Flogen

Carefully consider the potential benefits and risks of Flogen, Flogen, ANAPROX, ANAPROX DS or Flogen Suspension and other treatment options before deciding to use Flogen, Flogen, ANAPROX, ANAPROX DS or Flogen Suspension. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals.

Flogen as Flogen, Flogen, ANAPROX, ANAPROX DS or Flogen Suspension is indicated:

• For the relief of the signs and symptoms of rheumatoid arthritis
• For the relief of the signs and symptoms of osteoarthritis
• For the relief of the signs and symptoms of ankylosing spondylitis
• For the relief of the signs and symptoms of juvenile arthritis

Flogen as Flogen Suspension is recommended for juvenile rheumatoid arthritis in order to obtain the maximum dosage flexibility based on the patient's weight.

Flogen as Flogen and Flogen Suspension is also indicated:

• For relief of the signs and symptoms of tendonitis
• For relief of the signs and symptoms of bursitis
• For relief of the signs and symptoms of acute gout
• For the management of pain
• For the management of primary dysmenorrhea

Flogen is not recommended for initial treatment of acute pain because the absorption of Flogen is delayed compared to absorption from other Flogen-containing products.

Flogen is a nonsteroidal anti-inflammatory drug (NSAID). Flogen works by reducing hormones that cause inflammation and pain in the body.

Flogen is used to treat pain or inflammation caused by conditions such as arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps.

The delayed-release or extended-release tablets are slower-acting forms of Flogen that are used only for treating chronic conditions such as arthritis or ankylosing spondylitis. These forms of Flogen will not work fast enough to treat acute pain.

Flogen may also be used for purposes not listed in this medication guide.

Usual Adult Dose for Ankylosing Spondylitis:

Initial: 250 mg to 500 mg (Flogen) or 275 mg to 550 mg (Flogen) orally twice a day. The initial dose for Flogen controlled-release is two 375 mg tablets (750 mg) orally once a day, one 750 mg tablet orally once a day, or two 500 mg tablets (1000 mg) orally once a day.

Maintenance: May be increased to a daily maximum of 1500 mg (Flogen) or 1650 mg (Flogen) in 2 divided doses, for limited periods up to 6 months. In patients who tolerate lower doses well, the dose of Flogen controlled-release may be increased to two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) orally once a day for limited periods.

Usual Adult Dose for Osteoarthritis:

Initial: 250 mg to 500 mg (Flogen) or 275 mg to 550 mg (Flogen) orally twice a day. The initial dose for Flogen controlled-release is two 375 mg tablets (750 mg) orally once a day, one 750 mg tablet orally once a day, or two 500 mg tablets (1000 mg) orally once a day.

Maintenance: May be increased to a daily maximum of 1500 mg (Flogen) or 1650 mg (Flogen) in 2 divided doses, for limited periods up to 6 months. In patients who tolerate lower doses well, the dose of Flogen controlled-release may be increased to two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) orally once a day for limited periods.

Usual Adult Dose for Rheumatoid Arthritis:

Initial: 250 mg to 500 mg (Flogen) or 275 mg to 550 mg (Flogen) orally twice a day. The initial dose for Flogen controlled-release is two 375 mg tablets (750 mg) orally once a day, one 750 mg tablet orally once a day, or two 500 mg tablets (1000 mg) orally once a day.

Maintenance: May be increased to a daily maximum of 1500 mg (Flogen) or 1650 mg (Flogen) in 2 divided doses, for limited periods up to 6 months. In patients who tolerate lower doses well, the dose of Flogen controlled-release may be increased to two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) orally once a day for limited periods.

Usual Adult Dose for Acute Gout:

750 mg (Flogen) or 825 mg (Flogen) orally one time, followed by 250 mg (Flogen) or 275 mg (Flogen) every 8 hours until the gouty attack has resolved, usually 2 to 3 days. The recommended dose of Flogen controlled-release is two to three 500 mg tablets (1000 to 1500 mg) orally on the first day, followed by two 500 mg tablets (1000 mg) orally daily until the attack has subsided.

Usual Adult Dose for Bursitis:

550 mg Flogen orally once, followed by 550 mg Flogen every 12 hours, or 275 mg (Flogen)/250 mg (Flogen) every 6 to 8 hours as needed. Titrate to a maximum daily dose of 1100 mg Flogen or 1000 mg Flogen. The recommended initial dose of Flogen controlled-release is two 500 mg tablets (1000 mg) orally once a day. For patients requiring greater analgesic benefit, two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) may be used for a limited period. Thereafter, the total daily dose should not exceed two 500 mg tablets (1000 mg).

Usual Adult Dose for Tendonitis:

550 mg Flogen orally once, followed by 550 mg Flogen every 12 hours, or 275 mg (Flogen)/250 mg (Flogen) every 6 to 8 hours as needed. Titrate to a maximum daily dose of 1100 mg Flogen or 1000 mg Flogen. The recommended initial dose of Flogen controlled-release is two 500 mg tablets (1000 mg) orally once a day. For patients requiring greater analgesic benefit, two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) may be used for a limited period. Thereafter, the total daily dose should not exceed two 500 mg tablets (1000 mg).

Usual Adult Dose for Dysmenorrhea:

550 mg Flogen orally once, followed by 550 mg Flogen every 12 hours, or 275 mg (Flogen)/250 mg (Flogen) every 6 to 8 hours as needed. Titrate to a maximum daily dose of 1100 mg Flogen or 1000 mg Flogen.

Over-the-counter preparation: Flogen 220 mg orally every 8 hours as needed. Do not exceed 2 caplets in any 8- to 12-hour period.

The recommended initial dose of Flogen controlled-release is two 500 mg tablets (1000 mg) orally once a day. For patients requiring greater analgesic benefit, two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) may be used for a limited period. Thereafter, the total daily dose should not exceed two 500 mg tablets (1000 mg).

Usual Adult Dose for Pain:

550 mg Flogen orally once, followed by 550 mg Flogen every 12 hours, or 275 mg (Flogen)/250 mg (Flogen) every 6 to 8 hours as needed. Titrate to a maximum daily dose of 1100 mg Flogen or 1000 mg Flogen.

Over-the-counter preparation: Flogen 220 mg orally every 8 hours as needed. Do not exceed 2 caplets in any 8- to 12-hour period.

The recommended initial dose of Flogen controlled-release is two 500 mg tablets (1000 mg) orally once a day. For patients requiring greater analgesic benefit, two 750 mg tablets (1500 mg) or three 500 mg tablets (1500 mg) may be used for a limited period. Thereafter, the total daily dose should not exceed two 500 mg tablets (1000 mg).

Usual Geriatric Dose for Pain:

Over-the-counter preparation - 220 mg (Flogen) orally every 12 hours or 250 mg (Flogen) orally every 8 hours as needed.

Usual Pediatric Dose for Fever:

Dosage guidelines are based on Flogen:

Greater than 2 years: 2.5 to 10 mg/kg/dose. Maximum daily dose is 10 mg/kg, given every 8 to 12 hours.

Usual Pediatric Dose for Pain:

Dosage guidelines are based on Flogen:

Greater than 2 years: 2.5 to 10 mg/kg/dose. Maximum daily dose is 10 mg/kg, given every 8 to 12 hours.

Usual Pediatric Dose for Juvenile Rheumatoid Arthritis:

Dosage guidelines are based on Flogen:

Greater than or equal to 2 years: 5 mg/kg orally twice a day. Maximum dose: 1000 mg/day.