Benoxinate Hydrochloride 0.4%

Benoxinate Hydrochloride 0.4%

Oxybuprocaine

Local anesthesia in ophthalmology:

measurement of intraocular pressure (tonometry),

gonioscopy,

diagnostic scraping of the conjunctiva,

extraction of foreign bodies and sutures from the cornea and conjunctiva,

short-term surgical interventions on the cornea and conjunctiva.

Local, instill in the conjunctival sac 1 drop at a time. Long-term anesthesia (up to 1 h) is provided by three-time instillation of Benoxinate Hydrochloride 0.4%a at intervals of 4-5 minutes.

Individual hypersensitivity to the components of the drug.

Short-term tingling sensation, burning and hyperemia of the conjunctiva, allergic reactions, keratitis (rarely).

There are no data on drug overdose.

A local anesthetic that blocks nerve endings. It penetrates well into the tissues when applied topically. Compared to tetracaine and other local anesthetics, it has a less irritating effect on the conjunctiva and cornea.

Surface anesthesia of the conjunctiva and cornea occurs after 30 seconds and lasts for 15 minutes.

Benoxinate Hydrochloride 0.4% easily penetrates the corneal stroma after a single instillation into the conjunctival cavity. During the next 15 minutes, there is a quantitative decrease in the stromal concentration of the drug, which causes a 12-15-minute period of anesthesia with a single instillation.

• Local anesthetics
• Ophthalmic products

The literature does not describe the negative or positive effects of simultaneous administration of oxybuprocaine and other traditionally used eye drops into the conjunctival cavity.

It is noted that oxybuprocaine can theoretically reduce the antibacterial activity of sulfonamides.