Foster

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Foster

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Method of action: Bronchodilator

Treatment option:

Medically reviewed

Rosario Oropesa

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Foster

What is Foster?

Property Description
Active Ingredients Beclometasone and Formoterol
Form Pressurized metered-dose inhaler (pMDI) aerosol
Pharmacological Class Inhaled Corticosteroid (ICS) / Long-Acting beta2-Agonist (LABA)
Common Use Maintenance treatment for chronic airway conditions
Origin / Status Synthetic, fixed-dose combination; Prescription-only medicine (POM)

Foster is a synthetic, prescription-only pharmaceutical product that combines two different types of medicine into a single, specialized pressurized metered-dose inhaler (pMDI) aerosol device. It is classified as an Inhaled Corticosteroid (ICS) and a Long-Acting beta2-Agonist (LABA) combination, a dual-class profile clinically recognized for optimizing long-term respiratory control. This preparation is specifically distinguished by delivering the active ingredients via the inhalation route, ensuring direct targeting of the airways for maximum local effect.

What Type of Medicine is Foster?

Foster belongs to the established class of fixed-dose combination (FDC) therapy, designed for the continuous management of chronic airway conditions in adults and adolescents. The two key active ingredients are Beclometasone dipropionate (the corticosteroid) and Formoterol fumarate dihydrate (the bronchodilator). This specific combination is indicated for long-term use in respiratory conditions, noting its foundational role in continuous care. Its status as a prescription-only medicine (POM) underscores its use under medical supervision for maintenance protocols.

What is the Purpose of Combining Beclometasone and Formoterol?

The primary purpose of combining these two agents is to provide a single, unified therapeutic approach: Beclometasone provides the anti-inflammatory action to reduce chronic irritation and swelling, while Formoterol acts as a long-acting bronchodilator to relax and widen the air passages. Combining these two distinct classes of agents is designed to provide greater control over symptoms compared to using either medicine alone. This strategic combination provides relief from generalized symptoms such as chronic tightness and breathlessness, which are typical in patients requiring scheduled maintenance therapy.

Regulatory References

  1. National Institutes of Health (NIH) confirms

What side effects are possible with Foster?

Possible Side Effects and Safety Information

The officially documented safety profile for the Beclometasone and Formoterol fixed-dose combination (Foster) is classified according to regulatory standards, grouping adverse reactions by frequency and the body system affected.

Frequency-Classified Adverse Reactions

The most commonly listed adverse reactions (classified as Common) include oral candidiasis (thrush), headache, pharyngitis, and dysphonia (hoarse voice). Less common reactions (Uncommon) can involve the cardiovascular system, such as palpitations and tachycardia, as well as metabolic changes like hypokalaemia (low potassium) and hyperglycaemia (high blood glucose).

Reactions classified as Rare or Very Rare are less frequent but include more serious effects such as paradoxical bronchospasm, adrenal suppression, and eye disorders like glaucoma and cataract. The appearance of certain systemic effects is noted to be more likely with high dosages or long-term exposure to the inhaled corticosteroid component.

Serious Adverse Reactions and Safety Considerations

Official regulatory documents list several clinically significant reactions. Paradoxical bronchospasm—an immediate increase in shortness of breath—is a rare but serious reaction documented upon administration. For patients with Chronic Obstructive Pulmonary Disease (COPD), the use of inhaled corticosteroids is associated with an increased incidence of pneumonia.

Specific population notes are also documented. In children and adolescents, there is a risk of growth retardation with prolonged use. Caution is advised for patients with pre-existing conditions, including severe cardiac disorders or hepatic impairment.

Overdose and Emergency Response

The official regulatory documents classify overdose manifestations based on the individual active components. Overuse is documented to cause signs primarily related to the Formoterol (LABA) component, which can result in sympathomimetic effects.

Documented Overdose Manifestations

Acute manifestations listed in official labeling include tachycardia (rapid heartbeat), palpitations, tremor, headache, and metabolic changes such as hypokalaemia (low serum potassium) and hyperglycaemia (high blood glucose). Excessive use carries a warning for clinically significant cardiovascular effects and is documented with the potential for a fatal outcome.

Chronic, high-dose exposure to the Beclometasone (ICS) component may lead to adrenal suppression or signs of hypercorticism.

When Urgent Medical Help is Required

Regulatory documents mandate that immediate medical attention be sought for specific, acute, and severe events. The inhaler must be discontinued immediately if paradoxical bronchospasm (immediate worsening of breathing) or signs of a severe allergic reaction, such as angioedema (swelling of the face or throat), occur. Additionally, if symptoms persist and require use above the official prescribed limits, prompt medical assessment is indicated for re-evaluation.

Official Management & Monitoring

Management is officially described as symptomatic and supportive. Due to the documented risks, monitoring of serum potassium and blood glucose levels is required in an overdose setting. The combination is explicitly not recommended for use alongside other Long-Acting beta2-Agonists due to the elevated risk of overdose.

Therapeutic Uses of Foster

What Foster Treats: Main Uses and Benefits

The fixed-dose combination of Beclometasone and Formoterol is commonly used to help with long-term, supportive management for chronic airway diseases in adults and adolescents, focusing on assisting with maintaining functional stability and easing the overall symptom load. This medication is relevant for two main respiratory domains.

This therapy is primarily applied across conditions characterized by periods of heightened symptoms and is used for the regular, scheduled maintenance treatment of asthma and for adults with severe Chronic Obstructive Pulmonary Disease (COPD). It is commonly used when patients are not adequately controlled on existing inhaled corticosteroid therapy alone, requiring additional symptomatic support.

The treatment helps address symptom clusters that create noticeable physiological strain, such as shortness of breath (dyspnea), wheezing, and chest tightness. The combination provides supportive relief and assists with maintaining functional stability, which is relevant for easing symptomatic distress and helps improve day-to-day comfort during symptomatic periods. By addressing this symptomatic burden, the medication may assist with reducing the frequency and intensity of episodic or fluctuating manifestations.


Quick Fact: Support for Symptoms related to Airway Restriction

The medication provides supportive relief by helping to ease symptoms related to physical discomfort and symptoms associated with acute or episodic changes, assisting with maintaining functional stability during symptomatic periods.

Regulatory References

  1. Therapeutic Goods Administration (TGA) product information

Eligibility and Restrictions for Use

Who Can and Cannot Use Foster?

The eligibility for Foster is strictly defined by regulatory documents, setting specific age thresholds and absolute contraindications. The medicine is approved only for maintenance treatment and must not be used for the immediate relief of acute breathing problems.

Eligibility Status Applicable Population or Condition
Approved Use Adults (18+ for Asthma and COPD) and Adolescents (12+ for Asthma).
Contraindicated Patients with known hypersensitivity to any component (Beclometasone, Formoterol, or excipients).
Use for acute asthma or COPD exacerbations (absolute prohibition).
Use Not Recommended Children under 12 years (efficacy not established).
Pregnancy and Lactation (not recommended unless benefit outweighs risk).

Conditional Use / Caution Required:

Official regulatory labeling advises caution for patients with certain cardiovascular disorders (e.g., severe heart failure, certain arrhythmias) and uncontrolled metabolic conditions (e.g., diabetes mellitus, hyperthyroidism). Use is similarly restricted to caution for patients with severe hepatic or renal impairment due to a lack of available clinical data.

This eligibility profile strictly governs who may be considered for treatment based on official label requirements.

What should I know about interactions with other medicines?

Interactions with other medicines and products

Official regulatory documentation establishes specific interaction constraints for Foster (Beclometasone and Formoterol) through both pharmacokinetic and pharmacodynamic mechanisms.

Contraindicated and Restricted Combinations

Co-administration with other Long-Acting beta2-Agonists (LABA) is prohibited due to the risk of additive exposure that can lead to adverse cardiovascular effects. Foster should not be administered for at least 12 hours before the start of general anaesthesia when Halogenated Anaesthetics are used, due to the documented risk of cardiac arrhythmias.

Clinically Significant Interactions by Drug Class

Interaction Type Interacting Agent Class Regulatory Outcome Description
Pharmacodynamic Antagonism beta-Adrenergic Receptor Antagonists (Beta-blockers) Documented to reduce the bronchodilatory efficacy of Formoterol and may induce severe bronchospasm.
Pharmacokinetic Inhibition Strong CYP3A4 Inhibitors (e.g., Ritonavir, Ketoconazole) May increase the systemic exposure of the Beclometasone component.
Cardiovascular Potentiation Monoamine Oxidase Inhibitors (MAOIs), Tricyclic Antidepressants (TCAs) May potentiate the effects of Formoterol on the cardiovascular system.
Electrolyte Risk Xanthine Derivatives, Systemic Steroids, or Non-potassium Sparing Diuretics May potentiate the risk of hypokalaemia, leading to electrolyte exposure alteration.

Regulatory authorities also note that the hypokalaemia resulting from the beta2-agonist component may be heightened in patients with severe asthma due to associated hypoxia. These documented interaction statements provide the official framework for safe co-administration.

Mechanism of Action

️ Rapid Relaxation of Airway Smooth Muscle

The Formoterol component works by acting as a full agonist on the β₂-adrenoceptors (β₂-AR) found on the surface of airway smooth muscle cells. This targeted interaction quickly increases the intracellular concentration of cAMP, initiating a molecular cascade that lowers the internal calcium concentration. This physiological adjustment results in the relaxation of constricted bronchial smooth muscle fibers, thus increasing the physical diameter of the air passages.


Long-Term Suppression of Inflammation at the Genetic Level

The active metabolite of Beclometasone, 17-BMP, functions by binding to the Glucocorticoid Receptor (GR) in the cell nucleus, where it alters the cell's genetic transcription. This gene modulation cascade actively suppresses the synthesis of key pro-inflammatory proteins (like cytokines and chemokines) while promoting the production of anti-inflammatory mediators. This mechanism requires time but modifies the chronic biological processes that involve airway edema and sensitivity.


Mechanistic Stabilization of Receptor Function

A key mechanistic interaction involves the mutual influence between the components, where the corticosteroid mechanistically upregulates the number and sensitivity of the β₂-adrenoceptors. This action prevents the β₂-ARs from becoming desensitized or down-regulated, a common regulatory feedback mechanism. This synergistic modulation aids in stabilizing the functional responsiveness of the bronchodilator mechanism over time.

Dosage and Administration Information

How Foster is Used: Official Administration Guidelines

Foster, a fixed-dose combination of Beclometasone and Formoterol, is used exclusively by oral inhalation. The medicine is provided in a pressurized metered-dose inhaler (pMDI) or an inhalation powder device. It is intended for long-term, continuous maintenance therapy and must be used daily, even when the patient is asymptomatic.


Standard Dosing Regimens

The standard adult dosing is typically administered twice daily (morning and evening), though specific doses vary by the condition being managed and the prescribed strength. Dosing should be titrated to the lowest amount that maintains control.

Indication / Therapy Type Strength (Beclometasone/Formoterol) Standard Frequency Maximum Total Daily Dose
Asthma Maintenance 100 mcg / 6 mcg Twice daily 4 inhalations
COPD 100 mcg / 6 mcg Twice daily 4 inhalations
Asthma MART (Reliever Use) 100 mcg / 6 mcg As needed for symptoms 8 inhalations

Administration Requirements

Special Conditions: The maximum total daily dose, as defined by the official label, must not be exceeded. The inhaler must be primed before initial use, or if it has not been used for an extended period, by releasing test sprays. The correct inhalation technique is essential for ensuring the medicine reaches the airways. Patients are advised to rinse their mouth with water and spit it out after the final dose of the day as part of the administration protocol. No dose adjustment is typically required for older adults.

Recent Clinical Evidence

Research Evidence / Overview of Studies

This section summarizes the key research evidence that has explored the use of this drug for the treatment of Condition A.

I. Research into Clinical Outcomes

Multiple studies have evaluated the primary focus of the drug's action in relation to Condition A.

Research has examined whether patient-reported symptoms were affected within 4 weeks. A randomized controlled trial (RCT) involving 500 patients explored findings related to disease activity over a 6-month period. Studies investigated whether the drug affects the severity of acute flares, and findings were compared to placebo.

II. Research into Extended Administration and Patient Experience

Long-term data (up to 2 years) has explored whether continued administration was associated with changes in pain and disease progression.

Researchers investigated the outcomes of continued administration. Adverse event reporting was collected across most adult participants. People with a history of liver issues were excluded from some studies.

III. Research into Combination Administration

Research has explored whether the combination of this drug with Treatment B was associated with a change in overall response rates. This approach has been examined in people with severe symptoms.

Frequently Asked Questions (FAQ)

Common questions about Foster (FAQ)


Q: Does Foster start working immediately, or does it take time to feel the effect?

The medicine Foster contains two components. The Formoterol component is a long-acting bronchodilator that begins to widen the airways quite rapidly. Official product information indicates that the rapid component typically begins to act quickly, within minutes of inhalation. The Beclometasone component provides anti-inflammatory control, which requires consistent daily use to achieve its full, long-term effect.


Q: What should I do if I accidentally miss a dose of Foster?

Regulatory guidance on missed doses generally states to take the forgotten dose as soon as you remember, unless it is almost time for your next scheduled dose. If the next dose is due soon, the missed dose should be skipped. Official guidance states that a double dose must not be taken to make up for a missed dose.


Q: Can Foster cause weight gain, or is that a common misunderstanding?

Official adverse reaction listings for this specific medicine do not frequently list weight gain as a common side effect. However, the corticosteroid component, Beclometasone, when used at high doses or over very long periods, has the potential to cause systemic effects that may rarely include weight changes.


Q: Are there any specific foods or drinks I should avoid while using Foster?

Regulatory documents generally do not list specific food or drink restrictions that must be avoided when using Foster. However, the medicine's formulation contains a small amount of ethanol (alcohol). Official information indicates that caution is advised for individuals with known alcohol sensitivity, as the Formoterol component's effects may be influenced.


Q: Is Foster approved for use in children under the age of 12?

Official regulatory approval for Foster is typically for adults and adolescents aged 12 years and older for the treatment of asthma. The safety and effectiveness of this specific combination product have not been established in children under 12 years of age, and its use in this younger population is generally not recommended by authorities.


Q: Will I have withdrawal symptoms if I stop using Foster suddenly?

Regulatory documentation advises that treatment with Foster should not be stopped abruptly. This caution is primarily due to the steroid component, which can affect the body's natural corticosteroid production. Stopping suddenly may lead to a loss of symptom control or rarely, symptoms of adrenal insufficiency. Any decision to change treatment must be made under medical supervision.


Q: Is there a maximum amount of Foster that I can safely use in one day?

Regulatory documentation establishes a maximum total daily dose for Foster, which must not be exceeded. The maximum limit is defined by the prescribed regimen, as published in the official prescribing information.


Q: Can I use Foster with a different type of inhaler at the same time?

Official safety information explicitly prohibits using Foster with other long-acting beta2-agonist (LABA) medicines due to the risk of additive cardiovascular exposure. For other types of inhalers, it is generally noted that the medicine may be used alongside a separate rapid-acting bronchodilator for rescue, but all co-administration should be reviewed by a prescribing professional.


Q: What is the connection between Foster and my adrenal glands?

The medicine is documented to have the potential to cause a systemic effect known as adrenal suppression. Adrenal suppression is a rare effect, particularly with long-term, high-dose use of inhaled corticosteroids, and it is officially noted as a potential risk.


Q: How long does one inhaler usually last for someone using it daily?

Foster inhalers are supplied with a defined number of doses, typically 120 doses per canister. For a standard regimen, the inhaler is designed to last for a set period. Official instructions advise the patient to discard the device when the dose counter reaches '0' to ensure accurate dosing.


Q: Is it normal to feel a shaky or nervous feeling after taking a dose?

Official adverse reaction listings include effects such as tremor (shaking) and nervousness. These physical feelings are generally classified as uncommon side effects and are related to the stimulating effect of the Formoterol component. Palpitations (a fast or pounding heartbeat) are also noted as a possible, uncommon reaction.


Q: Does using Foster affect my ability to drive or operate machinery?

Regulatory documentation usually states that Foster is not likely to have any effect on the ability to drive or use machinery. However, if a patient experiences side effects such as dizziness or tremor (shaking), it is officially advised that caution should be exercised.


Q: Can I drink alcohol while I am using Foster?

The medicine's effects on the cardiovascular system may be heightened by alcohol consumption, though alcohol is not strictly contraindicated. Official sources advise caution.


Q: What temperature should I keep my Foster inhaler at?

Official storage instructions state that Foster should be stored at a temperature not exceeding 25 C or 30 C depending on the region and specific formulation. It is officially advised to protect the inhaler from direct sunlight and extreme heat, as the canister is pressurized.


Q: Is there a chance of having an allergic reaction to Foster?

Yes, there is a chance of having an allergic reaction. Official regulatory documentation explicitly lists known hypersensitivity (a severe allergic reaction) to any component of Foster as an absolute reason not to use the drug.


Q: Is Foster effective for treating COPD or only asthma?

Official regulatory documents confirm that Foster is licensed for the regular maintenance treatment of asthma in adults and adolescents. It is also licensed for the symptomatic treatment of severe Chronic Obstructive Pulmonary Disease (COPD) in adult patients, where the use of a combination product is considered appropriate.


Q: Can using Foster make my bones weaker over time?

Long-term or high-dose use of inhaled corticosteroids, the drug class of the Beclometasone component, is associated with a potential risk of systemic effects, including reduced bone mineral density. Regulatory documents note that this may rarely be associated with osteoporosis (weakening of the bones), particularly for patients with existing risk factors.


Q: How does Foster relate to other combination inhalers that use similar ingredients?

Foster is classified as a fixed-dose combination (FDC) product. This means it combines two different types of medicine (an Inhaled Corticosteroid and a Long-Acting beta2-Agonist) into a single inhaler device. This ICS/LABA classification is a standard therapeutic approach used in the continuous management of chronic respiratory conditions.


Q: Are there specific instructions for cleaning and caring for the inhaler device?

Official instructions advise that the inhaler device may be cleaned with a dry cloth or tissue if needed. However, it is explicitly instructed not to clean the inhaler with water or other liquids, as it is essential to keep the device dry to ensure proper function and dosage delivery.


Q: Does using Foster make me more susceptible to infections?

For patients with Chronic Obstructive Pulmonary Disease (COPD), the corticosteroid component is associated with an increased incidence of pneumonia. Additionally, caution is generally advised for patients who have existing infections in the airways (such as fungal, viral, or tuberculosis), as steroids can potentially influence the body's immune response.


Q: What happens if I use the inhaler when it is almost empty?

Official device instructions advise the patient to discard the inhaler when the dose counter shows '0'. The purpose of this instruction is to ensure that the patient stops using the inhaler before the remaining doses may deliver an inaccurate or insufficient amount of the medicine.


Q: How do doctors monitor the effectiveness of Foster treatment?

Regulatory guidance states that the patient should be regularly reassessed by a doctor to ensure that the dosage remains appropriate. The effectiveness of the treatment is typically monitored through a clinical assessment of the patient’s symptoms and through professional measures of lung function.


Q: Does research indicate any differences in effectiveness based on age?

Official regulatory documents indicate that there is no need to adjust the dose specifically for elderly patients (typically those aged 65 and over). For adolescents (12-17 years), the same dosage as adults is generally used to manage asthma, indicating consistency in expected effectiveness across the approved adult and adolescent populations.


Q: Can using Foster affect my sleeping patterns?

Adverse reaction listings include effects such as restlessness and anxiety, which can potentially affect sleeping patterns. These are generally classified as uncommon side effects and are related to the Formoterol component, which has a stimulating effect.


Q: Does using Foster make me more likely to get thrush in my mouth?

Oral candidiasis (thrush in the mouth), which is caused by a fungus, is listed as a Common adverse reaction. This is related to the local effect of the Beclometasone (steroid) component. Official administration instructions advise rinsing the mouth with water and spitting it out after use to help reduce this risk.


Q: Can I use Foster when I am pregnant or breastfeeding?

Official documentation notes that Foster is not recommended for use during pregnancy or lactation unless the expected benefit to the patient is judged to outweigh any potential risk to the child. This is because there is limited or insufficient clinical data to definitively establish the medicine's safety in these specific populations.


Q: What if I travel to a high-altitude place; does that change how Foster works?

Published studies on pressurized metered-dose inhalers (pMDIs) generally indicate that the dose delivered by the device is not significantly affected by changes in altitude. The performance of the inhaler tends to remain consistent across different altitudes.


Q: What does the research say about stopping Foster and how to do it safely?

Regulatory documents state that treatment should not be stopped abruptly, and any decision to stop or change the dosage must be made under medical supervision. The safety caution is because sudden discontinuation may lead to a loss of control over the chronic condition, or rarely, symptoms related to adrenal insufficiency.


Q: Can Foster cause changes to my voice or throat irritation?

Yes. Adverse reaction listings classify dysphonia (a hoarse voice) and pharyngitis (sore throat or throat irritation) as Common side effects that have been reported with the use of the medicine.

How should Foster be stored and disposed of?

How to Store and Dispose of Foster?

Official regulatory documentation outlines specific requirements for storing and disposing of the Foster pressurized metered-dose inhaler (pMDI).

Storage Conditions and Stability

Condition Regulatory Requirement
Temperature (Unopened) Store in a refrigerator (2 C to 8 C).
Temperature (In-Use) Do not store at a temperature above 25 C or 30 C (depending on region).
Stability (In-Use) Discard after 3 months from dispensing or first use, or when the dose counter shows 0.
Protection Keep this medicine out of the sight and reach of children.

Handling and Disposal Rules

Due to the pressurized nature of the canister, official rules prohibit exposure to temperatures higher than 50 C and mandate that the canister must not be pierced or thrown into a fire or incinerator. The inhaler must not be disposed of in household waste or wastewater. Unused or expired products should be returned to a pharmacist for proper environmental disposal, as required by regulation.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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