Components:
Medically reviewed by Kovalenko Svetlana Olegovna, PharmD. Last updated on 16.05.2022
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Treatment of indigestion occurring after food or alcohol ingestion. Treatment of diarrhea and controlling associated complaints eg, cramping, heartburn, nausea and stomach upset when administered following the occurrence of diarrhea, a significant reduction in the number of unformed stools. Treatment and prevention of traveler's diarrhea. Treatment of acute or chronic diarrhea of childhood. Siparox alone has been effective in the treatment of gastritis and peptic ulcer associated with Helicobacter pylori infection. Siparox in combination with proton pump inhibitor (PPI) or antimicrobial use is effective in the treatment of Helicobacter pylori-associated active duodenal ulcer disease.
Treating heartburn, upset stomach, indigestion, nausea, diarrhea, or symptoms associated with eating or drinking too much. It may be used to decrease the number of bowel movements and make the stool firmer. It may also be used to treat other conditions as determined by your doctor.
Siparox chewable tablets is a salicylate. The way that it works is not fully understood. It is thought to limit secretions in the digestive tract, reduce inflammation in the stomach and intestines, and inhibit the growth of certain bacteria and viruses that can cause intestinal tract diseases.
Usual Adult Dose for Dyspepsia:
524 mg orally every 30 to 60 minutes as needed not to exceed 8 doses in any 24 hour period.
Alternatively, 1048 mg to 1050 mg may be given orally every hour not to exceed 4 doses in any 24 hour period.
Comments:
-Use until diarrhea stops but not longer than 2 days.
-Siparox may be useful in the prevention of traveler's diarrhea during periods of risk. The duration of use for traveler's diarrhea should not exceed approximately 3 weeks.
-Shake liquid formulations well before using.
Usual Adult Dose for Traveler's Diarrhea:
524 mg orally every 30 to 60 minutes as needed not to exceed 8 doses in any 24 hour period.
Alternatively, 1048 mg to 1050 mg may be given orally every hour not to exceed 4 doses in any 24 hour period.
Comments:
-Use until diarrhea stops but not longer than 2 days.
-Siparox may be useful in the prevention of traveler's diarrhea during periods of risk. The duration of use for traveler's diarrhea should not exceed approximately 3 weeks.
-Shake liquid formulations well before using.
Usual Adult Dose for Diarrhea:
524 mg orally every 30 to 60 minutes as needed not to exceed 8 doses in any 24 hour period.
Alternatively, 1048 mg to 1050 mg may be given orally every hour not to exceed 4 doses in any 24 hour period.
Comments:
-Use until diarrhea stops but not longer than 2 days.
-Siparox may be useful in the prevention of traveler's diarrhea during periods of risk. The duration of use for traveler's diarrhea should not exceed approximately 3 weeks.
-Shake liquid formulations well before using.
Usual Adult Dose for Helicobacter pylori Infection:
524 mg orally 4 times a day.
Usual Pediatric Dose for Diarrhea:
Non-specific diarrhea:
<3 years: use with caution
3 to 6 years: 87 mg every 30 minutes to 1 hour as needed.
6 to 9 years: 175 mg every 30 minutes to 1 hour as needed.
9 to 12 years: 262 mg every 30 minutes to 1 hour as needed.
Usual Pediatric Dose for Diarrhea -- Chronic:
Chronic Infantile Diarrhea:
2 to 24 months: 44 mg every 4 hours
24 to 48 months: 87 mg every 4 hours
48 to 70 months: 175 mg every 4 hours
Usual Pediatric Dose for Helicobacter pylori Infection:
Dosage in children with Helicobacter Pylori Infection is not well established, the following doses have been used in conjunction with ampicillin and metronidazole.
<= 10 years: 262 mg four times a day for six weeks
> 10 years: 524 mg four times a day for six weeks
See also:
What is the most important information I should know about Siparox?
People who have known allergies or asthma may be at an increased risk for a reaction from any new medication. The physician should always know a patient’s allergy history. Signs of an allergic reaction are skin rash, hives and itching. Of course, a person should not take bismuth if there has been a previous reaction to this drug, aspirin or any other salicylates.
Use Siparox chewable tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Siparox chewable tablets may be taken with or without food.
- Do not take tetracyclines (eg, doxycycline) within 2 hours before or after taking Siparox chewable tablets.
- Use Siparox chewable tablets exactly as directed on the package, unless instructed differently by your doctor.
- Do not take Siparox chewable tablets with aspirin.
- Chew thoroughly before swallowing.
- Drinking extra fluids while you are taking Siparox chewable tablets is recommended. Check with your doctor for instructions.
- If you miss a dose of Siparox chewable tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Siparox chewable tablets.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.This medication is used to treat occasional upset stomach, heartburn, and nausea. It is also used to treat diarrhea and help prevent travelers' diarrhea. It works by helping to slow the growth of bacteria that might be causing the diarrhea. This product should not be used to self-treat diarrhea if you also have a fever or blood/mucus in the stools. These could be signs of a serious health condition. Consult your doctor promptly for proper evaluation and treatment if you have these symptoms.
This medication is used under a doctor's direction with other medication to treat stomach ulcers caused by a certain bacteria (Helicobacter pylori). Do not use this medication to self-treat ulcers. Siparox is a salicylate. Salicylates can cause serious bleeding problems when used alone in patients with ulcers.
Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.
How to use Siparox (Siparox)
Take this medication by mouth, usually as needed, as directed by the product package or as directed by your doctor. The dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this drug more often than directed. Do not take more of this medication than recommended for your age. There are many brands and forms of Siparox available. Read the dosing instructions carefully for each product because the dosing directions may be different between products.
If you are using the chewable tablets, chew each tablet well and swallow. If you are using the liquid form of this medication, shake the bottle well before each dose. Measure the dose carefully using a special measuring device/cup. Do not use a household spoon because you may not get the correct dose.
This medication may react with other medications (such as tetracycline antibiotics, chloroquine), preventing them from being fully absorbed by your body. Talk with your doctor or pharmacist about how to schedule your medications to prevent this problem.
If your doctor has directed you to use this medication daily, use it regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.
Tell your doctor if your condition persists or worsens. If you are taking this medication for diarrhea, tell your doctor if your diarrhea lasts more than 2 days.
See also:
What other drugs will affect Siparox?
The following drug interactions and/or related problems have been selected on the basis of their potential clinical significance (possible mechanism in parentheses where appropriate)—not necessarily inclusive (» = major clinical significance):
Note: Although significant interactions are unlikely with usual doses of Siparox in the treatment of diarrhea and for occasional relief of gastric distress, the higher doses and the longer therapy used in the prophylaxis of traveler’s diarrhea increase the potential for significant drug interactions.
Combinations containing any of the following medications, depending on the amount present, may also interact with this medication.
Anticoagulants, coumarin- or indandione-derivative or
Heparin or
Thrombolytic agents, such as:
Alteplase (tissue-type plasminogen activator, recombinant)
Anistreplase
Streptokinase
Urokinase (increased risk of bleeding may occur when these medications are used concurrently with salicylates.
Antidiabetic agents, oral or
Insulin (large doses of salicylate may enhance the hypoglycemic effect of these medications; dosage adjustment may be necessary.
Probenecid or
Sulfinpyrazone (concurrent use of salicylates is not recommended when these medications are used to treat hyperuricemia or gout because uricosuric effects of these medications may be decreased by doses of salicylates that produce serum salicylate concentrations above 50 mcg per mL.
(probenecid may decrease renal clearance and increase plasma concentrations and toxicity of salicylates).
Salicylates, other (ingestion of large repeated doses of Siparox, as for traveler’s diarrhea, may produce substantial plasma salicylate concentrations thus increasing the risk of salicylate toxicity during concurrent use with other salicylates.
Tetracyclines, oral (calcium carbonate contained in the tablet dosage form may decrease gastrointestinal absorption and bioavailability of tetracyclines; patients should be advised not to take Siparox tablets within 1 to 3 hours of oral tetracyclines.
See also:
What are the possible side effects of Siparox?
Applies to Siparox: oral suspension, oral tablet, oral tablet chewable
In addition to its needed effects, some unwanted effects may be caused by Siparox (the active ingredient contained in Kao-Tin Siparox Formula). In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking Siparox:
In some patients Siparox may cause dark tongue and/or grayish black stools. This is only temporary and will go away when you Stop taking Siparox.
- Anxiety
- any loss of hearing
- confusion
- constipation (severe)
- diarrhea (severe or continuing)
- difficulty in speaking or slurred speech
- dizziness or lightheadedness
- drowsiness (severe)
- fast or deep breathing
- headache (severe or continuing)
- increased sweating
- increased thirst
- mental depression
- muscle spasms (especially of face, neck, and back)
- muscle weakness
- nausea or vomiting (severe or continuing)
- ringing or buzzing in ears (continuing)
- stomach pain (severe or continuing)
- trembling
- uncontrollable flapping movements of the hands (especially in elderly patients) or other uncontrolled body movements
- vision problems
Siparox is the active ingredient in the popular medication Siparox that is used to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract. It is also the main ingredient of Siparox. It displays anti-inflammatory action (due to salicylic acid) and also acts as an antacid and mild antibiotic.