Toff DC

Toff DC is an antihistamine/nasal decongestant/cough suppressant indicated for the temporary relief of nasal congestion, cough, runny nose, sneezing, itching of the nose or throat, and itchy, watery eyes due to the common cold, hay fever, inhaled irritants, or other upper respiratory allergies.

Chlorpheniramine (Toff DC) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan (Toff DC) is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine (Toff DC) is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Chlorpheniramine (Toff DC), Dextromethorphan (Toff DC), and Phenylephrine (Toff DC) is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlorpheniramine (Toff DC), Dextromethorphan (Toff DC), and Phenylephrine (Toff DC) may also be used for purposes not listed in this medication guide.

Usual Adult Dose for Cough and Nasal Congestion:

Toff DC 1 mg-5 mg-2.5 mg/5 mL oral liquid

20 mL orally every 4 hours not to exceed 6 doses daily.

Toff DC 2 mg-10 mg-5 mg/5 mL oral liquid:

10 mL orally every 4 hours not to exceed 6 doses daily.

Toff DC 2 mg-30 mg-20 mg oral tablet, extended release:

1 to 2 tablets orally every 12 hours not to exceed 4 tablets daily.

Toff DC 4 mg-15 mg-12.5 mg/5 mL oral syrup:

5 mL orally every 4 to 6 hours not to exceed 30 mL daily.

Toff DC 8 mg-30 mg-20 mg oral tablet, extended release:

1 to 2 tablets orally every 12 hours not to exceed 3 tablets daily.

Usual Pediatric Dose for Cough and Nasal Congestion:

Toff DC 0.75 mg-2.75 mg-1.75 mg/mL oral drops:

2 to 5 years: 1 mL orally every 4 to 6 hours not to exceed 4 doses daily.

6 to 12 years: 2 mL orally every 4 to 6 hours not to exceed 4 doses daily.

Toff DC 1 mg-3 mg-1.5 mg/mL oral liquid:

2 to 5 years: 1 mL orally every 4 to 6 hours not to exceed 4 doses daily.

6 to 12 years: 2 mL orally every 4 to 6 hours not to exceed 4 doses daily.

Toff DC 1 mg-3 mg-2 mg/mL oral drops:

2 to 5 years: 1 mL orally every 4 to 6 hours.

6 to 11 yrs: 2 mL orally every 4 to 6 hours.

Toff DC 1 mg-3 mg-3.5 mg/mL oral liquid:

6 to 11 months: 0.75 mL orally 4 times daily.

1 to 2 years: 1 mL orally 4 times daily.

Toff DC 1 mg-5 mg-2.5 mg/5 mL oral liquid

6 to 11 years: 10 mL orally every 4 hours not to exceed 6 doses daily.

12 years or older: 20 mL orally every 4 hours not to exceed 6 doses daily.

Toff DC 2 mg-10 mg-5 mg/5 mL oral liquid:

6 to 11 years: 5 mL orally every 4 hours not to exceed 6 doses daily.

12 years or older: 10 mL orally every 4 hours not to exceed 6 doses daily.

Toff DC 2 mg-30 mg-20 mg oral tablet, extended release:

6 to 11 years: 1 tablet orally every 12 hours not to exceed 2 tablets daily.

12 years or older: 1 to 2 tablets orally every 12 hours not to exceed 4 tablets daily.

Toff DC 4 mg-15 mg-12.5 mg/5 mL oral syrup:

2 to 5 years: 1.25 mL orally every 4 to 6 hours not to exceed 7.5 mL daily.

6 to 11 yrs: 2.5 mL orally every 4 to 6 hours not to exceed 15 mL daily.

12 years or older: 5 mL orally every 4 to 6 hours not to exceed 30 mL daily.

Toff DC 8 mg-30 mg-20 mg oral tablet, extended release:

12 years or older: 1 to 2 tablets orally every 12 hours not to exceed 3 tablets daily.

See also:
What is the most important information I should know about Toff DC?

Toff DC is contraindicated in patients with hypersensitivity or idiosyncrasy to any of its ingredients, patients taking monoamine oxidase (MAO) inhibitors or for two weeks after stopping the MAOI drug, patients with narrow-angle glaucoma, severe coronary artery disease, urinary retention, peptic ulcer, severe hypertension, patients with breathing problems such as emphysema or chronic bronchitis, or nursing mothers.

Use Toff DC drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Toff DC drops by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Use the dropper that comes with Toff DC drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you miss a dose of Toff DC drops and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Toff DC drops.

Use: Labeled Indications

Cough and upper respiratory symptoms: Temporary relief of symptoms (runny nose, sneezing, itchy nose or throat, itchy/watery eyes, cough due to minor throat and bronchial irritation, nasal congestion, nasal passages swelling) associated with the common cold, hay fever (allergic rhinitis), or other upper respiratory allergies.

See also:
What other drugs will affect Toff DC?

If you are taking this medication under your doctor's direction, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking isocarboxazid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, or tranylcypromine during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication.

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication. Avoid taking MAO inhibitors within 2 weeks of starting or stopping this medication.

Before using this product, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), antispasmodics (e.g., atropine, belladonna alkaloids), beta blockers (e.g., metoprolol, atenolol), drugs for Parkinson's disease (e.g., anticholinergics such as benztropine, trihexyphenidyl), guanethidine, certain inhaled anesthetics (e.g., halothane), methyldopa, reserpine, scopolamine, tricyclic antidepressants (e.g., amitriptyline, desipramine).

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone).

Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could affect your heart rate/blood pressure or cause drowsiness. Ask your pharmacist about the safe use of those products.

This medication may interfere with certain medical/laboratory tests (including brain scan for Parkinson's disease), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

See also:
What are the possible side effects of Toff DC?

Drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or dry mouth/nose/throat may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute. This medication can dry up and thicken mucus in your lungs, making it more difficult to breathe and clear your lungs. To help prevent this effect, drink plenty of fluids unless otherwise directed by your doctor.

If your doctor has prescribed this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: mental/mood changes (e.g., confusion, hallucinations), ringing in the ears, shaking (tremors), trouble urinating, weakness.

Tell your doctor right away if any of these rare but very serious side effects occur: easy bruising/bleeding, fast/slow/irregular heartbeat, seizure.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.