Aeronid (ANALGESICS) (Budesonide) Side Effects

Budesonide is a corticosteroid available in various forms to treat a range of conditions. Side effects can vary depending on the specific formulation, dosage, and your individual body's response.

Side Effects Across All Formulations

While budesonide is a corticosteroid with low systemic bioavailability (meaning less of it is absorbed into your bloodstream), systemic side effects are still possible, especially with long-term use of high doses.

Common side effects that may occur with any form of budesonide:

Gastrointestinal issues: Nausea, abdominal pain, diarrhea, constipation.
Headache.
Respiratory infections.
Fungal infections: Particularly oral thrush (candidiasis) with inhaled use.
Mood and behavioral changes: Irritability, anxiety, depression, sleep disturbances.
Allergic reactions: Skin rash, itching, hives (rare).
Skin problems: Skin thinning, bruising, delayed wound healing.
Eye problems: Cataracts, glaucoma (with prolonged systemic use).
Osteoporosis (decreased bone density) with prolonged systemic use.
Adrenal suppression (with prolonged systemic use or abrupt discontinuation).

Side Effects by Formulation

1. Inhaled Forms (inhalation powder, suspension for inhalation/nebulizer):

Used for treating asthma and chronic obstructive pulmonary disease (COPD).

Common:
- Throat irritation, cough.
- Hoarseness (dysphonia).
- Oral and pharyngeal fungal infections (candidiasis) – to minimize this risk, it's recommended to rinse your mouth with water after each inhalation.
Rare:
- Bronchospasm (increased shortness of breath after inhalation).
- Systemic effects (see above), which are more likely with high doses or prolonged use, especially in children.

2. Nasal Sprays (for intranasal use):

Used for treating allergic rhinitis and nasal polyps.

Common:
- Nasal irritation, dryness.
- Nosebleeds (epistaxis).
- Sneezing.
- Headache.
Rare:
- Nasal septal perforation (very rare, with improper use or prolonged application).
- Nasal fungal infections.
- Systemic effects, extremely rare due to minimal absorption.

3. Delayed-Release Capsules / Tablets (for oral use):

Used for treating Crohn's disease, ulcerative colitis (when localized in the large intestine), and autoimmune hepatitis.

Common:
- Headache.
- Nausea, abdominal pain, dyspepsia (indigestion).
- Sleep disturbances.
- Acne.
- Weight gain.
- Mood swings.
Less common/rare (systemic effects, more pronounced than with other forms, but less severe than with traditional systemic corticosteroids):
- Cushing's syndrome (moon face, abdominal fat deposition, thin limbs).
- Osteoporosis.
- Increased blood pressure.
- Decreased blood potassium levels.
- Increased blood sugar levels.
- Adrenal suppression.

4. Rectal Forms (foam, suppositories, enemas):

Used for treating ulcerative colitis, especially when affecting the rectum and sigmoid colon.

Common:
- Local irritation, burning, or pain in the rectum.
- Nausea, bloating.
- Headache.
Rare:
- Systemic effects, extremely rare due to limited local action and low absorption.

What to do if Side Effects Occur?

If you experience any side effects, it's important to consult your doctor. Do not try to change your dosage or stop taking the medication on your own, as this could worsen your underlying condition or lead to withdrawal symptoms.

Frequently Asked Questions:

What should I do if I get oral thrush after using an inhaler?
- Notify your doctor immediately. Antifungal treatment may be necessary. To prevent thrush, always rinse your mouth thoroughly with water (without swallowing) after each budesonide inhalation.
Can budesonide cause weight gain?
- Yes, with oral use, especially long-term, weight gain is possible as it's one of the systemic effects of corticosteroids. With inhaled or nasal forms, this effect is extremely unlikely.
Is it normal to have a headache after taking budesonide?
- Headache is one of the common side effects of budesonide, particularly with oral use. If your headache is severe or persistent, contact your doctor.
What if I miss a dose?
- Take the missed dose as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.
Can I stop taking budesonide abruptly?
- No, absolutely not. This is especially true for oral forms and long-term use. Abrupt discontinuation can lead to corticosteroid withdrawal syndrome (weakness, nausea, vomiting, low blood pressure) and a flare-up of your underlying condition. Your doctor must gradually reduce the dosage.
Does budesonide affect growth in children?
- With prolonged use of high-dose inhaled budesonide, a slight slowing of growth rate in children is possible. Your doctor will monitor this closely. Systemic effects on growth are more pronounced with oral use.
How long can I take budesonide?
- The duration of treatment is determined by your doctor based on your condition and the formulation. Some conditions require long-term maintenance therapy.

Aeronid (ANALGESICS)

Aeronid (ANALGESICS)

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