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Abrixone

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Name of the medicinal product
Qualitative and quantitative composition
Therapeutic indications
Dosage (Posology) and method of administration
Contraindications
Special warnings and precautions for use
Interaction with other medicinal products and other forms of interaction
Undesirable effects

Components:

Metadoxine

Medically reviewed by Kovalenko Svetlana Olegovna, PharmD. Last updated on 26.06.2023

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Name of the medicinal product
Abrixone
Qualitative and quantitative composition

Abrixone is pyridoxine L-2-pyrrolidone-5-carboxylate.

Therapeutic indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Oral

Acute alcohol intoxication

Adult: 500-1000 mg daily.

Oral

Alcoholic fatty liver; Supportive treatment of acute and chronic liver diseases

Adult: 1000 mg daily.

Parenteral

Acute alcohol intoxication

Adult: 300-600 mg daily IM/IV.

Parenteral

Alcoholic fatty liver; Supportive treatment of acute and chronic liver diseases

Adult: 300 mg daily IM/IV.

Dosage (Posology) and method of administration

Oral

Acute alcohol intoxication

Adult: 500-1000 mg daily.

Oral

Alcoholic fatty liver; Supportive treatment of acute and chronic liver diseases

Adult: 1000 mg daily.

Parenteral

Acute alcohol intoxication

Adult: 300-600 mg daily IM/IV.

Parenteral

Alcoholic fatty liver; Supportive treatment of acute and chronic liver diseases

Adult: 300 mg daily IM/IV.

Contraindications

Known hypersensitivity to Abrixone or to any of the components of Abrixone.

Special warnings and precautions for use
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Abrixone is used for the prevention and treatment of liver damage due to alcoholism.

Interaction with other medicinal products and other forms of interaction

Abrixone may increase the peripheral decarboxylation of levodopa, decreasing its efficacy.

Incompatibilities: With iron salts, alkaline solutions, oxidant solutions.

Undesirable effects

Hypersensitivity; abnormal movement (peripheral neuropathy); dizziness; disorientation; diarrhea; vomiting; swelling of the face, lips, tongue or throat or difficulty breathing or swallowing (angioedema); rash; skin rashes or itching skin (urticaria); itching; decreased appetite.

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