Components:
Trihexyphenidyl
Trihexyphenidyl
Method of action:
Anticholinergic, Antiparkinsonian, M-Holinoblocking
Anticholinergic, Antiparkinsonian, M-Holinoblocking
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Name of the medicinal product

ACA (ANTICHOLINERGIC)

Qualitative and quantitative composition

Trihexyphenidyl

Therapeutic indications

The information provided in Therapeutic indications of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Therapeutic indications in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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ACA (ANTICHOLINERGIC) is an antispasmodic drug which exerts a direct inhibitory effect on the parasympathetic nervous system. It also has a relaxing effect on smooth muscle.

It is indicated in all forms of Parkinsonism (postencephalitic, arteriosclerotic and idiopathic). It is often useful as adjuvant therapy when treating these forms of Parkinsonism with levodopa. ACA (ANTICHOLINERGIC) is effective in reducing the rigidity of muscle spasm, tremor and excessive salivation associated with Parkinsonism. ACA (ANTICHOLINERGIC) is also indicated to control extrapyramidal disorders (eg akathisia manifested by extreme restlessness and dyskinesia characterised by spastic contractions and involuntary movements) due to central nervous system drugs such as reserpine and the phenothiazines.

Dosage (Posology) and method of administration

The information provided in Dosage (Posology) and method of administration of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Dosage (Posology) and method of administration in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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Adults only: Optimal dosage should always be determined empirically, usually by initiating therapy at a relatively low level and by subsequent graduated increments.

The usual dosage for Parkinsonism is 6-10mg per day although some patients chiefly in the post-encephalitic group may require an average total dose of 12-15mg daily. It should be given orally either three or four times a day at mealtimes.

Normal dosage for drug-induced Parkinsonism is usually between 5mg and 15mg per day, although some cases have been controlled by 1mg daily.

In all cases, ACA (ANTICHOLINERGIC) dosage should be increased or decreased only by small increments over a period of several days. In initial therapy the dose should be 1mg the first day, 2mg the second day with further increases of 2mg per day at three to five-day intervals until the optimum dose is reached.

If patients are already being treated with other parasympathetic inhibitors, ACA (ANTICHOLINERGIC) should be substituted as part of the therapy. When ACA (ANTICHOLINERGIC) is used concomitantly with levodopa the usual dose of each may need to be reduced. Careful adjustment is necessary, depending on side effects and the degree of symptom control. ACA (ANTICHOLINERGIC) dosage of 3-6mg daily in divided doses, is usually adequate.

ACA (ANTICHOLINERGIC) may be taken before or after meals according to the way the patient reacts. If ACA (ANTICHOLINERGIC) tends to dry the mouth excessively, it may be better to take it before meals, unless it causes nausea. If taken after meals, induced thirst can be allayed by peppermint, chewing gum or water.

Treatment of drug-induced extrapyramidal disorder: The size and frequency of dose of ACA (ANTICHOLINERGIC) needed to control extrapyramidal reactions to commonly employed tranquillisers, notably the phenothiazines, thioxanthenes, and butyrophenones must be determined empirically. The total daily dosage usually ranges between 5 and 15mg, although in some cases, these reactions have been controlled by as little as 1mg daily.

Satisfactory control may sometimes be more rapidly achieved by temporarily reducing the dosage of both drugs until the desired ataractic effect is retained without concomitant extrapyramidal reactions.

It is sometimes possible to maintain the patient on reduced ACA (ANTICHOLINERGIC) dosage after the reactions have remained under control for several days. Since these reactions may remain in remission for long periods after discontinuation of ACA (ANTICHOLINERGIC) therapy, such therapy should be of minimal duration and discontinued after symptoms have subsided for a reasonable period of time.

Elderly: Patients over 65 years of age tend to be relatively more sensitive and require smaller amounts of the drug.

Children: Not recommended.

Contraindications

The information provided in Contraindications of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Contraindications in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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Hypersensitivity to ACA (ANTICHOLINERGIC) or any of the other ingredients.

Special warnings and precautions for use

The information provided in Special warnings and precautions for use of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Special warnings and precautions for use in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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Precautions: Since the use of ACA (ANTICHOLINERGIC) may, in some cases, continue indefinitely, the patient should be under careful observation over the long term. It should be administered with care to avoid allergic or other untoward reactions.

Except in the case of vital complications, abrupt discontinuation of the drug should be avoided.

Incipient glaucoma may be precipitated by para-sympatholytic drugs such as ACA (ANTICHOLINERGIC).

Hypertension, cardiac, liver or kidney disorders are not contra-indicated, but such patients should be followed closely. As ACA (ANTICHOLINERGIC) may provoke or exacerbate tardive dyskinesia, it is not recommended for use in patients with this condition.

ACA (ANTICHOLINERGIC) should be used with caution in patients with glaucoma, obstructive disease of the gastro-intestinal or genito-urinary tracts, and in elderly males with possible prostatic hypertrophy.

Since ACA (ANTICHOLINERGIC) has been associated with the clinical worsening of myasthenia gravis, the drug should be avoided or used with great caution in patients with this condition.

Since certain psychiatric manifestations such as confusion, delusions and hallucinations, all of which may occur with any of the atropine-like drugs, have been reported rarely with ACA (ANTICHOLINERGIC), it should be used with extreme caution in elderly patients (see Dosage and Administration).

Warnings: ACA (ANTICHOLINERGIC) may be the subject of abuse (on the basis of hallucinogenic or euphoriant properties, common to all anti-cholinergic drugs) if given in sufficient amounts.

Effects on ability to drive and use machines

The information provided in Effects on ability to drive and use machines of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Effects on ability to drive and use machines in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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Can cause blurring of vision, dizziness and mild nausea. Also mental confusion in some cases.

Undesirable effects

The information provided in Undesirable effects of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Undesirable effects in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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Modern clinical data required to determine the frequency of undesirable effects are lacking for ACA (ANTICHOLINERGIC). Minor side effects such as dryness of mouth, constipation, blurring of vision, dizziness, mild nausea or nervousness will be experienced by 30-50% of all patients. These reactions tend to become less pronounced as treatment continues. Patients should be allowed to develop a tolerance using the smaller initial dose until an effective level is reached.

Immune system disorders: Hypersensitivity.

Psychiatric disorders: Nervousness, restlessness, confusional states, agitation, delusions, hallucinations, insomnia, especially in the elderly and patients with arteriosclerosis. The development of psychiatric disturbances may necessitate discontinuation of treatment.

Euphoria may occur. There have been reports of abuse of ACA (ANTICHOLINERGIC) due to its euphoric and hallucinogenic properties.

Nervous system disorders: Dizziness.

Impairment of immediate and short-term memory function has been reported.

Worsening of myasthenia gravis may occur .

Eye disorders: Dilatation of the pupils with loss of accommodation and photophobia, raised intraocular pressure .

Cardiac disorders: Tachycardia.

Respiratory, thoracic and mediastinal disorders: Decreased bronchial secretions.

Gastrointestinal disorders: Dry mouth with difficulty swallowing, constipation, nausea, vomiting.

Skin and subcutaneous tissue disorders: Flushing and dryness of skin, skin rashes.

Renal and urinary disorders: Urinary retention, difficulty in micturition.

General disorders: Thirst, pyrexia.

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard

Overdose

The information provided in Overdose of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Overdose in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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Symptoms: Symptoms of overdose with antimuscarinic agents include flushing and dryness of the skin, dilated pupils, dry mouth and tongue, tachycardia, rapid respiration, hyperpyrexia, hypertension, nausea, vomiting. A rash may appear on the face or upper trunk. Symptoms of CNS stimulation include restlessness, confusion, hallucinations, paranoid and psychotic reactions, incoordination, delirium and occasionally convulsions. In severe overdose, CNS depression may occur with coma, circulatory and respiratory failure and death.

Treatment: Treatment should always be supportive. An adequate airway should be maintained. Diazepam may be administered to control excitement and convulsions but the risk of central nervous system depression should be considered. Hypoxia and acidosis should be corrected. Antiarrhythmic drugs are not recommended if dysrhythmias occur.

Pharmacodynamic properties

The information provided in Pharmacodynamic properties of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Pharmacodynamic properties in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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ACA (ANTICHOLINERGIC) hydrochloride is an anticholinergic agent. It is an antispasmodic drug which exerts a direct inhibitory effect on the parasympathetic nervous system. It diminishes salivation, increases the heart rate, dilates the pupils and reduces spasm of smooth muscle.

Pharmacokinetic properties

The information provided in Pharmacokinetic properties of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Pharmacokinetic properties in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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ACA (ANTICHOLINERGIC) hydrochloride is well absorbed from the gastrointestinal tract. It disappears rapidly from the plasma and tissues and does not accumulate in the body during continued administration of conventional doses.

Preclinical safety data

The information provided in Preclinical safety data of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Preclinical safety data in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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None stated.

Incompatibilities

The information provided in Incompatibilities of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Incompatibilities in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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None.

Special precautions for disposal and other handling

The information provided in Special precautions for disposal and other handling of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Special precautions for disposal and other handling in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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No special requirements.

Name of the medicinal product
ACA (ANTICHOLINERGIC)
Qualitative and quantitative composition
Trihexyphenidyl
Therapeutic indications
The information provided in Therapeutic indications of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Therapeutic indications in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
more... close

ACA (ANTICHOLINERGIC) is an antispasmodic drug which exerts a direct inhibitory effect on the parasympathetic nervous system. It also has a relaxing effect on smooth muscle.

It is indicated in all forms of Parkinsonism (postencephalitic, arteriosclerotic and idiopathic). It is often useful as adjuvant therapy when treating these forms of Parkinsonism with levodopa. ACA (ANTICHOLINERGIC) is effective in reducing the rigidity of muscle spasm, tremor and excessive salivation associated with Parkinsonism. ACA (ANTICHOLINERGIC) is also indicated to control extrapyramidal disorders (eg akathisia manifested by extreme restlessness and dyskinesia characterised by spastic contractions and involuntary movements) due to central nervous system drugs such as reserpine and the phenothiazines.

Dosage (Posology) and method of administration
The information provided in Dosage (Posology) and method of administration of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Dosage (Posology) and method of administration in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
more... close

Adults only: Optimal dosage should always be determined empirically, usually by initiating therapy at a relatively low level and by subsequent graduated increments.

The usual dosage for Parkinsonism is 6-10mg per day although some patients chiefly in the post-encephalitic group may require an average total dose of 12-15mg daily. It should be given orally either three or four times a day at mealtimes.

Normal dosage for drug-induced Parkinsonism is usually between 5mg and 15mg per day, although some cases have been controlled by 1mg daily.

In all cases, ACA (ANTICHOLINERGIC) dosage should be increased or decreased only by small increments over a period of several days. In initial therapy the dose should be 1mg the first day, 2mg the second day with further increases of 2mg per day at three to five-day intervals until the optimum dose is reached.

If patients are already being treated with other parasympathetic inhibitors, ACA (ANTICHOLINERGIC) should be substituted as part of the therapy. When ACA (ANTICHOLINERGIC) is used concomitantly with levodopa the usual dose of each may need to be reduced. Careful adjustment is necessary, depending on side effects and the degree of symptom control. ACA (ANTICHOLINERGIC) dosage of 3-6mg daily in divided doses, is usually adequate.

ACA (ANTICHOLINERGIC) may be taken before or after meals according to the way the patient reacts. If ACA (ANTICHOLINERGIC) tends to dry the mouth excessively, it may be better to take it before meals, unless it causes nausea. If taken after meals, induced thirst can be allayed by peppermint, chewing gum or water.

Treatment of drug-induced extrapyramidal disorder: The size and frequency of dose of ACA (ANTICHOLINERGIC) needed to control extrapyramidal reactions to commonly employed tranquillisers, notably the phenothiazines, thioxanthenes, and butyrophenones must be determined empirically. The total daily dosage usually ranges between 5 and 15mg, although in some cases, these reactions have been controlled by as little as 1mg daily.

Satisfactory control may sometimes be more rapidly achieved by temporarily reducing the dosage of both drugs until the desired ataractic effect is retained without concomitant extrapyramidal reactions.

It is sometimes possible to maintain the patient on reduced ACA (ANTICHOLINERGIC) dosage after the reactions have remained under control for several days. Since these reactions may remain in remission for long periods after discontinuation of ACA (ANTICHOLINERGIC) therapy, such therapy should be of minimal duration and discontinued after symptoms have subsided for a reasonable period of time.

Elderly: Patients over 65 years of age tend to be relatively more sensitive and require smaller amounts of the drug.

Children: Not recommended.

Contraindications
The information provided in Contraindications of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Contraindications in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
more... close

Hypersensitivity to ACA (ANTICHOLINERGIC) or any of the other ingredients.

Special warnings and precautions for use
The information provided in Special warnings and precautions for use of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Special warnings and precautions for use in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
more... close

Precautions: Since the use of ACA (ANTICHOLINERGIC) may, in some cases, continue indefinitely, the patient should be under careful observation over the long term. It should be administered with care to avoid allergic or other untoward reactions.

Except in the case of vital complications, abrupt discontinuation of the drug should be avoided.

Incipient glaucoma may be precipitated by para-sympatholytic drugs such as ACA (ANTICHOLINERGIC).

Hypertension, cardiac, liver or kidney disorders are not contra-indicated, but such patients should be followed closely. As ACA (ANTICHOLINERGIC) may provoke or exacerbate tardive dyskinesia, it is not recommended for use in patients with this condition.

ACA (ANTICHOLINERGIC) should be used with caution in patients with glaucoma, obstructive disease of the gastro-intestinal or genito-urinary tracts, and in elderly males with possible prostatic hypertrophy.

Since ACA (ANTICHOLINERGIC) has been associated with the clinical worsening of myasthenia gravis, the drug should be avoided or used with great caution in patients with this condition.

Since certain psychiatric manifestations such as confusion, delusions and hallucinations, all of which may occur with any of the atropine-like drugs, have been reported rarely with ACA (ANTICHOLINERGIC), it should be used with extreme caution in elderly patients (see Dosage and Administration).

Warnings: ACA (ANTICHOLINERGIC) may be the subject of abuse (on the basis of hallucinogenic or euphoriant properties, common to all anti-cholinergic drugs) if given in sufficient amounts.

Effects on ability to drive and use machines
The information provided in Effects on ability to drive and use machines of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Effects on ability to drive and use machines in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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Can cause blurring of vision, dizziness and mild nausea. Also mental confusion in some cases.

Undesirable effects
The information provided in Undesirable effects of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Undesirable effects in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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Modern clinical data required to determine the frequency of undesirable effects are lacking for ACA (ANTICHOLINERGIC). Minor side effects such as dryness of mouth, constipation, blurring of vision, dizziness, mild nausea or nervousness will be experienced by 30-50% of all patients. These reactions tend to become less pronounced as treatment continues. Patients should be allowed to develop a tolerance using the smaller initial dose until an effective level is reached.

Immune system disorders: Hypersensitivity.

Psychiatric disorders: Nervousness, restlessness, confusional states, agitation, delusions, hallucinations, insomnia, especially in the elderly and patients with arteriosclerosis. The development of psychiatric disturbances may necessitate discontinuation of treatment.

Euphoria may occur. There have been reports of abuse of ACA (ANTICHOLINERGIC) due to its euphoric and hallucinogenic properties.

Nervous system disorders: Dizziness.

Impairment of immediate and short-term memory function has been reported.

Worsening of myasthenia gravis may occur .

Eye disorders: Dilatation of the pupils with loss of accommodation and photophobia, raised intraocular pressure .

Cardiac disorders: Tachycardia.

Respiratory, thoracic and mediastinal disorders: Decreased bronchial secretions.

Gastrointestinal disorders: Dry mouth with difficulty swallowing, constipation, nausea, vomiting.

Skin and subcutaneous tissue disorders: Flushing and dryness of skin, skin rashes.

Renal and urinary disorders: Urinary retention, difficulty in micturition.

General disorders: Thirst, pyrexia.

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard

Overdose
The information provided in Overdose of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Overdose in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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Symptoms: Symptoms of overdose with antimuscarinic agents include flushing and dryness of the skin, dilated pupils, dry mouth and tongue, tachycardia, rapid respiration, hyperpyrexia, hypertension, nausea, vomiting. A rash may appear on the face or upper trunk. Symptoms of CNS stimulation include restlessness, confusion, hallucinations, paranoid and psychotic reactions, incoordination, delirium and occasionally convulsions. In severe overdose, CNS depression may occur with coma, circulatory and respiratory failure and death.

Treatment: Treatment should always be supportive. An adequate airway should be maintained. Diazepam may be administered to control excitement and convulsions but the risk of central nervous system depression should be considered. Hypoxia and acidosis should be corrected. Antiarrhythmic drugs are not recommended if dysrhythmias occur.

Pharmacodynamic properties
The information provided in Pharmacodynamic properties of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Pharmacodynamic properties in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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ACA (ANTICHOLINERGIC) hydrochloride is an anticholinergic agent. It is an antispasmodic drug which exerts a direct inhibitory effect on the parasympathetic nervous system. It diminishes salivation, increases the heart rate, dilates the pupils and reduces spasm of smooth muscle.

Pharmacokinetic properties
The information provided in Pharmacokinetic properties of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Pharmacokinetic properties in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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ACA (ANTICHOLINERGIC) hydrochloride is well absorbed from the gastrointestinal tract. It disappears rapidly from the plasma and tissues and does not accumulate in the body during continued administration of conventional doses.

Preclinical safety data
The information provided in Preclinical safety data of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Preclinical safety data in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
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None stated.

Incompatibilities
The information provided in Incompatibilities of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Incompatibilities in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
more... close

None.

Special precautions for disposal and other handling
The information provided in Special precautions for disposal and other handling of ACA (ANTICHOLINERGIC) is based on data of another medicine with exactly the same composition as the ACA (ANTICHOLINERGIC) of the medicine (Trihexyphenidyl). Be careful and be sure to specify the information on the section Special precautions for disposal and other handling in the instructions to the drug ACA (ANTICHOLINERGIC) directly from the package or from the pharmacist at the pharmacy.
more... close

No special requirements.

Available in countries
See all
close