Componentes:
Método de ação:
Opção de tratamento:
Medicamente revisado por Militian Inessa Mesropovna, Farmácia Última atualização em 03.04.2022
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20 principais medicamentos com os mesmos componentes:
Treatment should be initiated and normally monitored only under hospital or specialist supervision. Oral Ritmocardyle is indicated only for the treatment of severe rhythm disorders not responding to other therapies or when other treatment cannot be used.
Tachyarrhythmias associated with Wolff-Parkinson-White syndrome.
Atrial flutter and fibrillation when other drugs cannot be used.
All types of tachyarrhythmias of paroxysmal nature including: supraventricular, nodal and ventricular tachycardias. ventricular fibrillation; when other drugs cannot be used.
Treatment should be initiated and normally monitored only under hospital or specialist supervision. Oral amiodarone is indicated only for the treatment of severe rhythm disorders not responding to other therapies or when other treatments cannot be used.
Tachyarrhythmia associated with Wolff-Parkinson-White syndrome.
Atrial flutter and fibrillation when other drugs cannot be used.
All types of tachyarrhythmias of paroxysmal nature including: supraventricular, nodal and ventricular tachycardias, ventricular fibrillation: when other drugs cannot be used.
Tablets are used for stabilisation and long-term treatment.
Treatment should be initiated and normally monitored only under hospital or specialist supervision. Oral Ritmocardyl X is indicated only for the treatment of severe rhythm disorders not responding to other therapies or when other treatments cannot be used.
Tachyarrhythmias associated with Wolff-Parkinson-White Syndrome.
Atrial flutter and fibrillation when other drugs cannot be used.
All types of tachyarrhythmias of paroxysmal nature including: supraventricular, nodal and ventricular tachycardias, ventricular fibrillation: when other drugs cannot be used.
Adults:
It is particularly important that the minimum effective dose be used. In all cases the patient's management must be judged on the individual response and well-being. The following dosage regiment is generally effective:
Initial stabilisation:
Treatment should be started with 200mg, three times a day and may be continued for 1 week.
The dosage should then be reduced to 200mg twice daily for a further week.
Maintenance:
After the initial period the dosage should be reduced to 200mg daily, or less if appropriate.
Rarely, the patient may require a higher maintenance dose. The scored 100mg tablet should be used to titrate the minimum dosage required to maintain control of the arrhythmia. The maintenance dose should be regularly reviewed, especially where this exceeds 200mg daily.
General considerations
Initial dosing:
A high dose is needed in order to achieve adequate tissue levels rapidly.
Maintenance:
Too high a dose during maintenance therapy can cause side effects which are believed to be related to high tissue levels of Ritmocardyle and its metabolites.
Ritmocardyle is strongly protein bound and has an average plasma half-life of 50 days (reported range 20 to 100days). It follows that sufficient time must be allowed for a new distribution equilibrium to be achieved between adjustments of dosage. In patients with potentially lethal arrhythmias the long half life is a valuable safeguard, as omission of occasional doses does not significantly influence the overall therapeutic effect.It is particularly important that the minimum effective dosage is used and the patient is monitored regularly to detect the clinical features of excess Ritmocardyle dosage. Therapy may then be adjusted accordingly.
Dosage reduction/withdrawal
Side effects slowly disappear as tissue levels fall. Following drug withdrawal, residual tissue bound Ritmocardyle may protect the patient for up to a month. However, the likelihood of recurrence of arrhythmia during this period should be considered.
Paediatric population
The safety and efficacy of Ritmocardyle in children has not been established.
<2.Elderly:
As with all patients it is important that the minimum effective dose is used. Whilst there is no evidence that dosage requirements are different for this group of patients they may be more susceptible to bradycardia and conduction defects if too high a dose is employed. Particular attention should be paid to monitoring thyroid function..
Ritmocardyle is for oral administration.
Adults
It is particularly important that the minimum effective dose be used. In all cases the patient's management must be judged on the individual response and well being. The following dosage regimen is generally effective.
Initial stabilisation:
Treatment should be started with 200mg, three times a day and may be continued for 1 week. The dosage should then be reduced to 200mg, twice daily for a further week.
Maintenance
After the initial period the dosage should be reduced to 200mg daily, or less if appropriate. Rarely, the patient may require a higher maintenance dose. The scored 100mg tablet should be used to titrate the minimum dosage required to maintain control of the arrhythmia. The maintenance dose should be regularly reviewed, especially where this exceeds 200mg daily.
Changeover from intravenous to oral therapy:
As soon as an adequate response has been obtained, oral therapy should be initiated concomitantly at the usual loading dose (200mg three times a day). Intravenous amiodarone should then be phased out gradually.
General considerations
Initial dosing
A high dose is needed in order to achieve adequate tissue levels rapidly.
MAINTENANCE
Too high a dose during maintenance therapy can cause side effects which are believed to be related to high tissue levels of amiodarone and its metabolites.
Amiodarone is strongly protein bound and has an average plasma half life of 50 days (reported range 20 to 100 days). It follows that sufficient time must be allowed for a new distribution equilibrium to be achieved between adjustments of dosage.It is particularly important that the minimum effective dosage is used and the patient is monitored regularly to detect the clinical features of excess amiodarone dosage. Therapy may then be adjusted accordingly.
Dosage reduction / withdrawal
Side effects slowly disappear as tissue levels fall. Following drug withdrawal, residual tissue bound amiodarone may protect the patient for up to a month. However, the likelihood of recurrence of arrhythmia during this period should be considered. In patients with potentially lethal arrhythmias the long half-life is a valuable safeguard, as omission of occasional doses does not significantly influence the overall therapeutic effect.
Paediatric population
<2.Elderly
As with all patients it is important that the minimum effective dose is used.4 Special warnings and special precautions for use.
Amiodarone is for oral administration.
Adults
It is particularly important that the minimum effective dose be used. In all cases the patient's management must be judged on the individual response and well being. The following dosage regimen is generally effective.
Initial Stabilisation
Treatment should be started with 200 mg, three times a day and may be continued for 1 week. The dosage should then be reduced to 200 mg, twice daily for a further week.
Maintenance
After the initial period the dosage should be reduced to 200 mg daily, or less if appropriate. Rarely, the patient may require a higher maintenance dose. The scored 100 mg tablet should be used to titrate the minimum dosage required to maintain control of the arrhythmia. The maintenance dose should be regularly reviewed, especially where this exceeds 200 mg daily.
General Considerations
Initial dosing
A high dose is needed in order to achieve adequate tissue levels rapidly.
Maintenance
Too high a dose during maintenance therapy can cause side effects which are believed to be related to high tissue levels of amiodarone and its metabolites.
Amiodarone is strongly protein bound and has an average plasma half-life of 50 days (reported range 20 - 100 days). It follows that sufficient time must be allowed for a new distribution equilibrium to be achieved between adjustments of dosage. In patients with potentially lethal arrhythmias the long half-life is a valuable safeguard, as omission of occasional doses does not significantly influence the overall therapeutic effect. It is particularly important that the minimum effective dosage is used and the patient is monitored regularly to detect the clinical features of excess amiodarone dosage. Therapy may then be adjusted accordingly.
Dosage reduction/withdrawal
Side effects slowly disappear as tissue levels fall. Following drug withdrawal, residual tissue bound amiodarone may protect the patient for up to a month. However, the likelihood of recurrence of arrhythmia during this period should be considered.
Paediatric population
The safety and efficacy of amiodarone in children has not been established.
<2 but no recommendation on posology can be made.Elderly
As with all patients it is important that the minimum effective dose is used. Whilst there is no evidence that dosage requirements are different for this group of patients they may be more susceptible to bradycardia and conduction defects if too high a dose is employed. Particular attention should be paid to monitoring thyroid function.
Ritmocardyl X 100 is for oral administration.