Chlorhexidine Gluconate
Method of action:
Antiseptics And Disinfectants, Disinfectant, Stomatological Preparations, Throat Preparations
Available in countries
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Medically reviewed by Kovalenko Svetlana Olegovna, PharmD. Last updated on 2019.10.20

Special warnings and precautions for use

Acriflex contains chlorhexidine. Chlorhexidine is known to induce hypersensitivity, including generalised allergic reactions and anaphylactic shock. The prevalence of chlorhexidine hypersensitivity is not known, but available literature suggests this is likely to be very rare. Acriflex should not be administered to anyone with a potential history of an allergic reaction to a chlorhexidine-containing compound.

Keep away from the eyes.

Avoid contact with the brain, meninges and middle ear. Not for use in body cavities.

Effects on ability to drive and use machines

None known.

Undesirable effects

Skin disorders

Frequency not known: Allergic skin reactions such as dermatitis, pruritus, erythema, eczema, rash, urticaria, skin irritation, and blisters.

Immune disorders

Frequency not known: Hypersensitivity including anaphylactic shock.

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Care Scheme at: www.mhra.gov.uk/yellowcard.


Overdosage is extremely unlikely. Chlorhexidine is poorly absorbed and systemic effects are unlikely even if large amounts are swallowed. However, gastric lavage followed by supportive measures may be used as appropriate.

Pharmacodynamic properties

Chlorhexidine is a bisbiguanide disinfectant which is effective against a wide range of vegetative gram-positive and gram-negative bacteria.

Pharmacokinetic properties

Not applicable.

Preclinical safety data

Not applicable.

List of excipients

Arlatone 983 S

Cetostearyl Alcohol

Liquid Paraffin

Dimeticone 20

Glycerol (E422)

Quinoline Yellow Lake (E104)

Purified Water


None known.

Shelf life

Three years unopened.

Special precautions for storage

None stated.

Nature and contents of container

Internally lacquered aluminium, blind end tubes containing 30gm of product, closed with a polyolefin cap in a cardboard outer.

Special precautions for disposal and other handling

For general use, apply freely and smooth gently into the skin. For cuts, abrasions, burns, etc. spread freely and, if necessary, cover with a dressing.

There are no recommended dosage schedules as the product is for use as needed.

Marketing authorisation holder

Thornton & Ross Limited



West Yorkshire


United Kingdom

Marketing authorisation number(s)

PL 00240/0116

Date of first authorisation/renewal of the authorisation


Date of revision of the text


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