ineligible. Use is forbidden during the third trimester of pregnancy. The medicine is contraindicated in children and adolescents with fever or viral symptoms due to the risk of Reye's syndrome.


Eligibility and Restricted Use

Cardiprin 100 is intended for adults requiring long-term cardiovascular prophylaxis. Use is restricted and requires medical supervision for patients with mild to moderate hepatic or renal impairment, a history of gout, or asthma. Use during the first and second trimesters of pregnancy is generally restricted, and the medicine is not recommended for breastfeeding women.

What should I know about interactions with other medicines?

Cardiprin 100 Interactions with other medicines and products

Official regulatory information for acetylsalicylic acid (ASA), the active ingredient in Cardiprin 100, documents interactions primarily related to pharmacodynamic effects and altered drug concentrations.

Interaction Classifications

Classification Interacting Medicines/Categories
Formal Contraindication Ketorolac (NSAID)
Increased Bleeding Risk Anticoagulants (e.g., Warfarin, Apixaban), other Antiplatelet Agents (e.g., Clopidogrel), NSAIDs, SSRIs, Corticosteroids
Altered Drug Levels Methotrexate (increased serum levels), Phenytoin (protein displacement), Valproic Acid (increased serum levels)

Timing and Population Notes

The co-administration of Ibuprofen with immediate-release ASA requires a specific timing separation to avoid interference with the antiplatelet effect. Official guidance suggests taking Ibuprofen at least 8 hours before or at least 30 minutes after the ASA dose.

Interactions involving ASA may be more pronounced in certain populations, and the use of the medicine is advised to be avoided in patients with severe renal failure or severe hepatic insufficiency.

Other Documented Interactions

Co-use with heavy or chronic alcohol consumption (defined as three or more drinks daily) is noted to increase the chance of gastrointestinal bleeding. Certain herbal supplements (such as Garlic and Ginger) are also officially documented to potentially change the effect of ASA.

Mechanism of Action

How Cardiprin 100 Works


The core mechanism involves the Acetylsalicylic Acid ( ASA) component permanently shutting down the Cyclooxygenase-1 ( COX-1) enzyme in circulating platelets through covalent acetylation. This irreversible inhibition immediately halts the platelet's ability to produce Thromboxane A2 ( TXA2), the key signaling mediator that amplifies platelet aggregation and promotes platelet adhesion.

The anti-aggregatory effect is sustained because the platelet is an anuclear cell; once its COX-1 enzyme is permanently inhibited, the cell cannot synthesize new enzyme. Consequently, the effect persists for the entire lifespan of the affected platelet, typically 8 to 10 days, until new platelets are released into circulation. This mechanism results in a continuous, predictable reduction in the blood's capacity to form occlusive platelet masses.

The dispersible formulation, aided by Glycine, ensures the rapid dissolution and efficient absorption of the ASA parent drug. This rapid uptake is crucial because it maximizes the exposure of circulating platelets to the ASA molecule before it is metabolized. This facilitates the chemical interaction necessary for effective and immediate COX-1 acetylation, leading to a rapid initiation of platelet inhibition.

Dosage and Administration Information

Administration Guidelines for Cardiprin 100

The administration of Cardiprin 100 (Acetylsalicylic Acid 100 mg dispersible tablet) follows specific guidelines for long-term antiplatelet prophylaxis. The use of this medicine requires initiation and ongoing management by a medical professional.

Instruction Detail
Route of Administration Oral use.
Dosing Schedule The standard maintenance dose is 100 mg once daily. In acute clinical situations requiring a rapid effect, an initial loading dose of up to 300 mg may be administered.
Timing The daily dose should be taken at a consistent time each day and is preferably administered at least 30 minutes before meals.
Preparation The dispersible tablet may be placed on the tongue to dissolve instantly without water, or it may be swallowed whole with water.
Age-Specific Rules The use of this medicine is generally restricted and not recommended for individuals under 16 years of age.
Missed Dose If a dose is missed, it should be skipped if the time for the next scheduled dose is near; a double dose must not be taken to compensate.

Procedural Structure

The use protocol is structured around consistent daily intake, starting with the prescribed 100 mg dose. The administration method is flexible, permitting the tablet to be dispersed on the tongue or swallowed whole. This regimen is intended for long-term daily use and includes constraints such as the requirement for physician oversight and restrictions for patients with severe hepatic or renal failure. This established procedural framework ensures a standardized administration model.

Recent Clinical Evidence

Recent Clinical Evidence

Efficacy in Secondary Prevention

Studies focused on Cardiprin 100 (low-dose aspirin, 100 mg) primarily evaluate its role in the secondary prevention of cardiovascular events. This involves individuals who have previously experienced a myocardial infarction (heart attack) or stroke.

  • Primary Findings: Large-scale trials and meta-analyses suggest that the long-term, daily administration of low-dose aspirin is associated with a reduction in the risk of major adverse cardiovascular events (MACE) in at-risk populations. The key mechanism studied relates to the irreversible inhibition of platelet aggregation.
  • Clinical Endpoints: Research typically tracks the occurrence of non-fatal stroke, non-fatal myocardial infarction, and vascular death as primary endpoints.

Safety Profile and Risk Management

Research has consistently evaluated the balance of benefit and risk associated with long-term low-dose aspirin therapy. The main safety consideration studied is the potential for increased risk of serious bleeding events.

Research Focus Key Safety Finding
Gastrointestinal Bleeding Studies report a measurable, dose-dependent increase in upper gastrointestinal bleeding events compared to placebo.
Intracranial Hemorrhage Research explores the small, absolute increase in the risk of hemorrhagic stroke.

Trial protocols emphasize that the net benefit of low-dose aspirin for secondary prevention generally outweighs the bleeding risk in patients with a history of cardiovascular events. Eligibility is determined based on individual patient risk factors and prior health history, a process that requires clinical judgment.

Key Studies & References Aspirin for the primary prevention of cardiovascular events: a systematic review and meta-analysis of randomized controlled trials

Frequently Asked Questions (FAQ)

Common questions about Cardiprin 100 (FAQ)

Q: How quickly is Cardiprin 100 expected to start working?

A: The dispersible formulation is described in official documents as ensuring rapid dissolution and efficient absorption of the active ingredient. This design is intended to facilitate a rapid initiation of anti-platelet action within the body.


Q: If I stop taking Cardiprin 100, how long does the effect last?

A: The active ingredient permanently inhibits the function of the affected platelets. This effect is sustained until new platelets are released into circulation, a process that official product information states takes approximately 8 to 10 days.


Q: Can Cardiprin 100 be used by children?

A: Official guidelines state that the medicine is generally restricted and not recommended for individuals under 16 years of age. Furthermore, it is contraindicated (prohibited) for use in children and adolescents with viral infections due to the documented risk of Reye's syndrome.


Q: What does official guidance say about taking Cardiprin 100 with food?

A: Official administration guidance states that the daily dose is preferably administered at least 30 minutes before meals. The timing is noted as a preference in official documents.


Q: Do people take Cardiprin 100 for pain relief?

A: The official purpose of Cardiprin 100 is strictly defined as a cardio-protective, prophylactic medication for the long-term management of cardiovascular risk. While the active ingredient, acetylsalicylic acid, is used for pain relief in higher doses, this low-dose formulation is intended specifically for its anti-thrombotic (anti-clotting) purpose.


Q: Is it normal to experience dizziness when starting Cardiprin 100?

A: Commonly listed adverse reactions in official labeling include mild gastrointestinal issues like nausea, vomiting, and upset stomach. However, symptoms such as confusion or severe dizziness are noted in some official sources as symptoms that warrant professional review.


Q: Are there any long-term side effects associated with Cardiprin 100 use?

A: Studies on long-term use consistently focus on the balance of benefit and risk. The main safety consideration noted is the potential for an increased risk of serious bleeding events. Risks associated with chronic, long-term exposure also include iron deficiency anemia due to ongoing, mild occult blood loss.


Q: Are there specific symptoms that require stopping Cardiprin 100 and seeking help?

A: Rare but severe adverse reactions are listed in regulatory documents, such as major haemorrhage or severe hypersensitivity reactions. These are noted as concerns that official information states warrant immediate professional review.


Q: Is there a list of major drug classes that interact with Cardiprin 100?

A: Official regulatory documents classify documented interactions into groups based on their effect. These include increased bleeding risk with Anticoagulants, other Antiplatelet Agents, NSAIDs, SSRIs, and Corticosteroids.


Q: Is Cardiprin 100 appropriate for people with kidney issues?

A: Official patient information states that the medicine is strictly contraindicated (forbidden) for individuals with severe renal (kidney) impairment. Use is also restricted for patients with mild to moderate renal impairment.


Q: Is there specific information about Cardiprin 100 and pregnancy or breastfeeding?

A: Use is strictly forbidden during the third trimester of pregnancy. Official guidance states that use during the first and second trimesters is generally restricted. The medicine is also not generally recommended for use by women who are breastfeeding.


Q: Is Cardiprin 100 coated or buffered?

A: The medicine is officially described in regulatory documents as a soluble, dispersible tablet formulation. The official labeling does not use the terms 'enteric-coated' or 'buffered' to describe the features of this specific preparation.


Q: Do studies support the use of Cardiprin 100 for heart health?

A: Research evidence primarily focuses on the use of low-dose aspirin in the secondary prevention of major adverse cardiovascular events (MACE). Studies suggest that long-term, daily use is associated with a reduction in the risk of MACE in individuals who are already at risk.


Q: What kind of research has been done on Cardiprin 100?

A: Clinical research focuses on the long-term, daily administration of low-dose aspirin in at-risk individuals. The studies examine its efficacy in reducing major adverse cardiovascular events and consistently evaluate the balance of benefit against the risk of bleeding events.


Q: Are there any dietary restrictions when taking Cardiprin 100?

A: Official documentation notes that co-use with heavy or chronic alcohol consumption (defined as three or more drinks daily) may increase the chance of gastrointestinal bleeding. Certain herbal supplements are also documented to potentially alter the effects of the active ingredient.


Q: Why does the label mention a risk of bleeding?

A: The risk is highlighted because the core anti-platelet mechanism of the medicine continuously reduces the stickiness of blood platelets. This action, while preventing unwanted clot formation, also reduces the blood's capacity to form clots generally, which increases the tendency toward bleeding.


Q: Is Cardiprin 100 considered a preventative medicine?

A: Yes, official documents classify Cardiprin 100 as a prophylactic medication intended for the long-term management of cardiovascular risk. Its purpose is to aid in the prevention of cardiovascular events related to the formation of blood clots.


Q: Can you take other low-dose aspirin products at the same time as Cardiprin 100?

A: Official warnings in some regions advise, 'Do not substitute other medicines containing aspirin for this.' This suggests against the simultaneous use of separate, duplicative low-dose aspirin products.


Q: What should I know about Cardiprin 100 if I am scheduled for surgery?

A: If a person is scheduled for surgery, the surgeon or physician should be informed beforehand about the use of this medicine. Decisions on continuing or stopping the medicine before a procedure are determined by a healthcare professional based on individual risk factors.


Q: Does Cardiprin 100 contain lactose or gluten?

A: The official product composition details the active ingredients (Acetylsalicylic Acid and Glycine). While information on gluten is not specifically detailed, official labeling for similar dispersible aspirin products has been documented to list lactose as a non-active ingredient (excipient).


Q: Is it safe to drive or operate machinery while taking Cardiprin 100?

A: Regulatory information states that if specific side effects such as drowsiness, confusion, or severe dizziness are experienced, the ability to operate machinery may be affected.


Q: If a dose of Cardiprin 100 is missed, what is the general guidance?

A: Official patient information states that if a dose is missed, it should be skipped if the time for the next scheduled dose is near. It is explicitly noted that a double dose must not be taken to compensate for a missed one.


Q: Why are the tablets dispersible?

A: The dispersible formulation is a specific characteristic intended to ensure rapid dissolution and efficient absorption of the active ingredient. This manufacturing choice helps maximize the exposure of circulating platelets for effective anti-platelet action.


Q: Are there any known long-term benefits established by research?

A: Studies suggest that the long-term, daily administration of low-dose aspirin is associated with a reduction in the risk of major adverse cardiovascular events (MACE) in at-risk populations. This reduction in risk is considered the primary benefit theme of the long-term therapy.


Q: Is the absorption of Cardiprin 100 affected by antacids?

A: Official drug interaction information notes that antacids may potentially reduce the absorption of aspirin. This effect is a consideration, particularly when antacids are used chronically or in certain patient populations.


Q: Can Cardiprin 100 affect fertility?

A: Regulatory-related information does not provide clear evidence to suggest that taking aspirin will reduce fertility in either men or women. However, it is generally advised to seek advice if attempting to conceive.


Q: Does Cardiprin 100 expire?

A: Yes. Official disposal guidelines explicitly mention discarding 'Expired or unused' medicine according to local regulations, which indicates that the product has a defined shelf life.


Q: Can Cardiprin 100 be used if I have allergies to other medicines?

A: The medicine is strictly contraindicated (forbidden) for individuals with a known hypersensitivity or allergy to aspirin or to other Non-Steroidal Anti-inflammatory Drugs (NSAIDs).


Q: What are the official regulatory classifications for Cardiprin 100?

A: The medicine is officially classified as an Antithrombotic Drug, belonging to the Platelet Aggregation Inhibitor class. The active ingredient, Acetylsalicylic Acid, is further categorized as a Salicylic Acid Derivative.


Q: Is Cardiprin 100 available over-the-counter or only by prescription?

A: Official warnings consistently advise patients to 'consult a medical practitioner prior to commencing use.' This requirement for professional input is consistent with the status of medicines that require supervision, whether they are available over-the-counter under pharmacist control or fully by prescription.


Q: Do studies examine the use of Cardiprin 100 in people with diabetes?

A: Studies have examined the use of low-dose aspirin in adults with Type 2 diabetes. This research focuses on its potential role in lowering the risk of cardiovascular events in this population, who are often considered at elevated risk.


Q: What kind of evidence is available on Cardiprin 100's safety profile?

A: Research consistently evaluates the balance of benefit and risk associated with long-term therapy. The evidence focuses on tracking the frequency of bleeding events, including upper gastrointestinal bleeding, and the small, absolute increase in the risk of hemorrhagic stroke.


Q: Why is it necessary to take Cardiprin 100 regularly?

A: Consistent, long-term daily intake is required to maintain a continuous, predictable reduction in the blood's capacity to form clots. Because the inhibitory effect lasts only for the lifespan of the affected platelet, new daily dosing is required as new platelets are released.


Q: Is Cardiprin 100 manufactured in a specific way that affects how it works?

A: Yes. The specialized dispersible tablet formulation, which includes the amino acid Glycine, is supported by pharmacological studies. This aids in rapid dissolution and efficient absorption, facilitating the rapid anti-platelet action.


Q: Does Cardiprin 100 affect blood sugar levels?

A: Research has indicated that the active ingredient, acetylsalicylic acid, can stimulate the secretion of insulin and glucagon. Studies suggest it may also affect fasting serum glucose in both normal and diabetic subjects.


Q: Can I use Cardiprin 100 if I have a history of gout?

A: Official documents state that the use of this medicine is restricted in patients with a history of gout.

How should Cardiprin 100 be stored and disposed of?

Storage and Disposal Conditions

Official Storage Requirements

Cardiprin 100 must be stored at controlled room temperature, specifically between 15, C and 30, C (59, F and 86, F), as stated in regulatory labeling. The medicine must be kept in its original container and must remain tightly closed to protect the dispersible tablets from moisture and environmental degradation. The official documentation explicitly mandates not to freeze the product and to ensure it is kept out of the sight and reach of children.

Disposal of Unused Medicine

Expired or unused Cardiprin 100 should be disposed of according to local regulatory guidelines for pharmaceutical waste. The preferred method is using an authorized drug take-back program. If this is unavailable, the product may be discarded in the household trash after mixing it with an unappealing substance, such as coffee grounds or dirt, and sealing it in a plastic bag.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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