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Medically reviewed by Oliinyk Elizabeth Ivanovna, PharmD. Last updated on 19.05.2022
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Benzydamine hydrochloride relieves the pain and discomfort of a variety of ulcerative conditions. It has some topical anti-inflammatory and analgesic (pain killing) effects.
Azilsartan is an angiotensin II receptor antagonist. Azilsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
Azilsartan is used to treat high blood pressure (hypertension).
Azilsartan may also be used for purposes not listed in this medication guide.
Usual Adult Dose for Hypertension
80 mg orally once a day
Comments: Consider a starting dose of 40 mg orally once a day for patients on high diuretic doses.
Renal Dose Adjustments
No adjustment recommended
Liver Dose Adjustments
Mild to moderate liver dysfunction: No adjustment recommended
Severe liver dysfunction: Unknown
Precautions
US BOXED WARNING:
-FETAL TOXICITY: If pregnancy is detected, discontinue this drug as soon as possible. Drugs that act directly on the renin angiotensin system (RAS) can cause injury and death to the developing fetus.
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice: Administer with or without food.
Monitoring: Assess renal function and serum electrolytes prior to initiating therapy and periodically during treatment.
Patient advice:
-Females of childbearing age should be informed of the consequences of exposure to this drug during pregnancy; ask these patients to report pregnancies as soon as possible.
-Encourage patients to report any lightheadedness that may occur during treatment initiation and to stop taking this drug until consulting a physician if syncope occurs.
-Dehydration may lead to excess blood pressure reduction; inform patients to contact their healthcare provider if they experience excessive perspiration, vomiting, or diarrhea.
See also:
What is the most important information I should know about Azilsartan?
Benzydamine hydrochloride oral rinse is not suitable for use in children under 12 years. The spray can be used in children at a dose of up to 1 puff per 4kg of body weight (under 6) or 4 puffs (6-12 years) every 1.5 - 3 hours.
Use Azilsartan medoxomil as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Azilsartan medoxomil. Talk to your pharmacist if you have questions about this information.
- Take Azilsartan medoxomil by mouth with or without food.
- Taking Azilsartan medoxomil at the same time each day will help you remember to take it.
- Take Azilsartan medoxomil on a regular schedule to get the most benefit from it.
- Continue to take Azilsartan medoxomil even if you feel well. Do not miss any doses.
- If you miss a dose of Azilsartan medoxomil, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Azilsartan medoxomil.
See also:
What are the possible side effects of Azilsartan?
Applies to Azilsartan medoxomil: oral tablet
In addition to its needed effects, some unwanted effects may be caused by Azilsartan medoxomil. In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking Azilsartan medoxomil:
Rare
- Blurred vision
- confusion
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- sweating
- unusual tiredness or weakness
Minor Side Effects
Some of the side effects that can occur with Azilsartan medoxomil may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Less common:
- Diarrhea
- Cough
- dizziness
- lack or loss of strength
- muscle spasm
- nausea
Azilsartan medoxomil is an angiotensin II receptor antagonist indicated for the treatment of mild to moderate essential hypertension. Azilsartan medoxomil is a prodrug of Azilsartan marketed as "Edarbi" by Takeda. Azilsartan medoxomil has so far been shown to be superior to olmesartan and valsartan in lowering blood pressure.