ACC Kid

Quick links to important sections

Medically reviewed

Laura Arias

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of ACC Kid

Quick Facts Table

Property Description
Active ingredient Acetylcysteine (N-acetyl-L-cysteine)
Form Oral solid preparation (Effervescent tablet or powder)
Pharmacological class Mucolytic agent, Secretolytic agent
Common use General support for clearing thick respiratory secretions
Origin Synthetic amino acid derivative

What Type of Medicine is ACC Kid? (Classification and Origin)

ACC Kid is a specialized pharmaceutical preparation designed for the pediatric population, classified under the high-level pharmacological class of mucolytic and secretolytic agents. Its identity is based on the single active substance, Acetylcysteine (INN), which is a synthetic derivative of the amino acid L-cysteine. This classification as a mucolytic highlights its distinct role in directly affecting the chemical properties of respiratory secretions, distinguishing it from simple expectorants.

Composition and Preparation Form

The composition of this preparation features Acetylcysteine as the sole active ingredient, confirming it as a monopreparation. ACC Kid is delivered in an oral solid dosage form, typically as an effervescent tablet or a powder intended for dissolution into an oral solution prior to ingestion. This method is utilized for oral administration, with the dry components containing excipients that aid in the dissolution process and stability of the product.

What is the General Purpose of Acetylcysteine? (Core Benefit)

The general purpose of this medicine is to address and alleviate difficulties associated with overly thick or viscous secretions in the respiratory passages, as it works by thinning the mucus in the airways. By operating as a powerful secretolytic agent, Acetylcysteine chemically reduces the stickiness and overall viscosity of the mucus. This fundamental action supports the natural physiological process of bronchial secretion clearance, a benefit that is clinically recognized for assisting the expulsion of tenacious respiratory fluids.

Regulatory References

  1. MedlinePlus Drug Information on Acetylcysteine

What side effects are possible with ACC Kid?

Possible side effects and safety information

The officially documented safety profile of Acetylcysteine (the active ingredient in ACC Kid) categorizes potential reactions by frequency and the body system affected. These classifications are based strictly on regulatory review from authorities such as the EMA and FDA, and define the scope of expected safety characteristics.


Frequency-Classified Adverse Reactions

Adverse reactions are formally grouped according to their documented occurrence rates in clinical use:

  • Uncommon (Affecting 1 to 10 users in 1,000): Headache, tinnitus (ringing in the ears), pyrexia (fever), tachycardia (increased heart rate), and hypersensitivity reactions.
  • Rare (Affecting 1 to 10 users in 10,000): Dyspepsia (indigestion) and stomatitis.

Commonly reported non-serious effects documented in the official labels include nausea and vomiting.


System-Organ-Class Grouping and Serious Events

The regulatory documentation groups potential effects across several systems, including Gastrointestinal Disorders (e.g., nausea, vomiting), Nervous System Disorders (e.g., headache), and Immune System Disorders (hypersensitivity).

Serious Adverse Reactions

Although very rare, the official profile notes the potential for severe reactions, including Severe Cutaneous Adverse Reactions (SCARs), such as Stevens-Johnson syndrome and Toxic Epidermal Necrolysis, as well as Anaphylactic Shock. There are also very rare reports of Haemorrhage associated with administration.


Population-Specific Safety Notes

Specific attention is drawn to patients with hyperreactive bronchial systems due to the potential for bronchospasm upon oral administration. The possibility of SCARs is explicitly documented as occurring mostly during the initial phase of treatment. The medicine is formally contraindicated in individuals with known hypersensitivity to the active substance or any of its excipients.

Overdose and Emergency Response

The official regulatory documentation for Acetylcysteine (the active ingredient in ACC Kid) provides specific guidance regarding overdose and required emergency actions.

Documented presentations of an acute overdose are primarily linked to the gastrointestinal system, including signs such as nausea, vomiting, and diarrhea.

Severe or life-threatening systemic outcomes, often associated with higher exposures, may also affect the cardiovascular system, leading to hypotension (low blood pressure) and tachycardia (rapid heartbeat), and the respiratory system, potentially causing bronchospasm or dyspnea (difficulty breathing). Fatal adverse events have been reported in the context of overdosage.

When to Seek Help

When a suspected overdose occurs, immediate medical attention or advice must be sought at once. This is also mandated if serious systemic signs, such as recurring skin or mucosal lesions, are observed.

The regulatory basis for overdose treatment is symptomatic and supportive care, as there is no specific antidote known for Acetylcysteine overdose. Management procedures include immediately discontinuing the product and ensuring the patient's airways are kept clear of secretions, a necessary action that may necessitate specialized care.

Therapeutic Uses of ACC Kid

What ACC Kid Treats: Main Uses and Benefits

This medication is generally used to provide supportive relief when respiratory symptoms include significant chest congestion and a persistent cough with phlegm that is difficult to clear. It is applied across conditions involving episodic or fluctuating manifestations like acute bronchitis, pneumonia, and tracheobronchitis, or during periods of heightened symptoms in chronic conditions such as cystic fibrosis or chronic bronchopulmonary diseases.

“The symptomatic support offered by Acetylcysteine is relevant when highly viscous mucus creates noticeable physiological strain and interferes with daily comfort.”

The core benefit may assist with managing symptoms related to highly tenacious mucus. This action helps ease the overall symptom burden and may assist the patient during difficult episodes by supporting a more manageable experience of coughing and breathing. In addition to these uses, the active ingredient is applied in a distinct, specialized therapeutic domain as an antidote relevant to critical care, where it may assist with supporting the patient against acute systemic stress, contributing to the management of potential liver injury resulting from acetaminophen toxicity.


Quick Fact: Relief for Respiratory Congestion

Property Description
Primary Goal Contributes to the symptomatic relief of airway congestion and tenacious mucus.
Symptom Focus Viscid secretions, difficult phlegm, and chest pressure.
Use Contexts Adjuvant therapy in acute respiratory infections and chronic secretory disorders.
Specialized Benefit Antidotal support against acetaminophen toxicity.

Regulatory References

  1. NIH MedlinePlus overview

Eligibility and Restrictions for Use

Eligibility for ACC Kid — Official Regulatory Information

The eligibility for this medicine, which contains acetylcysteine, is strictly defined by regulatory health authorities and is based on age, existing medical conditions, and hypersensitivity. This medicine must not be used in children under 2 years of age as this age group is at a heightened, officially documented risk of airway obstruction, a physiological constraint that prevents use.

Populations that are absolutely contraindicated (prohibited) from using this product include:

  • Patients with known hypersensitivity or allergy to the active substance, acetylcysteine, or to any of the product's inactive ingredients.
  • Patients with active peptic ulceration or a current stomach ulcer.

Restrictions and Special Considerations

The label defines other populations for whom use is restricted or requires caution. Use is not recommended or requires special consideration in patients with a history of bronchial asthma or a hyperactive bronchial system, as this increases the risk of acute bronchospasm. Women who are pregnant or breast-feeding are also advised to avoid use unless specifically directed by a healthcare professional after a careful risk assessment, as official data on safety is often limited.

What should I know about interactions with other medicines?

Prohibited Combinations and Pharmacodynamic Effects

Co-administration with antitussive medicines (cough suppressants) is advised against. This restriction represents functional antagonism, as the reduction of the cough reflex prevents the necessary clearance of the secretions liquefied by Acetylcysteine, potentially resulting in the accumulation of mucus in the airways. A separate pharmacodynamic potentiation is documented with Nitroglycerin and related organic nitrates. Concurrent use may enhance the vasodilatory effects of these agents, which can lead to clinically significant hypotension and potential headache.


Administration Timing and Exposure Alterations

A mandatory time separation is required for specific oral antibiotics, including Cephalosporins. These antibiotics must be administered at least two hours before or after Acetylcysteine to mitigate the risk of in vitro chemical inactivation. The co-administration of Acetylcysteine may also result in a formal exposure modification of Carbamazepine, potentially leading to its sub-therapeutic plasma concentrations. Due to potential chemical incompatibility, the Acetylcysteine solution should not be mixed with any other medicinal products.


Analytical and Excipient Considerations

Official documents note that Acetylcysteine may cause analytical interference by altering the results of specific laboratory tests, including colorimetric assays for salicylates and certain tests for ketones in urine. Additionally, the preparation contains sodium, which is a factor for patients with conditions sensitive to increased sodium intake, such as congestive heart failure or hypertension.

Mechanism of Action

Direct Chemical Breakdown (Mucolysis)

The primary mechanism involves direct chemical reduction of highly viscous mucus. The active ingredient supplies a free sulfhydryl group ( SH group) that chemically attacks and breaks the disulfide bonds ( S-S bonds) connecting large mucin proteins. This action depolymerizes the mucus structure, sharply reducing its viscosity and reducing the resistance of secretions to movement.


️ Functional Secretolytic Clearance

The molecular change initiated by the drug creates a physiological cascade that leads to a secretolytic effect. By reducing the adhesion of the mucus polymers, the resulting change in physical properties lowers the burden on the body's mucociliary transport system's function. This facilitates the physical clearance of tenacious respiratory secretions.


Supporting Antioxidant Defense

The molecule acts as a precursor for the cellular antioxidant, Glutathione ( GSH), within the respiratory tract. This mechanism provides the necessary component for the replenishment of local GSH stores, which modulates oxidative stress in the airway environment. This action contributes to the mitigation of damage from ROS to the ciliary components.

Dosage and Administration Information

How ACC Kid is Used: Official Administration Guidelines

This section describes the high-level, standardized usage principles for Acetylcysteine, the active ingredient in ACC Kid. These instructions address administration, preparation, and specific dosing parameters, but do not cover clinical decision-making or safety information.


Administration Scope

Property Description
Route of Administration The ACC Kid formulation is taken orally. The active substance is also approved for Intravenous (IV), Inhalation, and Direct Instillation routes in other specialized formulations.
Dosing Schedule The official mucolytic dose for Adults and Children over 7 years is typically 600 mg daily. For Children aged 2 to 7 years, the regimen specifies 400 mg daily. The specialized antidote use requires a strict weight-based loading and maintenance dose (mg/kg).
Frequency Pattern For mucolytic use, the total daily dose is administered once daily or may be divided into two or three doses per day.

Procedural and Time-Based Instructions

Preparation Requirements: The effervescent tablet or powder must be fully dissolved in a glass of drinking water before ingestion, and the resulting solution must be consumed immediately after preparation. Taking the medicine after a meal may be advised in some contexts, and abundant fluid intake is recommended to support the physical action of the medicine.

Age-Group Rules: Mucolytic agents like this are not indicated for children under two years of age.

Duration and Procedural Constraints: Treatment for acute conditions requires clinical re-evaluation if no improvement is noted after a short period, typically five days. For the critical oral antidote protocol, a dose that is vomited within one hour of administration must be repeated.


These official administration instructions define the structured procedure for using the medicine, mandating specific preparation steps and setting clear numerical boundaries for age-based daily doses and treatment duration for acute episodes.

Recent Clinical Evidence

Research Evidence Overview for ACC Kid

Evidence for Mucolytic Use in Acute Respiratory Infections

Research has examined the use of the active ingredient in ACC Kid in short-term studies for acute respiratory conditions characterized by tenacious mucus, such as acute bronchitis. The evidence base for this population consists of short-term Randomized Controlled Trials (RCTs) and subsequent large Systematic Reviews. These studies focused on measuring high-level outcomes like the time to resolution of symptoms and scores reflecting changes in clinical status.

Research so far has explored the outcomes in studies where the medicine was evaluated during periods of increased symptom activity. The findings describe patterns in the short-term change of symptoms. This research reports changes measured during the study period for outcomes related to physical discomfort and chest congestion. However, the evidence base contains limitations, including high variability across studies in terms of administration method and the specific dose used.

Evidence for Use in Chronic Secretory Conditions

The active ingredient was evaluated in studies for long-term respiratory concerns, focusing on periods of heightened symptom activity in conditions like chronic bronchitis or Cystic Fibrosis. Research focused on outcomes reflecting daily functioning or activity level, including measurements of lung function and the frequency of episodic or acute changes.

In the context of chronic use, findings were mixed. Some studies reported how symptoms evolved, describing patterns related to changes in the number of flare-ups experienced over time. Conversely, research exploring functional outcomes, such as sustained changes in lung capacity, showed patterns that appear to be small or inconsistent across different trials.

Distinct Research Focus: Antidotal Use in Critical Care

In a separate, highly specialized context, the active ingredient was studied for its use as an antidote in the critical care management of acetaminophen toxicity. The research in this domain focused on critical outcomes, such as patient outcomes related to acute systemic stress and the prevention of severe liver injury. The evidence base for this specific use is supported by high-certainty data and is documented extensively in regulatory guidance, but it involves significantly higher doses and completely different administration protocols.

What Remains Uncertain About the Research Evidence

The available research highlights what is known — and what is still uncertain. A research limitation frame is that data remain insufficient for long-term outcomes that exceed six months. Follow-up durations were limited in many of the key trials, meaning that long-term effects are not fully established. Additionally, subgroup findings are uncertain, as the consistency of response across various ages and conditions is not fully established.

Key Studies & References Plain Language Summary: N-acetylcysteine in paediatrics: a review of efficacy, safety and dosing strategies in respiratory care - Drugs in Context

Frequently Asked Questions (FAQ)

Common questions about ACC Kid (FAQ)


Q: Is ACC Kid the same as regular ACC, just a smaller dose?

A: ACC Kid contains the same active ingredient, Acetylcysteine, found in other ACC formulations. The main difference is the dose and format, which is specifically tailored for children in certain age groups. Official regulatory information shows the daily dose for young children is lower than the typical standard adult dose.

Q: Is it normal for a child to feel a little nauseous after taking ACC Kid?

A: Yes, regulatory documents indicate that nausea and vomiting are commonly reported, non-serious effects of the active ingredient, Acetylcysteine. If a child experiences symptoms that are severe or do not resolve, it is recommended that parents seek guidance from a qualified healthcare professional.

Q: Can ACC Kid be used for a dry cough or only a chesty one?

A: According to official therapeutic indications, Acetylcysteine is intended for respiratory disorders that involve thick, viscous mucus hypersecretion. This means it is primarily used for productive, or 'chesty,' coughs where the goal is to thin and clear mucus, not for dry cough suppression.

Q: Can a child take ACC Kid if they also have a fever?

A: Regulatory documents note that fever (pyrexia) is listed as an uncommon side effect of the medicine. However, official information does not place a restriction on taking the medicine when a child already has a pre-existing fever.

Q: Does ACC Kid interact with common cold or flu medications for kids?

A: Official information contains specific warnings regarding co-administration with cough suppressants (antitussive medicines) and requires a two-hour separation from certain oral antibiotics. Interactions with general cold or flu combination medications are not addressed as a class, so the combination should be reviewed with a healthcare provider.

Q: What foods or drinks should be avoided while a child is taking ACC Kid?

A: There are no specific foods or drinks listed in regulatory information that must be strictly avoided. The product information indicates that the medicine should be dissolved in drinking water for consumption, and that the resulting solution should be taken right away. It should not be mixed with any other medicines or substances before ingestion.

Q: Is ACC Kid considered an antibiotic or a decongestant?

A: ACC Kid is classified pharmacologically as a mucolytic (or secretolytic) agent. This means its job is to break down mucus. Official product information confirms that it is not classified as an antibiotic to fight bacterial infection or as a decongestant to relieve nasal swelling.

Q: Can ACC Kid be used for chronic lung conditions?

A: Yes, the active ingredient is officially approved for use as an additional therapy for patients with chronic bronchopulmonary diseases, such as chronic bronchitis or cystic fibrosis, where thick mucus is a primary concern. Use of this medicine for chronic conditions requires supervision and assessment by a healthcare professional.

Q: Can ACC Kid cause a rash or other allergic reaction?

A: Official safety data indicates that the active ingredient may cause hypersensitivity reactions, which can include a rash. Very rarely, severe skin reactions, known as SCARs, have been reported, primarily during the initial stages of treatment. Individuals with a known allergy to Acetylcysteine are officially advised not to use the product.

Q: Should ACC Kid be taken with food, or does it matter?

A: According to official regulatory documents, the medicine can be taken with or without food. Taking it after a meal may sometimes be suggested to help minimize the potential for minor gastrointestinal side effects like nausea.

Q: Does ACC Kid contain sugar or artificial sweeteners that might be a concern?

A: Formulations often include excipients like sucrose (sugar) and aspartame, which is a source of phenylalanine. This composition may be a concern for patients with certain rare hereditary conditions, and they should consult the official label for full details.

Q: Does ACC Kid interact with vitamins or supplements?

A: Regulatory documents advise that the medicine may reduce the absorption of salts of some metals, such as iron, calcium, and gold. Official information suggests separating the administration of these supplements by at least two hours. Interactions with other general vitamins or supplements are not uniformly documented.

Q: Can ACC Kid affect a child's appetite?

A: While an explicit change in appetite is not listed as a side effect, the medicine commonly causes nausea and vomiting. These temporary gastrointestinal effects may indirectly reduce a child's desire to eat while the medicine is being taken.

Q: Is it true that ACC Kid is also sometimes used for conditions other than lung congestion?

A: Yes, in a completely separate and highly specialized medical context, the active ingredient is officially indicated and used as a life-saving antidote. This is specifically for the critical care management of acetaminophen (paracetamol) overdose.

Q: Are there specific instructions for preparing the ACC Kid solution?

A: Official guidance notes that the effervescent tablet or powder should be fully dissolved in a glass of drinking water. Once the medicine is fully dissolved, the solution must be consumed immediately and should not be stored for later use.

Q: Why does ACC Kid sometimes have a sulfur-like smell?

A: The sulfur-like smell is an expected and normal characteristic of the active substance, Acetylcysteine. The molecule is a sulfur-containing compound containing a free sulfhydryl group ( SH group), which contributes to the mechanism of action and the odor.

Q: What is the maximum number of days a child should take ACC Kid consecutively?

A: According to official product information, generally, use for symptomatic treatment beyond 8 to 10 days requires clinical re-evaluation. For acute conditions, assessment is required if no improvement is seen after typically five days.

Q: Can children with liver or kidney issues take ACC Kid?

A: The product information indicates that caution should be exercised in patients with conditions sensitive to increased sodium intake, such as heart failure, because the preparation contains sodium. Specific official guidance regarding the use of the oral mucolytic formulation in children with significant kidney or liver impairment is not uniformly provided, but specialized advice is often needed.

Q: Is it okay to give ACC Kid right before bedtime?

A: The official side effect profile of the active ingredient does not list insomnia (difficulty sleeping) or drowsiness. This indicates that the medicine is not known to affect sleep or cause sedation, so the timing relative to bedtime is generally acceptable.

Q: Does ACC Kid need to be refrigerated after opening?

A: No, the unopened product should be stored below 25 C and protected from moisture. However, the solution created by dissolving the powder or tablet must be used immediately and should never be stored for later use, even in a refrigerator.

Q: Is the taste of ACC Kid meant to be sour or sweet?

A: Official regulatory information does not formally define the specific taste profile, but the formulations often contain flavorings like orange and sweeteners like sucrose or saccharin sodium. These are included to improve the palatability for children.

Q: Can a child with known drug sensitivities use ACC Kid?

A: The medicine is strictly contraindicated (prohibited) for any patient who has a known history of hypersensitivity or allergy to the active substance, Acetylcysteine, or to any of the product's inactive ingredients. Consultation with a healthcare provider is necessary when considering use in a child with general drug sensitivities.

Q: Does the efficacy of ACC Kid change if it's mixed with juice instead of water?

A: The official instructions strictly mandate that the medicine must be dissolved in drinking water. Regulatory documents advise against mixing the solution with any other medicinal products or beverages, including juices, because mixing with other liquids is advised against because of potential chemical and physical incompatibilities.

Q: Is it normal to see more coughing immediately after starting ACC Kid?

A: It is possible. Regulatory guidance explains that the medicine works by liquefying or thinning the bronchial secretions, which can temporarily increase the volume of mucus. This increase in volume often results in the need for increased coughing to effectively clear the secretions from the airways.

How should ACC Kid be stored and disposed of?

How to Store and Dispose of ACC Kid

This information reflects the official storage, handling, and disposal requirements as documented in governmental regulatory labeling for ACC Kid (Acetylcysteine 100 mg).

Requirement Official Regulatory Statement
Temperature Do not store the unopened product above 25 C.
Protection Store in the original package/sachet to protect from moisture, and keep the container tightly closed.
Stability (Reconstituted) The solution must be used immediately after dissolving and should not be stored for later use.
Child Safety Keep this medicine out of the sight and reach of children.
Disposal Do not dispose of unused or expired medicine via wastewater or household waste. Return the product to a pharmacist or designated collection point for environmentally sound disposal.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

Available in countries:

Equivalent of ACC Kid found in:

A-Z Index: