Беконазе

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Беконазе

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Medically reviewed

Laura Arias

Last updated on 22/12/2025

This page provides general, reference-level information compiled from official medical sources. It is not a substitute for professional medical advice, diagnosis, or treatment. For decisions about your health, please consult a qualified healthcare professional.

Overview of Беконазе

Quick Facts

Property Description
Active ingredient Beclometasone Dipropionate
Form Nasal Spray (Aqueous Suspension)
Pharmacological class Glucocorticoid / Corticosteroid
Common use Prophylactic anti-inflammatory action in the nasal passages
Origin Synthetic compound

What is Беконазе and What is its Pharmacological Class?

Беконазе is a pharmaceutical product formulated for Intranasal Administration and is classified pharmacologically as a potent Glucocorticoid that belongs to the broader class of Corticosteroids. The medicine’s core component is Beclometasone Dipropionate, which is a synthetic halogenated steroid diester. Beclometasone is highly effective when delivered topically because it is quickly converted to its active metabolite in the target tissue. This highly localized and low-systemic-absorption approach improves the safety profile compared to older, oral corticosteroid therapies.

Composition: A Single-Ingredient Topical Anti-Inflammatory

This product is a Single-ingredient product, consisting of Beclometasone Dipropionate suspended within an Aqueous Medium. The compound itself functions as an inert prodrug that is rapidly metabolized upon contact with the nasal mucosa, producing the highly active therapeutic agent, Beclometasone 17-monopropionate (17-BMP). When administered intranasally, the medicine primarily works directly on the nasal lining to reduce inflammation. The specialized Nasal Spray delivery ensures the potent Glucocorticoid effect is concentrated precisely where the symptoms originate.

The General Purpose: Targeted Anti-Inflammatory Action

The overall purpose of Беконазе is to deliver a powerful, localized Anti-Inflammatory Effect, serving as Prophylactic Therapy and Maintenance Treatment for chronic nasal issues. By engaging with local immune receptors, the medicine works to suppress the underlying inflammatory cascade. This results in the sustained Reduction of Swelling and fluid production in the nasal lining, a benefit that is paramount in relieving the persistent congestion and irritation associated with conditions like severe seasonal discomfort.

What side effects are possible with Беконазе?

Possible Side Effects and Safety Information

Beclomethasone dipropionate nasal spray (Беконазе) is a corticosteroid, and its safety profile is characterized by common local reactions and, rarely, by systemic effects typical of this class of medication.

Adverse Reactions

Classification Side Effects
Common Nasal discomfort/irritation, dryness of the nose and throat, epistaxis (nosebleeds), sneezing, headache, unpleasant taste/smell.
Rare Immediate hypersensitivity reactions (e.g., angioedema, rash, bronchospasm), nasal septal perforation, glaucoma, cataracts, and increased intraocular pressure.

Safety Considerations

  • Systemic Risk: Although the drug is administered locally, systemic corticosteroid effects, such as hypercorticism or adrenal suppression, may occur. The risk is typically associated with exceeding recommended doses, prolonged use, or individual sensitivity. Patients being transferred from systemic steroids require particular caution.
  • Pediatric Use: Use in children and adolescents may be associated with a reduction in growth velocity. Regular monitoring of height is recommended for children on long-term treatment.
  • Local Infections: Caution is advised in patients with active or quiescent tuberculosis, untreated fungal, bacterial, or systemic viral infections, or ocular herpes simplex. The spray should not be used in the presence of an untreated localized infection involving the nasal mucosa, such as candidiasis (thrush).
  • Ophthalmic: Rare cases of cataracts, glaucoma, and elevated intraocular pressure have been reported. Patients with a history of these conditions or those experiencing visual changes should be monitored by an ophthalmologist.
  • Contraindications: The medicine is contraindicated in patients with known hypersensitivity to the drug or its components.

Overdose and Emergency Response

Overdose and When to Seek Help

Official regulatory information addresses two primary scenarios concerning an overdose of Beclomethasone Dipropionate Nasal Spray (Беконазе): acute accidental over-exposure and chronic high-dose use.

Acute Overdose

A single, excessive exposure to this medication, such as accidental ingestion or excessive short-term use, is unlikely to cause acute, severe toxicity because the medication is poorly absorbed into the body when used nasally. Treatment for such an event is typically limited to medical observation and does not usually require specific intervention.

Chronic Overdose Risks

The primary risk associated with overdose is from the chronic use of doses higher than officially recommended for a prolonged period. This chronic over-exposure can lead to significant systemic effects, including:

  • Hypercorticism: Signs and symptoms resulting from excessive corticosteroid levels.
  • Adrenal Suppression (HPA Axis Suppression): A serious condition where the body's natural production of steroid hormones is suppressed, impacting the Hypothalamic-Pituitary-Adrenal (HPA) axis.

Required Emergency Actions

In cases of suspected chronic overdose or HPA axis suppression, the required medical action is gradual withdrawal or reduction of the medication's dose under the strict supervision of a healthcare professional.

Immediate medical attention should be sought if an individual experiences symptoms of a serious allergic reaction, such as swelling of the face, throat, or tongue, difficulty breathing, or fainting, as these require emergency treatment.

Therapeutic Uses of Беконазе

What Beconase Treats: Main Uses and Benefits

Beconase is a nasal corticosteroid that may help manage symptoms associated with rhinitis. This medicine may be used to address symptoms of both allergic rhinitis (such as hay fever) and nonallergic rhinitis.

It is used to support the management of symptoms in the nasal passages often caused by allergens like pollen, mold, or dust. The medicine may help manage associated symptoms, including sneezing, a runny nose, stuffiness, and nasal itching. For individuals dealing with seasonal allergies or year-round triggers, Beconase is an agent used to support the management of these conditions.

It is intended to provide localized relief, which may help lessen discomfort and support daily function. It may be used to help relieve allergy symptoms such as runny nose, sneezing, and watery/itchy eyes.

Quick Fact: Relief for Runny Nose and Sneezing

The medicine offers localized support for common allergic and nonallergic symptoms, serving as one tool in the management plan for persistent nasal irritation.

Regulatory References

  1. NIH MedlinePlus overview of fluticasone nasal spray

Eligibility and Restrictions for Use

Eligibility Map: Who can and cannot use Беконазе — Official Regulatory Information

Populations for whom use is contraindicated:

  • Use is absolutely contraindicated in patients with known hypersensitivity (allergy) to beclometasone dipropionate or any ingredient in the preparation.

Age-related eligibility rules:

  • The minimum age threshold for use is typically 4 or 6 years of age, depending on the specific product formulation and regional regulatory approval. Safety and efficacy are not established below the lowest approved minimum age. Pediatric patients receiving prolonged treatment are required to undergo routine monitoring of growth velocity.

Condition-specific eligibility rules:

  • The medicine must not be used in patients who have experienced recent nasal surgery, trauma, or nasal ulcers until complete healing has occurred.
  • Use requires caution in the presence of untreated localized nasal infections or systemic infections such as tuberculosis, as well as in patients with a history of glaucoma or cataracts.

Pregnancy and lactation eligibility status (if explicitly documented):

  • Use during pregnancy is generally avoided unless the potential benefit justifies the potential risk to the fetus, as adequate human studies are lacking. Caution must be exercised for nursing mothers as it is unknown if the drug is excreted into human milk.

Connection to the overall eligibility profile: The regulatory profile strictly defines who can and cannot use the medicine by establishing absolute contraindications based on allergy, setting age-based thresholds where safety is established, and imposing conditional restrictions related to the patient’s current tissue health or infection status.

What should I know about interactions with other medicines?

Interactions with other medicines and products

Beclomethasone nasal spray (Beconase) is primarily a locally acting medication, and systemic absorption at recommended doses is generally low. However, drug interactions are still possible, particularly with medications that affect the metabolism of corticosteroids. The nasal spray may also contribute to the total corticosteroid load if the patient is using other steroid products.

It is essential to inform your healthcare provider and pharmacist about all prescription and non-prescription medicines, vitamins, herbal remedies, and supplements you are currently taking or plan to take. They can assess the risk of interaction and determine if a dosage adjustment or closer monitoring is necessary.

Notable Drug Interactions

Type of Interacting Medicine Potential Interaction Recommendation
Other Corticosteroids (e.g., oral tablets, creams, inhalers, drops) Increased risk of systemic corticosteroid side effects, including adrenal suppression. Use together only under close medical supervision; monitor for signs of excessive steroid exposure.
CYP3A4 Inhibitors (e.g., Ritonavir, Cobicistat) These powerful medicines can significantly increase the concentration of beclomethasone in the blood, raising the risk of systemic side effects. Avoid co-administration unless the benefit outweighs the risk, and be closely monitored for steroid side effects.

Using Beconase with other corticosteroids or potent CYP3A4 inhibitors is generally discouraged unless directed by a specialist. The safety and efficacy of complementary or herbal medicines in combination with Beconase have not been fully established, and advice from a healthcare professional should be sought before using them.

Mechanism of Action

Mechanism of Action: How Беконазе Works

Беконазе functions primarily by modulating inflammation at the cellular level within the nasal mucosa. The active metabolite binds with high affinity to the Glucocorticoid Receptor (GR), initiating a process of genomic modulation.

This targeted agonist action alters the cell’s output by promoting the transcription of anti-inflammatory proteins while simultaneously restricting the activity of key pro-inflammatory transcription factors, such as NF-kappaB. This inhibitory process, known as transrepression, prevents the activation of genes responsible for producing numerous inflammatory mediators, including cytokines, chemokines, and leukotrienes.

Limiting the production of these chemical signals suppresses components of the local inflammatory immune response. This biological suppression leads to a reduction of inflammatory effects on the nasal microvasculature. The resulting physiological consequence is a decrease in capillary permeability, which contributes to decreased mucosal edema and reduced glandular hypersecretion.

Dosage and Administration Information

Administration Guidelines

The use of Беконазе (Beclometasone Dipropionate Nasal Spray) is based on specific instructions concerning its administration route, dosage, and frequency. This medicine is for Intranasal administration, designed for localized delivery to the nasal lining.


Administration Scope

Feature Parameters of Use
Route of administration Intranasal administration.
Dosing schedule (Adults) Initial/Standard Dose: A common starting regimen is 400 micrograms (mcg) total daily dose. Maintenance Dose: The dose is reduced to the minimum effective dose, typically 200 mcg daily.
Frequency pattern The standard schedule is Twice Daily (BID) (e.g., two sprays in each nostril twice daily), though some formulations are used Once Daily (QD).
Age-group administration Children over six years: Often follow the adult initial (400 mcg/day) and maintenance (200 mcg/day) schedule. Older Adults: The dosage follows the adult recommendation.

Procedural Conditions and Use Protocol

Prior to initial use, the nasal spray device requires a priming procedure (e.g., four to six actuations) and is reprimed if unused for a specified period (e.g., seven days) to ensure proper dose delivery. The administration protocol is structured around a continuous, scheduled regimen, as the medicine is used regularly and therapeutic benefit may take several days to be fully established. The goal of the protocol is to transition from the initial dose to the minimum effective maintenance dose once control is achieved, which is the principle for the medicine's long-term use.

Recent Clinical Evidence

Research evidence / Overview of studies for Беконазе (Beclometasone Dipropionate)


Evidence from Randomized Trials for Allergic Rhinitis

Research has primarily used Randomized Controlled Trials (RCTs) to examine conditions such as seasonal and perennial allergic rhinitis (SAR and PAR). Studies in this area employ short-term (up to 6 weeks) and intermediate-term (up to 12 weeks) trials. These trials included a comparison arm, such as a placebo, and were applied in studies examining patient-reported experiences. Researchers monitored patient-reported outcomes describing perceived discomfort related to physical discomfort, such as Total Nasal Symptom Scores (TNSS), which combine measurements for congestion, sneezing, itching, and a runny nose.

Studies reported measurement patterns in Total Nasal Symptom Scores (TNSS) within the groups being observed. Research has explored outcomes in a variety of groups, including Adults, Adolescents, and Children aged 4 and older, as part of the evidence base for this medicine. While research highlights changes measured during the study period, comparative evidence against other, similar products may be mixed or limited.


Studies on Non-Allergic Conditions and Other Uses

Research has also examined the medicine in conditions presenting with cycles of stability and flare-ups that are not triggered by typical allergens, known as non-allergic (vasomotor) rhinitis. These studies monitored patient-reported outcomes describing perceived discomfort over defined time intervals. Evidence for non-allergic conditions is often cited in systematic reviews as having a lower certainty level compared to allergic rhinitis.

Research was studied for post-surgical observation following the removal of nasal polyps, a condition marked by functional limitations. Trials reported data on the recurrence rate of polyps and outcomes related to overall symptoms. These studies often require longer observation periods than those for allergic rhinitis, and a full therapeutic assessment may take several weeks or more of use.


What the Research Landscape Still Leaves Uncertain

The research base for allergic rhinitis, while substantial in volume, still presents areas of uncertainty and limitation. Certainty remains low regarding sustained changes in symptoms for the non-allergic rhinitis population, and few data are available for extended-duration effects past three months in this group. Furthermore, while the evidence base for children exists, the follow-up durations were limited in many of the core trials, meaning long-term effects are not fully established in this population. Results apply only to the populations studied, and comparative evidence against all other similar nasal sprays is often lacking or mixed across different studies.

Frequently Asked Questions (FAQ)

Common questions about Беконазе (FAQ)


Q: How long does it usually take before I notice the effects of Беконазе?

Initial relief may begin relatively quickly after starting treatment. However, official product information indicates that the full, maximum therapeutic benefit may require continuous, regular use for a period, typically ranging from a few days up to two weeks.


Q: Can Беконазе be used for allergies that aren't just seasonal?

Yes, official indications state that this medicine is used for the relief of nasal symptoms associated with both seasonal allergic rhinitis (allergies that occur during specific seasons) and perennial allergic rhinitis (year-round allergies).


Q: Is it possible for Беконазе to make my nose bleed?

Yes, regulatory safety documents list epistaxis, which is the medical term for nosebleeds, as a common adverse reaction associated with the use of this nasal spray. Nasal discomfort and irritation are also common local effects.


Q: Is it true that Беконазе can affect eye pressure or cause cataracts?

Rare cases of increased intraocular pressure (eye pressure), glaucoma, and cataracts have been reported with the use of intranasal corticosteroids. For this reason, official warnings describe the need for monitoring for visual changes, particularly if a patient has a history of these conditions.


Q: Can I use Беконазе if I'm pregnant or breastfeeding?

Regulatory information indicates that use during pregnancy is generally avoided unless the potential benefit justifies the potential risk, as human studies are lacking. For nursing mothers, caution is advised because it is not known if the medicine passes into human milk.


Q: Can I use Беконазе with other allergy treatments like antihistamine tablets?

Due to the medicine's localized action and low systemic absorption, major interaction warnings are typically focused on other steroid products rather than non-corticosteroid allergy treatments. It is standard practice to inform a healthcare provider about all medicines being taken.


Q: Has there been research on Беконазе's use in chronic sinusitis?

While the primary approved indication is allergic rhinitis, research has been conducted that examines the use of beclomethasone dipropionate in managing symptoms associated with chronic rhinosinusitis.


Q: What happens if I miss a scheduled application of Беконазе?

Protocols for a missed dose typically state that it should be administered as soon as it is remembered. However, if the next scheduled dose is nearly due, the missed dose is usually skipped to maintain the regular regimen and avoid double application.


Q: Does Беконазе help with post-nasal drip?

The medicine works by reducing inflammation and suppressing the production of excessive mucus in the nasal passages. This action is consistent with the relief of associated symptoms such as a runny nose and post-nasal drip.


Q: What happens if I stop using Беконазе suddenly?

If the medicine is stopped abruptly after long-term, continuous use, particularly in patients who were also using other forms of steroids, withdrawal symptoms such as muscular pain and tiredness may occur. Official documents describe that discontinuation is generally done gradually under medical supervision.


Q: Is Беконазе the same as Flonase or other nasal sprays?

No, Беконазе contains the active ingredient beclometasone dipropionate, which is the specific corticosteroid used in this formulation. Other common nasal steroids, such as Flonase, contain different active ingredients, such as fluticasone.


Q: Why do some people say they feel a strange smell or taste after using Беконазе?

Official safety documents list an unpleasant taste or smell as a possible adverse reaction. This is thought to be related to the localized effect of the spray or drainage of the medicine into the throat.


Q: What should I do if I accidentally swallow some of the spray?

Accidental ingestion of a small amount of the spray is generally considered unlikely to cause serious harm, as the systemic absorption of the medicine is low at recommended doses. Patients should contact a healthcare professional if they have concerns following accidental ingestion.


Q: Does Беконазе interact with common pain relievers like ibuprofen or paracetamol?

Specific and major drug interaction warnings for the combination of beclometasone nasal spray with common over-the-counter pain relievers, such as ibuprofen or paracetamol, are not typically listed in regulatory warnings.


Q: Does Беконазе cause drowsiness or affect my ability to drive?

The official product information does not generally list drowsiness as an expected side effect of this intranasal formulation, which acts locally in the nasal passages.


Q: Can Беконазе be used for non-allergy issues like a cold or sinus infection?

This medicine is indicated for treating chronic inflammatory conditions like allergic rhinitis. It is not approved for treating the common cold, which is a viral infection, and it should not be used if a patient has an untreated localized nasal infection.


Q: Is Беконазе available without a prescription in some places?

The regulatory status can vary by country and region. In some areas, the medicine may require a prescription, while in others, certain formulations may be classified as pharmacy-only or available over the counter.


Q: What's the difference between Беконазе and a regular saline nasal spray?

Беконазе is a medicated nasal spray containing a powerful corticosteroid to actively reduce inflammation. In contrast, a regular saline nasal spray is a non-medicated solution used primarily for washing, moisturizing, and clearing the nasal passages.


Q: Do I need to shake the Беконазе bottle before every use?

Yes, official administration guidelines for the aqueous suspension formulation typically instruct the user to gently shake the bottle before each scheduled use to ensure the active ingredient is properly mixed.


Q: Can people with diabetes use Беконазе?

Intranasal corticosteroids have low systemic absorption at recommended doses. However, patients with diabetes are often advised to monitor their condition closely when using any corticosteroid, given the drug class's potential for systemic effects.


Q: Is Беконазе safe to use if I have high blood pressure?

The intranasal medicine, due to its low systemic absorption, is not generally associated with changes in blood pressure and is not typically listed as being contraindicated for use in patients with hypertension.


Q: Why is it important to angle the nozzle away from the center of the nose?

The recommended administration technique involves angling the nozzle away from the nasal septum (the central dividing wall). This procedure is described as important to reduce the risk of irritating the septum, which could potentially lead to a rare side effect called nasal septal perforation.


Q: Is the sensation of burning or stinging in the nose a common side effect of Беконазе?

Yes, regulatory information specifically notes that local reactions such as burning, stinging, or irritation in the nasal passages are common side effects reported by users.


Q: Can Беконазе affect my sense of smell?

Changes to the sense of smell, including a temporary or sometimes persistent loss of smell (anosmia), have been reported as uncommon side effects in post-marketing reports.


Q: How is the effectiveness of Беконазе measured in clinical trials?

In studies for allergic rhinitis, effectiveness is measured using structured, patient-reported outcomes. A primary metric is the Total Nasal Symptom Score (TNSS), which quantifies the severity of symptoms like congestion, sneezing, itching, and a runny nose.


Q: Can Беконазе be used to treat swelling from a fractured nose?

No. Official safety warnings state that the medicine should not be used in patients who have recently experienced nasal trauma or surgery until the area has fully healed, due to the inhibitory effects of corticosteroids on wound healing.


Q: Is it safe to use Беконазе right before or after getting a flu shot?

Because this intranasal product is locally acting with low systemic absorption, it is generally unlikely to affect the body's response to a vaccine, unlike high doses of oral steroids. Patients with concerns about the concurrent use of the medicine with a vaccine are advised to consult a healthcare professional.


Q: Is Беконазе a drug that can be tested for on a standard drug test?

Corticosteroids, such as the active ingredient in this nasal spray, are not typically among the substances included in standard, routine drug screening panels.


Q: Can Беконазе interact with herbal supplements like St. John's Wort?

While the low systemic absorption suggests a low risk, St. John's Wort can potentially interfere with the metabolism of many medicines. Official guidance states that patients are advised to disclose the use of all supplements, including herbal remedies, to their healthcare provider.

How should Беконазе be stored and disposed of?

How to Store and Dispose of Beconase (Beclometasone Dipropionate Nasal Spray)

Official regulatory guidelines strictly define the storage and disposal requirements for Beconase to ensure stability and proper handling.

Storage Requirements

Mandatory Storage Conditions

The nasal spray must be stored at controlled room temperature, specifically between 20 C and 25 C (68 F and 77 F). It is critical to protect the medication from freezing as this can cause the device to malfunction. The product must be stored out of the sight and reach of children.

Shelf-Life

Once the bottle has been opened and used, the medicine must be discarded after three months.

Disposal Instructions

Unused or expired Beconase should not be disposed of in household trash or wastewater (e.g., flushing down the toilet or sink). The product must be disposed of in accordance with local requirements for pharmaceutical waste collection.

Attention! Always consult to a doctor or pharmacist before using pills or medicines.

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