Medically reviewed by Fedorchenko Olga Valeryevna, PharmD. Last updated on 2022-06-26
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Use Anesket as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Anesket is usually administered as an injection at your doctor's office, hospital, or clinic by those experienced in administering general anesthetics, in maintaining an airway, and in controlling respiration.
- Do not use Anesket if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
- If you miss a dose of Anesket, contact your doctor right away.
Ask your health care provider any questions you may have about how to use Anesket.There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
Use: Labeled Indications
Anesthesia: Induction and maintenance of general anesthesia
Off Label Uses
Data from a limited number of patients in open-label, prospective clinical trials suggest that Anesket may be beneficial for the treatment of severe agitation and violent behavior. However, the dosage range varies considerably and an optimal dosage has not been established. Additional data is necessary to further define the role of Anesket in this condition. Since there is limited data on the safety and efficacy of Anesket in this setting, the Neurocritical Care Society recommends reservation of Anesket for patients who do not respond to more frequently recommended antiepileptic drug treatment.
Prolonged recovery time may occur if barbiturates and/or narcotics are used concurrently with Anesket.
Anesket is chemically incompatible with barbiturates and diazepam because of precipitate formation. Therefore, these should not be mixed in the same syringe or infusion fluid.
Anesket may potentiate the neuromuscular-blocking effects of atracurium and tubocurarine including respiratory depression with apnoea.
The use of halogenated anaesthetics concomitantly with Anesket can lengthen the elimination half-life of Anesket and delay recovery from anaesthesia. Concurrent use of Anesket (especially in high doses or when rapidly administered) with halogenated anaesthetics can increase the risk of developing bradycardia, hypotension or decreased cardiac output.
The use of Anesket with other CNS depressants (eg, ethanol, phenothiazines, sedating H1-blockers or skeletal muscle relaxants) can potentiate CNS depression and/or increase risk of developing respiratory depression. Reduced doses of Anesket may be required with concurrent administration of other anxiolytics, sedatives and hypnotics.
Anesket has been reported to antagonise the hypnotic effect of thiopental.
Patients taking thyroid hormones have an increased risk of developing hypertension and tachycardia when given Anesket.
Concomitant use of antihypertensive agents and Anesket increases the risk of developing hypotension.
When Anesket and theophylline are given concurrently, a clinically significant reduction in the seizure threshold is observed. Unpredictable extensor-type seizures have been reported with concurrent administration of these agents.
Incompatibilities: Anesket is chemically incompatible with barbiturates and diazepam because of precipitate formation. Therefore, these should not be mixed in the same syringe or infusion fluid.