Components:
Method of action:
Medically reviewed by Oliinyk Elizabeth Ivanovna, PharmD. Last updated on 03.04.2022
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Top 20 medicines with the same components:
Bigunal
Buformin
Acetonuric diabetes in overweight, insulin-dependent type II diabetes mellitus, uncorrected by diet.
Inside, during meals, starting from 50-100 mg/day, followed by an increase in the dose (but not more than 300 mg).
Hypersensitivity, insulin-dependent diabetes mellitus, ketonuria, hyperglycemic coma, pregnancy, lactation.
Dyspeptic disorders (loss of appetite, metallic taste in the mouth, nausea, vomiting, diarrhea), weakness, weight loss.
It is manifested by lactate acidosis.
It is rapidly absorbed in the intestine. Absorption-about 80%. Cmax in plasma-after 2.5 hours. It is excreted by the kidneys. T1/2 - 3-4 hours —
- Hypoglycemic synthetic and other drugs
The hypoglycemic effect is weakened by phenothiazine derivatives (aminazine), corticosteroids, thyroid — stimulating hormones, estrogens, diuretics, and enhanced by MAO inhibitors, antidiabetic sulfonamides, and salicylates.