Reese's Pinworm Medicine

Oral

Single or mixed infections due to susceptible worms

Adult: 10 mg/kg as a single dose.

Child: 10 mg/kg as a single dose.

Oral

Ascariasis

Adult: 5 mg/kg as a single dose. Max: 1 g/dose. For mass treatment programmes: 2.5 mg/kg as a single dose given 3-4 times a yr.

Oral

Necatoriasis

Adult: 10 mg/kg daily for 3-4 days or 20 mg/kg daily for 2 days.

Oral

Enterobiasis

Adult: 10 mg/kg repeated once after 2-4 wk. Max dose: 1 g/dose.

Oral

Trichinosis

Adult: 10 mg/kg daily for 5 days.

Reese's Pinworm Medicine belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections.

Reese's Pinworm Medicine is used to treat pinworms (enterobiasis; oxyuriasis).

Reese's Pinworm Medicine may also be used for other worm infections as determined by your doctor.

Reese's Pinworm Medicine works by paralyzing the worms. They are then passed in the stool.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, Reese's Pinworm Medicine is used in certain patients with the following medical condition:

• Common roundworm infection
• Hookworm infection
• More than one worm infection at a time

For patients taking Reese's Pinworm Medicine for hookworm infection :

• Anemia (iron-poor blood) may occur in patients with hookworm infections. Therefore, your doctor may want you to take iron supplements to help clear up the anemia. If so, it is important to take iron every day while you are being treated for hookworms. Do not miss any doses. Your doctor may also want you to keep taking iron supplements for up to 6 months after you stop taking Reese's Pinworm Medicine. If you have any questions about this, check with your doctor.

Usual Adult Dose for Enterobiasis

11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.

Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)

11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.

Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)

11 mg/kg base (maximum 1 g) orally daily for 3 days.

Usual Adult Dose for Ascariasis

11 mg/kg base (maximum 1 g) orally once.

Usual Adult Dose for Trichostrongylosis

11 mg/kg base (maximum 1 g) orally once.

Usual Adult Dose for Moniliformis Infection

11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.

Usual Pediatric Dose for Enterobiasis

>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.

Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)

>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.

Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)

>=2 years: 11 mg/kg base (maximum 1 g) orally daily for 3 days.

Usual Pediatric Dose for Ascariasis

>=2 years: 11 mg/kg base (maximum 1 g) orally once.

Usual Pediatric Dose for Trichostrongylosis

>=2 years: 11 mg/kg base (maximum 1 g) orally once.

Usual Pediatric Dose for Moniliformis Infection

>=2 years: 11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Reese's Pinworm Medicine is contraindicated in patients with hepatic disease.

Dose Adjustments

In the treatment of ascariasis, Reese's Pinworm Medicine may be used only if it has been determined that the worm load will not worsen obstruction.

Precautions

Reese's Pinworm Medicine is contraindicated in patients with hepatic disease.

When one individual in a household has pinworms, the entire household should be treated unless otherwise advised. Pinworm infections are easily transmitted to others in the same household.

Reese's Pinworm Medicine should be used with caution in patients with severe malnutrition or anemia. Supportive therapy is recommended for anemic, dehydrated, or malnourished patients prior to administration of the drug.

Other medications are known to antagonize the anthelmintic effect of Reese's Pinworm Medicine. Patients should be advised to consult with their physician before initiating any drug therapy while receiving Reese's Pinworm Medicine.

Dialysis

Data not available

Other Comments

The dose should be taken as a single oral dose. It may be taken alone or with milk or fruit juice.

Reese's Pinworm Medicine 2.9 g is approximately equivalent to 1 g of Reese's Pinworm Medicine (base).

See also:
What is the most important information I should know about Reese's Pinworm Medicine?

This medicine is contraindicated in patients with known hypersensitivity to the benzimidazole class of compounds or any components of this medicine.

Use Reese's Pinworm Medicine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Reese's Pinworm Medicine may be taken on an empty stomach or with food, milk, or juice.
• Shake well before using a dose of Reese's Pinworm Medicine.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• Wear tight underwear both day and night while taking Reese's Pinworm Medicine.
• Reese's Pinworm Medicine is usually prescribed as a single dose.
• Only one dose of Reese's Pinworm Medicine is required. If you forget to take Reese's Pinworm Medicine, take it as soon as you remember.

Ask your health care provider any questions you may have about how to use Reese's Pinworm Medicine.

See also:
What other drugs will affect Reese's Pinworm Medicine?

• Dexamethasone

Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when 8 mg dexamethasone was coadministered with each dose of albendazole (15 mg/kg/day) in 8 neurocysticercosis patients.

• Praziquantel

• Cimetidine

Albendazole sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n = 7) compared with albendazole (20 mg/kg/day) alone (n = 12). Albendazole sulfoxide plasma concentrations were unchanged 4 hours after dosing.

• Theophylline

The pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged following a single oral dose of albendazole (400 mg) in 6 healthy subjects.

See also:
What are the possible side effects of Reese's Pinworm Medicine?

Applies to Reese's Pinworm Medicine: oral suspension, oral tablet, oral tablet chewable

In addition to its needed effects, some unwanted effects may be caused by Reese's Pinworm Medicine (the active ingredient contained in Reese's Pinworm Medicine). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Reese's Pinworm Medicine, check with your doctor or nurse as soon as possible:

Rare

• Skin rash

Minor Side Effects

Some of the side effects that can occur with Reese's Pinworm Medicine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:

• Abdominal or stomach cramps or pain
• diarrhea
• dizziness
• drowsiness
• headache
• irritability
• loss of appetite
• nausea or vomiting
• trouble in sleeping

Reese's Pinworm Medicine is an antinematodal thiophene