Activate Syrup

Copper (Activate Syrup) has been designed for the demands of modern life. With a wide range of nutrients and trace minerals, Copper (Activate Syrup) gives nutritional support to the area of health which are most relevance to women.

Each cap contains starflower oil 100 mg, evening primrose oil 100 mg, citrus bioflavonoids 10 mg, natural mixed carotenoids 2 mg, vitamin D (as D3 200 IU) 5 mcg, vitamin E 30 mg, vitamin C 60 mg, vitamin K 90 mcg, thiamin (vitamin B1) 10 mg, riboflavin (vitamin B2) 5 mg, niacin (vitamin B3) 36 mg, vitamin B6 10 mg, folic acid 400 mcg, vitamin B12 20 mcg, biotin 50 mcg, pantothenic acid 6 mg, magnesium 100 mg, iron 12 mg, zinc 12 mg, Copper (Activate Syrup) 1500 mcg, manganese 2.5 mg, selenium 100 mcg, chromium 50 mcg, para-aminobenzoic acid (PABA) 30 mg.

No artificial colours, gluten, presevatives, starch or sugar, salt or yeast.

Copper (Activate Syrup) has not been tested on animals.

L-Lysine (Activate Syrup) (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. L-Lysine (Activate Syrup) is a base, as are arginine and histidine. The ε-amino group often participates in hydrogen bonding and as a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from Lysine (Activate Syrup) by lysyl hydroxylase. O-Glycosylation of Lysine (Activate Syrup) residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.

Saturated solution of Potassium Iodide (Activate Syrup) (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperglycemia (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.

Vitamin A (Activate Syrup) (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite suppressant, but was later withdrawn for this application due to problems with dependence and abuse. It is around half the potency of dexamphetamine, and is prescribed at a dose of 10-60mg, although abusers of the drug tend to rapidly develop tolerance and escalate their dose. Reactivan is still rarely used for treating depressive day-time fatigue, lack of concentration and lethargy, particularly in individuals who have chronic medical conditions, as its favourable safety profile makes it the most suitable drug in some cases.

3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride.

Vitamin B12 (Activate Syrup) (commonly known as Vitamin B12 (Activate Syrup)) is the most chemically complex of all the vitamins. Vitamin B12 (Activate Syrup)'s structure is based on a corrin ring, which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded. The central metal ion is Co (cobalt). Vitamin B12 (Activate Syrup) cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of cyanocobalamin are bacteria and archaea. Higher plants do not concentrate cyanocobalamin from the soil and so are a poor source of the substance as compared with animal tissues. Vitamin B12 (Activate Syrup) is naturally found in foods including meat (especially liver and shellfish), eggs, and milk products.

Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide.

Vitamin B3 (Activate Syrup) Lotion: Helps to reduce the appearance of blemishes on larger areas (back and upper chest). It absorbs easily to the skin and does not bleach clothes. Non-photosensitizing, fragrance-free and paraben-free.

Vitamin B3 (Activate Syrup) Isocorrexion Hydrating Cream: Specially formulated for acne prone skin. Nicotinamide and Anti-Bacterial Adhesive substance (ABA's) helps to clear blemishes. Biophytosebum provides a moisturizing effect, reducing dryness and skin tightness caused by conventional acne treatment.

Vitamin B3 (Activate Syrup) Oil-Free Cream: An oil-free formula enriched with mattifying agents. It helps to clear blemishes by promoting oil-free skin.

Vitamin B3 (Activate Syrup) UV High Protection Cream SPF 45: Protects acne-prone skin from daily sun-induced irritation and damage, keeping the skin hydrated and blemish-free at the same time. Non-sensitizing, non-comodogenic, fragrance-free and paraben-free.

Vitamin B3 (Activate Syrup) Gel: Provides intensive anti-blemish skin care for localized spots and promotes disappearance on the face or other small areas. It is non-sensitizing, fragrance-free and paraben-free.

Vitamin B3 (Activate Syrup) Moussant Soap Free Cleansing Gel: Helps clear blemishes by purifying and cleansing the skin gently.

The 4-methanol form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990).

Vitamin D3 (Activate Syrup) (Vitamin D2) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond. It differs from cholecalciferol in having a double bond between C22 and C23 and a methyl group at C24.

A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Vitamin E (Activate Syrup)&

Zinc (Activate Syrup) Capsule: Each capsule contains Zinc (Activate Syrup) sulphate monohydrate 54.93 mg, thiamine nitrate 10 mg, riboflavin 10 mg, pyridoxine hydrochloride 3 mg, Zinc (Activate Syrup) (coated) equivalent to cyanocobalamin 15 mcg, ascorbic acid 150 mg, folic acid 1 mg, nicotinamide 50 mg and calcium pantothenate 12.5 mg.

Zinc (Activate Syrup) Syrup: Each 5 mL contains Zinc (Activate Syrup) gluconate 34.9 mg, thiamine mononitrate 2.5 mg, riboflavin 2.5 mg, pyridoxine hydrochloride 1 mg, cyanocobalamin 3 mcg, ascorbic acid 50 mg, d-panthenol 12.5 mg and niacinamide 25 mg in a flavoured liquid glucose sorbitol syrup base.

Copper (Activate Syrup) 0.4 mg/mL (Cupric Chloride Injection, USP) is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN). Administration helps to maintain Copper (Activate Syrup) serum levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.

Supplemental L-Lysine (Activate Syrup) has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.

Potassium Iodide (Activate Syrup) is oral antithyroid agent. Potassium Iodide (Activate Syrup) is used as an adjunct to other antithyroid agents in the treatment of hyperthyroidism and thyrotoxicosis and preoperatively to induce thyroid involution. (radiation poisoning;)

Vitamin A (Activate Syrup) injection is effective for the treatment of Vitamin A (Activate Syrup) deficiency.

The parenteral administration is indicated when the oral administration is not feasible as in anorexia, nausea, vomiting, pre- and postoperative conditions, or it is not available as in the "Malabsorption Syndrome" with accompanying steatorrhea.

Pediatric Use: Vitamin A (Activate Syrup) treatment for deficiency states has been recognized as an especially effective and important therapy in the pediatric population.

Vitamin A (Activate Syrup) supplementation for deficiency states in this population has been addressed by the Committee on Clinical Practice Issues of the American Society for Clinical Nutrition, by the American Society for

Parenteral and Enteral Nutrition, and by the World Health Organization.

Vitamin B1 (Activate Syrup) deficiency

Pernicious anemia, both uncomplicated and accompanied by nervous system involvement.

Dietary deficiency of Vitamin B12 (Activate Syrup), occurring in strict vegetarians and in their breast-fed infants. (Isolated Vitamin B12 (Activate Syrup) deficiency is very rare).

Malabsorption of Vitamin B12 (Activate Syrup), resulting from structural or functional damage to the stomach, where intrinsic factor is secreted or to the ileum, where intrinsic factor facilitates Vitamin B12 (Activate Syrup) absorption. These conditions include tropical sprue, and nontropical sprue (idiopathic steatorrhea, gluten-induced enteropathy). Folate deficiency in these patients is usually more severe than Vitamin B12 (Activate Syrup) deficiency.

Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy). Total gastrectomy always produces Vitamin B12 (Activate Syrup) deficiency.

Structural lesions leading to Vitamin B12 (Activate Syrup) deficiency include regional ileitis, ileal resections, malignancies, etc.

Competition for Vitamin B12 (Activate Syrup) by intestinal parasites or bacteria.

The fish tapeworm (Diphyilobothrium latum) absorbs huge quantities of Vitamin B12 (Activate Syrup) and infested patients often have associated gastric atrophy. The blind-loop syndrome may produce deficiency of Vitamin B12 (Activate Syrup) or folate.

Inadequate utilization of Vitamin B12 (Activate Syrup). This may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia.

For the Schilling Test.

Vitamin B2 (Activate Syrup) deficiency

Helps clear blemishes. Vitamin B3 (Activate Syrup) Moussant Soap-Free Cleansing Gel Purifies & cleanses the skin. Vitamin B3 (Activate Syrup) Oil-Free Cream Promotes oil-free skin. Vitamin B3 (Activate Syrup) Isocorrexion Use for acne prone skin. Reduces skin dryness & tightness caused by conventional acne treatment. Vitamin B3 (Activate Syrup) Lotion For body acne in chest & back. Vitamin B3 (Activate Syrup) UV High Protection Cream SPF 45 For sun protection for acne prone skin. Vitamin B3 (Activate Syrup) Gel For localized spots.

Coenzyme A (metabolite of dexpanthenol) is important for deep penetrating moisturizer; stimulates epithelization; has wound healing effect; has an anti-inflammatory effect.

Only the D-Panthenol is the provitamin of D-Pantothenic acid (Vitamin B5 (Activate Syrup)), not the L-Panthenol.

A cream with dexpanthenol regularly applied to the skin improves the moisture content of dry skin significantly.

A cream with 5% dexpanthenol accelerates the healing of superficial wounds by approximately 30%.

An ointment with dexpanthenol prevents erythema due to UV light.

Dexpanthenol ointment also protects the lips against solar herpes, Sun burns, mild burns, skin irritations, dry or cracked skin, cosmetic or shaving rashes, post chemical peeling treatment, post laser resurfacing treatment ( 11th -15th day).

Dexpanthenol is effective for preventing / treating nappy dermatitis in infants.

* Sideroblastic anaemia

* Treatment and prophylaxis of Vitamin B6 (Activate Syrup) deficiency states

Vitamin D3 (Activate Syrup) has an important role in energize the intestinal absorption for calcium and phosphor, to regulate their metabolism and balance in blood. It helps bone calcification. Deficiency of Vitamin D3 (Activate Syrup) in the body causes deficiency of the calcium in the bone, weakness of its resistance and deformity.

Oral

Vitamin E (Activate Syrup) deficiency

Adult: 40-50 mg of d-α tocopherol daily.

Child: Neonate: 10 mg/kg once daily; 1 mth-18 yr: 2-10 mg/kg/day, up to 20 mg/kg.

Oral

Supplementation in cystic fibrosis

Adult: 100-200 mg daily of dl-α-tocoferil acetate or 67-135 mg daily of d-α-tocopherol.

Child: As α- tocopheryl acetate: 1 mth-1 yr 50 mg once daily; 1-12 yr 100 mg once daily; 12-18 yr 200 mg once daily. Dose to be adjusted as needed.

Oral

Abetalipoproteinaemia

Adult: 50-100 mg/kg daily of dl-α-tocoferil acetate or about 33-67 mg/kg daily of d-α-tocopherol.

Child: Neonate: 100 mg/kg once daily; 1 mth-18 yr: 50-100 mg/kg once daily.

Patients with deficiency of B-complex vitamins, vitamin C and Zinc (Activate Syrup) or where supplementation of these vitamins and Zinc (Activate Syrup) can be beneficial. Such patients and conditions include: Patients who are on prolonged antibiotic therapy; those who are suffering from infection, injuries, burns, fever, illness; patients with diarrhoea and GI disorders; patients who have undergone surgical operations; patients on diet restrictions eg, in diabetes, anorexia and alcoholism and in elderly persons; pregnant and lactating women due to increased nutritional needs.

Lysine (Activate Syrup) is an essential amino acid. Essential means that it is not produced by the body and therefore it must be taken in either by diet or by taking supplements. Lysine (Activate Syrup) is found in foods such as lentils, red meat, pork, poultry, cod fish, sardines, nuts, eggs, soy beans, brewer's yeast, and dairy products.

Lysine (Activate Syrup) has been used in alternative medicine as an aid to prevent cold sores around the mouth (caused by the herpes simplex virus). This product may make cold sores occur less often and may reduce the number of days a cold sore lasts. Lysine (Activate Syrup) is not a cure for herpes.

Other uses for Lysine (Activate Syrup) include treating metabolic acidosis, improving athletic performance, and helping the body absorb calcium supplements.

Not all uses for Lysine (Activate Syrup) have been approved by the FDA. Lysine (Activate Syrup) should not be used in place of medication prescribed for you by your doctor.

Lysine (Activate Syrup) is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Lysine (Activate Syrup) may also be used for purposes not listed in this product guide

Potassium Iodide (Activate Syrup) is the potassium salt form of iodide, a naturally occurring substance.

Potassium Iodide (Activate Syrup) can be used as an expectorant to thin mucus and loosen congestion in your chest and throat.

Potassium Iodide (Activate Syrup) is used in people with chronic breathing problems that can be complicated by thick mucus in the respiratory tract, such as asthma, chronic bronchitis, or emphysema.

Potassium Iodide (Activate Syrup) may also be used for purposes not listed in this medication guide.

Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are usually available in the foods that you eat. Vitamin A (Activate Syrup) is needed for night vision and for growth of skin, bones, and male and female reproductive organs. In pregnant women Vitamin A (Activate Syrup) is necessary for the growth of a healthy fetus.

Lack of Vitamin A (Activate Syrup) may lead to a rare condition called night blindness (problems seeing in the dark), as well as dry eyes, eye infections, skin problems, and slowed growth. Your health care professional may treat these problems by prescribing Vitamin A (Activate Syrup) for you.

Some conditions may increase your need for Vitamin A (Activate Syrup). These include:

• Diarrhea
• Eye diseases
• Intestine diseases
• Infections (continuing or chronic)
• Measles
• Pancreas disease
• Stomach removal
• Stress (continuing)

In addition, infants receiving unfortified formula may need Vitamin A (Activate Syrup) supplements.

Vitamin A (Activate Syrup) absorption will be decreased in any condition in which fat is poorly absorbed.

Increased need for Vitamin A (Activate Syrup) should be determined by your health care professional.

Claims that Vitamin A (Activate Syrup) is effective for treatment of conditions such as acne or lung diseases, or for treatment of eye problems, wounds, or dry or wrinkled skin not caused by lack of Vitamin A (Activate Syrup) have not been proven. Although Vitamin A (Activate Syrup) is being used to prevent certain types of cancer, some experts feel there is not enough information to show that this is effective, particularly in well-nourished individuals.

Injectable Vitamin A (Activate Syrup) is given by or under the supervision of a health care professional. Other forms of Vitamin A (Activate Syrup) are available without a prescription.

Thiamine is Vitamin B1 (Activate Syrup). Thiamine is found in foods such as cereals, whole grains, meat, nuts, beans, and peas. Thiamine is important in the breakdown of carbohydrates from foods into products needed by the body.

Thiamine is used to treat or prevent Vitamin B1 (Activate Syrup) deficiency. Thiamine injection is used to treat beriberi, a serious condition caused by prolonged lack of Vitamin B1 (Activate Syrup).

Thiamine taken by mouth (oral) is available without a prescription. Injectable thiamine must be given by a healthcare professional.

Thiamine may also be used for purposes not listed in this medication guide.

Cyanocobalamin is a man-made form of Vitamin B12 (Activate Syrup). Vitamin B12 (Activate Syrup) is important for growth, cell reproduction, blood formation, and protein and tissue synthesis.

Cyanocobalamin is used to treat Vitamin B12 (Activate Syrup) deficiency in people with pernicious anemia and other conditions.

Cyanocobalamin may also be used for purposes not listed in this medication guide.

Riboflavin is Vitamin B2 (Activate Syrup). Vitamins are naturally occurring substances necessary for many processes in the body. Riboflavin is important in the maintenance of many tissues of the body.

Riboflavin is used to prevent and to treat deficiencies of riboflavin.

Riboflavin may also be used for other purposes not listed in this medication guide.

Pyridoxine is Vitamin B6 (Activate Syrup). Vitamins occur naturally in foods such as meat, poultry, nuts, whole grains, bananas, and avocados. Vitamin B6 (Activate Syrup) is important for many processes in the body.

Pyridoxine is used to treat or prevent Vitamin B6 (Activate Syrup) deficiency. It is also used to treat a certain type of anemia (lack of red blood cells). Pyridoxine injection is also used to treat some types of seizure in babies.

Pyridoxine taken by mouth (oral) is available without a prescription. Injectable pyridoxine must be given by a healthcare professional.

Pyridoxine may also be used for purposes not listed in this medication guide.

Cholecalciferol is a Vitamin D3 (Activate Syrup). Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Cholecalciferol is used to treat or prevent many conditions caused by a lack of vitamin D, especially conditions of the skin or bones.

Cholecalciferol may also be used for purposes not listed in this medication guide.

Vitamin E (Activate Syrup) is an antioxidant that occurs naturally in foods such as nuts, seeds, and leafy green vegetables. Vitamin E (Activate Syrup) is a fat-soluble vitamin important for many processes in the body.

Vitamin E (Activate Syrup) is used to treat or prevent Vitamin E (Activate Syrup) deficiency. People with certain diseases may need extra Vitamin E (Activate Syrup).

Vitamin E (Activate Syrup) may also be used for purposes not listed in this medication guide.

Zinc (Activate Syrup) is a naturally occurring mineral. Zinc (Activate Syrup) is important for growth and for the development and health of body tissues.

Zinc (Activate Syrup) sulfate is used to treat and to prevent Zinc (Activate Syrup) deficiency.

Zinc (Activate Syrup) sulfate may also be used for purposes not listed in this medication guide.

Copper (Activate Syrup) 0.4 mg/mL (Cupric Chloride Injection, USP) contains 0.4 mg Copper (Activate Syrup)/mL and is administered intravenously only after dilution. The additive should be diluted in a volume of fluid not less than 100 mL. For the adult receiving TPN, the suggested additive dosage is 0.5 to 1.5 mg Copper (Activate Syrup)/day (1.25 to 3.75 mL/day). For pediatric patients, the suggested additive dosage is 20 mcg Copper (Activate Syrup)/kg/day (0.05 mL/kg/day). Infants weighing less than 1500 gm may have increased requirements because of their low body reserves and increased requirements for growth.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

Oral

Treatment and prophylaxis of herpes simplex

Adult: To treat symptoms: 3,000-9,000 mg/day in divided doses. To prevent recurrences: 500-1,500 mg/day.

Oral

Dietary supplementation

Adult: 500-1,000 mg/day.

Usual Adult Dose for Cough

300 to 650 mg orally 3 to 4 times a day.

Usual Adult Dose for Hyperthyroidism

Oral solution: 250 mg orally 3 times a day. Give for 10 to 14 days prior to thyroid surgery.

May be given as 0.25 mL of a 1 g/mL potassium iodine solution (SSKI) or as 4 mL of 325 mg/5 mL solution. Alternatively, 2 to 6 drops of a 10% Potassium Iodide (Activate Syrup)/5% iodine solution may be given orally 3 times a day with food.

Usual Adult Dose for Cutaneous Sporotrichosis

250 to 500 mg orally 3 times a day. Increase gradually to a maximum of 2 to 2.5 grams 3 times a day. Continue at maximum tolerated dose until the cutaneous lesions have resolved, usually 6 to 12 weeks.

Usual Adult Dose for Radiation Emergency

Pregnant or lactating women with exposure >= 5 centigrays (cGy): 130 mg orally per day.

>18 and <=40 years with exposure >= 10 centigrays (cGy): 130 mg orally per day.

>40 years with exposure >= 500 centigrays (cGy): 130 mg orally per day.

Usual Pediatric Dose for Cough

60 to 250 mg orally every 4 to 6 times a day. Maximum single dose 500 mg.

Usual Pediatric Dose for Hyperthyroidism

Oral solution: 250 mg orally 3 times a day. Give for 10 to 14 days prior to thyroid surgery.

Usual Pediatric Dose for Cutaneous Sporotrichosis

250 to 500 mg orally 3 times a day. Increase gradually to a maximum of 1.25 to 2 grams 3 times a day. Continue at maximum tolerated dose until the cutaneous lesions have resolved, usually 6 to 12 weeks.

Usual Pediatric Dose for Radiation Emergency

<=1 month with exposure >= 5 centigrays (cGy): 16 mg orally per day.

>1 month <=3 years with exposure >= 5 centigrays (cGy): 32 mg orally per day.

>3 years <= 18 years (less than 70 kg) with exposure >= 5 centigrays (cGy): 65 mg orally per day.

>13 years >= 70 kg with exposure >= 5 centigrays (cGy): 130 mg orally per day.

Renal Dose Adjustments

Potassium Iodide (Activate Syrup) should be used cautiously in patients with renal dysfunction. Due to impaired renal filtering of electrolytes, an increase in serum potassium can occur in patients with renal impairment.

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Other Comments

Administer after meals with food or milk or dilute with a large quantity of water, fruit juice, or broth.

Usual Adult Dose for Vitamin A (Activate Syrup) Deficiency

Initial dose: 100,000 Units intramuscularly once a day for 3 days

Maintenance dose: 50,000 Units intramuscularly once a day for 2 weeks

Use: Treatment of Vitamin A (Activate Syrup) deficiency when oral administration is not feasible or not available (e.g. anorexia, nausea, vomiting, pre- or post-operative conditions, "Malabsorption Syndrome" with accompanying steatorrhea)

Usual Adult Dose for Vitamin/Mineral Supplementation

US Recommended Dietary Allowance (RDA):

Adult male: 900 mcg retinol activity equivalents (RAE) (3000 international units [IU])

Tolerable Upper Intake Level (UL): 3000 mcg RAE (10,000 IU)

Adult female: 700 mcg RAE (2330 IU)

UL: 3000 mcg RAE (10,000 IU)

Comments:

-The Vitamin A (Activate Syrup) RDA is given as mcg of retinol activity equivalents (RAE) to account for the different bioactivities of retinol and provitamin A carotenoids.

-The body converts all dietary Vitamin A (Activate Syrup) into retinol; 2 mcg of beta-carotene from dietary supplements is converted to 1 mcg of retinol.

-The tolerable upper intake level is the maximum daily intake that is unlikely to have adverse health effects.

Usual Pediatric Dose for Vitamin A (Activate Syrup) Deficiency

Infants (under 1 year): 7500 to 15,000 Units intramuscularly once a day

Duration of therapy: 10 days

1 to 8 years: 17,500 to 35,000 Units intramuscularly once a day

Duration of therapy: 10 days

Adult dose:

Initial dose: 100,000 Units intramuscularly once a day for 3 days

Maintenance dose: 50,000 Units intramuscularly once a day for 2 weeks

Use: Treatment of Vitamin A (Activate Syrup) deficiency when oral administration is not feasible or not available (e.g. anorexia, nausea, vomiting, pre- or post-operative conditions, "Malabsorption Syndrome" with accompanying steatorrhea)

Usual Pediatric Dose for Vitamin/Mineral Supplementation

US Recommended Dietary Allowance (RDA):

0 to 6 months: 400 mcg retinol activity equivalents (RAE) (1332 international units [IU])

Tolerable Upper Intake Level (UL): 600 mcg RAE (2000 IU)

7 to 12 months: 500 mcg RAE (1665 IU)

UL: 600 mcg RAE (2000 IU)

1 to 3 years: 300 mcg RAE (1000 IU)

UL: 900 mcg RAE (3000 IU)

4 to 8 years: 400 mcg RAE (1332 IU)

UL: 900 mcg RAE (3000 IU)

9 to 13 years: 600 mcg RAE (2000 IU)

UL: 1700 mcg RAE (5667 IU)

14 to 18 years, male: 900 mcg RAE (3000 IU)

UL: 2800 mcg RAE (9333 IU)

14 to 18 years, female: 700 mcg RAE (2330 IU)

UL: 2800 mcg RAE (9333 IU)

Comments:

-The Vitamin A (Activate Syrup) RDA is given as mcg of retinol activity equivalents (RAE) to account for the different bioactivities of retinol and provitamin A carotenoids.

-The body converts all dietary Vitamin A (Activate Syrup) into retinol; 2 mcg of beta-carotene from dietary supplements is converted to 1 mcg of retinol.

-The tolerable upper intake level is the maximum daily intake that is unlikely to have adverse health effects.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

US Recommended Dietary Allowance (RDA):

Pregnancy:

14 to 18 years: 750 mcg retinol activity equivalents (RAE) (2500 international units [IU])

UL: 2800 mcg RAE (9333 IU)

18 to 50 years: 770 mcg RAE (2564 IU)

UL: 3000 mcg RAE (10,000 IU)

Lactation:

14 to 18 years: 1200 mcg RAE (2564 IU)

UL: 2800 mcg RAE (9333 IU)

18 to 50 years: 1300 mcg RAE (4329 IU)

UL: 3000 mcg RAE (10,000 IU)

Comments:

-The Vitamin A (Activate Syrup) RDA is given as mcg of retinol activity equivalents (RAE) to account for the different bioactivities of retinol and provitamin A carotenoids.

-The body converts all dietary Vitamin A (Activate Syrup) into retinol; 2 mcg of beta-carotene from dietary supplements is converted to 1 mcg of retinol.

-The tolerable upper intake level is the maximum daily intake that is unlikely to have adverse health effects.

Precautions

CONTRAINDICATIONS:

-Administration of the intramuscular formulation intravenously

-Hypervitaminosis A

-Hypersensitivity to any of the ingredients

-The safety of doses exceeding 6000 units Vitamin A (Activate Syrup) in pregnancy has not been established. Use of high doses in pregnancy or patients who may become pregnant is contraindicated. Doses above the recommended dietary allowance (RDA) may cause fetal harm; fetal abnormalities (central nervous system, eye, and palate malformations) were seen in animal overdose models. If patients become pregnant, apprise them of potential fetal harms.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Vitamin B12 (Activate Syrup) Atlantic Laboratories is used as injections SC, IV, IM, intralumbar, and also oral. With anemia associated with Vitamin B12 (Activate Syrup) deficiency is introduced on 100-200 mcg in 2 days. In anemia with symptoms of funicular myelosis and megalocytic anemia with diseases of the nervous system - 400-500 micrograms in the first 7 days daily, then 1 time every 5-7 days. In the period of remission in the absence of events funicular myelosis maintenance dose - 100 mcg 2 times a month, in the presence of neurological symptoms - at 200-400 mcg 2-4 times a month. In acute post-hemorrhagic anemia and iron anemia by 30-100 mcg 2-3 times a week. When aplastic anemia (especially in children) - 100 micrograms before clinical improvement. When nutritional anemia in infants and preterm - 30 mcg / day during 15 days.

In diseases of the central and peripheral nervous system and neurological diseases with a pain syndrome is administered in increasing doses - 200-500 mcg, with the improvement in the state - 100 mcg / day. The course of treatment with Vitamin B12 (Activate Syrup) Atlantic Laboratories is 2 weeks. In traumatic lesions of peripheral nervous system - at 200-400 mcg every other day for 40-45 days.

When hepatitis and cirrhosis - 30-60 mcg / day or 100 mg every other day for 25-40 days.

Dystrophy in young children, Down syndrome and cerebral palsy - by 15-30 mcg every other day.

When funicular myelosis, amyotrophic lateral sclerosis can be introduced into the spinal canal at 15-30 mcg, gradually increasing the dose of 200-250 micrograms.

In radiation sickness, diabetic neuropathy, sprue - by 60-100 mcg daily for 20-30 days.

When deficiency of Vitamin B12 (Activate Syrup) to prevent - IV or IM for 1 mg 1 time a month; for treatment - IV or IM for 1 mg daily for 1-2 weeks, the maintenance dose is 1-2 mg IV or IM from 1 per week, up to 1 per month. Duration of treatment is determined individually.

Vitamin B3 (Activate Syrup) Lotion: Apply to the areas being treated after cleansing twice a day, AM & PM.

Vitamin B3 (Activate Syrup) Isocorrexion & Vitamin B3 (Activate Syrup) Oil-Free Cream: Apply to the face and affected areas (neck, chest and back) after cleansing twice a day, AM & PM. Massage delicately to facilitate absorption.

Vitamin B3 (Activate Syrup) UV High Protection Cream SPF 45: Reapply every 2-3 hrs.

Vitamin B3 (Activate Syrup) Gel: Apply small amount of gel on affected areas by massaging gently in AM & PM.

Vitamin B3 (Activate Syrup) Moussant Soap Free Cleansing Gel: Apply in AM & PM to damp skin, face and affected areas (neck, chest and back) by massaging delicately. Rinse thoroughly and dry gently. May be used in shower.

1 tab daily.

Usual Adult Dose for Vitamin E (Activate Syrup) Deficiency

Treatment: 60 to 75 units orally once daily.

Prevention: 30 units orally once daily.

Usual Adult Dose for Tardive Dyskinesia

600 to 1600 units orally per day.

Usual Adult Dose for Sickle Cell Anemia

450 units orally per day.

Usual Adult Dose for Alzheimer's Disease

1000 units orally twice daily.

Usual Adult Dose for Dietary Supplement

Oral liquid formulation (Vitamin E (Activate Syrup)): 200 units (10 mL) orally once daily.

Usual Pediatric Dose for Vitamin E (Activate Syrup) Deficiency

1 unit/kg/day orally of water-miscible Vitamin E (Activate Syrup).

Usual Pediatric Dose for Retinopathy Prophylaxis

Prevention of retinopathy of prematurity or Bronchopulmonary dysplasia (BPD) secondary to oxygen therapy: 15 to 30 units/kg/day to maintain plasma levels between 1.5 to 2 mcg/mL (may need as high as 100 units/kg/day). Note: AAP considers this use investigational and routine use is not recommended.

Usual Pediatric Dose for Cystic Fibrosis

100 to 400 units/day orally.

Usual Pediatric Dose for Dietary Supplement

Dosing: 1 unit Vitamin E (Activate Syrup) = 1 mg dl-alpha-tocopherol acetate.

Oral:

Adequate Intake (AI):

1 to less than 6 months: 4 units daily

6 to less than 12 months: 5 units daily

Recommended Daily Allowance (RDA):

1 to 3 years: 6 units daily

4 to 8 years: 7 units daily

9 to 13 years: 11 units daily

13 years and Older: 15 units daily

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Although no longer available in the U.S., Vitamin E (Activate Syrup) injectable administered intravenously to premature infants may result in a potentially fatal syndrome consisting of thrombocytopenia, hepatomegaly, splenomegaly, ascites, and renal, hepatic, and pulmonary dysfunction.

Oral administration of large doses (200 mg per day) of a hyperosmolar Vitamin E (Activate Syrup) preparation to low-birthweight infants has been associated with the development of necrotizing enterocolitis.

Dialysis

Data not available

Other Comments

The oral liquid formulation (Vitamin E (Activate Syrup) [R]) is intended to enhance absorption in patients with conditions associated with malabsorption (e.g., Crohn's disease, ulcerative colitis ) or for patients who have difficulty swallowing capsules.

The oral liquid formulation (Vitamin E (Activate Syrup) [R]) may be taken directly or mixed with water or other beverage. It must be shaken well prior to each use and refrigerated after opening.

Zinc (Activate Syrup) 1 mg/mL (Zinc (Activate Syrup) Chloride Injection, USP) contains 1 mg Zinc (Activate Syrup)/mL and is administered intravenously only after dilution. The additive should be diluted prior to administration in a volume of fluid not less than 100 mL. For the metabolically stable adult receiving TPN, the suggested intravenous dosage is 2.5 to 4 mg Zinc (Activate Syrup)/day (2.5 to 4 mL/day). An additional 2 mg Zinc (Activate Syrup)/day (2 mL/day) is suggested for acute catabolic states. For the stable adult with fluid loss from the small bowel, an additional 12.2 mg Zinc (Activate Syrup)/liter of small bowel fluid lost (12.2 mL/liter of small bowel fluid lost), or an additional 17.1 mg Zinc (Activate Syrup)/kg of stool or ileostomy output (17.1 mL/kg of stool or ileostomy output) is recommended. Frequent monitoring of Zinc (Activate Syrup) blood levels is suggested for patients receiving more than the usual maintenance dosage level of Zinc (Activate Syrup).

For full term infants and children up to 5 years of age, 100 mcg Zinc (Activate Syrup)/kg/day

(0.1 mL/kg/day) is recommended. For premature infants (birth weight less than 1500 g) up to 3 kg in body weight, 300 mcg Zinc (Activate Syrup)/kg/day (0.3 mL/kg/day) is suggested.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS.

How supplied

Zinc (Activate Syrup) 1 mg/mL (Zinc (Activate Syrup) Chloride Injection, USP) is supplied in 10 mL Plastic Vials (List No. 4090).

Store at 20 to 25°C (68 to 77°F).

HOSPIRA, INC., LAKE FOREST, IL 60045 USA. Revised: October, 2004

Pregnancy or suspected malignant genital tumor of its existence, acute inflammation, subacute or chronic genital tract, congenital or acquired anatomic abnormalities of the uterus and cervix, endometriosis, malposition and malsituaciones accused the uterus, uterine hypoplasia, genital bleeding of unknown etiology blood clotting disorders, Wilson’s disease, allergy to Copper (Activate Syrup).

See also:
What is the most important information I should know about Lysine (Activate Syrup)?

L-Lysine (Activate Syrup) supplementation is contraindicated in those with the rare genetic disorder hyperlysinemia/hyperlysinuria.

See also:
What is the most important information I should know about Potassium Iodide (Activate Syrup)?

Hypersensitivity to iodide, iodine, or any component of the formulation; dermatitis herpetiformis; hypocomplementemic vasculitis, nodular thyroid condition with heart disease

See also:
What is the most important information I should know about Vitamin A (Activate Syrup)?

The intravenous administration. Hypervitaminosis A. Sensitivity to any of the ingredients in this preparation. Use in Pregnancy: Safety of amounts exceeding 6,000 Units of Vitamin A (Activate Syrup) daily during pregnancy has not been established at this time. The use of Vitamin A (Activate Syrup) in excess of the recommended dietary allowance may cause fetal harm when administered to a pregnant woman. Animal reproduction studies have shown fetal abnormalities associated with overdosage in several species. Malformations of the central nervous system, the eye, the palate, and the urogenital tract are recorded. Vitamin A (Activate Syrup) in excess of the recommended dietary allowance is contraindicated in women who are or may become pregnant. If Vitamin A (Activate Syrup) is used during pregnancy, or if the patient becomes pregnant while taking Vitamin A (Activate Syrup), the patient should be apprised of the potential hazard to the fetus.

See also:
What is the most important information I should know about Vitamin B1 (Activate Syrup)?

Contraindications for Vitamin B1 (Activate Syrup) (Vitamin B1 (Activate Syrup))

Hypersensitivity to Vitamin B1 (Activate Syrup) or any component of a product containing Vitamin B1 (Activate Syrup).

See also:
What is the most important information I should know about Vitamin B12 (Activate Syrup)?

Hypersensitivity to the components of the formula. History of allergy to the cobalamins (Vitamin B12 (Activate Syrup) and similar substances). Malignant tumors. By stimulating the growth of tissues, the Cobamamide could increase the high rate of cell multiplication. Sensitivity to cobalt. History of allergies to cobalamin (Vitamin B12 (Activate Syrup) and related substances).

- Malignant tumor: Due to the action of Vitamin B12 (Activate Syrup) on the growth of tissue cell multiplication rate high, the risk of exacerbation should be taken into account.

- Children under 6 years because of the dosage form

See also:
What is the most important information I should know about Vitamin B2 (Activate Syrup)?

None well documented.

Contraindications for Vitamin B3 (Activate Syrup) (Vitamin B3 (Activate Syrup))

Nicotinic acid is contraindicated in patients with a known hypersensitivity to any component of this medication; significant or unexplained hepatic dysfunction; active peptic ulcer disease; or arterial bleeding.

Haemophiliacs, patients with ileus (due to mechanical obstruction).

See also:
What is the most important information I should know about Vitamin B6 (Activate Syrup)?

Contraindications for Vitamin B6 (Activate Syrup) (Vitamin B6 (Activate Syrup))

Vitamin B6 (Activate Syrup) is contraindicated in those hypersensitive to any component of a Vitamin B6 (Activate Syrup)-containing product.

See also:
What is the most important information I should know about Vitamin D3 (Activate Syrup)?

Contraindications for vitamin D analogues (Vitamin D2, Vitamin D3 (Activate Syrup), Calcitriol, and Calcidiol)

Vitamin D should not be given to patients with hypercalcemia or evidence of vitamin D toxicity. Use of vitamin D in patients with known hypersensitivity to vitamin D (or drugs of the same class) or any of the inactive ingredients is contraindicated.

See also:
What is the most important information I should know about Vitamin E (Activate Syrup)?

Hypersensitivity to Vitamin E (Activate Syrup) or any component of the formulation

See also:
What is the most important information I should know about Zinc (Activate Syrup)?

Hypersensitivity to any of the ingredients of Zinc (Activate Syrup).

Use Potassium Iodide (Activate Syrup) solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Potassium Iodide (Activate Syrup) solution. Talk to your pharmacist if you have questions about this information.
• Take Potassium Iodide (Activate Syrup) solution by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Use the dropper that comes with Potassium Iodide (Activate Syrup) solution to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you are instructed to take more than 1 dose of Potassium Iodide (Activate Syrup) solution, do NOT take it sooner than 24 hours after the last dose of Potassium Iodide (Activate Syrup) solution. Do NOT take more than 1 dose per day.
• If you miss a dose of Potassium Iodide (Activate Syrup) solution, take it as soon as possible. If you are instructed to take more than 1 dose of Potassium Iodide (Activate Syrup) solution and it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.

Ask your health care provider any questions you may have about how to use Potassium Iodide (Activate Syrup) solution.

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Pyridoxine tablets are taken by mouth. Injectable pyridoxine is injected into a muscle or into a vein through an IV. You may be shown how to use injections at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

The recommended dietary allowance of pyridoxine increases with age. Follow your healthcare provider's instructions. You may also consult the Office of Dietary Supplements of the National Institutes of Health, or the U.S. Department of Agriculture (USDA) Nutrient Database (formerly "Recommended Daily Allowances") listings for more information.

Pyridoxine is only part of a complete program of treatment that may also include a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you should eat or avoid to help control your condition.

Store at room temperature away from moisture and heat.

Use: Labeled Indications

Trace element added to parenteral nutrition (PN) to prevent Copper (Activate Syrup) deficiency; orally as a dietary supplement

Herpes simplex infections.

Potassium Iodide (Activate Syrup) is used to loosen and break up mucus in the airways. This helps you cough up the mucus so you can breathe more easily if you have long-term lung problems (e.g., asthma, chronic bronchitis, emphysema). This medication is known as an expectorant.

Potassium Iodide (Activate Syrup) is also used along with antithyroid medicines to prepare the thyroid gland for surgical removal, to treat certain overactive thyroid conditions (hyperthyroidism), and to protect the thyroid in a radiation exposure emergency. It works by shrinking the size of the thyroid gland and decreasing the amount of thyroid hormones produced.

In a radiation emergency, Potassium Iodide (Activate Syrup) blocks only the thyroid from absorbing radioactive iodine, protecting it from damage and reducing the risk of thyroid cancer. Use this medication along with other emergency measures that will be recommended to you by public health and safety officials (e.g., finding safe shelter, evacuation, controlling food supply).

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This drug may also be used to treat a certain type of fungal skin infection (sporotrichosis).

How to use Potassium Iodide (Activate Syrup)

Take this medication by mouth with a full glass of water (8 ounces or 240 milliliters) as directed by your doctor or public health and safety officials. To avoid stomach upset, take after meals or with food. Drink plenty of liquids with this medication unless otherwise directed. If you are taking the tablets, do not lie down for 10 minutes after taking this medication. If you are using the drops or liquid medication, use the dropper that comes with the bottle or a medication spoon/device to measure the correct dose. Liquid forms of this product may be mixed in water, milk, formula, or juice before taking. Do not use this medication if the solution turns brownish-yellow.

Dosage is based on your medical condition and response to therapy. In children, dosage is also based on age. Do not increase your dose, take it more often, or take it for longer than prescribed or recommended because of the increased risk of side effects.

In a radiation emergency, take this drug only when public health and safety officials tell you to do so. Read the Patient Information Leaflet that comes with the medication. Start treatment as soon as possible for the best protection. Take this medication usually once every 24 hours. The length of treatment will be determined by public health and safety officials and depends on several factors (e.g., whether you continue to be exposed to the radiation, and whether you are pregnant, breast-feeding, or have a newborn baby). See also Precautions.

If so directed, use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Inform your doctor if your condition persists or worsens.

Vitamin A (Activate Syrup) is used to prevent or treat low levels of the vitamin in people who do not get enough of it from their diets. Most people who eat a normal diet do not need extra Vitamin A (Activate Syrup). However, some conditions (such as protein deficiency, diabetes, hyperthyroidism, liver/pancreas problems) can cause low levels of Vitamin A (Activate Syrup). Vitamin A (Activate Syrup) plays an important role in the body. It is needed for growth and bone development and to maintain the health of the skin and eyesight. Low levels of Vitamin A (Activate Syrup) may cause vision problems (such as night blindness) and permanent eye damage.

How to use Vitamin A (Activate Syrup)

Take this vitamin by mouth with or without food, usually once daily. Follow all directions on the product package, or take as directed by your doctor. If you are uncertain about any of the information, consult your doctor or pharmacist.

If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

Dosage is based on your age, medical condition, and response to treatment.

Use this vitamin regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not increase your dose or use this vitamin more often than recommended. Your condition will not improve any faster, and your risk of side effects will increase.

Tell your doctor if your condition persists or worsens. If you think you may have a serious medical problem, seek immediate medical attention.

Vitamin B2 (Activate Syrup) (riboflavin) supplementation is used to prevent and treat riboflavin deficiency. Vitamin B2 (Activate Syrup) may prevent migraine headaches at high doses and be useful for prevention of eye conditions such as cataract, glaucoma and tired eyes (fatigue). Vitamin B2 (Activate Syrup) is also used for boosting of immune system, and maintenance of healthy hair, skin, nails and mucous membranes.

Hypercholesterolaemia, hyperlipidemia, hypertriglyceridaemia, pellagra.

It is used for the treatment and prevention of Vitamin B6 (Activate Syrup) deficiency. It is important for the breakdown of protein, fats, and carbohydrates from foods.

Vitamin D3 (Activate Syrup) is used for the prevention and treatment of vitamin D deficiency. Vitamin D3 (Activate Syrup) is important for absorption of calcium in the body. It is also used to prevent bone disorders such as osteomalacia and rickets.

This supplement is used to prevent or treat a lack of Vitamin E (Activate Syrup) in the body. A low body level of Vitamin E (Activate Syrup) is rare. Most people who eat a normal diet do not need extra Vitamin E (Activate Syrup). However, Vitamin E (Activate Syrup) supplements are used in premature newborns and in people who have problems absorbing enough Vitamin E (Activate Syrup) from their diets. Vitamin E (Activate Syrup) is important in protecting your body's cells from damage. It is known as an antioxidant.

How to use Vitamin E (Activate Syrup)

Take this product by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

If you are using a liquid form of this product, carefully measure your dose using a medication-measuring device or spoon. Do not use a household spoon because you may not get the correct dose. If your liquid form is a suspension, shake the bottle well before each dose.

Dosage is based on your medical condition and response to treatment. Do not increase your dose or take it more often than recommended. Taking too much Vitamin E (Activate Syrup) may increase your risk of side effects.

High doses of Vitamin E (Activate Syrup) (400 units or more per day) may increase the chance of rare but very serious side effects. There is no proof that high doses of Vitamin E (Activate Syrup) help to prevent or treat heart disease. There is very little evidence that it helps prevent or treat Alzheimer's disease. In some people, taking these high doses may even be harmful. Talk to your doctor or pharmacist and discuss the risks and benefits before taking Vitamin E (Activate Syrup) supplements.

If your doctor prescribes this product for Vitamin E (Activate Syrup) deficiency, use it regularly to get the most benefit from it. To help you remember, take it at the same time each day. You should see improvement of symptoms such as numbness/tingling of the hands/feet and weakness. If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.

Ascorbic Acid: Copper (Activate Syrup) may decrease the serum concentration of Ascorbic Acid. Management: To minimize the risk for ascorbic acid degradation, add multivitamin product to TPN solution immediately prior to infusion or administer multivitamin and Copper (Activate Syrup) in separate containers. Consider therapy modification

See also:
What other drugs will affect Lysine (Activate Syrup)?

Since Lysine (Activate Syrup) does not alter clonixinate coagulation, no interaction with anticoagulant drugs and do not require dose adjustments. Concomitant use of anticholinergic drugs to be avoided by the possibility that they enhance their effects atropine.

See also:
What other drugs will affect Potassium Iodide (Activate Syrup)?

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: ACE inhibitors (e.g., captopril, lisinopril), angiotensin receptor blockers (ARBs such as losartan, valsartan), certain "water pills" (potassium-sparing diuretics such as amiloride, spironolactone, triamterene), drospirenone, eplerenone, lithium, potassium-containing drugs (e.g., supplements such as potassium chloride).

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

See also:
What other drugs will affect Vitamin A (Activate Syrup)?

The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.

Some products that may interact with this vitamin include: acitretin, alitretinoin, bexarotene, cholestyramine, isotretinoin, tretinoin, other products that contain Vitamin A (Activate Syrup) (such as multivitamins), warfarin.

Avoid taking Vitamin A (Activate Syrup) at the same time as you take neomycin, orlistat, and mineral oil. If you take any of these medications, separate your doses from your dose of Vitamin A (Activate Syrup) by at least 2 hours.

This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.

See also:
What other drugs will affect Vitamin B1 (Activate Syrup)?

Interactions for Vitamin B1 (Activate Syrup) (Vitamin B1 (Activate Syrup))

Loop Diuretics,

Oral Contraceptives, Stavudine, Tricyclic Antidepressants

See also:
What other drugs will affect Vitamin B12 (Activate Syrup)?

In an application of Vitamin B12 (Activate Syrup) Atlantic Laboratories with hormonal contraceptives for oral administration may decrease the concentration of cyanocobalamin in plasma.

In an application with anticonvulsant drugs decreased cyanocobalamin absorption from the gut.

In an Vitamin B12 (Activate Syrup) Atlantic Laboratories application with neomycin, aminosalicylic acid, colchicine, cimetidine, ranitidine, drugs potassium decreased cyanocobalamin absorption from the gut.

Cyanocobalamin may exacerbate allergic reactions caused by thiamine.

When parenteral application of chloramphenicol may decrease the hematopoietic effects of cyanocobalamin with anemia.

See also:
What other drugs will affect Vitamin B2 (Activate Syrup)?

Interactions for Vitamin B2 (Activate Syrup) (Vitamin B2 (Activate Syrup))

Alcohol - impairs the intestinal absorption of riboflavi

Antidepressants (tricyclics or phenothiazines) - requirements for riboflavin may be increased in patients receiving these medications

Probenecid - concurrent use decreases gastrointestinal absorption of riboflavin; requirements for riboflavin may be increased in patients receiving probenecid.

Interactions for Vitamin B3 (Activate Syrup) (Vitamin B3 (Activate Syrup))

Antihypertensive Therapy: Nicotinic acid may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension

Aspirin: Concomitant aspirin may decrease the metabolic clearance of nicotinic acid. The clinical relevance of this finding is unclear

Other: Concomitant alcohol or hot drinks may increase the side effects of flushing and pruritus and should be avoided at the time of drug ingestion.

Dextropanthenyl alcohol in combination with hydrocortisone may be more effective than topical hydrocortisone alone in some dermatoses.

See also:
What other drugs will affect Vitamin B6 (Activate Syrup)?

Interactions for Vitamin B6 (Activate Syrup) (Vitamin B6 (Activate Syrup))

Amiodarone: Concomitant use of Vitamin B6 (Activate Syrup) and amiodarone may enhance amiodarone-induced photosensitivity reactions. Doses of Vitamin B6 (Activate Syrup) greater than 5-10 milligrams/day should be avoided by those taking amiodarone Carbamazepine: Chronic use of carbamazepine may result in a significant decrease in plasma pyridoxal 5-phosphate levels Cycloserine: Cycloserine may react with pyridoxal 5-phosphate to form a metabolically inactive oxime, which may result in a functional Vitamin B6 (Activate Syrup) deficiency Ethionamide: The use of ethionamide may increase Vitamin B6 (Activate Syrup) requirements Fosphenytoin: High doses of Vitamin B6 (Activate Syrup) may lower plasma levels of phenytoin. Fosphenytoin is a prodrug of phenytoin Hydralazine: The use of hydralazine may increase Vitamin B6 (Activate Syrup) requirements Isoniazid: (isonicotinic acid, INH). Isoniazid reacts with pyridoxal 5-phosphate to form a metabolically inactive hydrazone, which may result in functional Vitamin B6 (Activate Syrup) deficiency Levodopa: Concomitant use of levodopa and Vitamin B6 (Activate Syrup) in doses of 5 milligrams or more daily may reverse the therapeutic effects of levodopa. Vitamin B6 (Activate Syrup) does not reverse the therapeutic effects of levodopa if levodopa is taken concurrently with the levodopa decarboxylase inhibitor carbidopa. Levodopa is typically administered as a combination product with carbidopa

Oral contraceptives: The use of oral contraceptives may increase Vitamin B6 (Activate Syrup) requirements. This was more the case with the older oral contraceptive agents with high-dose estrogen/progestin. It appears to be less the case with the newer low-dose estrogen/progestin products Penicillamine: Penicillamine may react with pyridoxal 5-phosphate to form a metabolically inactive thiazolidine, which may result in a functional Vitamin B6 (Activate Syrup) deficiency Phenelzine: Phenelzine may react with pyridoxal 5-phosphate to yield a metabolically inactive hydrazone compound Phenobarbital: High doses of Vitamin B6 (Activate Syrup) may lower plasma levels of phenobarbital Phenytoin: High doses of Vitamin B6 (Activate Syrup) may lower plasma levels of phenytoin Theophylline: Theophylline may react with pyridoxal 5-phosphate leading to low plasma levels of the coenzyme. This may increase the risk of theophylline-induced seizures Valproic acid: Chronic use of valproic acid may result in a significant decrease in plasma pyridoxal 5-phosphate levels.

See also:
What other drugs will affect Vitamin D3 (Activate Syrup)?

Interactions for vitamin D analogues (Vitamin D2, Vitamin D3 (Activate Syrup), Calcitriol, and Calcidiol)

Cholestyramine

Cholestyramine has been reported to reduce intestinal absorption of fat soluble vitamins; as such it may impair intestinal absorption of any of vitamin D

Phenytoin/Phenobarbital

The coadministration of phenytoin or phenobarbital will not affect plasma concentrations of vitamin D, but may reduce endogenous plasma levels of calcitriol/ergocalcitriol by accelerating metabolism. Since blood level of calcitriol/ergocalcitriol will be reduced, higher doses of Rocaltrol may be necessary if these drugs are administered simultaneously

Thiazides

Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. Some reports have shown that the concomitant administration of thiazides with vitamin D causes hypercalcemia. Therefore, precaution should be taken when coadministration is necessary

Digitalis

Vitamin D dosage must be determined with care in patients undergoing treatment with digitalis, as hypercalcemia in such patients may precipitate cardiac arrhythmias

Ketoconazole

Ketoconazole may inhibit both synthetic and catabolic enzymes of vitamin D. Reductions in serum endogenous vitamin D concentrations have been observed following the administration of 300 mg/day to 1200 mg/day ketoconazole for a week to healthy men. However, in vivo drug interaction studies of ketoconazole with vitamin D have not been investigated

Corticosteroids

A relationship of functional antagonism exists between vitamin D analogues, which promote calcium absorption, and corticosteroids, which inhibit calcium absorption

Phosphate-Binding Agents

Since vitamin D also has an effect on phosphate transport in the intestine, kidneys and bones, the dosage of phosphate-binding agents must be adjusted in accordance with the serum phosphate concentration

Vitamin D

The coadministration of any of the vitamin D analogues should be avoided as this could create possible additive effects and hypercalcemia

Calcium Supplements

Uncontrolled intake of additional calcium-containing preparations should be avoided

Magnesium

Magnesium-containing preparations (eg, antacids) may cause hypermagnesemia and should therefore not be taken during therapy with vitamin D by patients on chronic renal dialysis.

See also:
What other drugs will affect Vitamin E (Activate Syrup)?

Agents with Antiplatelet Properties (e.g., P2Y12 inhibitors, NSAIDs, SSRIs, etc.): Vitamin E (Activate Syrup) (Systemic) may enhance the antiplatelet effect of Agents with Antiplatelet Properties. Monitor therapy

Anticoagulants: Vitamin E (Activate Syrup) (Systemic) may enhance the anticoagulant effect of Anticoagulants. Monitor therapy

CycloSPORINE (Systemic): Vitamin E (Activate Syrup) (Systemic) may decrease the serum concentration of CycloSPORINE (Systemic). Monitor therapy

Ibrutinib: Vitamin E (Activate Syrup) (Systemic) may enhance the antiplatelet effect of Ibrutinib. Monitor therapy

Orlistat: May decrease the serum concentration of Vitamins (Fat Soluble). Management: Administer oral fat soluble vitamins at least 2 hours before or after the administration of orlistat. Similar precautions do not apply to parenterally administered fat soluble vitamins. Consider therapy modification

Tipranavir: May enhance the adverse/toxic effect of Vitamin E (Activate Syrup) (Systemic). Management: Patients taking tipranavir oral solution are advised to avoid taking additional Vitamin E (Activate Syrup), beyond the amounts contained in a multivitamin product. This interaction does not apply to tipranavir capsules. Consider therapy modification

See also:
What other drugs will affect Zinc (Activate Syrup)?

Pyridoxine reduces the effects of levodopa (but this does not occur if a dopa decarboxylase is also given); decreases serum concentrations of phenobarbitone. Concurrent administration of drugs eg, isoniazid, penicillamine and oral contraceptives increase the requirement for pyridoxine.

Absorption of cyanocobalamin from the GIT may be reduced by neomycin, aminosalicylic acid, histamine H₂-receptor antagonists and colchicine. Serum concentrations may be decreased by concurrent administration of oral contraceptives. Many of these interactions are unlikely to be of clinical significance but should be taken into account when performing assays for blood concentrations.

Parenteral chloramphenicol may attenuate the effect of Zinc (Activate Syrup) in anaemia.

Folate deficiency states may be produced by a number of drugs including antiepileptics, oral contraceptives, antituberculous drugs, alcohol and folic acid antagonists eg, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides; folic acid may decrease serum-phenytoin concentrations.

There may be an increased risk of myopathy or rhabdomyolysis when nicotinic acid is used concurrently with statins. Nicotinamide may increase the requirements for insulin or oral hypoglycaemics.

Ascorbic acid may increase the absorption of iron-deficiency states.

Ascorbic acid is often given in addition to desferrioxamine to patients with iron overload (thalassemia) to achieve better iron excretion. However, early on in treatment when there is excess tissue iron, there is some evidence that ascorbic acid may worsen the iron toxicity, particularly to the heart. Thus, ascorbic acid should not be given for the first month after starting desferrioxamine treatment.

The absorption of Zinc (Activate Syrup) may be reduced by iron supplements, penicillamine, phosphorus-containing preparations and tetracyclines. Zinc (Activate Syrup) supplements reduce the absorption of Zinc (Activate Syrup), ciprofloxacin, iron, norfloxacin, penicillamine and tetracyclines.

Adverse Reactions

Generally well tolerated; excessive Copper (Activate Syrup) levels may result in the following adverse effect.

Hepatic: Hepatic insufficiency (including hepatic necrosis)

See also:
What are the possible side effects of Lysine (Activate Syrup)?

Adverse effects associated with the mechanics of retrograde genitourinary procedures include injury to the urethra, bladder, and ureter, and introduction of infection. {03} {06} {31}

Systemic adverse effects, similar to those that occur with direct intravascular injection of the diatrizoate salts, may also occur with intravesical or intraureteral instillation as a result of inadvertent intravascular entry of the contrast solution due to either bladder absorption or pyelorenal backflow. {06} {31}

Systemic adverse effects, although rare, are possible with intrauterine instillation if medium is absorbed systemically after being retained in the uterine cavity or spilled into the peritoneal cavity. {06} {34}

The following side/adverse effects have been selected on the basis of their potential clinical significance (possible signs and symptoms in parentheses where appropriate)—not necessarily inclusive

See also:
What are the possible side effects of Potassium Iodide (Activate Syrup)?

Applies to Potassium Iodide (Activate Syrup): oral solution, oral syrup

In addition to its needed effects, some unwanted effects may be caused by Potassium Iodide (Activate Syrup) (the active ingredient contained in Potassium Iodide (Activate Syrup)). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Potassium Iodide (Activate Syrup), check with your doctor or nurse as soon as possible:

Less common:

• Hives
• joint pain
• swelling of arms, face, legs, lips, tongue, and/or throat
• swelling of lymph glands

• Burning of mouth or throat
• confusion
• headache (severe)
• increased watering of mouth
• irregular heartbeat
• metallic taste
• numbness, tingling, pain or weakness in hands or feet
• soreness of teeth and gums
• sores on skin
• symptoms of head cold
• unusual tiredness
• weakness or heaviness of legs

Minor Side Effects

Some of the side effects that can occur with Potassium Iodide (Activate Syrup) may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:

• Diarrhea
• nausea or vomiting
• stomach pain

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What are the possible side effects of Vitamin A (Activate Syrup)?

This vitamin usually has no side effects when used in recommended doses. If you have any unusual effects, contact your doctor or pharmacist promptly.

A very serious allergic reaction to this vitamin is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

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What are the possible side effects of Vitamin B1 (Activate Syrup)?

Applies to thiamine: capsule, solution, tablet, tablet enteric coated

As well as its needed effects, thiamine (the active ingredient contained in Vitamin B1 (Activate Syrup)) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking thiamine, check with your doctor immediately:

Rare - Soon after receiving injection only

• Coughing
• difficulty in swallowing
• hives
• itching of skin
• swelling of face, lips, or eyelids
• wheezing or difficulty in breathing

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What are the possible side effects of Vitamin B12 (Activate Syrup)?

Applies to cyanocobalamin: intramuscular solution

Other dosage forms:

• nasal gel/jelly, nasal spray

As well as its needed effects, cyanocobalamin (the active ingredient contained in Vitamin B12 (Activate Syrup)) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking cyanocobalamin, check with your doctor or nurse immediately:

Incidence not known:

• Abdominal or stomach pain
• bleeding from the gums or nose
• blue lips and fingernails
• chest pain
• cough
• coughing that sometimes produces a pink frothy sputum
• decreased urine output
• difficult, fast, noisy breathing, sometimes with wheezing
• difficulty with swallowing
• dilated neck veins
• dizziness
• extreme fatigue
• eye pain
• fast heartbeat
• headache
• hives, itching, or skin rash
• increased sweating
• irregular breathing
• irregular heartbeat
• pale skin
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• ringing in the ears
• swelling of the face, fingers, feet, or lower legs
• tightness in the chest
• unusual tiredness or weakness
• weight gain

Minor Side Effects

Some cyanocobalamin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Incidence not known:

• Diarrhea
• skin rash with a general disease

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What are the possible side effects of Vitamin B2 (Activate Syrup)?

Genitourinary

Yellow-orange discoloration of urine.

Allergic sensitization has been reported rarely following oral and parenteral administration of Folic Acid.

At recommended doses, nicotinamide is expected to be well tolerated. Gastrointestinal distress such as nausea or vomiting have been associated with the administration of nicotinamide or zinc at doses greater than the recommended dose of nicotinamide

Nicotinamide: Dizziness, headache, hyperglycemia, nausea, vomiting, diarrhea, elevations in liver function tests, hepatotoxicity, blurred vision, flushing, rash.

No serious side effects have been reported, even at intakes of up to 10,000 mg (10 grams) per day. Very large amounts of pantothenic acid (several grams per day) can cause diarrhea.

Pantothenic acid works together with Vitamin B5 (Activate Syrup), Vitamin B5 (Activate Syrup), and Vitamin B5 (Activate Syrup) to help make the fuel our bodies run on—ATP.

There is one report of a 76-year-old woman who developed a life-threatening condition (eosinophilic pleuropericardial effusion) while taking 300 mg of pantothenic acid per day and 10 mg of biotin per day.2 However, it is not clear whether the vitamins caused the problem.

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What are the possible side effects of Vitamin B6 (Activate Syrup)?

Applies to pyridoxine: capsule, injectable, solution, tablet, tablet enteric coated, tablet extended release

As well as its needed effects, pyridoxine (the active ingredient contained in Vitamin B6 (Activate Syrup)) may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking pyridoxine, check with your doctor or nurse as soon as possible:

With large doses

• Clumsiness
• numbness of hands or feet

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What are the possible side effects of Vitamin D3 (Activate Syrup)?

Applies to cholecalciferol: oral capsule, oral capsule liquid filled, oral solution, oral tablet, oral tablet chewable, oral wafer

As well as its needed effects, cholecalciferol (the active ingredient contained in Vitamin D3 (Activate Syrup)) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking cholecalciferol, check with your doctor immediately:

Incidence not known:

• Cough
• difficulty swallowing
• dizziness
• fast heartbeat
• hives or itching
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• skin rash
• tightness in the chest
• unusual tiredness or weakness

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What are the possible side effects of Vitamin E (Activate Syrup)?

Applies to Vitamin E (Activate Syrup): oral capsule, oral capsule liquid filled, oral liquid, oral powder for solution, oral solution, oral tablet, oral tablet chewable

In addition to its needed effects, some unwanted effects may be caused by Vitamin E (Activate Syrup) (the active ingredient contained in Centrum Singles-Vitamin E (Activate Syrup)). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Vitamin E (Activate Syrup), check with your doctor or nurse as soon as possible:

With doses greater than 400 Units a day and long-term use

• Blurred vision
• diarrhea
• dizziness
• headache
• nausea or stomach cramps
• unusual tiredness or weakness

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What are the possible side effects of Zinc (Activate Syrup)?

Applies to Zinc (Activate Syrup) sulfate: capsules, tablets

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur while taking Zinc (Activate Syrup) sulfate (the active ingredient contained in Zinc (Activate Syrup))

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe vomiting; unusual restlessness; very dry mouth, eyes, or skin.