Medically reviewed by Oliinyk Elizabeth Ivanovna, PharmD. Last updated on 2020-03-12
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Top 20 medicines with the same components:
Hyperuricemia of various origins, gout.
Inside, 1-3 tables. on the day after meals, with the obligatory use of at least 1.5-2 liters of liquid per day (under the control of diuresis). Treatment should begin with 1 table. daily with a gradual increase in the dose.
Hypersensitivity, hemochromatosis, severe renal impairment (with serum creatinine levels above 132.6 µmol / L (1.5 mg / 100 ml) or with glomerular filtration rate below 40 ml / min), pregnancy, breastfeeding, age (under 14 years).
Gastrointestinal disorders, diarrhea, vasculitis with skin manifestations and fever, liver and kidney damage, changes in the blood picture (leukopenia, thrombocytopenia), allergic reactions.
- Agents that affect the metabolism of uric acid
Increases the toxicity of azathioprine and mercaptopurine, the anticoagulant effect of coumarin derivatives, prolongs the effect of chlorpropamide, thiazide diuretics, etacrine and salicylic acid derivatives reduce the effect (increase the level of uric acid in the serum). When treated with iron preparations, it increases the accumulation of iron in the liver.