Breen

Cefpodoxime

Upper and lower respiratory tract infections: tonsillitis, pharyngitis, acute sinusitis, acute bronchitis, pneumonia, exacerbation of chronic pneumonia (especially in people who abuse alcohol, smokers and people over 65 years of age).

Dosage is individual. Inside, with meals 2 times a day (every 12 hours), the daily dose for adults and adolescents is on average 200-400 mg, in patients with severe renal impairment (creatinine Cl below 40 ml / min), the single dose is halved.

Hypersensitivity, age (up to 12 years).

Nausea, vomiting, abdominal pain, diarrhea, headache, thrombocytosis, thrombocytopenia, leukopenia, eosinophilia, transient increase in the level of hepatic transaminases, alkaline phosphatase, urea and creatinine in the blood, skin rashes, itching, and other allergic reactions.

Like other cephalosporins of the third generation, it acts on most Gram-positive and gram-negative microorganisms. Resistant to the action of beta-lactamases of microorganisms. It does not affect Streptococcus spp. of group D, Staphylococcus spp., resistant to methicillin, Corynebacterium of groups J and K, Pseudomonas aeruginosa, Listeria monocytogenes, Acinetobacter baumannii, Clostridium difficile, Bacteroides spp.

It penetrates well into the lung tissue, bronchial mucosa, pleural fluid, palatine tonsils, interstitial fluid. It is displayed mainly in an unchanged form.

• Cephalosporins