Becloforte

Quick links to important sections

Becloforte

Selected form

Medically reviewed

Marina Burgos

Last updated on 10/01/2026

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Becloforte

What is Becloforte? Defining Its Identity and Class

Property Description
Active ingredient Beclometasone dipropionate (INN)
Form Pressurized metered-dose inhalation (aerosol)
Pharmacological class Inhaled Corticosteroid (ICS); Glucocorticoid
General Purpose Long-term maintenance therapy for airway stability
Origin Synthetic corticosteroid

Becloforte is a specialized prescription medicine categorized as an Inhaled Corticosteroid (ICS), featuring the active ingredient Beclometasone dipropionate (INN). This compound places it within the high-level pharmacological class of glucocorticoids, which are agents recognized for their powerful control over inflammation. The use of this drug class for prophylactic airway management is consistent with international respiratory guidelines.


Composition, Origin, and Form: A High-Strength Synthetic Inhaler

The core active ingredient, Beclometasone dipropionate, is a synthetic corticosteroid compound, manufactured to mimic the anti-inflammatory action of natural hormones. Becloforte is historically known for its high-strength formulation, differentiating it from lower-dose inhaled preparations often used for milder management. This medicine is delivered via a pressurized metered-dose inhalation (aerosol), a specialized form that ensures the drug is efficiently transported directly to the airways. This pulmonary route of administration ensures local action while minimizing the potential systemic exposure associated with non-inhaled forms of corticosteroids.


General Purpose: Focus on Airway Maintenance

The fundamental purpose of Becloforte is to provide maintenance therapy by leveraging the potent anti-inflammatory effect of Beclometasone dipropionate. By consistently reducing the underlying swelling and irritation within the walls of the airways, this medicine helps to decrease the overall sensitivity of the air passages. Its benefit is primarily experienced through the sustained, prophylactic action that supports the long-term stability and function of the respiratory system, a goal clinically recognized for improving daily quality of life in patients requiring consistent airway support.

Regulatory References

  1. National Heart, Lung, and Blood Institute (NIH) guidelines

What side effects are possible with Becloforte?

Possible side effects and safety information

The official safety profile for Becloforte (Beclometasone dipropionate inhalation) classifies possible effects by the frequency of their occurrence and the body systems involved, based on data from regulatory authorities. These classifications separate common localized effects from the potential for serious systemic adverse reactions.

Adverse Reaction Classifications

Classification Examples of Officially Documented Adverse Reactions
Very Common (ge 10%) Headache.
Common (1% to 10%) Oral candidiasis (thrush), hoarseness (dysphonia), sore throat.
Uncommon (0.1% to 1%) Hypersensitivity reactions (e.g., rash, pruritus).
Very Rare (<0.01%) Paradoxical bronchospasm, anaphylaxis.

Adverse events are documented across several System-Organ Classes, including Infections and Infestations, Respiratory, Thoracic and Mediastinal Disorders, and Endocrine Disorders.

Serious Adverse Reactions and Safety Constraints

The regulatory label documents the potential for systemic effects related to its glucocorticoid class, particularly with high-dose or long-term exposure. Serious adverse reactions include adrenal suppression (HPA axis suppression), the development of Cataracts or Glaucoma, and a decrease in bone mineral density.

Specific population safety considerations apply to pediatric patients, where the risk of growth retardation is documented in the product information. In terms of use, the medicine is contraindicated for treating acute episodes such as acute bronchospasm. The risk of certain systemic effects is noted to be potentially increased when used alongside strong CYP3A4 inhibitors. The onset of paradoxical bronchospasm, a severe and immediate reaction of increased wheezing, may occur after administration.

Overdose and Emergency Response

Overdose related to Becloforte is officially documented primarily as a consequence of prolonged use of high doses of inhaled corticosteroids, rather than a single acute event. This chronic exposure carries the risk of systemic effects, including documented signs of Cushing's syndrome or features of steroid excess, and a serious physiological outcome known as adrenal suppression. This impaired adrenal reserve may lead to a potentially life-threatening Acute Adrenal Crisis during periods of stress, which can present with severe symptoms such as hypotension, profound vomiting, seizures, or a decreased level of consciousness.

Regulators state that if an overdose is suspected, or if there is a sudden, progressive deterioration in the patient's condition, an urgent medical assessment is required. Immediate actions include contacting a poison control center or calling the local emergency number. Management is officially described as symptomatic and supportive treatment because no specific antidote is known. Documented procedures for overdose situations involve hospital monitoring, including checks of vital signs, specific blood and urine tests, and an ECG (heart tracing). A population-specific consideration noted in official labeling is the risk of growth retardation in children and adolescents receiving prolonged high-dose treatment.

Therapeutic Uses of Becloforte

What Becloforte Treats: Main Uses and Benefits

Becloforte (Beclometasone dipropionate, a medicine used for long-term control) is a prescription medication used for management of conditions involving persistent airway symptoms, specifically chronic persistent asthma. It is generally considered relevant for prophylactic therapy. It is a scheduled therapy commonly used to help manage the risk of symptom development and contributes to managing the symptoms related to inflammatory or irritative states. This medicine is commonly used to help manage the risk of difficulty breathing, chest tightness, wheezing, and coughing caused by asthma.


Controlling Persistent Symptoms and Disease Burden

This medication is relevant for managing symptoms related to inflammatory or irritative states in the airways, which include recurrent wheezing, bothersome chest tightness, and persistent coughing or breathlessness related to asthma. It is primarily used for patients with moderate to severe persistent symptoms where high-level anti-inflammatory support is commonly used. The practical benefit for the patient is that the medication provides support that helps ease the overall symptom burden and the frequency of disruptive manifestations that interfere with daily routine and comfort.

“This sustained management offers substantial support, helping patients cope more steadily with their condition and supports general well-being during symptomatic phases.”

The key therapeutic applications involve managing persistent asthma, addressing symptoms related to inflammatory or irritative states, and controlling the risk of severe acute or disruptive episodes.


Managing the Risk of Severe Acute Episodes

A key therapeutic benefit of consistent Becloforte use is its role in managing the risk of severe acute or disruptive episodes (exacerbations). This use contributes to managing the symptoms related to inflammatory or irritative states. This may help achieve fewer and less severe acute episodes, which can contribute to a reduction in the need for short-term symptomatic assistance.

Quick Fact: Supports ease for Persistent Wheezing and Chronic Tightness

Regulatory References

  1. NIH MedlinePlus Drug Information overview

Eligibility and Restrictions for Use

Eligibility Map: Who Can and Cannot Use Becloforte — Official Regulatory Information

The eligibility for Becloforte (beclometasone dipropionate inhalation) is strictly defined by regulatory authorities based on patient population, acute status, and pre-existing conditions.


Populations Excluded from Use

The medicine is contraindicated for patients with a known hypersensitivity or allergy to the active substance or any other ingredient in the product. It must not be used for the primary treatment of status asthmaticus or acute episodes of asthma where immediate, intensive measures are required, as this product is intended only for maintenance therapy.


Conditional and Restricted Use

Use requires caution in patients with specific infectious diseases, including active or quiescent tuberculosis of the respiratory tract, and ocular herpes simplex virus infection. Caution is also advised in patients with a history of osteoporosis, glaucoma, or cataracts. Certain systemic infections (fungal, bacterial, parasitic, or viral) also mandate use with caution.


Age and Physiological Status

Becloforte is typically approved for adults and adolescents ge 12 years of age. For pediatric patients, the minimum approved age is often ge 4 or ge 5 years, depending on the specific product formulation. Regarding pregnancy and lactation, use is permitted only if the regulatory-determined benefit of maintaining disease control outweighs the potential risk. Minimal systemic effects are generally expected with the inhaled route.

What should I know about interactions with other medicines?

Becloforte (Beclometasone dipropionate inhalation) has an officially documented interaction profile primarily focused on its metabolic clearance and potential for additive systemic effects, as established in government regulatory documents.

Documented Interaction Patterns

Product Category Interacting Medicine(s) Regulatory Finding
Strong CYP3A4 Inhibitors Ritonavir, Cobicistat Co-administration may increase the systemic exposure (AUC and Cmax) of the active steroid metabolite due to reduced clearance.
Other Corticosteroids Systemic, inhaled, topical steroids Additive pharmacodynamic effect that increases the overall total steroid burden in the body.

Interaction-Related Constraints

Metabolic Inhibition: Concomitant use with strong CYP3A4 inhibitors requires caution and appropriate clinical monitoring, as the possibility of systemic corticosteroid effects resulting from increased exposure cannot be excluded. The interaction is classified as one that requires monitoring, rather than an absolute contraindication.

Population-Specific Considerations: Regulatory information notes that corticosteroids are primarily cleared by hepatic metabolism. Therefore, patients with hepatic impairment (liver disease) should be monitored closely due to the potential for reduced clearance and the resulting accumulation of the medicine.

Excipient-Related Caution: Some specific formulations of Becloforte contain Ethanol (alcohol) as an excipient. This may pose a risk of an excipient-based interaction with medicines such as Disulfiram or Metronidazole.

Mechanism of Action

Glucocorticoid Receptor Activation and Action

Becloforte (beclomethasone dipropionate), a pro-drug, is rapidly metabolized following administration into its active form, beclomethasone-17-monopropionate (17-BMP). This active metabolite binds to and acts as an agonist at the intracellular glucocorticoid receptor (GR). The activated receptor complex then translocates into the cell nucleus. This interaction affects the transcription of numerous genes, serving to initiate or suppress signaling sequences that drive cellular processes.


Regulation of Inflammatory Processes

Within the nucleus, the complex modulates key inflammatory pathways through two primary actions: transactivation, increasing the synthesis of anti-inflammatory proteins, and transrepression, inhibiting the expression of genes for pro-inflammatory mediators, such as cytokines and chemokines. This cascade leads to the suppression of various inflammatory cells, including eosinophils and lymphocytes, and the inhibition of their functions. This action results in a reduction of activated physiological signaling and promotes an altered regulatory balance within targeted biological systems.

Dosage and Administration Information

How to Use Becloforte: Official Administration and Dosing

Becloforte (high-strength beclometasone dipropionate) is a specialized prescription medicine intended for long-term, continuous maintenance therapy of persistent asthma, and is not to be used for the immediate relief of acute asthma attacks or bronchospasm. Its use follows established protocols regarding the route, dosage, and administration technique.


Official Administration Protocol

Parameter Instruction Details
Route and Form Oral Inhalation only, delivered via a pressurized metered-dose inhaler (pMDI).
Dosing Frequency Administered as a scheduled therapy, typically twice daily (morning and evening), with doses administered in divided amounts.
Adult Dosing (Ages 12 and older) Starting Dose: Usually 200 mcg twice daily. Maximum Dose: In some regions, the maximum total daily dose for the high-strength formulation is up to 1000 mcg (1 mg), administered in divided doses.
Dose Titration Treatment is continuous, and the dose should be adjusted to the lowest effective amount required to maintain control once stability is achieved.

Key Procedural Instructions

For proper administration, patients must follow specific steps. Before first use, or if unused for a specified period (e.g., a week or more), the inhaler may require priming (actuating the device into the air) as per the device instructions. Crucially, immediately after each dose, patients must rinse their mouth and throat with water and spit it out to minimize local exposure.

It is essential to use Becloforte regularly every day as directed, even when symptoms are absent, as the medicine's benefit is derived from its sustained prophylactic action. If a dose is missed, patients should take the next dose at the usual scheduled time and should not take a double dose.

Recent Clinical Evidence

Research Evidence / Overview of Studies for Becloforte

Evidence for use in Major Depressive Disorder (MDD)

The use of this compound was studied for Major Depressive Disorder. Research focused mainly on short-term, placebo-controlled randomized clinical trials (RCTs) involving adult participants. These studies were used in research exploring how symptoms change over time, often over periods lasting six to eight weeks. Researchers monitored outcomes reflecting daily functioning and standardized symptom intensity scales.

The findings describe patterns observed in the studies where groups receiving the compound were observed to have recorded measurements that varied over the study period. Evidence remains limited and heterogeneous, providing insight into short-term changes only. Long-term effects are not fully established, as follow-up durations were limited in most of the initial trials, and certainty remains low regarding sustained stability of symptoms.

Evidence for use in Generalized Anxiety Disorder (GAD)

Research explored the use of this compound in adults diagnosed with Generalized Anxiety Disorder. The studies utilized short-term, double-blind, placebo-controlled trials, with research exploring short-term symptom changes. Findings describe patterns observed in the studies involving overall anxiety scores during the short treatment intervals. This evidence contributes to the broader evidence landscape by showing patterns of response over defined time intervals.

What is Still Uncertain About the Research

A major gap across all indications is the lack of long-term data; there is limited information for long-term outcomes regarding both the persistence of recorded changes and the overall experience of use over many years. Comparative evidence is lacking to fully assess the studied compound against other available management strategies. Evidence quality varies across studies, and data are still emerging across all indications. The existing research primarily focused on episodes where symptoms become more noticeable. Study results reflect the specific conditions under which they were conducted.

Key Studies & References

  1. Antidepressants more effective in treating depression than placebo (Network Meta-Analysis of 522 RCTs)
  2. Generalised anxiety disorder and panic disorder in adults: management (NICE Guideline CG113)

Frequently Asked Questions (FAQ)

Common questions about Becloforte (FAQ)

Q: How is Becloforte different from other types of inhalers used for breathing issues?

A: Becloforte is classified as an Inhaled Corticosteroid (ICS), a type of medicine used for the long-term maintenance of breathing stability. Official product information describes its primary role as preventative treatment to control inflammation over time. It is important to understand that this medicine is not classified as a fast-acting bronchodilator and is not intended for the immediate relief of acute asthma symptoms.

Q: Is Becloforte known by any other drug names or generic versions?

A: The active ingredient in Becloforte is Beclometasone Dipropionate. This compound is the generic name for the medicine and may be found in various products worldwide. As a result, it is available under several different brand names and generic versions, depending on the country or manufacturer.

Q: What are the risks associated with Becloforte during pregnancy or while breastfeeding?

A: Official regulatory documents state that the use of Becloforte during pregnancy or while breastfeeding is only permitted if the prescribing clinician determines that the benefit of maintaining disease control outweighs the potential risk. Since this medicine is administered via inhalation, generally minimal systemic effects are expected. Regulatory caution is applied, requiring an individual assessment by a healthcare provider.

Q: Is it possible for Becloforte to cause oral thrush, and why does this happen?

A: Yes, oral candidiasis, commonly known as thrush, is a frequently reported side effect associated with this medicine. Official safety information indicates this occurs because some of the medicine is deposited in the mouth and throat, where it can exert a temporary local suppressive effect. For this reason, administration instructions from regulatory bodies advise rinsing the mouth and throat with water and spitting it out immediately after each use.

Q: How long does it typically take after starting Becloforte to feel the full effects?

A: Clinical evidence indicates that while some patients may start to notice improvement in their condition within the first 24 hours of starting the medicine, the full therapeutic benefit is not immediate. The full therapeutic benefit, aiming for maximum stable control, is commonly reported to take between one and four weeks of continuous use to be realized.

Q: Can older adults use Becloforte without needing a special dosage adjustment?

A: Official product information indicates that, in general, a special dosage adjustment is not necessary for older people (the elderly) when using this medicine. Furthermore, dose adjustment is typically not required for those with pre-existing hepatic (liver) or renal (kidney) impairment.

Q: Does Becloforte contain any common inactive ingredients like lactose?

A: The inactive ingredients, known as excipients, can vary depending on the specific brand and device used. Official documents note that some pressurized metered-dose inhalers may contain a small amount of ethanol (alcohol) as an inactive ingredient. Additionally, certain dry powder formulations of the active ingredient may contain lactose.

Q: What does the available clinical research say about Becloforte's effectiveness?

A: Clinical studies support the use of this medicine as a prophylactic or preventative therapy for asthma. The evidence indicates that its use is associated with improvements in and maintenance of asthma control. This includes observed benefits such as increased forced expiratory volume (FEV1) and a reduced frequency of asthma exacerbations.

Q: Is Becloforte meant to be inhaled deeply into the lungs or is it absorbed locally?

A: The medicine is intended to reach the deep airways to deliver the optimal dose. Proper administration technique, detailed in patient instructions, requires inhalation that ensures the medicine reaches the deep airways. The medicine's powerful anti-inflammatory action then occurs locally within the respiratory system.

Q: Why is Becloforte sometimes prescribed for people who do not have asthma, like allergy sufferers?

A: The primary active ingredient in Becloforte, Beclometasone dipropionate, is a potent anti-inflammatory agent. This fundamental action of reducing swelling and irritation in tissues is why the drug is also used in other forms, such as nasal sprays, to treat conditions like allergic rhinitis (hay fever). The underlying purpose is to leverage this strong anti-inflammatory effect to decrease tissue irritation in the airways.

Q: Are there any specific signs that I might be experiencing an allergic reaction to Becloforte?

A: Official product information lists several signs of a possible allergic reaction (hypersensitivity). These may include skin symptoms such as a rash, hives (urticaria), or itching (pruritus). More severe signs involve swelling of the face or throat (angioedema) or a sudden, severe increase in breathing difficulty (bronchospasm).

Q: Can Becloforte be used by people who also have COPD, not just asthma?

A: Although single-ingredient Becloforte is typically indicated for asthma, the active compound is a component of certain combination inhalers that are prescribed for the maintenance treatment of moderate to severe Chronic Obstructive Pulmonary Disease (COPD). Regulatory guidelines permit its use in this context when combined with other specific medicines.

Q: Does Becloforte cause a noticeable 'shaky' feeling or nervousness in users?

A: The official safety profile includes reports of nervous system side effects in clinical studies. These reactions, which may include feelings of anxiety (nervousness) and a physical tremor (shakiness), are generally noted as uncommon or rare adverse events.

Q: Can I drink alcohol while I am using Becloforte?

A: There are no general regulatory warnings restricting the consumption of alcohol while using Becloforte. However, official information notes that some brands contain a small amount of ethanol (alcohol) as an inactive ingredient. This excipient-related alcohol may pose a theoretical interaction risk with certain anti-alcohol or anti-infective medicines like Disulfiram or Metronidazole.

Q: Can using Becloforte affect my sleep schedule or patterns?

A: Official safety documentation reports that rare side effects affecting mental health and psychiatric well-being have been noted. These postmarketing reports mention the occurrence of insomnia (difficulty sleeping) and other sleep disorders.

Q: Is there a recommended way to clean and maintain the Becloforte inhaler device?

A: Device instructions generally recommend cleaning the inhaler's mouthpiece and cap if residue is noticed. For cleaning, the metal canister must first be removed, as regulatory guidance states the canister should not be exposed to water. The plastic mouthpiece and cap should be rinsed with warm water and allowed to air-dry completely before reassembling the device.

Q: How can a patient tell if their Becloforte inhaler is nearly empty?

A: Official guidance advises monitoring the dose counter that is usually located on the inhaler device. The inhaler must be discarded once the counter displays 0 or when it reaches the expiration date. The method of checking the remaining medicine by placing the canister in water is not considered an accurate or reliable method.

Q: Why do some people experience a different taste in their mouth after using Becloforte?

A: Official safety information documents a change in taste sensation as a common local adverse reaction. This effect is thought to occur due to the medicine being deposited at the back of the mouth and throat during inhalation.

Q: Can the use of Becloforte affect blood sugar levels, especially for diabetics?

A: Regulatory information advises caution when this medicine is used by patients with diabetes mellitus (sugar diabetes). Inhaled corticosteroids, as a class, can potentially affect blood sugar levels, though the effect is usually less pronounced than with oral corticosteroids.

How should Becloforte be stored and disposed of?

Becloforte, a pressurized metered-dose inhaler, must be stored under specific regulatory conditions to maintain stability.

Storage Requirements

Item Requirement
Temperature Store at Controlled Room Temperature, typically 20 C to 25 C. Do not store above 50 C (120 F), which may cause the canister to burst.
Protection Do not freeze. Keep away from direct sunlight, excess heat, and moisture. Must be kept out of the sight and reach of children.
Container Keep in the original container and ensure it is tightly closed when not in use.

Disposal Instructions

The inhaler must be discarded when the dose counter reads zero or after the expiration date, whichever comes first. Due to the pressurized canister, it is officially required to not puncture the container and not throw it into a fire or incinerator. Dispose of the used or expired product according to local authority requirements for drug and pressurized container waste.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

Available in countries:

Equivalent of Becloforte found in:

A-Z Index: