Components:
Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 24.03.2022
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- Non-hormonal contraceptives
G02BB Intravaginal contraceptives
Benzalkonium chloride
Benzalkonium
Local contraception for women of reproductive age (the presence of contraindications to the use of oral contraceptives or intrauterine contraception, the postpartum period, the lactation period, the period after termination of pregnancy, the premenopausal period, the need for episodic protection from pregnancy, the omission or delay in taking constantly used oral contraceptives).
Intravaginal.
Vaginal capsules
Lying on your back, the capsule is inserted deep into the vagina 10 minutes before sexual intercourse. Duration of action — 4 hours. Be sure to enter a new capsule before each repeated sexual intercourse.
Vaginal tablets
Lying on your back, a tablet moistened with water is injected deep into the vagina for complete dissolution 10 minutes before sexual intercourse. The duration of the action is 3 hours. Be sure to introduce a new pill before each repeated sexual intercourse.
Vaginal cream
Attach the dispenser to the tube instead of the lid. Gently squeeze out the contents of the tube until the dispenser is filled (until the piston stops) so that no air bubbles form. Disconnect the dispenser from the tube. Close the tube with a lid. Lying on your back, insert the cream deep into the vagina with a dispenser, slowly pressing the plunger. Duration of action — 10 hours. Be sure to introduce a new dose of cream before each repeated sexual intercourse.
One dose (5 g of cream) is designed for one sexual act.
Vaginal suppositories
Lying on your back, the suppository is inserted deep into the vagina 5 minutes before sexual intercourse. Duration of action — 4 hours. Be sure to introduce a new suppository before each repeated sexual intercourse.
Intravaginal.
Vaginal tablets
Pre-released from the contour packaging, the tablet is injected deep into the vagina in a supine position 10 minutes before sexual intercourse, the duration of action is 3 hours. A single dose: 1 table. designed for 1 sexual act. It is mandatory to introduce a new vaginal pill in case of repeated sexual acts. The frequency of use is limited by the individual tolerance of the active substance and the frequency of sexual acts.
Vaginal suppositories
Having previously released the suppository from the contour packaging, it is injected deep into the vagina in a supine position 5 minutes before sexual intercourse, the duration of action is 4 hours. A single dose — 1 suppository is designed for 1 sexual act. It is mandatory to introduce a new vaginal suppository in case of repeated sexual acts. The frequency of use is limited by the individual tolerance of the active substance and the frequency of sexual acts.
Vaginal gel
The gel is injected into the vagina using a dispenser-applicator. Install the dosing device on the end of the tube. Fill it completely to the ring-shaped mark or to the stop of the piston so that no air bubbles form. Disconnect it from the piston. Before sexual intercourse, insert the gel deep into the vagina using a dosing device, slowly pressing the plunger. The introduction is easier to perform lying down. To retrieve the measuring device. the effect of the drug begins after 3 minutes and lasts for at least 6 hours. Be sure to introduce a new portion of the gel before each repeated sexual intercourse.
A single dose. 1 serving of gel is designed for 1 sexual act.
The frequency of use is determined by the tolerability of the drug and the frequency of sexual acts.
It is possible to use Benzalkonium chloride gel® together with a condom, a vaginal diaphragm, or an intrauterine device.
Intravaginal. Having previously released the tablet from the contour packaging, it is injected deep into the vagina in the "lying on your back" position 5 minutes before sexual intercourse, the duration of action is 4 hours. A single dose: 1 table. designed for 1 sexual act. It is mandatory to introduce a new vaginal pill in case of repeated sexual acts. The frequency of use is limited by the individual tolerance of the active substance and the frequency of sexual acts.
hypersensitivity to the components of the drug,
colpitis,
ulceration and irritation of the mucous membrane of the vagina and uterus.
Allergic reactions (burning, itching), contact dermatitis.
A local contraceptive (spermatocidal) agent, also has an antiseptic, antifungal, antiprotozoal effect, inactivates the virus Herpes simplex It exhibits bactericidal activity against staphylococci, streptococci, Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa, gonococci, proteus, Klebsiella, etc.)..), anaerobic bacteria, fungi and molds. It acts on strains of bacteria resistant to antibiotics and other chemotherapeutic drugs, suppresses plasmocoagulase and staphylococcal hyaluronidase. Spermatocidal action is due to the ability to damage the membranes of spermatozoa (at the beginning of the flagella, then the head), which makes it impossible to fertilize the damaged sperm. The effect develops 5 minutes after the introduction of the vaginal tablet. It is active in the prevention of sexually transmitted diseases (gonorrhea, chlamydia, trichomoniasis)
It does not affect the normal microflora of the vagina (including the Doderlein stick) and the hormonal cycle.
It is practically not absorbed during intravaginal administration, it is removed by simple washing with water and with physiological secretions.
Many drugs introduced intravaginally can reduce local spermicidal action (including Soaps and solutions containing it). Solutions of iodine (including 0.1% solution of iodonate) inactivate the drug.
