Components:
Method of action:
Treatment option:
Medically reviewed by Oliinyk Elizabeth Ivanovna, PharmD. Last updated on 25.03.2022
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Top 20 medicines with the same components:
Top 20 medicines with the same treatments:
Abalnate
Midodrine
Hypotension (caused by taking psychotropic drugs, symptomatic in the period of convalescence after surgery, childbirth, etc.), orthostatic hypotension (with violations of the regulation of blood circulation and circulatory dysregulations, with reactions such as sympathicotonia and asympathicotonia, idiopathic, secondary)
Pills: взрослым, детям подросткового возраста (12 лет и старше) — inside, по 2,5 мг 2 раза в сутки (утром и вечером), при необходимости — 3 раза в сутки, в отдельных случаях дозировка может быть сокращена до 2 раз по 1/2 табл. в сутки (2,5 мг); при одновременном назначении с седативными или снотворными средствами принимают сначала по 2,5 мг 2 раза в сутки, затем (при необходимости) дозу увеличивают до 5 мг 2–3 раза в сутки; детям до 12 лет — дозу рассчитывают в зависимости от массы тела.
Drops: взрослым, детям старше 12 лет — inside, по 7 капель 2 раза в сутки (утром и вечером), при необходимости дозу снижают до 3 капель 2 раза в сутки или в редких случаях увеличивают до 7 капель 3 раза в сутки; при комбинации с психотропными препаратами — 7 капель 2 раза в сутки или (при необходимости) по 15 капель 2–3 раза в сутки; детям до 12 лет дозируют в зависимости от массы тела.
Drops should be taken with a small amount of water or on a piece of sugar.
Hypertension, angle-closure glaucoma, pheochromocytoma, hyperthyroidism, acute nephritis, severe renal failure,mechanical obstruction of the urinary tract, prostate adenoma with residual urine.
Violation of the heart rhythm, the appearance of pain in the heart, allergic reactions (rash).
Symptoms: «гусиная» кожа, особенно в области головы (затылка) и шеи, чувство холода, задержка мочеиспускания, позывы к мочеиспусканию (как следствие), возможно (рефлекторное) замедление ЧСС (в покое ниже 60 ударов в минуту).
Treatment: применение атропина в обычных дозах.
Increases the tone and peripheral resistance of arterial vessels, increases blood pressure and prevents (in orthostatic disorders) stagnation of blood in the venous bed. This leads to the maintenance of a constant level of the volume of circulating blood and blood pressure, an increase in blood delivery to the organs and the elimination of orthostatic disorders. It does not directly affect the activity of the heart, the central nervous system (does not cause sleep disorders). Improves the function of the bladder sphincter.
When used orally, it is rapidly absorbed, becoming an active metabolite. After intravenous injection, the effect develops relatively slowly and persists for a long time. T1/2 of the active metabolite in plasma is 3-4 hours. Due to the very low lipophilicity, it practically does not penetrate through the BBB. Midodrin and its metabolites are excreted in the urine almost completely within 24 hours.
- Alpha-adrenergic agonist
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