Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 2020-04-03
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BAZUKAâ„¢ TREATMENT GEL
Salicylic Acid 12.0% w/w; Lactic Acid 4.0% w/w.
Clear, colourless, collodion-like gel.
For the topical treatment of warts, verrucas, corns and calluses.
For adults, the elderly and children over 2 years:
Children under 12 should be treated under adult supervision and treatment of infants less than 2 years is not recommended.
Bazuka Treatment Gel should be applied once daily. The gel should be applied to the wart, verruca, corn or callus every night. Treatment can take up to twelve (12) weeks for resistant lesions to disappear, and it is necessary to persevere with the treatment.
1. Every night, soak the affected site in warm water for 2 to 3 minutes.
2. Dry thoroughly with the patient's own towel; this towel should be used for the affected site(s) only.
3. Carefully apply one or two drops of the gel to the lesion and allow to dry over its surface. Take care to avoid spreading on to surrounding normal skin. No adhesive plaster is necessary.
4. The following evening, carefully remove and discard the elastic film formed from the previous application. Repeat steps 1 to 3 to reapply the gel. Hands should be washed after touching the wart or verruca. Occasionally, if removal of the elastic film proves difficult, carefully reapply the gel over it and allow to dry. This should help thicken the film to assist removal. If necessary, such re-application may be made on two or three successive days.
5. The wart, verruca, corn or callus may take up to twelve (12) weeks to disappear and it is important to persevere with the treatment.
6. If the wart/verruca has not disappeared after about 12 weeks of treatment, further advice should be sought from a doctor or pharmacist.
7. At the end of treatment, if the elastic film is difficult to remove, it may be allowed to remain on the skin until it sheds.
Not to be used on or near the face, intertriginous or anogenital regions, or by diabetics or individuals with impaired peripheral blood circulation.
Not to be used on moles, birthmarks, hairy warts or on any other skin lesions for which the gel is not indicated. Not to be used in cases of sensitivity to any of the ingredients.
Keep away from the eyes, mucous membranes and from cuts and grazes.
The gel should be applied carefully to the wart, verruca, corn or callus only, to avoid possible irritation of surrounding normal skin.
Do not use excessively.
Some mild, transient irritation may be expected, but in cases of more severe or persistent pain/irritation, the treatment should be suspended and/or discontinued. See also section â€œUndesirable Effectsâ€.
Avoid inhaling vapour, and keep cap firmly closed when not in use.
Contact with clothing, fabrics, plastics and other materials may cause damage, and should be avoided.
For external use only.
Keep all medicines out of the reach of children.
Bazuka Treatment Gel may be irritant in certain patients, which in rare instances may appear as a temporary blemish on the skin. See also section â€œSpecial Warnings and Precautions for Useâ€.
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.
Any excessive use of Bazuka Treatment Gel could cause irritation of the skin. If this occurs, Bazuka Treatment Gel should be used more sparingly or applied less frequently.
The active ingredients, salicylic acid and lactic acid, are well-established pharmacopoeial substances. In combination, they are routinely used in the treatment of warts, verrucas, corns and calluses for their keratolytic properties.
When applied topically, and in high enough concentrations, salicylic acid acts by achieving a slow, painless destruction of the thickened stratum corneum. It softens and destroys the stratum corneum of the affected tissue by reducing the adhesiveness of the corneocytes while causing the cornified epithelium to swell, soften, macerate and finally desquamate. In the treatment of warts, a mild irritant reaction, which may render the virus more prone to immunologic stimulation or response, may add to the mechanical removal of infected cells. The other active ingredient, lactic acid, enhances the availability of the salicylic acid from the dried collodion, in addition to having antiseptic and caustic properties.
Bazuka Treatment Gel presents 12% salicylic acid and 4% lactic acid in an evaporative collodion-like gel which forms a cohesive and adhesive film on the skin.
The formulation is presented in a collapsible aluminium tube fitted with a special applicator nozzle allowing the formulation to be dispensed precisely to the affected areas only. This minimises the spread of the preparation onto the surrounding healthy skin, which could otherwise lead to inflammation, irritation and poor patient compliance.
The film-forming characteristics of the collodion-like gel vehicle also offer distinct advantages in clinical usage. The gel quickly forms a surface film, well before it dries completely, thereby prolonging the period during which the keratolytic solution can properly infiltrate and achieve intimate contact with the surface layers of the thickened stratum corneum.
Furthermore, even when the film appears to have dried completely, the inclusion of the non-evaporative lactic acid ensures that a proportion of the salicylic acid remains in solution within the vehicle, thus permitting continued release of the keratolytic, which may otherwise be entrapped within the collodion-like film.
Systemic absorption of salicylic acid or lactic acid after application of the recommended daily dose of one or two drops of the preparation to small, circumscribed areas is exceedingly unlikely.
No special information.
Camphor; Pyroxylin; Ethanol; Ethyl Acetate.
Highly flammable - keep away from flames.
Do not store above 25°C.
Collapsible tube containing 6g, complete with special applicator, emery board and instructions. This is supplied as an original pack (OP).
Diomed Developments Limited
Tatmore Place, Gosmore
Hitchin, Herts SG4 7QR, UK
29 July 2008.