Bioxtra

this medicine is a saliva substitute for patients with dryness of the oral mucosa and throat e.g. maintenance of oral hygiene in intensive care units, patients receiving radiotherapy treatment, following oral surgery, during treatments with certain drugs which suppress saliva production such as some antidepressants and chemotherapy agents.

this medicine is prescribable on FP10/GP10 for patients suffering from a dry mouth as a result of radiotherapy or sicca syndrome (xerostomia)

All prescriptions must be endorsed ACBS ( Advisory Committee on Borderline Substances)

Bioxtra are manmade forms of the mucus secretions normally produced in the human mouth. Bioxtra help to create artificial saliva when the body does not produce enough on its own.

Bioxtra are used to help relieve dryness and pain or discomfort in the mouth or throat that may be caused by certain disease conditions, medications, surgery, or chemotherapy and radiation treatments.

Bioxtra may also be used for purposes not listed in this medication guide.

Usual Adult Dose for Mucositis:

Caphosol, NeutraSal:

For use during high dose chemotherapy or radiation treatment: 4 doses per day orally from the onset of the cancer treatment. Up to 10 doses per day orally if pain from mucositis is experienced. Use for the duration of the treatment or as instructed by physician.

Directions for use:

(1) Mix as directed.

(2) Swish the mouth thoroughly for 1 min with 1/2 of the solution and spit out.

(3) Repeat with the remaining 1/2 of the solution and spit out. Use immediately after mixing the solution.

Usual Adult Dose for Xerostomia:

Bioxtra: Use 2 sprays 3 to 4 times per day or as directed.

Caphosol, Neutrasal: Use 2 to 10 times per day or as instructed by physician.

Directions for use:

(1) Mix as directed.

(2) Swish the mouth thoroughly for 1 min with 1/2 of the solution and spit out.

(3) Repeat with the remaining 1/2 of the solution and spit out. Use immediately after mixing the solution.

Bioxtra Lozenge: Let one Bioxtra Lozenge dissolve slowly in the mouth when needed. To obtain optimal effect, move the lozenge around in the mouth. Repeat as necessary. Do not exceed 16 lozenges in 24 hours.

Bioxtra Liquid: Shake bottle well. Take 2 ml (or about 1/2 teaspoon) of Bioxtra Liquid and rinse around in the mouth before swallowing. Use as needed.

Oasis Moisturizing Mouthwash: Rinse for 30 seconds with one ounce of mouthwash first thing in the morning and before going to bed or as needed. Do not swallow.

Oasis Moisturizing Mouth Spray: Spray 1 to 2 times into the affected areas of mouth. Use as required up to a maximum of 30 times or 60 sprays a day.

Orajel Dry Mouth Moisturizing Gel: Apply a one inch strip of product directly to tongue and around the inside and outside of the tooth and gum surface. Do not rinse out. Use as needed or as directed by a dentist or doctor.

Usual Pediatric Dose for Xerostomia:

Oasis Moisturizing Mouth Spray: For children 2 years of age and older. Spray 1 to 2 times into the affected areas of mouth. Use as required up to a maximum of 30 times or 60 sprays a day.

Orajel Dry Mouth Moisturizing Gel: For children 2 years of age and older. Apply a one inch strip of product directly to tongue and around the inside and outside of the tooth and gum surface. Do not rinse out. Use as needed or as directed by a dentist or doctor.

See also:
What is the most important information I should know about Bioxtra?

contraindicated in patients with fructose

intolerance or a known history of hypersensitivity to any of the ingredients.

A saliva substitute is for use only in the mouth. Do not get it in your eyes.

Use your saliva substitute product exactly as directed on the label, or as prescribed by your doctor.

Bioxtra work inside your mouth and are not meant to be swallowed.

To use the oral rinse or other liquid Bioxtra, swish a small amount in your mouth for 30 seconds, then spit out.

The oral powder must be mixed with about 1 ounce of water before using it. Stir the mixture and use it right away, even if you need to swish 2 or 3 times to get the full amount. Do not save the mixture for later use.

Shake the oral spray gently before each use and spray directly into your mouth and onto your tongue.

The tablet or lozenge can be held in the mouth for long periods of time, even while you are sleeping. Some tablets are pressed onto to your tooth or gums to help hold them in place.

Saliva substitute gel, paste, or swabs may be applied directly onto the gums, tongue, teeth, or sides of the mouth. Follow all instructions carefully.

How often you use a saliva substitute may depend on your condition or your medication schedule.

In most cases, Bioxtra are used 3 to 5 times per day or whenever your mouth feels dry and uncomfortable. When used during chemotherapy or radiation, you may need to use Bioxtra up to 10 times per day beginning on or before the day of your treatment. Follow all dosing instructions very carefully.

Do not allow a child to use this medicine without adult supervision.

Bioxtra may be only part of a complete treatment program that includes using other oral hygiene methods. Follow your doctor's instructions very closely.

Store your saliva substitute as directed on the product label. Avoid moisture, heat, and light.

See also:
What other drugs will affect Bioxtra?

There are no known interactions between this product and any

medicinal or other products.

See also:
What are the possible side effects of Bioxtra?

Applies to Bioxtra: powder, solution, spray

When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur while taking Bioxtra (the active ingredient contained in Bioxtra)

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).